Clinical trials
Severe Traumatic Brain Injury clinical trials
Below are recruiting severe traumatic brain injury clinical trials, each written for real people, not researchers. We’re tracking 226 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07119827Recruiting
Personality traits and recovery after brain injury
This study looks at how your personality might affect recovery after a serious brain injury or stroke. You and a family member will answer a short personality questionnaire to see if certain traits are linked to better recovery.
Verona, VRAges 18–80 - NCT07214415RecruitingPhase 2
Hyperbaric oxygen therapy for veterans with brain injury or mental health issues
This trial tests whether hyperbaric oxygen therapy (breathing pure oxygen in a pressurized chamber) can improve thinking, mood, and quality of life in veterans with mild traumatic brain injury, PTSD, anxiety, or depression. You must have already tried at least one evidence-based therapy like CBT or EMDR.
Boise, IdahoAges 18–75 - NCT07230002Recruiting
Navigating in virtual worlds after brain injury
This study looks at how people who had a moderate or severe traumatic brain injury at least 3 months ago walk and navigate in complex virtual environments. Participants will use virtual reality to test their movement strategies.
RennesAges 18–55 - NCT07237386Recruiting
Testing a smart insole for walking in people with brain or spinal cord injury
This study tests a special insole that measures how you walk, compared with a high-tech walking lab. It's for people with stroke, spinal cord injury, or brain injury who can walk on their own for 6 minutes.
GhentAges Any age - NCT06480838Recruiting
Brain blood flow and thinking after traumatic brain injury
This study looks at how the brain controls its own blood flow after a moderate to severe traumatic brain injury (TBI). It uses MRI scans and thinking tests to understand recovery and help improve care for people like you.
Dallas, TexasAges 18–80 - NCT07256704Recruiting
Hypnosis and Attention in Brain Conditions
This study tests whether hypnosis can help improve attention and focus in people with stroke, traumatic brain injury, or multiple sclerosis. It involves an EEG (a test that records brain activity) to see how the brain responds.
LucerneAges 18 years+ - NCT07269457RecruitingPhase 2
Vitamin D3 for recovery after mild to moderate brain injury
This trial tests if taking vitamin D3 can help reduce swelling and speed up recovery after a mild to moderate traumatic brain injury. It is for people who have low vitamin D levels.
LagosAges 18–65 - NCT07292766Recruiting
Metabolic Profiles After Severe Head Injury
This study looks at chemical changes in the body after a severe head injury. It aims to find markers that may help guide treatment.
Aksaray, AnkaraAges 18–65 - NCT07341074Recruiting
Early help for adults with mild traumatic brain injury
This study tests if offering early support soon after a mild head injury can help reduce ongoing symptoms. If you've recently had a mild traumatic brain injury (concussion) and are still having trouble, this program might help you recover better.
GroningenAges 18–70 - NCT07356167Recruiting
Neurosensory training for mild brain injury symptoms
This study tests a special training program that uses sound and head movements to help people with long-lasting symptoms after a mild brain injury or sudden sensory event. The goal is to see if this 'neurosensory' training can reduce problems like dizziness, headache, and brain fog.
Miami, FloridaAges 18 years+ - NCT07357090Recruiting
Carbon dioxide and brain waste clearance trial
This trial tests if breathing in carbon dioxide helps the brain clear waste. It may show how the brain heals after a traumatic brain injury (TBI).
Albuquerque, New MexicoAges 18–82 - NCT07385105Recruiting
CBT for insomnia after mild brain injury
This study tests whether a type of talk therapy called cognitive behavioral therapy for insomnia can help people with mild traumatic brain injury sleep better. It focuses on those who have had sleep problems for over a month.
Columbia, MissouriAges 18–60 - NCT02407028RecruitingPhase 2
Hyperbaric oxygen treatment for severe traumatic brain injury
This Phase 2 trial studies whether breathing oxygen in a pressurized chamber can improve outcomes after a severe traumatic brain injury. It is mainly for people with very low consciousness levels soon after injury, with careful safety checks.
San Diego, CaliforniaAges 16–65 - NCT02426255Recruiting
Study of serious injuries and complications after trauma
This study follows people with severe injuries (including head injuries and bleeding) to better understand serious complications that can happen after trauma. Your experience may help doctors predict and prevent these complications in the future.
AngersAges 15 years+ - NCT02592291Recruiting
Using a phone app to help manage long-term health needs
This study tests a mobile phone system that helps people with long-term, complex health conditions manage daily life and get support. If you can use a smartphone and pass the study checks, you may be able to try the self-management tools.
Pittsburgh, PennsylvaniaAges 12 years+ - NCT03160131Recruiting
Rehab program to improve vision after brain injury
This study looks at rehabilitation to improve vision after a brain injury. It may help people with significant vision problems regain everyday visual function.
Copenhagen, HellerupAges 14 years+ - NCT03321370Recruiting
Study of brain swelling after severe head injury surgery
This trial looks at changes in brain activity after severe traumatic brain injury (TBI) when patients need emergency skull surgery. The goal is to better understand what happens in the brain after surgery and whether earlier recognition could help care after injury.
Minneapolis, MinnesotaAges 18 years+ - NCT07404761Recruiting
Moving your arm after stroke or TBI
This study tests a device that uses mild electrical pulses and augmented reality (a computer overlay on real life) to help people who have arm or hand weakness after a recent stroke or brain injury regain movement.
HaifaAges 18 years+ - NCT07413562Recruiting
Nerve stimulation for memory problems after brain injury
This trial tests whether stimulating a nerve in the wrist (median nerve) can help improve thinking and memory problems in people who have had a recent traumatic brain injury. It is for adults with moderate injuries who have trouble with memory and thinking.
Beijing, Beijing MunicipalityAges 18–64 - NCT07473505Recruiting
Nerve block for PTSD in special operations veterans
This study tests if a specific nerve block (cervical sympathetic block) can help reduce trauma-related symptoms in Special Operations veterans with PTSD. The goal is to see if this treatment is safe and can improve how you feel.
Strongsville, OhioAges 18 years+ - NCT07485361Recruiting
Brain scanning in disorders of consciousness
This trial uses a portable brain scanner (fNIRS) to study brain activity in people with disorders of consciousness, like coma or minimally conscious states. It may help doctors better understand and track recovery in these patients. Healthy volunteers are also needed as a comparison group.
Los Angeles, CaliforniaAges 18 years+ - NCT07490418Recruiting
Brain injury screening for mild head trauma or neurological symptoms
This trial tests a device (TES HT100) to screen for brain injuries in people with mild head trauma or certain neurological symptoms. It aims to quickly identify who might need imaging or follow-up care.
Castel Volturno, CEAges 18 years+ - NCT07560631Recruiting
Facial Tracking to Monitor Brain Injury Recovery
This study uses camera technology to track subtle facial movements as a way to detect awareness and recovery in people with severe brain injuries. It may help doctors better understand and monitor patients who have suffered traumatic brain injury.
Stony Brook, New YorkAges 22–85 - NCT07606300Recruiting
Light Training to Help Light Sensitivity After Head Injury
This trial tests whether a training program using colored light targets can help reduce light sensitivity (photophobia) that some people experience after a traumatic brain injury. The training involves focusing your eyes on lights during several visits.
Columbus, OhioAges 18–80
Hear when a new Severe Traumatic Brain Injury trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for severe traumatic brain injury?
- Yes. Clin2 currently lists 226 recruiting severe traumatic brain injury studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a severe traumatic brain injury trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a severe traumatic brain injury trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.