Clinical trials
Ventilation clinical trials
Below are recruiting ventilation clinical trials, each written for real people, not researchers. We’re tracking 523 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT02708836Recruiting
Tests safer airway method to reduce anesthesia “waking up” issues
This study looks at whether a combined airway method during general anesthesia can reduce unpleasant or risky “emergence” problems as you wake up. It is for people having planned laparoscopic (camera) surgery and who can follow fasting and consent rules.
Hershey, PennsylvaniaAges 18 years+ - NCT03033251Recruiting
Compare high-flow oxygen to noninvasive ventilation for COPD flare-ups
This study compares two breathing support options for people hospitalized with a COPD flare-up and high carbon dioxide levels in the blood. It aims to see which option works better and is safer for breathing and recovery.
Toronto, OntarioAges 40 years+ - NCT03405779Recruiting
Ultrasound test to measure lung stress in ICU patients
This study tests a new ultrasound method to assess how much strain is happening in the lungs of critically ill adults on a breathing machine. It may help doctors better understand lung stress and guide care in the ICU.
Montreal, QuebecAges 18 years+ - NCT03581370RecruitingPhase 3
Short vs longer infusion antibiotic for ventilator lung infection
This Phase 3 study compares a shorter vs longer drip schedule of the antibiotic ceftolozane-tazobactam in ICU patients with a specific type of ventilator-associated pneumonia caused by Pseudomonas. It aims to find which infusion time works as well (or better) while treating the infection safely.
ToulouseAges 18 years+ - NCT03758508Recruiting
Noninvasive breathing support versus high-flow oxygen for pneumonia
This study compares two ways to help breathing in adults with pneumonia who have low oxygen levels: a noninvasive breathing machine versus high-flow oxygen. It aims to see which option helps patients breathe better and avoid getting worse.
MilanAges 18 years+ - NCT03963622Recruiting
Test of careful breathing support for severe lung distress
This study compares a more careful ventilation approach for people with severe lung breathing failure (ARDS). It aims to improve outcomes by using a specific strategy for how the ventilator controls breathing.
New York, New YorkAges 18 years+ - NCT04080440Recruiting
Checking readiness to remove the breathing tube after brain injury
This study looks at how to judge when it is safe to remove the breathing tube in people in the ICU after a brain injury. It may help improve timing and safety of extubation, when supported by a breathing trial and clinical stability.
AngersAges 18–75 - NCT05030337Recruiting
Closed-loop oxygen control for very preterm babies on ventilators
This trial tests a computer-guided (“closed-loop”) oxygen control system for very preterm babies who need breathing support. It aims to keep oxygen levels safer and more consistent than standard care.
LondonAges Any age - NCT05098717Recruiting
PEEP settings guided by lung pressure in pulmonary fibrosis
This trial tests whether using lung-pressure measurements to adjust ventilator PEEP (a breathing-support setting that keeps airways open) can help people with pulmonary fibrosis who are on a breathing machine for acute respiratory failure. It may improve breathing comfort and oxygenation by finding the best PEEP level for you.
ModenaAges 18–90 - NCT05117125Recruiting
Testing for markers in early ventilator lung infections
This study looks at changes (biomarkers) in the blood or other samples from people on a breathing machine. It may help doctors detect ventilator-associated pneumonia earlier and tailor treatment sooner.
DrammenAges 18 years+ - NCT05124977Recruiting
Antibiotic plan study for ventilator pneumonia in ICU
This trial tests an “antibiotic stewardship” approach—choosing and adjusting antibiotics in a smarter way—for a first episode of pneumonia in patients on a breathing machine. It may help ensure the right antibiotics are used at the right time, while avoiding unnecessary or overly broad treatment.
Clichy-sous-BoisAges 18 years+ - NCT05211661Recruiting
Study breathing muscle changes in people on a ventilator
This study looks at how the diaphragm (a key breathing muscle) changes during and after being on a breathing machine in the ICU. It may help researchers understand why breathing can get weaker after ventilation and how to measure it safely (including with MRI).
AachenAges 18–75 - NCT05348291Recruiting
Ventilation tubes for babies with frequent ear infections
This trial studies whether placing ventilation (ear) tubes in very young children can reduce how often ear infections happen. It focuses on babies under 1 year old who have a high pattern of repeat ear infections.
LundAges 1–2 - NCT05406570Recruiting
Personalized breathing settings for adults with severe ARDS
This trial tests a more tailored way to set the amount of air delivered by a ventilator in people with severe ARDS. The goal is to see if personalized breathing settings can improve breathing and heart-related monitoring while patients are in intensive care.
LyonAges 18 years+ - NCT05454332RecruitingPhase 4
Caffeine for premature babies right after birth
This study tests whether caffeine given to very premature babies around the time they move from fetus to newborn stage can improve outcomes. It may help babies who need support as they breathe and adapt after birth.
Porto Alegre, Rio Grande do SulAges Up to 2 hours - NCT05686850Recruiting
Noninvasive breathing support vs high-flow oxygen after ICU extubation
This study compares two breathing supports used after a breathing tube is removed in the ICU: a noninvasive ventilator (mask-based) versus high-flow nasal oxygen. It aims to see which one works better when patients develop breathing trouble soon after extubation.
BrusselsAges 18 years+ - NCT05687292Recruiting
Decision tool to shorten breathing machine time in children
This study tests whether a computer “decision support” tool can help doctors safely reduce how long a child stays on a breathing machine after heart surgery. It may help children get off mechanical ventilation sooner and recover faster.
Boston, MassachusettsAges 1 day–12 years - NCT05696093RecruitingPhase 3
Cotrimoxazole for step-down treatment of ventilator pneumonia
This trial tests whether switching from an initial antibiotic to cotrimoxazole (a specific antibiotic combination) can work as well—or better—for ventilator-associated pneumonia in ICU patients. It aims to see if “de-escalating” antibiotics can control the infection while keeping vital signs stable.
AmiensAges 18 years+ - NCT05726578Recruiting
Ultrasound checks of lung recruitment in preterm, ventilated babies
This trial studies how ultrasound of the heart and lungs can show which airspaces in the lungs are opening up (“lung recruitment”) in preterm babies who are having breathing trouble and need an advanced breathing machine. It may help clinicians better monitor lung recovery and adjust care.
AlexandriaAges 1 hour–3 days - NCT05751863Recruiting
Sedation-first vs usual care in ventilated trauma patients
This study compares how pain medicine and calming medicine are started in critically injured (trauma) adults who are on a breathing machine. It aims to see whether a specific “analgesia-first” approach can improve comfort and support breathing weaning.
Long Beach, CaliforniaAges 18 years+ - NCT05822869Recruiting
Testing early EIT monitoring in people with ARDS
This trial looks at monitoring people with ARDS (a serious lung condition) very early after breathing support starts, using a technology called EIT. The goal is to see whether this early monitoring can help guide care during the first critical hours.
Beijing, Beijing MunicipalityAges 18 years+ - NCT05843786RecruitingPhase 3
Interferon gamma for ventilator pneumonia in ICU
This trial tests whether a medicine called interferon gamma can improve outcomes in adults with a first episode of pneumonia that develops after being on a ventilator in the ICU. It is designed for specific ICU timing, infection severity, and immune marker levels, and it compares treatment on top of standard care.
LimogesAges 18 years+ - NCT05857774Recruiting
Study breathing muscle changes in ICU patients on ventilation
This study looks at how the muscles used for breathing work and change in ICU patients who are placed on breathing machines, then follows outcomes after they leave the hospital. It may help doctors better predict recovery and long-term health after ventilation.
Toronto, OntarioAges 18 years+ - NCT05950893Recruiting
Testing a device to measure breathing effort on ventilators
This trial checks whether a tool (called PMIvent) can safely and accurately track how hard you are breathing while you are on a ventilator set to “pressure support.” If it works well, it may help clinicians better understand breathing effort during this common type of ventilator care.
BeijingAges 18–85
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Common questions
- Are there clinical trials for ventilation?
- Yes. Clin2 currently lists 523 recruiting ventilation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a ventilation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a ventilation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.