Hematology
Blood & lymphatic clinical trials
Anemia, clotting disorders, and other conditions of the blood and lymphatic system. We’re tracking 5,086 recruiting studies in this area right now.
By phase
- Not applicable2,108
- Phase 21,118
- Phase 1823
- Phase 1/Phase 2484
- Phase 3349
- Phase 4126
- Phase 2/Phase 378
Top conditions
- Multiple Myeloma333
- Acute Myeloid Leukemia292
- Lymphoma182
- Sickle Cell Disease142
- Myelodysplastic Syndromes129
- Acute Lymphoblastic Leukemia123
- Chronic Lymphocytic Leukemia100
- Leukemia100
- Follicular Lymphoma74
- Hematologic Malignancy68
- Myelodysplastic Syndrome68
- Hodgkin Lymphoma67
- Mantle Cell Lymphoma62
- Anemia60
- Diffuse Large B Cell Lymphoma57
- Lymphedema49
- Non-Hodgkin Lymphoma49
- Small Lymphocytic Lymphoma49
Leading sponsors
- Institute of Hematology & Blood Diseases Hospital, China148
- M.D. Anderson Cancer Center147
- National Cancer Institute (NCI)96
- The First Affiliated Hospital of Soochow University68
- Memorial Sloan Kettering Cancer Center65
- Mayo Clinic61
- City of Hope Medical Center60
- Assistance Publique - Hôpitaux de Paris46
- St. Jude Children's Research Hospital43
- Peking University People's Hospital41
Where studies are running
- California406
- Texas186
- Maryland149
- Alabama146
- Arizona123
- Florida111
- Massachusetts101
- New York98
- Ohio71
- Minnesota68
Recruiting studies5,086 total
- NCT06331377Recruiting
Study of blood cell disorders for patients 1 year and older
This study looks at people with histiocytic disorders, which are rare conditions where certain immune cells grow too much. It aims to learn more about these disorders to improve diagnosis and treatment.
Rochester, MinnesotaAges 1 year+ - NCT07742488Recruiting
Statins and hormone therapy for cholesterol in menopause
This study looks at whether taking statins (cholesterol-lowering medicine) along with hormone replacement therapy (HRT) affects blood clotting in women going through menopause who have high cholesterol. It may help doctors understand how these medicines work together.
Pisa, ItalyAges 45–55 - NCT06912347Enrolling by invitation
Herbal therapy to prevent infection after stem cell transplant
This trial tests whether a special herbal treatment applied to the skin can help prevent infections around the bottom that are caused by diarrhea after a stem cell transplant. It may be an option for people who are getting a transplant for the first time.
Shanghai, Shanghai MunicipalityAges 14–70 - NCT06321289RecruitingPhase 1/Phase 2
Donor T cell therapy for B-cell lymphoma
This trial tests a new type of therapy where specially designed donor T cells target your lymphoma. It's for people with certain B-cell non-Hodgkin lymphomas that have not responded to or returned after standard treatments. You might join if you meet the health and disease criteria listed below.
Beijing, Beijing MunicipalityAges 18–75 - NCT07680595RecruitingPhase 1/Phase 2
Statins and folic acid for unstable carotid plaque
This trial tests if adding folic acid to a statin can help stabilize plaques in the carotid artery (neck artery) to prevent stroke. You may qualify if you have carotid plaque and are not already on certain supplements.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT07058103RecruitingPhase 2
Combination therapy for relapsed or refractory angioimmunoblastic T-cell lymphoma
This trial tests a combination of five drugs (tislelizumab, cyclophosphamide, mitoxantrone liposomes, chidamide, and prednisone) for patients with angioimmunoblastic T-cell lymphoma (AITL) that has come back or not responded to previous treatment. The goal is to see if this combination can shrink tumors or stop the disease from growing.
Xuzhou, JiangsuAges 18 years+ - NCT06906835Recruiting
Comparing two blood tests to guide iron treatment in dialysis patients
This trial tests whether a new blood test (reticulocyte hemoglobin) is better than the usual iron test (transferrin saturation) for guiding when to give iron to people on dialysis. If you have anemia (low red blood cells) from kidney disease, this study may help doctors find the best way to treat your iron levels.
Pathumwan, BangkokAges 18–80 - NCT03707262RecruitingPhase 1/Phase 2
Brother or sister donor transplant using kidney and stem cells
This study tests a combined approach for kidney transplant patients: standard living-donor kidney transplant plus an added “stem cell” component taken from the same sibling donor. It aims to improve transplant outcomes by trying to better control the immune response and reduce complications.
Los Angeles, CaliforniaAges 18 years+ - NCT06905106Recruiting
Polycythemia proteins and red blood cell study
This trial studies proteins and red blood cell production in people with polycythemia (high red blood cell count) to understand its causes. It may help improve care for patients with this condition.
DijonAges 18 years+ - NCT06731699RecruitingPhase 1
Testing FD-001 for blood cancers that returned or didn't respond
This trial tests a new drug, FD-001, for people with certain blood cancers (like leukemia, lymphoma, or myeloma) that have come back or stopped responding to standard treatments. The goal is to see if the drug is safe and how well it might work.
Chengdu, SichuanAges 18–80 - NCT05925504RecruitingPhase 2
Lowering luspatercept dose for lower-risk myelodysplastic anemia
This Phase 2 study tests whether gradually lowering the dose of luspatercept can help people with lower-risk myelodysplastic syndromes (MDS) who have anemia. It may help reduce side effects while still improving blood counts or symptoms.
Tianjin, Tianjin MunicipalityAges 18 years+ - NCT05925023Recruiting
Sirolimus for warm autoimmune hemolytic anemia after steroid failure
This trial studies sirolimus in adults with “warm” autoimmune hemolytic anemia (or Evans syndrome) when steroids have not worked or the anemia has returned. It may help control the immune attack on red blood cells, but there are specific safety checks for liver health and infections.
Beijing, Beijing MunicipalityAges 18–90 - NCT05665140RecruitingPhase 2/Phase 3
Newly diagnosed myeloma study using blood-marker risk groups
This Phase 2/3 trial tests whether matching treatment choices to a patient’s myeloma risk pattern (using blood and scan results) improves outcomes. It is for people with newly diagnosed, untreated, symptomatic multiple myeloma who may also receive transplant-related treatment.
BerlinAges 18–70 - NCT07680803RecruitingPhase 2
Gene therapy for transfusion-dependent beta-thalassemia
This trial tests a one-time gene therapy using your own stem cells to help you produce healthy red blood cells and reduce or eliminate the need for regular blood transfusions. It is for people with transfusion-dependent beta-thalassemia who are between 3 and 35 years old.
Rome, LazioAges 3–35 - NCT05749276RecruitingPhase 1
Daratumumab with chemo for older adults with high-risk AML
This Phase 1 study tests whether adding daratumumab to standard intensive chemotherapy (idarubicin and cytarabine) works safely in people age 60 or older with a higher-risk form of acute myeloid leukemia (AML). It may help improve outcomes, but the main goal is to find the best dosing and safety in this age group.
NantesAges 60 years+ - NCT03868722RecruitingPhase 2/Phase 3
Acalabrutinib plus venetoclax for high-risk CLL with infection risk
This study tests whether acalabrutinib plus venetoclax can control newly diagnosed chronic lymphocytic leukemia (CLL) in people who are at higher risk of infections or who likely need treatment soon. It aims to see if this combination can improve disease control while keeping patients safe.
CopenhagenAges 18 years+ - NCT05874674Recruiting
Testing nafamostat to reduce bleeding risk during dialysis
This pilot study tests whether nafamostat is safe for people on hemodialysis who have a high risk of bleeding. It may help clinicians find safer ways to manage blood clotting medicines during dialysis.
Wŏnju, KangwondoAges 18–99 - NCT05558319RecruitingPhase 3
New myeloma study comparing three treatment plans before transplant
This Phase 3 trial tests the best combination of medicines for newly diagnosed multiple myeloma patients who are headed to an autologous stem cell transplant (ASCT). It compares extended VRD plus versus Isa-VRD versus Isa-V-Iberdomide to see which approach works best and is tolerable.
Alcalá de Henares, MadridAges 18–65 - NCT06674096RecruitingPhase 2
Two chemotherapy sequences for elderly double expressor DLBCL
This trial tests a new sequence of two chemotherapy regimens (RLC followed by CR-CHOP) for elderly patients with a fast-growing DLBCL called double expressor lymphoma. The goal is to see if this approach is safe and effective for people who may not tolerate standard treatments.
Hangzhou, ZhejiangAges 65 years+ - NCT07032727RecruitingPhase 2
Olutasidenib plus targeted therapy for relapsed IDH1-mutated myeloid cancers
This trial tests a combination of olutasidenib with other targeted drugs for people with certain blood cancers that have returned or not responded to treatment. It focuses on patients who have both an IDH1 mutation and a second activating mutation in specific signaling genes.
Houston, TexasAges 18 years+ - NCT06182696RecruitingPhase 1/Phase 2
CAR-T cells targeting GPRC5D for relapsed multiple myeloma
This trial tests a new type of cell therapy (CAR-T cells) that targets a protein called GPRC5D on myeloma cells. It is for people with multiple myeloma that has come back or not responded to several prior treatments, including immunomodulators, proteasome inhibitors, and anti-CD38 antibodies.
Hangzhou, ZhejiangAges 18–75 - NCT04942886Enrolling by invitation
Preventing hepatitis B reactivation after stem cell transplant
This trial tests whether taking the antiviral medicine entecavir before and after a stem cell transplant can prevent hepatitis B from “waking up” again. It may help protect your liver during a high-risk treatment period.
SeoulAges 19–70 - NCT05625594RecruitingPhase 1
Test brain-directed CAR T cells for CNS lymphoma
This Phase 1 study tests a new type of immune therapy (CAR T cells) placed directly into the fluid around the brain to treat central nervous system (CNS) lymphoma. It mainly looks at safety and how well the treatment can control the lymphoma when other CNS treatments have not worked.
Duarte, CaliforniaAges 18 years+ - NCT03999229RecruitingPhase 1
Nitric-oxide therapy during your own blood return
This early study tests whether a nitric-oxide–based treatment (given during autologous blood transfusion) can affect how well your body handles the returned blood. It mainly needs healthy adults who can safely donate blood and follow medication and breathing/comfort requirements.
Cleveland, OhioAges 18–35
Common questions
- How many blood & lymphatic clinical trials are recruiting?
- Clin2 is tracking 5,086 recruiting hematology studies from the U.S. registry right now, out of 7,699 we cover in this area in total.
- What does “Blood & lymphatic” cover here?
- Anemia, clotting disorders, and other conditions of the blood and lymphatic system. We group each study into blood & lymphatic based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a blood & lymphatic trial near me?
- Use the search to filter blood & lymphatic studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.