Rheumatology & orthopedics
Bones, joints & muscles clinical trials
Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We’re tracking 4,610 recruiting studies in this area right now.
By phase
- Not applicable3,773
- Phase 2214
- Phase 4199
- Phase 1182
- Phase 3138
- Phase 1/Phase 270
- Phase 2/Phase 334
Top conditions
- Knee Osteoarthritis173
- Rheumatoid Arthritis131
- Fibromyalgia104
- Osteoporosis82
- Osteoarthritis71
- Rheumatoid Arthritis (RA)68
- Osteoarthritis, Knee65
- Shoulder Pain48
- Hip Osteoarthritis43
- Degenerative Disc Disease39
- Psoriatic Arthritis39
- Chronic Pain38
- Total Knee Arthroplasty38
- Systemic Lupus Erythematosus37
- Duchenne Muscular Dystrophy36
- Musculoskeletal Pain35
- Osteoarthritis (OA) of the Knee32
- Pain32
Leading sponsors
- Riphah International University85
- Istituto Ortopedico Rizzoli69
- Cairo University65
- Assistance Publique - Hôpitaux de Paris36
- Foundation University Islamabad31
- Mayo Clinic28
- Massachusetts General Hospital25
- National Taiwan University Hospital24
- Hacettepe University23
- Tanta University22
Where studies are running
- California206
- New York86
- Florida83
- Maryland76
- Arizona71
- Massachusetts71
- Texas66
- Alabama60
- Illinois50
- Pennsylvania47
Recruiting studies4,610 total
- NCT06109129Recruiting
Mollii Suit study for children with cerebral palsy who can walk
This trial tests whether wearing a special suit (Mollii suit) helps children with cerebral palsy who can walk move better and feel less discomfort. It aims to see if the suit can improve daily life.
AnkaraAges 4–18 - NCT05874154Recruiting
Nerve surgery vs botox for spastic foot after stroke
This trial compares two treatments—tibial nerve selective surgery and botulinum toxin (botox) injections—to improve a stiff, turning-in foot after stroke. It aims to use goal-based care to see which option works better for walking and foot function.
BronAges 18–100 - NCT05378841Recruiting
Surgery to reduce pain in finger osteoarthritis
This trial tests whether surgical “nerve disconnection” (joint denervation) can reduce pain from osteoarthritis in a finger joint. It focuses on people who have ongoing finger pain despite usual treatments for at least 3 months.
ParisAges 18 years+ - NCT06820515Recruiting
Blood disorder patient registry for all ages
This study is a registry (a large database) that collects information from people who have or may have a blood disorder. It helps researchers learn more about these conditions and improve care.
Hickory, North CarolinaAges Any age - NCT06818448Recruiting
Comparing rotator cuff repair methods for small tears
This trial compares two surgical techniques for repairing small rotator cuff tears (up to 2 cm). It tests if a newer method helps people recover better than the standard approach.
MechernichAges 18 years+ - NCT06822933Enrolling by invitation
Remote monitoring study for gout patients
This study tests whether using a smartphone or tablet to monitor your gout from home can help manage the condition. You may qualify if you have had at least one gout flare in the last year and have high uric acid levels.
Oslo, Please SelectAges 18 years+ - NCT06819475Recruiting
Muscle health study for childhood leukemia survivors
This study uses imaging to look at how well the mitochondria (the tiny power plants inside your muscle cells) are working. It compares survivors of childhood leukemia who have low muscle mass to healthy volunteers, to understand muscle health and find ways to help.
Memphis, TennesseeAges 18 years+ - NCT06819930Enrolling by invitation
Fibromyalgia fitness study for women aged 30-64
This study measures the functional capacity (daily movement and activity) of women with fibromyalgia compared to women without the condition. It helps understand how fibromyalgia affects physical fitness.
Barcelona, BarcelonaAges 30–64 - NCT06820489Recruiting
Comparing gum and bone healing after implant placement
This study tests three different ways to rebuild gum and bone around a new dental implant placed right after a tooth is pulled. It may help if you need a front tooth, canine, or premolar removed and have enough bone for the implant.
Ghent, East FlandersAges 20 years+ - NCT06820528Recruiting
Thumb arthritis surgery: is in-clinic therapy needed?
This trial compares recovery after thumb joint surgery with or without in-clinic physical therapy. It aims to see if patients can recover just as well with home exercises alone, which could reduce travel and costs.
Columbia, MissouriAges 18 years+ - NCT06819683RecruitingPhase 1
Testing a new oxygen sensor in people with and without mitochondrial myopathy
This study tests a tiny sensor that measures oxygen levels in muscle. It will help researchers understand how oxygen is used during exercise. If you have mitochondrial myopathy or are a healthy volunteer, you might be able to join.
Philadelphia, PennsylvaniaAges 18–65 - NCT06823206Recruiting
Movement training for shoulder pain from rotator cuff issues
This trial tests whether learning movement techniques combined with sensorimotor training (exercises that improve how your brain controls your shoulder) can help reduce chronic shoulder pain caused by rotator cuff problems. It may be a good fit if you have had shoulder pain for over three months with changes seen on MRI or ultrasound.
Hong KongAges 50 years+ - NCT06821607Recruiting
Telerehab for chronic low back pain
This study tests if online rehabilitation therapy can help people with ongoing low back pain. You would connect with a specialist from home.
Baltimore, MarylandAges 18–64 - NCT06820736Recruiting
Comparing drain methods after low back surgery
This study compares two different methods of using a tube (drain) to remove fluid after low back surgery. It aims to see which drain technique leads to fewer problems or better recovery for people having one or two levels of back surgery.
Minneapolis, MinnesotaAges 18–70 - NCT06818201Recruiting
Brain stimulation for ACL surgery recovery
This study tests if a gentle, noninvasive brain stimulation called tDCS can improve how your brain controls leg muscles and speeds up recovery after ACL surgery.
Valencia, ValenciaAges 16–40 - NCT06820190Recruiting
Numbing injection for pain after scoliosis fusion surgery
This trial is testing a new type of numbing injection near the spine to see how well it controls pain after scoliosis surgery. If you are having a posterior spinal fusion for idiopathic scoliosis, you may be able to join and receive the injection plus patient-controlled pain medicine.
Tanta, El-GharbiaAges 18 years+ - NCT06517056Recruiting
3D Knee Assessment for Active Duty Knee Pain
This trial tests a 3D camera device that measures how your knee moves. It may help find the best way to treat your front-of-knee pain and keep you mission-ready.
Honolulu, HawaiiAges 18–50 - NCT06807177Enrolling by invitation
Collagen injections for chronic neck pain
This trial tests if collagen injections into the neck can reduce chronic muscle pain and whether certain blood markers can show how well the treatment works. It may help if you have had neck pain for more than 12 weeks.
WarsawAges 18–65 - NCT06807424RecruitingPhase 3
Study of icotrokinra for active psoriatic arthritis
This trial tests a new medication called icotrokinra for people with active psoriatic arthritis (PsA). It aims to see how well the drug works and if it is safe, including for those who have tried other treatments.
Glendale, ArizonaAges 18 years+ - NCT06570291RecruitingPhase 3
Stem cell injection for knee osteoarthritis
This trial tests a new treatment using donor stem cells injected into the knee for people with moderate knee osteoarthritis. It aims to see if these cells can reduce pain and improve function.
Shanghai, ChinaAges 40–75 - NCT06807866RecruitingPhase 4
Duloxetine for pain after hip replacement surgery
This trial tests if duloxetine, a medication that helps with nerve pain, can reduce pain after hip replacement surgery. It may help patients who are having a first-time total hip replacement.
Miami, FloridaAges 18 years+ - NCT06805396RecruitingPhase 2
Adding palliative care support during radiation for bone cancer pain
This study tests whether adding a palliative care team early while you receive radiation for bone metastases can improve your quality of life and reduce symptoms.
AmersfoortAges Any age - NCT06813352Recruiting
Using facial expressions to recognize pain in fibromyalgia
This study uses artificial intelligence to look at facial expressions and other body signals to help recognize pain in people with fibromyalgia. It may lead to better ways to measure and treat pain.
Belo Horizonte, Minas GeraisAges 18–65 - NCT06812481Recruiting
Anticholinergic drugs and bone health in rheumatoid arthritis
This study looks at whether a type of medication (anticholinergic drugs) used for other conditions affects bone health in people with rheumatoid arthritis. It will help doctors understand if these drugs increase the risk of osteoporosis (weak bones) and if they should be avoided.
BalıkesirAges 18 years+
Common questions
- How many bones, joints & muscles clinical trials are recruiting?
- Clin2 is tracking 4,610 recruiting rheumatology & orthopedics studies from the U.S. registry right now, out of 7,529 we cover in this area in total.
- What does “Bones, joints & muscles” cover here?
- Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We group each study into bones, joints & muscles based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a bones, joints & muscles trial near me?
- Use the search to filter bones, joints & muscles studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.