Rheumatology & orthopedics
Bones, joints & muscles clinical trials
Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We’re tracking 4,843 recruiting studies in this area right now.
By phase
- Not applicable3,974
- Phase 2225
- Phase 4197
- Phase 1190
- Phase 3149
- Phase 1/Phase 275
- Phase 2/Phase 333
Top conditions
- Knee Osteoarthritis184
- Rheumatoid Arthritis140
- Fibromyalgia102
- Osteoporosis86
- Osteoarthritis74
- Osteoarthritis, Knee71
- Rheumatoid Arthritis (RA)66
- Shoulder Pain50
- Psoriatic Arthritis47
- Hip Osteoarthritis41
- Systemic Lupus Erythematosus41
- Duchenne Muscular Dystrophy39
- Degenerative Disc Disease38
- Chronic Pain37
- Total Knee Arthroplasty37
- Musculoskeletal Pain36
- Pain35
- Dermatomyositis31
Leading sponsors
- Riphah International University111
- Cairo University72
- Istituto Ortopedico Rizzoli71
- Assistance Publique - Hôpitaux de Paris37
- Foundation University Islamabad33
- Mayo Clinic29
- Massachusetts General Hospital27
- National Taiwan University Hospital25
- Chinese University of Hong Kong22
- Hacettepe University22
Where studies are running
- California211
- New York94
- Florida82
- Massachusetts76
- Arizona75
- Maryland73
- Texas65
- Alabama57
- Illinois55
- Pennsylvania50
Recruiting studies4,843 total
- NCT07004894Recruiting
Exercises vs massage for tennis elbow
This study compares two elbow treatments for tennis elbow: a re-education exercise program and a friction massage. It aims to see which better reduces pain and improves function.
IslamabadAges 25–50 - NCT07004881Recruiting
Comparison of two hand-on knee treatments for kneecap pain
This trial compares two gentle physical therapy techniques (Mulligan and Maitland mobilization) to see which works better for kneecap pain. If you have had knee pain for at least 2 months and it hurts with stairs, sitting, or squatting, this study may help find the best treatment for you.
IslamabadAges 18–40 - NCT07006883Recruiting
Yoga program for knee osteoarthritis
This trial tests whether a yoga program can improve daily function in people with knee osteoarthritis. It may help reduce pain and stiffness while improving mobility.
São PauloAges 40–80 - NCT07007338Recruiting
Calcium bone balance in children on dialysis starting cinacalcet
This study looks at how a medicine called cinacalcet affects calcium in the bones of children on dialysis. It may help doctors better understand bone health for kids like yours.
BordeauxAges 3–17 - NCT07008365RecruitingPhase 3
Measuring belly pressure and ultrasound to guide fluid removal in heart failure
This trial tests whether using belly pressure and bedside ultrasound can help doctors better manage fluid removal (decongestion) in people hospitalized with heart failure. The goal is to see if this approach leads to better outcomes.
ZaragozaAges 18–100 - NCT07009691Recruiting
Hydrogen water for ME/CFS patients
This trial tests whether drinking hydrogen-rich water can improve heart rate variability (a measure of nervous system function) in people with ME/CFS (myalgic encephalomyelitis/chronic fatigue syndrome). The goal is to see if this simple intervention helps reduce symptoms.
Stony Brook, New YorkAges 18–65 - NCT07009717Recruiting
Big toe strength and chemo nerve damage
This study looks at whether the strength of your big toe is related to nerve damage from chemotherapy. It involves a one-time test of your toe strength and some questionnaires. It may help researchers better understand how chemo affects your nerves.
Gainesville, FloridaAges 18–90 - NCT07010484Recruiting
New imaging tests for polymyalgia rheumatica
This trial tests if new imaging methods can help diagnose and treat polymyalgia rheumatica (PMR). It may be for you if you're over 50, have pain in your shoulders or hips, and haven't taken steroids for PMR in the last 2 months.
AarhusAges 50 years+ - NCT07011979Recruiting
IBD study for those at higher risk
This study watches people who might be more likely to get Inflammatory Bowel Disease (IBD). It looks at close family members of IBD patients, people with autoimmune diseases, and those with certain digestive issues who also have a specific blood marker (ASCA). The goal is to find early signs and possibly prevent the disease.
SeoulAges 10 years+ - NCT07013110RecruitingPhase 2
AI-guided precision therapy for active rheumatoid arthritis
This study tests a new, AI-powered treatment approach for rheumatoid arthritis. It's for people with active disease who haven't used certain biologic or targeted therapies in the last 6 months.
SingaporeAges 21 years+ - NCT07014787Recruiting
Balance and knee cartilage study
This study looks at how different stages of knee cartilage damage (chondromalacia) affect your balance. You will be tested on a special balance machine to help doctors understand how your knee problem might affect your stability.
GizaAges 18–40 - NCT07016672Recruiting
PRP vs. hyaluronic acid for advanced knee arthritis
This study compares two treatments—platelet-rich plasma (PRP) and hyaluronic acid (a lubricating injection)—for people with severe knee arthritis seen on MRI. The goal is to see which better reduces pain.
Toulon, VarAges 18 years+ - NCT07016802RecruitingPhase 1
Study of GenSci134 for growth hormone deficiency
This trial tests a new growth hormone treatment called GenSci134 in healthy adults and adults with growth hormone deficiency (AGHD). The goal is to see if it is safe and effective for people who need growth hormone replacement.
Beijing, Beijing MunicipalityAges 18–70 - NCT07017686Recruiting
Reboot Study: Nerve stimulation for rheumatoid arthritis
This study tests a device that sends mild electrical pulses to the vagus nerve in the abdomen to treat rheumatoid arthritis. It is for people whose arthritis has not improved after trying multiple medications.
Fitzroy, VictoriaAges 18–75 - NCT07017985Recruiting
Diabetes in patients having first lower back surgery
This study looks at how common diabetes is in people about to have their first lower back surgery (lumbar spine surgery). It aims to help doctors better understand the link between diabetes and spine health.
MassyAges 18 years+ - NCT07018336Recruiting
Mirror therapy vs virtual reality for arm recovery after stroke
This study compares two therapies—mirror therapy and virtual reality—to help improve arm and hand function in people who have had a stroke. It aims to find which approach works better for recovery.
Istanbul, GaziosmanpaşaAges 18–75 - NCT07018791RecruitingPhase 3
Art-based pain test for jaw joint disorder patients
This trial tests if using art can help measure pain in people with temporomandibular joint disorders (TMD). It may offer a new way to understand and manage your pain without surgery.
Jeddah, Mecca RegionAges 18 years+ - NCT07021820Recruiting
New light-based imaging for centronuclear myopathy
This study tests a new type of imaging that uses light and sound to look at muscles in people with centronuclear myopathy. It may help doctors see muscle changes more clearly. It does not involve any treatment or medicine.
Erlangen, BavariaAges 2 years+ - NCT07022197RecruitingPhase 1/Phase 2
BAFF-R CAR T cells for severe nerve and immune diseases
This trial tests a new treatment using your own immune cells (called BAFF-R CAR T cells) for people with severe nerve and immune diseases that have not improved with standard medicines. These cells are designed to target and destroy certain immune cells that may be causing your illness.
Tianjin, Tianjin MunicipalityAges 18–60 - NCT07022795Recruiting
Controlling oral habits for jaw pain relief
This trial tests behavioral techniques to help reduce harmful oral habits like teeth clenching or jaw tension, which can cause jaw pain and disorders. If you often clench or grind, this study may help you learn new habits to ease discomfort.
Toronto, OntarioAges 18 years+ - NCT07023094RecruitingPhase 4
Comparing two nerve blocks for kids' hip surgery
This trial tests two types of pain-relieving nerve blocks for children having hip surgery. One uses a PENG block with LFCB, the other an ESP block; the goal is to see which provides better pain control.
PoznanAges 2–16 - NCT07023523Recruiting
Controlling brain activity for chronic pain
This study tests if people with fibromyalgia can learn to control their own brain activity using real-time feedback from an MRI machine to reduce pain. It is designed to help those with long-term chronic pain find new ways to manage it.
Boston, MassachusettsAges 18–65 - NCT07025668Recruiting
Different exercises for biceps tendon shoulder pain
This trial compares different exercise approaches to treat long-term pain in the biceps tendon of the shoulder. It aims to find which types of movement help relieve pain and improve function for people with certain shoulder conditions.
AnkaraAges 18–50 - NCT07026084Recruiting
Biofeedback training for upper cross syndrome
This trial tests if using biofeedback during exercise can improve muscle strength and posture in people with upper cross syndrome. It may help if you have forward head posture, neck pain for over 3 months, and limited neck movement.
Rawalpindi, Punjab ProvinceAges 25–45
Common questions
- How many bones, joints & muscles clinical trials are recruiting?
- Clin2 is tracking 4,843 recruiting rheumatology & orthopedics studies from the U.S. registry right now, out of 7,987 we cover in this area in total.
- What does “Bones, joints & muscles” cover here?
- Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We group each study into bones, joints & muscles based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a bones, joints & muscles trial near me?
- Use the search to filter bones, joints & muscles studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.