Rheumatology & orthopedics
Bones, joints & muscles clinical trials
Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We’re tracking 4,843 recruiting studies in this area right now.
By phase
- Not applicable3,974
- Phase 2225
- Phase 4197
- Phase 1190
- Phase 3149
- Phase 1/Phase 275
- Phase 2/Phase 333
Top conditions
- Knee Osteoarthritis184
- Rheumatoid Arthritis140
- Fibromyalgia102
- Osteoporosis86
- Osteoarthritis74
- Osteoarthritis, Knee71
- Rheumatoid Arthritis (RA)66
- Shoulder Pain50
- Psoriatic Arthritis47
- Hip Osteoarthritis41
- Systemic Lupus Erythematosus41
- Duchenne Muscular Dystrophy39
- Degenerative Disc Disease38
- Chronic Pain37
- Total Knee Arthroplasty37
- Musculoskeletal Pain36
- Pain35
- Dermatomyositis31
Leading sponsors
- Riphah International University111
- Cairo University72
- Istituto Ortopedico Rizzoli71
- Assistance Publique - Hôpitaux de Paris37
- Foundation University Islamabad33
- Mayo Clinic29
- Massachusetts General Hospital27
- National Taiwan University Hospital25
- Chinese University of Hong Kong22
- Hacettepe University22
Where studies are running
- California211
- New York94
- Florida82
- Massachusetts76
- Arizona75
- Maryland73
- Texas65
- Alabama57
- Illinois55
- Pennsylvania50
Recruiting studies4,843 total
- NCT07129954Recruiting
Fear of Falling in Muscular Dystrophy Trial
This trial tests a treatment to help people with certain types of muscular dystrophy who are afraid of falling. It aims to improve confidence and walking safety.
Verona, veronaAges 16–65 - NCT07130630Recruiting
Pain and activity confidence in Vietnamese knee osteoarthritis
This study tests a questionnaire that measures how confident people with knee osteoarthritis feel about doing daily activities despite pain. Your answers will help doctors better understand and support Vietnamese-speaking patients.
Ho Chi Minh City, Ho Chi MinhAges 50 years+ - NCT07132333Recruiting
Personalized inflammation study for chronic conditions
This study uses advanced testing to understand inflammation in people with certain chronic inflammatory diseases, such as psoriasis, psoriatic arthritis, other types of arthritis, or inflammatory bowel disease. The goal is to tailor treatment to your specific needs.
TübingenAges 18 years+ - NCT07134010Recruiting
Sugar-water injections for frozen shoulder
This study tests a treatment called perineural injection therapy, where a sugar-water solution (dextrose) is injected around the nerves in your shoulder. It may help reduce pain and improve movement in people with frozen shoulder that hasn't improved with other treatments.
Kuala Selangor, SelangorAges 18 years+ - NCT07134244Recruiting
Predicting cartilage damage and pain after knee injury or early arthritis
This study uses computer models and MRI scans to predict how knee cartilage and pain may change over time in people with early osteoarthritis or a recent ACL tear. It aims to find better ways to manage these conditions and prevent long-term damage.
Aalborg, North DenmarkAges 18–70 - NCT07135765Recruiting
MRI muscle study for scoliosis in children
This study uses high-resolution MRI to look at back muscles in children with scoliosis (a curved spine). It may help doctors understand muscle differences between types of scoliosis.
GarchesAges 10–17 - NCT07136844Recruiting
Walking and arm movement study for nerve and muscle conditions
This study uses motion analysis to understand walking and arm function in adults with certain neurological or metabolic diseases. The goal is to find patterns that help doctors better manage these conditions.
LiègeAges 18 years+ - NCT07137754Recruiting
Physiotherapy for minor injuries in the emergency department
This study tests whether a physiotherapy-led care model in the emergency department can help people with minor muscle or bone injuries recover better and at a lower cost. If you join, you'll see a physiotherapist instead of a doctor for your arm or leg injury.
Aarhus NAges 18 years+ - NCT07138729Recruiting
Imaging test for rheumatoid arthritis inflammation
This trial tests a new imaging scan (SPECT) that uses a special tracer (99mTc-TCR-FAPI) to see inflammation in the joints of people with rheumatoid arthritis. It aims to help doctors better understand and track disease activity.
Beijing, Beijing MunicipalityAges 18–75 - NCT07138807Recruiting
Neck exercises for female nurses with neck pain
This study compares two types of neck exercises to see which works better for reducing neck pain and disability in female nurses. You may be able to join if you are a nurse with moderate neck pain and a tender spot in your upper back muscle, and haven't had treatment for it in the past month.
Faisalabad, Punjab ProvinceAges 18–30 - NCT07138963Recruiting
Gene study in children with congenital muscle weakness
This study looks at how genes affect symptoms in children with congenital myopathies or congenital muscular dystrophies. It may help doctors better understand these conditions.
CairoAges 1–18 - NCT07140367Recruiting
Artery treatment for inflammatory knee arthritis
This trial tests if a minimally invasive procedure that blocks small arteries can reduce pain and swelling in arthritic knees. It's for people with moderate knee osteoarthritis who still have pain after trying other treatments and are already considering knee replacement surgery.
Bologna, BolognaAges 40 years+ - NCT07141043Recruiting
Bone health study after kidney transplant
This study looks at bone and mineral disorders in people on dialysis, after a kidney transplant, or with bone thinning. It aims to understand how these conditions affect bone health.
IașiAges 20–70 - NCT07141069Recruiting
Art therapy for adults with chronic low back pain
This study tests whether making art (art therapy) can help adults with ongoing low back pain feel better. You would take part in art sessions to see if this approach reduces pain and improves your quality of life.
Hong Kong, Hong KongAges 18–59 - NCT07141082Recruiting
Art therapy for older adults with long-term back pain
This study tests whether expressive art therapy (like drawing, painting, or music) can help older adults manage chronic low back pain. It aims to reduce pain and improve quality of life without medication.
Hong KongAges 60 years+ - NCT07145229RecruitingPhase 2
Testing a new drug for acute gout flares
This trial tests a new medication, ABP-745, for people having an acute gout flare. It aims to see if the drug is safe and helps reduce pain and inflammation.
Peoria, ArizonaAges 18–70 - NCT07146256Recruiting
OPMD Natural History Registry Study
This study is building a national registry (a database) for people with Oculo-Pharyngeal Muscular Dystrophy (OPMD) in Israel. Joining will help researchers understand how OPMD progresses over time and may lead to better care.
Ramat GanAges 18 years+ - NCT07146776Recruiting
Injectable PRF and bone graft for gum disease bone defects
This trial tests a treatment for deep gum disease pockets using a combination of your own blood components (injectable platelet-rich fibrin) and a bone graft material. It aims to help regenerate bone lost to periodontitis.
Istanbul, ÜsküdarAges 18–65 - NCT07147764Recruiting
Pain education plus physiotherapy for jaw pain
This trial compares two treatments for long-lasting jaw or face pain: physiotherapy alone versus physiotherapy combined with education about how pain works. It aims to find which approach helps more.
Istanbul, KavacikAges 18–65 - NCT07149792RecruitingPhase 4
Personalized treatment study for psoriasis and joint health
This study tests whether a personalized treatment plan can help people with psoriasis and psoriatic arthritis, and also looks at how these conditions affect the heart. The goal is to find better ways to treat you and protect your heart health.
Taichung, TaiwanAges 18–75 - NCT07150000Recruiting
Rheumatic disease research study for patients and healthy volunteers
This study is for people with certain rheumatic conditions (like arthritis, lupus, or vasculitis) and for healthy volunteers. It aims to learn more about these diseases and improve how they are treated.
Bonn, North Rhine-WestphaliaAges 18 years+ - NCT07153276RecruitingPhase 4
Laser vs estrogen cream for vaginal dryness in Sjögren's
This trial compares two treatments for vaginal dryness in women with Sjögren's disease: a CO2 laser procedure versus a topical estrogen cream called promestriene. The goal is to see which option works better to relieve dryness and discomfort.
São Paulo, São PauloAges 30–65 - NCT07154654Recruiting
Long-term study of mexiletine in young children with myotonic disorders
This study follows children under 6 years old with genetic myotonic disorders who are taking or may take mexiletine. It helps doctors understand how well the medicine works and if it is safe over time.
Clermont-FerrandAges Up to 6 years - NCT07156110Recruiting
Dental implant study for back teeth
This trial is testing a type of dental implant for people missing one or more teeth in the back of the jaw. It aims to see how well the implant holds up over time and whether the surrounding bone stays healthy.
Roma, RMAges 18 years+
Common questions
- How many bones, joints & muscles clinical trials are recruiting?
- Clin2 is tracking 4,843 recruiting rheumatology & orthopedics studies from the U.S. registry right now, out of 7,987 we cover in this area in total.
- What does “Bones, joints & muscles” cover here?
- Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We group each study into bones, joints & muscles based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a bones, joints & muscles trial near me?
- Use the search to filter bones, joints & muscles studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.