Rheumatology & orthopedics
Bones, joints & muscles clinical trials
Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We’re tracking 4,611 recruiting studies in this area right now.
By phase
- Not applicable3,768
- Phase 2217
- Phase 4200
- Phase 1182
- Phase 3139
- Phase 1/Phase 271
- Phase 2/Phase 334
Top conditions
- Knee Osteoarthritis172
- Rheumatoid Arthritis132
- Fibromyalgia105
- Osteoporosis82
- Osteoarthritis71
- Rheumatoid Arthritis (RA)68
- Osteoarthritis, Knee64
- Shoulder Pain48
- Hip Osteoarthritis43
- Psoriatic Arthritis40
- Degenerative Disc Disease39
- Chronic Pain38
- Total Knee Arthroplasty38
- Duchenne Muscular Dystrophy37
- Systemic Lupus Erythematosus37
- Musculoskeletal Pain35
- Osteoarthritis (OA) of the Knee32
- Pain32
Leading sponsors
- Riphah International University85
- Istituto Ortopedico Rizzoli69
- Cairo University65
- Assistance Publique - Hôpitaux de Paris36
- Foundation University Islamabad31
- Mayo Clinic28
- Massachusetts General Hospital25
- National Taiwan University Hospital25
- Hacettepe University23
- Tanta University22
Where studies are running
- California207
- New York87
- Florida82
- Maryland76
- Arizona72
- Massachusetts71
- Texas67
- Alabama59
- Illinois51
- Pennsylvania48
Recruiting studies4,611 total
- NCT07796607Enrolling by invitation
Knee cartilage therapy research
This study looks at knee osteoarthritis to find new ways to treat it. If you have knee pain from worn-down cartilage, this research may lead to better therapies.
Kunming, YunnanAges Any age - NCT07796516RecruitingPhase 2
Telitacicept for difficult-to-treat rheumatoid arthritis
This trial tests if a new medication, telitacicept, is safe and effective for people with difficult-to-treat rheumatoid arthritis. It may be an option for patients who have not found relief from other treatments.
Hefei, AnhuiAges 18 years+ - NCT07798830Recruiting
Nerve block options for pain relief after hip replacement surgery
This study compares two types of nerve blocks to see which one provides better pain relief after hip replacement surgery. The blocks are given during the surgery to help reduce pain after the operation.
Tanta, El-GharbiaAges 18 years+ - NCT04441411Recruiting
Non-fusion surgery for teens with idiopathic scoliosis
This trial studies a “non-fusion” surgery approach for teenagers with a spinal curve that has worsened despite non-surgical treatments. It aims to see if this surgery can better treat adolescent idiopathic scoliosis while avoiding spinal fusion in eligible patients.
Amsterdam, North HollandAges 10–17 - NCT04725422Recruiting
Registry for children with nonbacterial bone inflammation
This study collects medical information (and imaging results) from children and teens with nonbacterial bone inflammation. It may help doctors better understand how this condition looks on scans and how it’s diagnosed, especially to rule out infection or cancer.
Seattle, WashingtonAges Up to 21 years - NCT06530459RecruitingPhase 2/Phase 3
The MUSE Study for Menopausal Joint Pain
This study tests whether a treatment can help women with joint pain and stiffness that started or worsened during menopause. It focuses on women who are within 5 years of menopause and have pain in multiple joints.
SingaporeAges 30–59 - NCT06091371Recruiting
Using a small implant for flatfoot in growing kids
This trial tests a new implant to treat flexible flatfoot in children. It may help reduce pain and improve foot function during growth.
BolognaAges 8–14 - NCT06091397Recruiting
Italian ankle replacement survey study
This study tests a new Italian questionnaire for people who have had total ankle replacement surgery. It helps doctors understand how well patients forget about their new ankle in daily life.
BolognaAges 25–80 - NCT06536582Recruiting
Nutrition’s role in PRGF treatment for shoulder tendon pain
This trial studies how diet affects the success of a special blood-based treatment (PRGF) for shoulder tendon pain. It may help you heal better from tendinopathy.
MilanAges 18–70 - NCT06525545Recruiting
Early Motion After Total Ankle Replacement
This study tests whether starting ankle movement early after total ankle replacement helps you recover faster and with better results. It is for adults with osteoarthritis who are getting their first ankle replacement.
Bologna, ItaliaAges 18–80 - NCT07789340Recruiting
Radiofrequency treatment for knee osteoarthritis pain
This study compares two types of radiofrequency treatment to reduce knee pain from osteoarthritis. It may help people whose knee pain has not improved with other treatments like physical therapy or injections.
Tanta, El-GharbiaAges 50 years+ - NCT07788404Recruiting
Study of rifampin levels in patients with bone or joint staph infections
This study looks at how the antibiotic rifampin behaves in the body when used to treat staph infections in bones or joints. It may help doctors better dose the drug for future patients.
Paris, ParisAges 18 years+ - NCT07785362Enrolling by invitation
Brain stimulation for teens with fibromyalgia or chronic pain
This study tests a non-invasive brain stimulation technique to see if it can reduce pain in teenagers and young adults with fibromyalgia or other long-lasting muscle and bone pain that hasn't responded to usual treatments. It aims to help calm overactive pain signals in the brain.
Genova, GEAges 10–21 - NCT07791784Recruiting
Pain relief and shoulder exercises for shoulder pain
This study tests a program that combines pain management education with shoulder exercises to help people with long-lasting shoulder pain. The goal is to see if this approach reduces pain and improves daily function.
Ballerup MunicipalityAges 18–65 - NCT07788976Recruiting
Comparing two jaw surgery techniques for better healing
This study looks at two different ways of doing jaw surgery to see which one gives better stability and healing. If you are already planning to have jaw surgery, this study may help improve how well your jaw stays in place after the procedure.
Istanbul, FatihAges 18–65 - NCT07788872Recruiting
Talking tool to help prepare for back surgery
This study tests a dialogue support tool that helps you and your surgeon talk through your back surgery and recovery. It aims to make your meetings clearer and more helpful.
Oslo, NordbyhagenAges 18 years+ - NCT07784998Recruiting
Weight-bearing physiotherapy for knee osteoarthritis
This study compares how men and women respond to a special type of physiotherapy that uses gradual weight-bearing exercises to reduce knee pain and improve function. It may help you if you have moderate knee osteoarthritis and are looking for a non-surgical treatment option.
Gujar Khan, Punjab ProvinceAges 40–60 - NCT07784231RecruitingPhase 1/Phase 2
Light therapy for stroke-related muscle stiffness
This study tests a light-based therapy (photobiomodulation) to see if it can help reduce muscle stiffness in people recovering from a stroke. Participants will continue their usual rehabilitation while receiving this additional treatment.
São Paulo, São PauloAges 18 years+ - NCT07788846Recruiting
Comparing methods to stop bone bleeding during finger or toe amputation
This trial tests different ways to stop bleeding from bone during finger or toe amputation surgery. It compares using collagen, bone wax, or pressure to see which works best and is safest.
Kolār, KarnatakaAges 18 years+ - NCT07786701Recruiting
Surgery for camptodactyly: skin flap versus graft
This trial tests a surgical method to fix camptodactyly (a bent finger) using a skin flap technique versus a skin graft. It's for people of any age who meet the stiffness criteria and haven't had prior finger surgery.
São Paulo, São PauloAges Any age - NCT07789288Recruiting
Hard collar use after cervical spine fusion
This study compares recovery outcomes with and without a hard cervical collar after posterior cervical fusion surgery. You may qualify if you have degenerative disk disease and are scheduled for this type of spine surgery.
Washington D.C., District of ColumbiaAges 18 years+ - NCT07791134Recruiting
Effect of connective tissue massage on pain in fibromyalgia
This study is testing whether a special type of massage (connective tissue massage) can help reduce pain sensitivity in women with fibromyalgia. It aims to see if this massage therapy can improve pain symptoms.
AnkaraAges 18–65 - NCT07785401Recruiting
Platelet-rich plasma plus hyaluronic acid for knee osteoarthritis
This study tests whether adding platelet-rich plasma (PRP) to hyaluronic acid injections improves knee osteoarthritis pain and function better than hyaluronic acid alone. You may be eligible if you have moderate knee osteoarthritis and no other knee problems.
Warsaw, Masovian VoivodeshipAges 18 years+ - NCT07790328Recruiting
Long-term safety of the IntraSPINE implant for low back pain
This study checks how safe and effective the IntraSPINE implant is over time for people with low back pain from degenerative discs. The implant is placed in your spine to support it, and this trial helps see if it continues working well for years.
SaranAges 18 years+
Common questions
- How many bones, joints & muscles clinical trials are recruiting?
- Clin2 is tracking 4,611 recruiting rheumatology & orthopedics studies from the U.S. registry right now, out of 7,492 we cover in this area in total.
- What does “Bones, joints & muscles” cover here?
- Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We group each study into bones, joints & muscles based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a bones, joints & muscles trial near me?
- Use the search to filter bones, joints & muscles studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.