Rheumatology & orthopedics
Bones, joints & muscles clinical trials
Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We’re tracking 4,611 recruiting studies in this area right now.
By phase
- Not applicable3,768
- Phase 2217
- Phase 4200
- Phase 1182
- Phase 3139
- Phase 1/Phase 271
- Phase 2/Phase 334
Top conditions
- Knee Osteoarthritis172
- Rheumatoid Arthritis132
- Fibromyalgia105
- Osteoporosis82
- Osteoarthritis71
- Rheumatoid Arthritis (RA)68
- Osteoarthritis, Knee64
- Shoulder Pain48
- Hip Osteoarthritis43
- Psoriatic Arthritis40
- Degenerative Disc Disease39
- Chronic Pain38
- Total Knee Arthroplasty38
- Duchenne Muscular Dystrophy37
- Systemic Lupus Erythematosus37
- Musculoskeletal Pain35
- Osteoarthritis (OA) of the Knee32
- Pain32
Leading sponsors
- Riphah International University85
- Istituto Ortopedico Rizzoli69
- Cairo University65
- Assistance Publique - Hôpitaux de Paris36
- Foundation University Islamabad31
- Mayo Clinic28
- Massachusetts General Hospital25
- National Taiwan University Hospital25
- Hacettepe University23
- Tanta University22
Where studies are running
- California207
- New York87
- Florida82
- Maryland76
- Arizona72
- Massachusetts71
- Texas67
- Alabama59
- Illinois51
- Pennsylvania48
Recruiting studies4,611 total
- NCT07732062Recruiting
Emotion-focused therapy for chronic pain patients using medical cannabis
This study tests a new type of talking therapy (vEAET-H) to see if it helps people with chronic pain who are already using medical cannabis. The goal is to find out if adding this therapy can improve pain and well-being.
Tel AvivAges 18 years+ - NCT07724691Recruiting
Comparing two shoulder therapies for frozen shoulder
This study compares two types of gentle shoulder movements (mobilizations) to treat frozen shoulder. The goal is to reduce pain and help you move your arm more easily.
Lahore, Punjab ProvinceAges 30–50 - NCT07724847Recruiting
Validating new criteria for diagnosing axial spondyloarthritis
This study aims to confirm new classification criteria for axial spondyloarthritis, a type of inflammatory arthritis affecting the spine and sacroiliac joints. Participants with chronic back pain lasting at least 3 months and starting before age 45 will undergo a series of tests to see if these new criteria better identify the condition.
Beijing, Beijing MunicipalityAges 18–45 - NCT07724470Recruiting
Stretching techniques for neck and arm pain
This study tests two types of stretching to see which one works better for neck pain that spreads into the arm. If you have had this pain for more than a month, this trial might help find a way to move better and feel less pain.
Lahore, Punjab ProvinceAges 30–60 - NCT05607966Recruiting
Knee replacement follow-up study for ORIGIN® implant
This study follows people who need a total knee replacement using the ORIGIN® implant. It’s meant to see how well the implant works and how people do over time with routine clinic visits.
AntwerpAges 18–99 - NCT06118736Recruiting
Guided bone growth to prevent hip problems in children with cerebral palsy
This trial tests a surgery to guide the growth of the upper thigh bone (femur) to keep the hip joint from sliding out of place in children with spastic cerebral palsy. It aims to prevent further hip migration and avoid more serious hip problems later.
AmsterdamAges 2–8 - NCT06184451Recruiting
TENS with exercise for knee osteoarthritis
This study tests if adding TENS (a pain-relieving electrical stimulation) to a standard exercise program helps people with knee osteoarthritis feel better and move better.
São PauloAges 40–75 - NCT06607731Recruiting
Alcohol gel treatment for aggressive angiomas
This trial studies a treatment using a special gelled alcohol to shrink aggressive angiomas (abnormal blood vessel growths). It aims to see if the procedure is safe, feasible, and works well.
Saint-Priest-en-JarezAges 18 years+ - NCT04576169Recruiting
Comparing treatment options for a TFCC tear in the wrist
This trial looks at which treatment works best for a specific kind of wrist cartilage (TFCC) tear. It may help you choose the most effective option if you have ulnar-sided wrist pain that didn’t improve with non-surgical care.
CopenhagenAges 18–65 - NCT06630975Recruiting
Knee alignment surgery comparison for children
This trial compares two surgical methods to correct knee alignment in children whose bones are still growing. It will help doctors know which approach works better and is safer.
AsyutAges 2–18 - NCT03728478RecruitingPhase 3
Step-up and step-down treatment for newly diagnosed arthritis
This Phase 3 study tests whether children with early juvenile idiopathic arthritis do better by starting with one treatment approach and adjusting (stepping up or stepping down) based on how their arthritis responds. It may help find the safest, most effective long-term plan for controlling symptoms with fewer side effects.
Genova, GEAges 2–17 - NCT07719452Enrolling by invitation
Strengthening exercise for chronic low back pain
This study tests if adding a specific low back strengthening exercise to standard physical therapy helps people with long-lasting low back pain. It is for Tricare beneficiaries who have had back pain for at least 3 months without leg pain.
Fort Sam Houston, TexasAges 18–65 - NCT02540915Recruiting
Pediatric spine and chest wall registry study at Children’s Hospital Colorado
This study keeps a registry of kids’ spine, back, and chest wall conditions to help researchers understand how these problems affect children over time. It may help by improving knowledge that can lead to better care, though it is mainly about tracking information.
Aurora, ColoradoAges Up to 17 years - NCT07715136RecruitingPhase 1
BCMA-CD19 CAR-T for Refractory Inflammatory Myopathy
This trial tests a new type of cell therapy (BCMA-CD19 cCAR-T) for people with inflammatory myopathy that hasn't improved with standard treatments. The goal is to see if this treatment can help control the disease.
Chengdu, SichuanAges 18–60 - NCT07715201Recruiting
Amino acid drink for strength and recovery in active men
This study tests whether a special amino acid supplement helps trained men get stronger, perform better, and recover faster from workouts. You'll take the supplement daily and follow a 10-week supervised training program.
Toronto, OntarioAges 18–45 - NCT07721142RecruitingPhase 4
Chinese medicine and Western medicine for hard-to-treat rheumatoid arthritis
This trial combines traditional Chinese herbal medicine with standard Western treatments for people with rheumatoid arthritis that hasn't responded well to at least two prior medications. It aims to see if the combination is more effective and safe.
ShanghaiAges 18–70 - NCT07723014Recruiting
Fascial vs muscle techniques for sacroiliac joint pain
This study compares two hands-on treatments for sacroiliac joint dysfunction, a common cause of lower back and hip pain. It aims to see which approach better reduces pain, improves movement, and helps with daily activities.
Lahore, Punjab ProvinceAges 30–45 - NCT07721220Recruiting
Nerve gliding moves for strength and endurance in athletes
This study tests whether a gentle nerve-stretching technique (neurodynamics) can improve leg strength and endurance in athletes. If you're 18–30, currently active in sports or intense training, and have no recent leg injury or surgery, you may be able to join.
High Point, North CarolinaAges 18–30 - NCT07720401Recruiting
Exercise during dialysis for posture problems
This study tests if doing gentle exercise during dialysis can help improve posture problems like a rounded upper back or forward head tilt. It is a small, early-stage study to see if the exercises are safe and might help.
IsfahanAges 18–80 - NCT07721766Recruiting
How muscle type affects strength training results
This study looks at how your muscle's natural energy use affects how well it grows with weight training. It may help you understand your own response to exercise.
Jyväskylä, Central FinlandAges 18–39 - NCT07719699Recruiting
Vibration and Pilates for chronic low back pain
This study tests if whole-body vibration or Pilates exercises can reduce pain and improve balance and movement in people with long-lasting low back pain. It aims to find a helpful treatment for chronic back pain that has lasted more than 12 weeks.
Lahore, Punjab ProvinceAges 18–40 - NCT07718815Recruiting
HLA B leader study in psoriatic arthritis
This study looks at a specific genetic marker (HLA B leader) in people with psoriatic arthritis compared to healthy individuals. It may help researchers understand how this gene affects the disease.
Amiens, PicardieAges 18 years+ - NCT07721116Recruiting
AI Study of Knee Imaging and Treatment Results
This study uses artificial intelligence (AI) to better understand knee images from healthy people and those with knee arthritis. It aims to predict how well knee injections might work for you.
Taipei, TaiwanAges 18 years+ - NCT07715188Recruiting
Low dose radiation for osteoarthritis
This trial tests if a very low dose of radiation can help relieve pain from osteoarthritis in joints like hips, knees, hands, shoulders, ankles, or elbows. It is for people whose pain has not improved with standard treatments or who want to try a gentler option before considering surgery.
Philadelphia, PennsylvaniaAges 18 years+
Common questions
- How many bones, joints & muscles clinical trials are recruiting?
- Clin2 is tracking 4,611 recruiting rheumatology & orthopedics studies from the U.S. registry right now, out of 7,492 we cover in this area in total.
- What does “Bones, joints & muscles” cover here?
- Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We group each study into bones, joints & muscles based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a bones, joints & muscles trial near me?
- Use the search to filter bones, joints & muscles studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.