Rheumatology & orthopedics
Bones, joints & muscles clinical trials
Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We’re tracking 4,841 recruiting studies in this area right now.
By phase
- Not applicable3,975
- Phase 2223
- Phase 4196
- Phase 1191
- Phase 3149
- Phase 1/Phase 274
- Phase 2/Phase 333
Top conditions
- Knee Osteoarthritis185
- Rheumatoid Arthritis142
- Fibromyalgia102
- Osteoporosis88
- Osteoarthritis74
- Osteoarthritis, Knee72
- Rheumatoid Arthritis (RA)64
- Shoulder Pain50
- Psoriatic Arthritis47
- Hip Osteoarthritis41
- Systemic Lupus Erythematosus41
- Duchenne Muscular Dystrophy39
- Chronic Pain38
- Degenerative Disc Disease38
- Total Knee Arthroplasty38
- Musculoskeletal Pain36
- Pain35
- Dermatomyositis31
Leading sponsors
- Riphah International University110
- Cairo University72
- Istituto Ortopedico Rizzoli71
- Assistance Publique - Hôpitaux de Paris37
- Foundation University Islamabad34
- Mayo Clinic29
- Massachusetts General Hospital27
- National Taiwan University Hospital25
- Chinese University of Hong Kong22
- Hacettepe University22
Where studies are running
- California210
- New York94
- Florida80
- Massachusetts76
- Arizona75
- Maryland73
- Texas65
- Alabama57
- Illinois54
- Pennsylvania50
Recruiting studies4,841 total
- NCT07650396RecruitingPhase 3
Steroid Injections for Long-Term Achilles Tendon Pain
This study tests whether steroid injections can help people with chronic Achilles tendon pain (the tendon at the back of your heel) who haven't improved with physical therapy and exercise. The injection is designed to reduce inflammation and pain in the middle part of the tendon.
RotterdamAges 18–65 - NCT06379321Recruiting
Triathlon Hinge Knee System Study
This study looks at how well the Triathlon Hinge Knee system works for people who need a complex knee replacement. It helps your surgeon know if this implant is a good option for you.
Weston, FloridaAges Any age - NCT06431191Enrolling by invitation
Anchor stitch or not in rotator cuff repair
This study tests whether adding a small 'anchor' stitch to the bone during a standard rotator cuff repair helps improve healing. It is for people with a moderate-sized tear who have not had prior shoulder surgery.
Beijing, Beijing MunicipalityAges 20–60 - NCT07155837Enrolling by invitation
TENS for pain after first knee replacement surgery
This study tests if a TENS device, which uses mild electrical pulses to relieve pain, helps people recover better after their first total knee replacement. It might reduce pain and improve movement.
Adana, AdanaAges 18 years+ - NCT06449495Recruiting
Virtual reality therapy for balance and coordination in kids
This trial tests whether a virtual reality (VR) program can help children with balance or coordination problems improve their movement skills. It's for kids ages 4 to 17 who can walk and follow simple instructions.
Bosisio Parini, LeccoAges 4–17 - NCT06124482Recruiting
Study of a new knee replacement implant
This trial tests a new knee replacement implant called the FHK®-CK. It is for people who need a new knee due to arthritis or to replace a failed knee implant.
BeaumontAges 18 years+ - NCT06837298Recruiting
Fava bean extract supplement for muscle recovery
This trial tests whether a supplement made from fava bean protein can help your muscles recover strength after exercise. You would take the supplement for about 2 weeks and have your muscle function tested before and after.
Bradenton, FloridaAges 18–45 - NCT06189495RecruitingPhase 2
Study of Genakumab for lung scarring from connective tissue disease
This study tests a new injected medication (Genakumab) for people with connective tissue disease-related lung scarring. It aims to see if it helps stabilize or improve lung function safely.
Beijing, Beijing MunicipalityAges 18–75 - NCT06344481Recruiting
Testing a new knee cartilage implant for pain relief
This trial tests a new implant (Hyalex) designed to repair damaged knee cartilage in people ages 21 to 65. If you have a painful cartilage defect that hasn't improved with standard treatments, this study may offer a new option to restore your knee surface.
LodzAges 21–65 - NCT06376981RecruitingPhase 3
Hyaluronic acid injection for shoulder tendon pain
This trial tests if an injection of hyaluronic acid (a natural lubricant) can reduce pain and improve function in people with shoulder tendinopathy (irritation of a tendon). It’s for those who haven’t gotten better with other treatments like rest or physical therapy.
La Roche-sur-YonAges 18–65 - NCT03642795Recruiting
French questionnaire study for people with rheumatoid arthritis
This study checks whether a French questionnaire about rheumatoid arthritis care answers works well. You may help by completing the survey if you have rheumatoid arthritis and meet medication and consent requirements.
BordeauxAges 18 years+ - NCT07314099Recruiting
Study of the Breizh Fabribus program for assistive devices
This study looks at the Breizh Fabribus program, which helps people get personalized assistive devices. It aims to see if the program helps improve your daily life.
Brest, FinistèreAges Any age - NCT03441165Recruiting
Measure knee looseness during ACL and meniscus surgery
This trial checks how loose the knee feels during surgery for ACL reconstruction, ACL revision, or meniscus transplantation. The goal is to better assess knee stability during the operation, which may help surgeons choose the best repair.
Bologna, ItaliaAges 14–65 - NCT07148466Recruiting
Shoulder and arm exercises for stroke with shoulder blade issues
This trial tests if specific shoulder and arm exercises can improve movement and walking in people who had a stroke and have shoulder blade problems. It may help if you have some muscle tightness but can still follow instructions.
Islamabad, Punjab ProvinceAges 40–65 - NCT07304076Recruiting
JHG002 Injection for Chronic Low Back Pain
This study tests if JHG002 injections (made from human placenta) are safe and effective for treating chronic low back pain. It may help people who have had low back pain for at least 6 months and rate their pain as a 5 or higher on a 0–10 scale.
Seoul, Gangdong-guAges 19–70 - NCT06237647Recruiting
Comparing injections for partial rotator cuff tears
This study compares three types of injections—steroids, PRP (platelet-rich plasma), and PRP combined with hyaluronic acid—to see which works best for partial rotator cuff tears. If you have shoulder pain from a partial tear, this trial may help find the most effective treatment for you.
Kaohsiung City, SanminAges 20–85 - NCT07419633Recruiting
Study on supplements to improve strength and thinking in older adults
This trial tests if two supplements, HMB and 2-HOBA, taken alone or together, can help improve muscle strength and mental function in healthy adults over 65. The goal is to see if these supplements can improve overall quality of life.
Montreal, QuebecAges 65 years+ - NCT07297771Recruiting
Shoulder muscle activity during different exercises
This trial looks at how a specific shoulder muscle works during different exercises. It may help people understand better ways to strengthen or rehab the shoulder.
Ankara, AltındagAges 18–40 - NCT07263945RecruitingPhase 1
Prosthetic Foot Stiffness and Walking in Below-Knee Amputation
This study tests how different prosthetic foot stiffness levels affect walking, balance, and comfort in people with a below-knee amputation who use either a bone-anchored implant or a traditional socket. Participating may help match the right foot to your needs and improve your daily mobility.
Aurora, ColoradoAges 18 years+ - NCT06238076Recruiting
Universal surgical device for jaw reconstruction
This trial tests a universal surgical device for rebuilding the lower jaw using a bone flap from the leg. It aims to make the procedure more reliable and easier for patients needing reconstruction of the front part of the jaw.
ToulouseAges 18 years+ - NCT07614555Recruiting
Breathing methods during back surgery recovery
This study compares two ways doctors control your breathing during lumbar disc herniation (slipped disc) surgery. Researchers want to see which method keeps your lungs healthier during the operation.
AnkaraAges 18–65 - NCT07061067Recruiting
How symptom duration affects lower back surgery results
This study looks at how long your symptoms have lasted before lower back surgery and whether that affects your recovery. If you're planning a lumbar spine operation and have symptoms like back or leg pain, this trial may help doctors understand the best timing for surgery.
Kafr ash Shaykh, KafrelsheikhAges 18 years+ - NCT06371755Recruiting
Comparing two bone density tests: ultrasound vs X-ray
This study compares two ways to measure bone density: a standard X-ray method (DXA) and a newer ultrasound method (REMS). If you are a woman scheduled for a DXA scan, you may help researchers see if the ultrasound test is just as accurate and easier to use.
Milan, MIAges 30–80 - NCT07330921Recruiting
Testing a new 3D seating system for kids with motor issues
This trial is testing a new 3D seating system designed for children with motor control problems. It aims to see if this system helps them sit better and be more comfortable.
Zaragoza, ZaragozaAges 2–6
Common questions
- How many bones, joints & muscles clinical trials are recruiting?
- Clin2 is tracking 4,841 recruiting rheumatology & orthopedics studies from the U.S. registry right now, out of 7,937 we cover in this area in total.
- What does “Bones, joints & muscles” cover here?
- Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We group each study into bones, joints & muscles based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a bones, joints & muscles trial near me?
- Use the search to filter bones, joints & muscles studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.