Rheumatology & orthopedics
Bones, joints & muscles clinical trials
Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We’re tracking 4,841 recruiting studies in this area right now.
By phase
- Not applicable3,975
- Phase 2223
- Phase 4196
- Phase 1191
- Phase 3149
- Phase 1/Phase 274
- Phase 2/Phase 333
Top conditions
- Knee Osteoarthritis185
- Rheumatoid Arthritis142
- Fibromyalgia102
- Osteoporosis88
- Osteoarthritis74
- Osteoarthritis, Knee72
- Rheumatoid Arthritis (RA)64
- Shoulder Pain50
- Psoriatic Arthritis47
- Hip Osteoarthritis41
- Systemic Lupus Erythematosus41
- Duchenne Muscular Dystrophy39
- Chronic Pain38
- Degenerative Disc Disease38
- Total Knee Arthroplasty38
- Musculoskeletal Pain36
- Pain35
- Dermatomyositis31
Leading sponsors
- Riphah International University110
- Cairo University72
- Istituto Ortopedico Rizzoli71
- Assistance Publique - Hôpitaux de Paris37
- Foundation University Islamabad34
- Mayo Clinic29
- Massachusetts General Hospital27
- National Taiwan University Hospital25
- Chinese University of Hong Kong22
- Hacettepe University22
Where studies are running
- California210
- New York94
- Florida80
- Massachusetts76
- Arizona75
- Maryland73
- Texas65
- Alabama57
- Illinois54
- Pennsylvania50
Recruiting studies4,841 total
- NCT06368245Recruiting
Study on extra rods for long spinal fusion surgery
This study looks at whether adding extra rods during a long spinal fusion surgery helps the fusion last longer. It is for adults aged 45 and older who had this type of surgery between 2014 and 2020.
Redwood City, CaliforniaAges 45 years+ - NCT03650673Recruiting
Study of early finger osteoarthritis symptoms over time
This study follows people with early finger (hand) osteoarthritis symptoms to better understand how the condition starts and changes. You may be asked for blood tests, symptom checks, and imaging to see what’s happening in the joints.
MontpellierAges 18–60 - NCT06345625Recruiting
Balance and walking with head movement in older adults
This study looks at how older adults keep their balance and walk when their head is moving. You may be asked to stand or walk while your head gently moves, so researchers can understand how your body reacts.
AntwerpAges 65–100 - NCT03772119Recruiting
Child surgery follow-up study for a spine bone shape issue
This study follows children aged 3–10 who need surgery for a specific type of spine bone shape problem (hemivertebra). It aims to track outcomes after the operation and how well follow-up is completed.
BordeauxAges 3–10 - NCT07655921Recruiting
Enhanced recovery after knee replacement surgery
This trial tests a special care plan called ERAS to help people recover faster after total knee replacement. It compares this plan to standard care to see if it reduces hospital stay and improves recovery.
Karachi, SindhAges 50–70 - NCT06720779Recruiting
Virtual rehab platform for knee replacement patients
This trial tests a virtual rehab platform for people recovering from knee replacement surgery. It may help you do your rehab exercises more easily at the hospital.
Barakaldo, Basque CountryAges 18–85 - NCT02301182Enrolling by invitation
Compare two hip implant types for younger hip arthritis
This trial compares two different hip implant designs in people ages 40–65 with primary hip osteoarthritis. It looks at how well the hip works afterward—especially function and everyday results.
AarhusAges 40–65 - NCT07667114Recruiting
Wrist ligament repair surgery trial
This trial tests a surgical technique to repair a torn ligament in the wrist (the scapholunate ligament) using a part of a nearby tendon. It may be an option for people with this specific wrist injury who meet the health requirements.
Berlin, State of BerlinAges 18 years+ - NCT07162948Recruiting
Home monitoring technology for ICU recovery
This study tests a smart technology box that helps monitor your health at home after a stay in the ICU. It may help you and your doctors keep track of your recovery more easily.
Leiden, South HollandAges 18 years+ - NCT06420648Recruiting
Active vs. Passive Hand Therapy After Tendon Repair
This study compares two different hand therapy programs after a tendon repair in one finger. It will help determine which movement approach—active or passive—works best for recovery.
Ha'ilAges 25–50 - NCT06438432Recruiting
Trunk exercises for young children with cerebral palsy
This study tests whether special trunk exercises can help young children with cerebral palsy improve their balance and walking. It compares children who do the exercises with those who get usual care.
NancyAges 1.5 years–6 years - NCT07699562Recruiting
EMG device study in healthy people and ICU patients
This study tests a device that records muscle activity (EMG) in healthy volunteers and critically ill patients in the ICU. It aims to learn how well the device works in different groups, which could help monitor muscle function in the future.
Evanston, IllinoisAges 18–90 - NCT06409559Recruiting
Comparing two surgical methods for hip socket fractures
This study compares two ways to fix a specific type of hip socket fracture (posterior wall fracture) using a rim plate or a buttress plate, with or without extra screws. It aims to find the best approach for healing.
Cincinnati, OhioAges 18 years+ - NCT07651215Enrolling by invitation
Short-Stem Shoulder Replacement Surgery Outcomes Study
This study looks at how well a newer type of shoulder replacement surgery works. Researchers are checking X-rays and patient function for people who had this specific short-stem surgery at least 2 years ago.
LinzAges 18 years+ - NCT07111286Recruiting
Imagining movements to help chronic low back pain
This trial tests whether imagining movements (motor imagery) can help improve daily function and reduce pain in people with chronic low back pain. You will participate in a rehabilitation program, and if you are in the motor imagery group, you will also practice mentally rehearsing specific movements.
DijonAges 18 years+ - NCT07641621Recruiting
Chiropractic Ankle Treatment and Jump Performance Study
This study tests whether chiropractic ankle manipulation improves how high and powerfully you can jump. Researchers will work with recreationally active adults to see if this treatment affects athletic performance.
Seneca Falls, New YorkAges 18–35 - NCT06367491Recruiting
National database of bone metastases
This study is a national database that collects information from people with cancer that has spread to their bones from a solid tumor. By joining, you will help doctors learn more about bone metastases and improve care for future patients.
Imola, BolognaAges 18 years+ - NCT05786313Recruiting
Open-door neck surgery plan for cervical spinal narrowing
This study looks at a more tailored and standardized surgical approach for people with neck spinal narrowing and spinal cord symptoms. It may help doctors compare and improve how well surgery works for different patients.
Xi'an, Shannxi ProvinceAges 28–85 - NCT07126262RecruitingPhase 2
Vosoritide for growth in infants with hypochondroplasia
This study tests a daily injection called vosoritide to see if it helps children with hypochondroplasia grow taller. It is for babies and toddlers up to 35 months old who are shorter than average for their age.
Phoenix, ArizonaAges birth–3 years - NCT06858358Recruiting
Robot vs. standard knee replacement for severe arthritis
This trial compares a robot-assisted knee replacement technique to the standard approach for people with severe knee arthritis. It aims to see which method leads to better recovery and outcomes.
Cluj-Napoca, ClujAges Any age - NCT06396247RecruitingPhase 2/Phase 3
Daily leg exercises to improve walking
This study tests a simple daily leg-strengthening routine to see if it helps people who have trouble walking short distances. You'll do easy resistance exercises at home, which might make it easier to walk and move around.
Hershey, PennsylvaniaAges 65 years+ - NCT06269354Recruiting
3D-printed implant for large lower-limb bone defects
This trial is testing a new way to treat large bone defects in the lower leg or thigh using a custom 3D-printed titanium implant. It may help people whose bone didn't heal after injury, infection, or tumor removal.
Beijing, HaidianAges 18–90 - NCT06447922Enrolling by invitation
Metal Levels After Knee Replacement
This study measures metal levels in the blood after knee replacement surgery. It may help researchers understand how metal from the new joint affects the body.
Rochester, MinnesotaAges 18–100 - NCT06268795Recruiting
Comparing biopsy vs. aspiration for shoulder/elbow revision surgery
This study compares two methods—biopsy (taking a small tissue sample) and aspiration (drawing fluid)—to see which one better detects infection in people having repeat shoulder or elbow replacement surgery. The results will help doctors choose the best test for future patients.
Wigan, LancashireAges 18 years+
Common questions
- How many bones, joints & muscles clinical trials are recruiting?
- Clin2 is tracking 4,841 recruiting rheumatology & orthopedics studies from the U.S. registry right now, out of 7,937 we cover in this area in total.
- What does “Bones, joints & muscles” cover here?
- Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We group each study into bones, joints & muscles based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a bones, joints & muscles trial near me?
- Use the search to filter bones, joints & muscles studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.