Rheumatology & orthopedics
Bones, joints & muscles clinical trials
Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We’re tracking 4,841 recruiting studies in this area right now.
By phase
- Not applicable3,975
- Phase 2223
- Phase 4196
- Phase 1191
- Phase 3149
- Phase 1/Phase 274
- Phase 2/Phase 333
Top conditions
- Knee Osteoarthritis185
- Rheumatoid Arthritis142
- Fibromyalgia102
- Osteoporosis88
- Osteoarthritis74
- Osteoarthritis, Knee72
- Rheumatoid Arthritis (RA)64
- Shoulder Pain50
- Psoriatic Arthritis47
- Hip Osteoarthritis41
- Systemic Lupus Erythematosus41
- Duchenne Muscular Dystrophy39
- Chronic Pain38
- Degenerative Disc Disease38
- Total Knee Arthroplasty38
- Musculoskeletal Pain36
- Pain35
- Dermatomyositis31
Leading sponsors
- Riphah International University110
- Cairo University72
- Istituto Ortopedico Rizzoli71
- Assistance Publique - Hôpitaux de Paris37
- Foundation University Islamabad34
- Mayo Clinic29
- Massachusetts General Hospital27
- National Taiwan University Hospital25
- Chinese University of Hong Kong22
- Hacettepe University22
Where studies are running
- California210
- New York94
- Florida80
- Massachusetts76
- Arizona75
- Maryland73
- Texas65
- Alabama57
- Illinois54
- Pennsylvania50
Recruiting studies4,841 total
- NCT06450834Enrolling by invitation
Ostene in planned open back spine surgery
This trial tests an experimental bone healing material, Ostene, during spine surgery. It may help reduce scar tissue and improve fusion. You are likely eligible if you are having planned open back surgery for nerve decompression and fusion.
Baltimore, MarylandAges 18–88 - NCT04449146Recruiting
Ultrasound guide for shoulder position during standing test
This study uses ultrasound (a non-radiation imaging tool) to help check the best way to hold your shoulder blade while standing. It’s aimed at people having a reverse shoulder replacement on their own shoulder joint, to see if this positioning method can improve care or planning.
BrestAges 18–99 - NCT06098586Recruiting
Nerve surgery vs exercise for wrist arthritis
This study compares two treatments for wrist arthritis: a surgery that cuts certain wrist nerves to stop pain signals, versus structured hand exercises. It may help if you have chronic wrist pain from a specific type of arthritis and haven't had previous wrist nerve surgery.
MalmöAges 18 years+ - NCT07417436Recruiting
Graded motor imagery for foot or ankle osteoarthritis
This study tests a technique called graded motor imagery to see if it can reduce pain and improve movement in people with foot or ankle osteoarthritis. The treatment involves specific mental exercises, so it might help if you have chronic ankle pain.
Antalya, AntalyaAges 18 years+ - NCT03231150Recruiting
Study for heel pain from plantar fasciitis
This trial studies treatments for ongoing heel pain caused by plantar fasciitis (pain in the band on the bottom of your foot). If you qualify, you may receive an injection treatment and be compared with a control group to see what works best.
Philadelphia, PennsylvaniaAges 18 years+ - NCT07637383Recruiting
Exercise Program to Improve Daily Function in Hospital Care
This study tests whether a structured exercise program can help patients in intermediate care hospitals regain their ability to do everyday activities like walking and self-care. The program is designed for people recovering from illness or injury.
Manresa, BarcelonaAges 65 years+ - NCT07050277RecruitingPhase 3
Morphine for bladder issues after knee replacement
This study tests whether adding morphine to spinal anesthesia can reduce trouble urinating after a second knee replacement surgery. It may help you avoid needing a catheter after surgery.
Toronto, OntarioAges 21 years+ - NCT03621306Recruiting
DXA scan study for accurate, reliable measurements
This study checks how precisely and consistently a DXA (dual-energy X-ray) scan measures body features in healthy adults. It may help future patients by improving the accuracy of scans used to guide health decisions.
University Park, PennsylvaniaAges 18 years+ - NCT06108063RecruitingPhase 1/Phase 2
Losartan to prevent knee stiffness after replacement
This study tests whether losartan, a blood pressure medicine, can prevent excessive scar tissue (arthrofibrosis) after a total knee replacement. Participants receive losartan or a placebo for 6 months after surgery to see if it improves knee motion and reduces stiffness.
Vail, ColoradoAges 18 years+ - NCT07627854Recruiting
Cold therapy after knee replacement surgery
This study compares two ways to reduce pain and swelling after total knee replacement: a special cold wrap (cryocuff) versus a standard ice pack. You'll help researchers understand which method works better for your recovery.
Kremmen, BrandenburgAges 18 years+ - NCT06806514Recruiting
Exercise and muscle strength in chronic low back pain
This trial measures how well you can use your arms and how strong your breathing and other muscles are if you have chronic low back pain. It aims to understand the links between these factors to improve future treatments.
KırşehirAges 18–65 - NCT06808022Enrolling by invitation
Back exercises before spine surgery
This trial studies whether doing back exercises before spine surgery helps improve recovery. If you are having spine surgery and can safely do physical therapy, you may be able to join.
La Jolla, CaliforniaAges 18 years+ - NCT06281184Enrolling by invitation
Long-term follow-up of methotrexate for hand osteoarthritis
This study follows up on people who took part in the MERINO trial to see if methotrexate has lasting benefits for hand osteoarthritis. It aims to understand how the drug affects pain and joint health over 30 months.
OsloAges 18 years+ - NCT07605013Recruiting
Neck Exercises for Office Workers: Building Strength and Function
This study tests whether specific neck mobilization techniques (gentle movements and stretches) can improve neck strength and function in desk workers. You would be a healthy control participant to help researchers understand how these techniques work in people without existing neck pain.
IstanbulAges 18–40 - NCT07084454Enrolling by invitationPhase 3
Remote geriatric care for older adults starting cancer treatment
This trial tests whether remote health assessments and support can improve care for adults 65+ who are starting a new cancer treatment. You'd participate from home via telehealth visits.
Rio de Janeiro, Rio de JaneiroAges 65 years+ - NCT06083896RecruitingPhase 1
Pelvic bone cancer treatment with light-activated nails
This trial tests a new way to treat cancer that has spread to the pelvic bone. It uses a special nail that is activated by light to help stabilize the bone and reduce pain, while also improving your ability to move around after surgery.
Houston, TexasAges 18 years+ - NCT06079567Recruiting
Study of FSHD2 progression over 18 months
This study follows people with FSHD2 over 18 months to learn how the disease progresses and affects daily life. No new drugs are tested—just regular check-ups and an MRI scan.
LeuvenAges 18–75 - NCT03608280Recruiting
3D-printed implant vs own bone for rebuilding eye socket
This study compares two ways to rebuild part of the eye socket bone: a 3D-printed implant versus using the patient’s own bone. It may help show which approach works better to restore eye position and symptoms like double vision after an injury or surgery.
Pierre-BéniteAges 18–90 - NCT07291128Recruiting
VOJTA therapy for children with ataxic cerebral palsy
This trial tests a special movement therapy called VOJTA technique to help improve balance and coordination in children with ataxic cerebral palsy. It may offer a gentle way to help your child move better.
Lahore, Punjab ProvinceAges 2–6 - NCT07613333Recruiting
Exercise Program for New Mothers
This study tests an exercise program designed for women who have given birth within the past 2 years. Researchers want to learn how exercise affects energy levels and overall health after pregnancy.
Waukesha, WisconsinAges 18 years+ - NCT06727708Recruiting
Comparing two exercise programs for fitness in adults 30-65
This study is testing two different 12-week exercise programs to see which one better improves physical fitness and body composition. It might be a good fit if you're a healthy adult aged 30-65 who is new to strength training.
Leibnitz, Styria, StyriaAges 30–65 - NCT07289412Recruiting
Meniscus repair study with or without ligament surgery
This study looks at how well meniscus repairs (using the all-inside technique) work over time, both when done alone and when combined with ligament reconstruction. It may help you understand the success of this surgery for your knee.
BolognaAges 12–65 - NCT07409103RecruitingPhase 2
Testing ELV001 for active rheumatoid arthritis
This study tests a new medication, ELV001, for people with active rheumatoid arthritis who haven't improved enough with methotrexate and a TNF inhibitor. The goal is to see if different doses of ELV001 are safe and can help reduce joint pain and swelling.
Gilbert, ArizonaAges 18–75 - NCT07286630Enrolling by invitation
Disability and fear avoidance in physical therapists
This study looks at how common disability and fear-related beliefs are among Egyptian physical therapists who have long-term low back pain. If you qualify, you will answer questionnaires about your pain, your thoughts about movement, and how it affects your daily life.
CairoAges 25–55
Common questions
- How many bones, joints & muscles clinical trials are recruiting?
- Clin2 is tracking 4,841 recruiting rheumatology & orthopedics studies from the U.S. registry right now, out of 7,937 we cover in this area in total.
- What does “Bones, joints & muscles” cover here?
- Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We group each study into bones, joints & muscles based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a bones, joints & muscles trial near me?
- Use the search to filter bones, joints & muscles studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.