Rheumatology & orthopedics
Bones, joints & muscles clinical trials
Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We’re tracking 4,841 recruiting studies in this area right now.
By phase
- Not applicable3,975
- Phase 2223
- Phase 4196
- Phase 1191
- Phase 3149
- Phase 1/Phase 274
- Phase 2/Phase 333
Top conditions
- Knee Osteoarthritis185
- Rheumatoid Arthritis142
- Fibromyalgia102
- Osteoporosis88
- Osteoarthritis74
- Osteoarthritis, Knee72
- Rheumatoid Arthritis (RA)64
- Shoulder Pain50
- Psoriatic Arthritis47
- Hip Osteoarthritis41
- Systemic Lupus Erythematosus41
- Duchenne Muscular Dystrophy39
- Chronic Pain38
- Degenerative Disc Disease38
- Total Knee Arthroplasty38
- Musculoskeletal Pain36
- Pain35
- Dermatomyositis31
Leading sponsors
- Riphah International University110
- Cairo University72
- Istituto Ortopedico Rizzoli71
- Assistance Publique - Hôpitaux de Paris37
- Foundation University Islamabad34
- Mayo Clinic29
- Massachusetts General Hospital27
- National Taiwan University Hospital25
- Chinese University of Hong Kong22
- Hacettepe University22
Where studies are running
- California210
- New York94
- Florida80
- Massachusetts76
- Arizona75
- Maryland73
- Texas65
- Alabama57
- Illinois54
- Pennsylvania50
Recruiting studies4,841 total
- NCT07628413Recruiting
Exercise Methods for Neck and Shoulder Pain
This study compares two types of gentle exercise programs—Egoscue and Feldenkrais—to help people with chronic neck pain and poor posture. Both programs focus on retraining muscles and improving how your body moves, and the study will measure which approach works better.
Lahore, Punjab ProvinceAges 25–45 - NCT06794632Recruiting
Hand osteoarthritis self-management program
This trial tests a group program to help people with hand osteoarthritis manage daily activities better. It focuses on peer learning and support to improve your ability to do everyday tasks.
Copenhagen, Capital RegionAges 18 years+ - NCT06261424Recruiting
Exercise program for spastic ataxia types ARSACS and SPG7
This study tests whether a supervised exercise program (including pool exercises) can help people with certain types of hereditary ataxia. The goal is to see if it reduces symptoms like muscle stiffness and coordination problems.
Baie-Saint-Paul, QuebecAges 16 years+ - NCT02366221Enrolling by invitation
Study of long-term outcomes after complex arm or leg injuries
This study looks at how people do long-term after complex injuries to the arm or leg, after their usual care is finished. It may help doctors understand what outcomes to expect and improve future treatment planning.
Ages 18 years+ - NCT05432895Recruiting
Compare moving vs fixed night splints for heel pain
This study compares two types of night splints to treat early plantar fasciitis (heel pain). It aims to see which splint type helps your symptoms and walking more after nighttime use.
Palo Alto, CaliforniaAges 18–99 - NCT03415828Recruiting
Testing ethanol gel versus steroid gel for low back disc pain
This study compares two gels put on or into the painful disc area: an ethanol gel versus a steroid gel. It is for adults with long-lasting low back disc pain that did not improve with usual non-surgical care.
BordeauxAges 18 years+ - NCT07079865Recruiting
Nerve stimulation for pain after spine fracture
This trial tests a 60-day nerve stimulation treatment to reduce pain and improve mobility after a recent spine fracture caused by osteoporosis. It may help patients who still have significant pain despite over-the-counter pain relievers.
Avenel, New JerseyAges 18 years+ - NCT05183542Recruiting
Surgery guided by an improved bone scan measurement for back pain
This trial studies whether a more precise bone scan measurement (SPECT/CT) can help guide surgery planning for people with long-lasting lower back pain. It may help surgeons choose and measure the surgery in a more standardized way for certain spine conditions.
Vandœuvre-lès-NancyAges 18 years+ - NCT07487987Recruiting
Imagery and exercises for chronic neck pain
This trial tests whether imagining movements (motor imagery) and doing special neck exercises can help people with long-term neck pain. You may be eligible if your neck pain has lasted at least 3 months and is at least moderate, and you haven't had recent neck surgery or therapy.
Konya, KaratayAges 18–65 - NCT07639424RecruitingPhase 4
New cartilage regeneration treatment for knee repair
This study tests a new platform to help repair damaged knee cartilage. If your knee has a specific type of cartilage damage, this treatment might help restore function and reduce pain.
Daegu, DaeguAges 19–64 - NCT03404778Enrolling by invitation
Collecting data on reverse shoulder implants for weak rotator cuff
This study collects real-world information about a reverse shoulder implant used when the rotator cuff is badly damaged. It may help improve how these implants are chosen and how well they work for pain relief and improving arm function.
Towson, MarylandAges 18 years+ - NCT06311058Recruiting
Protein supplement study for ACL surgery recovery
This trial tests whether a protein supplement can help you recover strength and muscle after ACL surgery. You will continue your standard rehab and take a protein drink daily for several weeks.
Houston, TexasAges 16–40 - NCT07497100Recruiting
Arm function and daily life in hemiplegic cerebral palsy
This study looks at how arm and hand function affects daily activities in children with hemiplegic cerebral palsy. It aims to help understand how to improve participation in everyday tasks.
CairoAges 5–8 - NCT07496983Recruiting
Using platelet-rich plasma (PRP) for tennis elbow
This study tests a treatment for tennis elbow called platelet-rich plasma (PRP), which uses your own blood to help the tendon heal. It looks at who benefits most from a PRP injection given within the last 48 hours.
PloemeurAges 18 years+ - NCT07607249Enrolling by invitation
Floating Needle Treatment for Stomach Issues After Knee Surgery
This trial tests whether a traditional Chinese acupuncture technique called 'floating needle' can help with stomach and bowel problems that sometimes happen after knee surgery under general anesthesia. You would receive this treatment along with standard post-surgery care to see if it reduces nausea, constipation, or other digestive issues.
Guangzhou, GuangdongAges 18 years+ - NCT06074783RecruitingPhase 1/Phase 2
Stem cell therapy for muscle and joint injuries
This study tests a new therapy made from donor stem cells that may help repair damaged muscles, bones, tendons, and joints. It is for people whose injuries or degenerative conditions have not healed on their own.
Nassau, The BahamasAges 18 years+ - NCT07502924Recruiting
Testing Geranylgeraniol supplements for muscle health
This study tests whether taking a supplement called geranylgeraniol (GG) can improve muscle health. It is looking for physically active adults who are willing to follow specific dietary rules and avoid certain foods and supplements during the study.
Saint Charles, MissouriAges 30–60 - NCT03286868Recruiting
Tested knee replacement alignment during knee surgery
This study looks at how a specific computer/measurement approach (“Verasense”) helps position the knee during total knee replacement for people with knee arthritis. It may help improve how the new knee fits and aligns as you recover.
Halifax, Nova ScotiaAges 21–80 - NCT05942430Recruiting
Bone-cartilage transplant for ankle joint cartilage damage
This trial studies an “autologous” transplant, meaning using your own bone and cartilage, to treat painful cartilage damage in the ankle (on the talus). It may help people whose ankle cartilage injury is deep, has not improved with non-surgical care, and meets specific side and health requirements.
Guangzhou, GuangdongAges 18–60 - NCT06662955Recruiting
Exercise with sound cues after ACL reconstruction
This study tests if adding sounds (like a metronome beat) to your rehab exercises helps your leg muscles work better after ACL reconstruction. It is for athletes who had their ACL surgery within the past 2 weeks and are ready to start moving.
Salaya, Changwat Nakhon PathomAges 18–35 - NCT07599865RecruitingPhase 2
Bubble study for knee infection after joint replacement
This trial tests if a contrast agent used in ultrasound can help surgeons see pockets of infection around knee implants during revision surgery. It may help doctors do a better job cleaning out the infection.
Philadelphia, PennsylvaniaAges 18 years+ - NCT06666829Recruiting
Personalized rehab with robotics for kids with developmental disabilities
This trial tests a personalized rehabilitation plan that uses new technology and robotic devices to help children and teens with developmental disabilities. The goal is to see if combining these tools can improve daily skills and quality of life.
Genova, GenovaAges 5–21 - NCT06667739Recruiting
Promoting physical activity after leg amputation
This study tests a program to help people who have lost a leg due to diabetes or blood vessel disease become more active. It uses coaching and online modules to support your progress.
Toronto, OntarioAges 18 years+ - NCT06773000Recruiting
Nutritional supplement study for hip fracture recovery in older adults
This trial tests whether a nutritional supplement can help older adults recover better after hip fracture surgery. It may improve strength and healing during the recovery period.
New York, New YorkAges 65 years+
Common questions
- How many bones, joints & muscles clinical trials are recruiting?
- Clin2 is tracking 4,841 recruiting rheumatology & orthopedics studies from the U.S. registry right now, out of 7,937 we cover in this area in total.
- What does “Bones, joints & muscles” cover here?
- Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We group each study into bones, joints & muscles based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a bones, joints & muscles trial near me?
- Use the search to filter bones, joints & muscles studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.