Rheumatology & orthopedics
Bones, joints & muscles clinical trials
Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We’re tracking 4,611 recruiting studies in this area right now.
By phase
- Not applicable3,768
- Phase 2217
- Phase 4200
- Phase 1182
- Phase 3139
- Phase 1/Phase 271
- Phase 2/Phase 334
Top conditions
- Knee Osteoarthritis172
- Rheumatoid Arthritis132
- Fibromyalgia105
- Osteoporosis82
- Osteoarthritis71
- Rheumatoid Arthritis (RA)68
- Osteoarthritis, Knee64
- Shoulder Pain48
- Hip Osteoarthritis43
- Psoriatic Arthritis40
- Degenerative Disc Disease39
- Chronic Pain38
- Total Knee Arthroplasty38
- Duchenne Muscular Dystrophy37
- Systemic Lupus Erythematosus37
- Musculoskeletal Pain35
- Osteoarthritis (OA) of the Knee32
- Pain32
Leading sponsors
- Riphah International University85
- Istituto Ortopedico Rizzoli69
- Cairo University65
- Assistance Publique - Hôpitaux de Paris36
- Foundation University Islamabad31
- Mayo Clinic28
- Massachusetts General Hospital25
- National Taiwan University Hospital25
- Hacettepe University23
- Tanta University22
Where studies are running
- California207
- New York87
- Florida82
- Maryland76
- Arizona72
- Massachusetts71
- Texas67
- Alabama59
- Illinois51
- Pennsylvania48
Recruiting studies4,611 total
- NCT07662993Enrolling by invitation
Cognitive skills in fibromyalgia study
This study looks at how fibromyalgia affects thinking skills like memory and focus. It aims to understand which factors are linked to these cognitive changes in women with fibromyalgia.
DenizliAges 18–65 - NCT07662408RecruitingPhase 4
Comparing two drugs to prevent low blood pressure during hip surgery
This trial tests two different medicines (norepinephrine and phenylephrine) given as an infusion to prevent low blood pressure after spinal anesthesia for hip surgery. It may help older adults undergoing planned hip replacement or repair.
SohagAges 60–100 - NCT07660523Recruiting
Shockwave therapy for neck and shoulder muscle pain
This trial tests if focused shockwave therapy can help people with long-term neck and shoulder pain caused by tight muscles in the upper back. The goal is to see if this treatment is safe and effective for easing pain and improving daily activities.
Kaohsiung CityAges 20 years+ - NCT07662239Recruiting
Exercise program for young sarcoma survivors
This study tests a personalized exercise service for teenagers and young adults who have had sarcoma. It aims to help you get active and stay healthy after treatment.
Boston, MassachusettsAges 15–39 - NCT05809622Recruiting
Arm and elbow exercises for a sore tennis elbow
This study compares two exercise programs to see which helps people with long-lasting pain on one elbow (tennis elbow). If you have symptoms for at least 3 months, the trial may help improve pain and function using supervised, elbow-focused training.
IstanbulAges 18–65 - NCT05733377Recruiting
Non-invasive scans to study back curve during pregnancy
This trial uses a non-invasive imaging scan to measure a common back curvature called lordosis during pregnancy. Researchers will look at how these measurements relate to birth outcomes in low-risk pregnancies.
Alcalá de Henares, MadridAges 20–40 - NCT06171204Recruiting
Knee arthritis treatment with your own cells
This trial tests a treatment using your own cells (stromal vascular fraction) to repair knee joint damage and reduce pain. It may help people with knee arthritis, tendon injuries, or persistent knee pain.
Ghent, Oost-VlaanderenAges 18–90 - NCT06603831Recruiting
3D digital surgery study for bone and joint procedures
This study tests whether 3D digital planning tools make surgeries for certain bone and joint problems more effective and cost-efficient. If you need a specific type of surgery on your forearm, pelvis, or spine, this trial could help determine if digital surgery improves your recovery.
Sabadell, BarcelonaAges 18–80 - NCT02915120Recruiting
Ultrasound-guided nerve treatment for knee osteoarthritis pain
This trial studies whether a targeted, ultrasound-guided “pulsed” radiofrequency treatment can reduce long-lasting knee pain from osteoarthritis. It may help if your knee pain is not improving with common medicines and injections.
Palma, Balear IslandsAges 40 years+ - NCT06451562Recruiting
Pain relief methods after scoliosis surgery
This trial compares two ways to manage pain after scoliosis surgery: numbing the area near the spine (regional anesthesia) or giving lidocaine through an IV. The goal is to see which method reduces the need for morphine after surgery.
Be’er Ya‘aqovAges 12–25 - NCT06671665Recruiting
Manual therapy for low back pain in women with osteopenia
This study tests if manual therapy (hands-on treatment by a therapist) can reduce low back pain in postmenopausal women who have osteopenia, a condition where bones are weaker than normal but not yet osteoporosis. It aims to help with pain located in the lower back area.
GizaAges 50–60 - NCT07651306Recruiting
Bone Loss After Stroke: New X-ray Detection Method
This study tests whether a new way of measuring X-rays can detect bone loss in the shoulder after a stroke. The research may help doctors identify patients at risk for fractures earlier.
IstanbulAges 18 years+ - NCT07652372Enrolling by invitationPhase 1
Injectable RAB001 for knee osteoarthritis (Phase 1b)
This trial tests an injectable medication called RAB001 for people with knee osteoarthritis that hasn't improved with other treatments. The goal is to see if it's safe and helps reduce pain.
Beijin, BeijinAges 40–75 - NCT07651735Recruiting
Safety and Recovery Study of Tipmed Hip Replacement
This study tracks how well people recover after hip replacement surgery using the Tipmed hip implant system. Researchers will monitor your healing and implant performance over time to ensure the device works safely and effectively.
BalıkesirAges 18 years+ - NCT07654751RecruitingPhase 4
Study of Tremfya in breast milk of breastfeeding women
This study measures how much Tremfya (guselkumab) gets into breast milk for women who are already taking it for conditions like psoriasis or arthritis and choose to breastfeed. It helps understand if the drug passes to the baby.
Chapel Hill, North CarolinaAges 18 years+ - NCT07653295Recruiting
Study of Tıpmed revision hip replacement safety
This study follows patients who already had a revision hip replacement using the Tıpmed system. Researchers want to confirm the implant is safe and works well over time.
BalıkesirAges 18 years+ - NCT07646782Recruiting
Human Observatory Study: Aging and Longevity Research
This study observes how people age over time to better understand what helps people live longer and healthier lives. You'll share health information through surveys or online screening, and researchers will track changes in your health and wellbeing.
Boulder, ColoradoAges 18 years+ - NCT07649265RecruitingPhase 1
Testing a new drug for autoimmune diseases
This study tests a new drug called HBM7020 to see if it is safe and how well it is absorbed by the body. It is for healthy people and people with certain autoimmune diseases like lupus, scleroderma, rheumatoid arthritis, or Sjögren's disease.
Brisbane, QueenslandAges 18–75 - NCT07647354Recruiting
Mako robotic joint replacement surgery registry study
This study collects information from patients undergoing hip or knee replacement surgery with either traditional or robotic-assisted techniques. Researchers track your recovery and joint function to understand how well these procedures work.
Jacksonville, FloridaAges 18 years+ - NCT06686524RecruitingPhase 1
CD19-targeted UCAR-T for refractory juvenile dermatomyositis
This trial tests a new type of immune cell therapy (UCAR-T) that targets a protein called CD19 to treat children with a severe form of juvenile dermatomyositis that hasn't responded to standard treatments. It aims to calm the overactive immune system and reduce symptoms like muscle weakness and skin rashes.
Hangzhou, ZhejiangAges 5 years+ - NCT07651215Enrolling by invitation
Short-Stem Shoulder Replacement Surgery Outcomes Study
This study looks at how well a newer type of shoulder replacement surgery works. Researchers are checking X-rays and patient function for people who had this specific short-stem surgery at least 2 years ago.
LinzAges 18 years+ - NCT07649356Recruiting
Estrogen and Muscle Function in Menopausal Women
This study compares how estrogen affects muscle strength and fitness in women before and after menopause. It aims to understand how hormonal changes during menopause impact physical health and may help researchers develop better support for women during this life stage.
AarhusAges 47 years+ - NCT07650396RecruitingPhase 3
Steroid Injections for Long-Term Achilles Tendon Pain
This study tests whether steroid injections can help people with chronic Achilles tendon pain (the tendon at the back of your heel) who haven't improved with physical therapy and exercise. The injection is designed to reduce inflammation and pain in the middle part of the tendon.
RotterdamAges 18–65 - NCT07653828Recruiting
Self-rehab after foot surgery via app
This trial tests if using a connected app to do self-guided rehab at home helps people recover better after bunion (hallux valgus) surgery. It may offer a convenient way to follow your exercises and track progress.
Saint-JeanAges 18–85
Common questions
- How many bones, joints & muscles clinical trials are recruiting?
- Clin2 is tracking 4,611 recruiting rheumatology & orthopedics studies from the U.S. registry right now, out of 7,492 we cover in this area in total.
- What does “Bones, joints & muscles” cover here?
- Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We group each study into bones, joints & muscles based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a bones, joints & muscles trial near me?
- Use the search to filter bones, joints & muscles studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.