Rheumatology & orthopedics
Bones, joints & muscles clinical trials
Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We’re tracking 4,611 recruiting studies in this area right now.
By phase
- Not applicable3,768
- Phase 2217
- Phase 4200
- Phase 1182
- Phase 3139
- Phase 1/Phase 271
- Phase 2/Phase 334
Top conditions
- Knee Osteoarthritis172
- Rheumatoid Arthritis132
- Fibromyalgia105
- Osteoporosis82
- Osteoarthritis71
- Rheumatoid Arthritis (RA)68
- Osteoarthritis, Knee64
- Shoulder Pain48
- Hip Osteoarthritis43
- Psoriatic Arthritis40
- Degenerative Disc Disease39
- Chronic Pain38
- Total Knee Arthroplasty38
- Duchenne Muscular Dystrophy37
- Systemic Lupus Erythematosus37
- Musculoskeletal Pain35
- Osteoarthritis (OA) of the Knee32
- Pain32
Leading sponsors
- Riphah International University85
- Istituto Ortopedico Rizzoli69
- Cairo University65
- Assistance Publique - Hôpitaux de Paris36
- Foundation University Islamabad31
- Mayo Clinic28
- Massachusetts General Hospital25
- National Taiwan University Hospital25
- Hacettepe University23
- Tanta University22
Where studies are running
- California207
- New York87
- Florida82
- Maryland76
- Arizona72
- Massachusetts71
- Texas67
- Alabama59
- Illinois51
- Pennsylvania48
Recruiting studies4,611 total
- NCT07626632Recruiting
Tyler Twist vs. Eccentric Exercises for Tennis Elbow
This study compares two exercise approaches for treating lateral epicondylitis (tennis elbow) in people aged 20–40. It tests whether a specific twisting exercise called the Tyler Twist works better than eccentric exercises (where you lengthen a muscle under tension) to reduce pain and improve grip strength.
Lahore, Punjab ProvinceAges 20–40 - NCT07620834Recruiting
AI-Guided Bone Density Screening for High-Risk Adults
This study tests whether artificial intelligence can help identify people at risk for weak bones (osteoporosis) using chest X-rays. If you qualify, you'll be randomly assigned to either standard screening or AI-enhanced screening to see which approach works better.
ChanghuaAges 40–80 - NCT07629141Recruiting
Muscle Position and Dry Needling for Neck Pain
This study tests whether the position of your neck muscle affects how well dry needling (inserting thin needles into tight muscle knots) relieves chronic neck pain. Dry needling may help reduce pain by relaxing tense muscles.
Alcalá de Henares, MadridAges 18–80 - NCT07623408Recruiting
Foot Position During Achilles Tendon Pain Recovery
This study tests whether the position of your foot during exercises affects how well your Achilles tendon heals and how much pain you experience. Researchers will compare different foot positions during rehabilitation to see which works best for reducing Achilles tendon pain and improving tendon strength.
Leuven, Vlaams-BrabantAges 18–65 - NCT07627854Recruiting
Cold therapy after knee replacement surgery
This study compares two ways to reduce pain and swelling after total knee replacement: a special cold wrap (cryocuff) versus a standard ice pack. You'll help researchers understand which method works better for your recovery.
Kremmen, BrandenburgAges 18 years+ - NCT07627542Recruiting
Smartphone use and neck posture in arthritis patients
This study looks at how much time people with rheumatoid arthritis or ankylosing spondylitis spend on smartphones and how it affects their neck posture, balance, and disability. Understanding this connection may help doctors give better advice about phone use and neck health.
Konya, MeramAges 18–65 - NCT07628335Recruiting
Gong's Mobilization Techniques for Frozen Shoulder
This trial tests whether a specific hands-on physical therapy technique called Gong's mobilization, with or without an additional method called Nielasher, can help restore movement and reduce pain in frozen shoulder. Frozen shoulder is a condition where the shoulder becomes stiff and painful, limiting your ability to move your arm.
Lahore, Punjab ProvinceAges 40–60 - NCT07628413Recruiting
Exercise Methods for Neck and Shoulder Pain
This study compares two types of gentle exercise programs—Egoscue and Feldenkrais—to help people with chronic neck pain and poor posture. Both programs focus on retraining muscles and improving how your body moves, and the study will measure which approach works better.
Lahore, Punjab ProvinceAges 25–45 - NCT07626619Recruiting
Urdu translation of a muscle and nerve assessment tool
This study is testing a translated version of a tool that measures how well muscles and nerves work. Researchers want to make sure the Urdu translation works correctly for Pakistani patients and healthy volunteers.
Lahore, Punjab ProvinceAges 20–45 - NCT07623304Recruiting
Exercise guidance system after spinal fusion surgery
This study tests a computer system that guides exercise recovery after spine surgery. It aims to help you heal better and move more safely at home using your WiFi connection.
Nantong, JiangsuAges 18–65 - NCT07624136Recruiting
Kinesio Taping for Shoulder Flexibility and Range of Motion
This study tests whether a special athletic tape (Kinesio tape) applied to your lower back and shoulder area can improve flexibility and reduce shoulder pain in people with chronic shoulder impingement syndrome—a condition where shoulder structures get pinched, causing long-term pain and stiffness.
Ankara, AltindagAges 20–40 - NCT07621679Recruiting
Walking Program to Prevent Falls and Fractures in Older Adults
This study tests whether a specialized walking and balance program helps people aged 70+ with weak bones reduce their risk of falls and fractures. The program is designed to improve strength, balance, and confidence in daily movement.
Montreal, QuebecAges 70 years+ - NCT07624474Recruiting
Testing an elbow injury score for French-speaking children
This study is testing a French translation of a scoring system that measures how well children's elbows are working after injury. Researchers want to make sure this tool accurately reflects how kids actually function.
AmiensAges 4–17 - NCT07627308Recruiting
Ultrasound vs Fluoroscopy for Nerve Injections in Back Pain
This trial compares two imaging methods—ultrasound and fluoroscopy (X-ray)—to guide nerve injections for leg pain caused by compressed nerves in the lower back. The goal is to see which method is safer and more effective at relieving your pain.
Tanta, Gharbia GovernorateAges 18–75 - NCT07626346Recruiting
Pain relief medication added to shoulder surgery nerve block
This trial tests whether adding a medication called dexmedetomidine to a numbing injection around shoulder nerves can improve pain control after laparoscopic shoulder surgery. The goal is to see if this combination works better than the numbing medication alone.
CairoAges 18–65 - NCT02398786Recruiting
Join a family registry for myotonic dystrophy (DM1 or DM2)
This study builds a registry of people and families affected by myotonic dystrophy types 1 and 2. It helps researchers learn about the condition over time and may support future studies that could lead to better care.
Oakland, CaliforniaAges Any age - NCT06000956RecruitingPhase 3
Jitongning tablets for active spondyloarthritis
This trial tests a Chinese herbal tablet called Jitongning against a placebo to see if it can improve overall symptoms in people with active axial osteoarthritis. You may be eligible if your arthritis is active, you have a specific genetic marker (HLA-B27 positive), and your inflammation levels are high.
Beijing, Beijing MunicipalityAges 18–65 - NCT06492148Recruiting
Myofascial Release for Period Pain in Women
This study tests a gentle hands-on technique called myofascial release to see if it can reduce period pain in women who have primary dysmenorrhea (painful periods without an underlying condition). If you have moderate to severe cramps and don't use hormonal birth control, you may be able to join.
AnkaraAges 18–35 - NCT06500390Recruiting
TMD and levonorgestrel IUD use study
This study looks at whether using a levonorgestrel intrauterine device (a hormone-releasing IUD) for at least 3 months is linked to jaw joint problems (temporomandibular disorder). It may help women understand potential side effects of this birth control method.
Istanbul, MaltepeAges 18–45 - NCT07615049RecruitingPhase 3
Shorter versus standard radiation for soft tissue sarcoma
This trial compares a shorter course of radiation therapy with the standard longer course for people with soft tissue sarcoma in an arm or leg. The goal is to see if the shorter course works just as well and may be more convenient.
Birmingham, AlabamaAges 18 years+ - NCT07614555Recruiting
Breathing methods during back surgery recovery
This study compares two ways doctors control your breathing during lumbar disc herniation (slipped disc) surgery. Researchers want to see which method keeps your lungs healthier during the operation.
AnkaraAges 18–65 - NCT06112665RecruitingPhase 4
Tofacitinib for early active axial spondyloarthritis
This trial tests whether tofacitinib (a pill that reduces inflammation) can help people with early-stage axial spondyloarthritis, a type of arthritis that mainly affects the spine and pelvis. It's for those who have had symptoms for 2 years or less and have active disease with signs of inflammation in MRI or blood tests.
BerlinAges 18–45 - NCT06632639Recruiting
Wedged insoles with ankle straps for knee pain and bow legs
This trial tests whether special shoe inserts (wedged insoles) combined with ankle straps can reduce pain and improve knee alignment in people with mild bow legs and inner knee pain. It aims to help those who have not had knee surgery and can walk without help.
GizaAges 20–60 - NCT07615322Recruiting
Smartphone Use, Posture, and Breathing in College Students
This study explores how smartphone addiction affects posture and breathing in young adults. Researchers will measure your posture, breathing patterns, and smartphone habits to understand if heavy phone use changes how you stand and breathe.
Maltepe, IstanbulAges 18–35
Common questions
- How many bones, joints & muscles clinical trials are recruiting?
- Clin2 is tracking 4,611 recruiting rheumatology & orthopedics studies from the U.S. registry right now, out of 7,492 we cover in this area in total.
- What does “Bones, joints & muscles” cover here?
- Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We group each study into bones, joints & muscles based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a bones, joints & muscles trial near me?
- Use the search to filter bones, joints & muscles studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.