Rheumatology & orthopedics
Bones, joints & muscles clinical trials
Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We’re tracking 4,610 recruiting studies in this area right now.
By phase
- Not applicable3,773
- Phase 2214
- Phase 4199
- Phase 1182
- Phase 3138
- Phase 1/Phase 270
- Phase 2/Phase 334
Top conditions
- Knee Osteoarthritis173
- Rheumatoid Arthritis131
- Fibromyalgia104
- Osteoporosis82
- Osteoarthritis71
- Rheumatoid Arthritis (RA)68
- Osteoarthritis, Knee65
- Shoulder Pain48
- Hip Osteoarthritis43
- Degenerative Disc Disease39
- Psoriatic Arthritis39
- Chronic Pain38
- Total Knee Arthroplasty38
- Systemic Lupus Erythematosus37
- Duchenne Muscular Dystrophy36
- Musculoskeletal Pain35
- Osteoarthritis (OA) of the Knee32
- Pain32
Leading sponsors
- Riphah International University85
- Istituto Ortopedico Rizzoli69
- Cairo University65
- Assistance Publique - Hôpitaux de Paris36
- Foundation University Islamabad31
- Mayo Clinic28
- Massachusetts General Hospital25
- National Taiwan University Hospital24
- Hacettepe University23
- Tanta University22
Where studies are running
- California206
- New York86
- Florida83
- Maryland76
- Arizona71
- Massachusetts71
- Texas66
- Alabama60
- Illinois50
- Pennsylvania47
Recruiting studies4,610 total
- NCT07308873Recruiting
Gait and knee osteoarthritis pain study
This study looks at how walking patterns relate to knee pain from osteoarthritis. It aims to understand individual differences to improve future treatments.
Pittsburgh, PennsylvaniaAges 45–80 - NCT07314099Recruiting
Study of the Breizh Fabribus program for assistive devices
This study looks at the Breizh Fabribus program, which helps people get personalized assistive devices. It aims to see if the program helps improve your daily life.
Brest, FinistèreAges Any age - NCT07313215Recruiting
Study of rifampin combo therapy for staph joint infections
This study tests whether adding rifampin to standard antibiotics works better for people with a staph infection in a joint replacement. It aims to find a more effective treatment for this type of infection.
Fuzhou, FujianAges 18–80 - NCT07309796Recruiting
Strengthening exercises after reverse shoulder replacement
This study tests whether specific strengthening exercises for the shoulder muscles that help lift your arm can improve recovery after a reverse total shoulder replacement. You will be randomly assigned to receive these exercises or standard care, and your progress will be tracked.
KırşehirAges 65–90 - NCT07307495Recruiting
Pain relief after back surgery and its effect on recovery
This study tests a new painkiller, oliceridine fumarate, given through a pump after lumbar spine surgery. The goal is to see if it helps the bowels and stomach recover faster compared to standard pain relief.
Xi'an, ShaanxiAges 18–75 - NCT07314840Recruiting
Ultrasound study for extra tendon spots in tennis elbow
This study uses ultrasound to check for extra inflammation spots in people with tennis elbow (lateral epicondylitis). It may help clarify why some people have ongoing elbow pain.
Istanbul, MaltepeAges 18–60 - NCT07313449Recruiting
Knee replacement study: 1-year results for a specific prosthesis
This study looks at how well a certain type of cemented total knee replacement works after at least one year. It may help doctors understand long-term outcomes for this specific knee implant.
StrasbourgAges 18 years+ - NCT07307950Recruiting
Testing an app to improve rehab for kids with movement disabilities
This study tests a new app designed to help families and therapists coordinate care for children with movement disabilities. It aims to make rehabilitation easier and more connected across different care settings.
BrestAges 2–25 - NCT07310849Recruiting
Digital health support for older adults with diabetes
This study tests a digital care program using the LINE messaging app to help older adults with diabetes and other chronic conditions manage their health. It may be a good fit if you are 50 or older, have type 2 diabetes plus another condition like high blood pressure, and are comfortable using a smartphone.
New Taipei City, Wugu DistrictAges 50 years+ - NCT07312981Recruiting
Diet tracking study for advanced kidney disease
This study compares different ways to record what you eat and drink for people with advanced kidney disease. It may help find easier methods for dietary tracking.
Herlev, Capital RegionAges 18 years+ - NCT07309003Recruiting
Electrical stimulation and exercise for knee osteoarthritis
This study tests whether a special electrical stimulation (called FES) combined with exercise can help strengthen the muscles around your knee. It may reduce pain and improve function for people with moderate knee osteoarthritis.
Ankara, AnkaraAges 50–65 - NCT07313020Enrolling by invitationEarly Phase 1
Handheld imaging to track stem cells in knee osteoarthritis
This trial tests a new handheld imaging device (MPI) to track stem cells injected into the knee. It aims to see if the device can safely monitor how the stem cells move and work in people with knee osteoarthritis.
Haikou, HainanAges 18–75 - NCT06875804Recruiting
Compressive release for knee cap tracking in knee pain
This trial tests a hands-on therapy called compressive myofascial release for the muscle on the outside of your thigh. It aims to see if it helps with kneecap tracking problems that cause pain during daily activities.
Lahore, Punjab ProvinceAges 20–40 - NCT06875817Recruiting
Feldenkrais exercises for knee osteoarthritis pain
This study tests if gentle, slow Feldenkrais movement exercises can reduce knee pain and improve mobility in people with moderate knee osteoarthritis. It is designed for those who are still able to walk and get up from the floor, but are experiencing significant pain.
Lahore, Punjab ProvinceAges 40–60 - NCT06874608Recruiting
Does an exclusion diet help juvenile arthritis?
This study tests if removing certain foods can improve arthritis symptoms in children aged 6 to 17. It may be an option if current medicines are not working well or if you want to explore dietary changes.
FlorenceAges 6–18 - NCT07301463Recruiting
Study of a new drug for children with achondroplasia
This trial tests a new medicine for children with achondroplasia (a common form of dwarfism). It aims to see if the drug can improve growth. The study is for children aged 2.5 to under 11 years old who have not started puberty and can walk without help.
Beijing, Beijing MunicipalityAges 2.5 years–11 years - NCT07301749Recruiting
Study of VCFix device for spine fractures
This trial tests a new device called VCFix to treat a single broken vertebra in the mid-to-lower back. It aims to see if the device is safe and effective for relieving pain and restoring spine function.
ChambéryAges 21–85 - NCT06793982RecruitingPhase 4
PRP vs Corticosteroids for Hip Osteoarthritis Pain
This study compares two types of hip injections—platelet-rich plasma (PRP) and corticosteroids—to see which works better for hip osteoarthritis pain. It may help you if you are considering an injection for your hip pain.
Baltimore, MarylandAges 21–80 - NCT07300384Recruiting
Blood flow restriction training for knee pain relief before surgery
This study tests whether a special type of strength training (called blood flow restriction training) can reduce pain in people with severe knee arthritis who are waiting for knee replacement surgery. The training uses a cuff on the thigh to lightly restrict blood flow while doing exercises until failure.
Valencia, ValenciaAges 50–85 - NCT07301918Recruiting
Comparing two expanders for crossbite in children
This trial compares two types of expanders (Leaf Expander vs. Hyrax Expander) to fix crossbites in children who still have some baby teeth. The goal is to see which device works better and is more comfortable.
CairoAges 6–12 - NCT07302204Recruiting
Exercise for knee osteoarthritis pain relief
This study compares two types of exercise — aerobic (like walking or cycling) versus specific therapeutic exercises — to see which one better helps people with knee osteoarthritis who do not get pain relief from exercise. It aims to find an exercise plan that reduces knee pain and improves movement.
São PauloAges 40–75 - NCT07304167Recruiting
Exercise video game program for women with fibromyalgia
This study tests whether playing a special exercise video game can help women with fibromyalgia feel better. You will be asked to play the game regularly and report how you feel.
IstanbulAges 30–70 - NCT07302074Recruiting
Comparing Rare vs. Common Inflammatory Arthritis
This study compares rare inflammatory arthritis (from rare autoimmune diseases or drugs) to more common types (like rheumatoid arthritis). Researchers will look at tissue samples to understand the differences and help improve diagnosis and treatment.
BordeauxAges 18 years+ - NCT07297459Enrolling by invitation
Surgery options for a jaw joint problem
This trial compares two types of surgery to treat a common jaw joint problem where the disc slips out of place. It looks at which procedure works better for reducing pain and improving function.
StockholmAges 18 years+
Common questions
- How many bones, joints & muscles clinical trials are recruiting?
- Clin2 is tracking 4,610 recruiting rheumatology & orthopedics studies from the U.S. registry right now, out of 7,529 we cover in this area in total.
- What does “Bones, joints & muscles” cover here?
- Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We group each study into bones, joints & muscles based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a bones, joints & muscles trial near me?
- Use the search to filter bones, joints & muscles studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.