Rheumatology & orthopedics
Bones, joints & muscles clinical trials
Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We’re tracking 4,837 recruiting studies in this area right now.
By phase
- Not applicable3,970
- Phase 2223
- Phase 4196
- Phase 1191
- Phase 3149
- Phase 1/Phase 275
- Phase 2/Phase 333
Top conditions
- Knee Osteoarthritis185
- Rheumatoid Arthritis142
- Fibromyalgia102
- Osteoporosis88
- Osteoarthritis74
- Osteoarthritis, Knee72
- Rheumatoid Arthritis (RA)65
- Shoulder Pain50
- Psoriatic Arthritis47
- Hip Osteoarthritis41
- Systemic Lupus Erythematosus41
- Duchenne Muscular Dystrophy39
- Degenerative Disc Disease38
- Total Knee Arthroplasty38
- Chronic Pain37
- Musculoskeletal Pain36
- Pain35
- Dermatomyositis31
Leading sponsors
- Riphah International University110
- Cairo University72
- Istituto Ortopedico Rizzoli71
- Assistance Publique - Hôpitaux de Paris37
- Foundation University Islamabad34
- Mayo Clinic29
- Massachusetts General Hospital27
- National Taiwan University Hospital25
- Chinese University of Hong Kong22
- Hacettepe University22
Where studies are running
- California211
- New York94
- Florida80
- Massachusetts76
- Arizona75
- Maryland73
- Texas65
- Alabama57
- Illinois54
- Pennsylvania50
Recruiting studies4,837 total
- NCT07481864Recruiting
Early mental exercise after shoulder tendon repair
This study tests if a gentle, early mental exercise program helps improve shoulder recovery after a specific type of rotator cuff repair. It might be a good fit if you had surgery on two front shoulder tendons and are otherwise healthy.
Istanbul, TurkeyAges 30–65 - NCT07583056Recruiting
Brain Stimulation Treatment for Fibromyalgia Pain
This study tests whether a non-invasive brain stimulation treatment called tDCS (transcranial direct current stimulation) can help reduce fibromyalgia pain. You'll use a small device at home that sends mild electrical currents to your scalp, and researchers will monitor your progress via video calls.
ValenciaAges 18 years+ - NCT02958020Recruiting
Osteoporosis study for adults age 45 to 79
This study collects health information to learn more about osteoporosis and who is most at risk. It may help researchers better understand prevention and early detection, based on your survey responses and basic health details.
Shenzhen, GuangdongAges 45–79 - NCT02966886Recruiting
Shoulder replacement techniques for advanced shoulder arthritis
This study compares different surgical techniques during shoulder replacement for people with advanced shoulder (glenohumeral) arthritis. It may help surgeons choose the approach that best restores function and reduces pain.
Ottawa, OntarioAges 18 years+ - NCT02979951Recruiting
IV fosfomycin for serious bacterial infections
This trial studies whether IV (through a vein) fosfomycin can treat severe bacterial infections in adults. It may help people whose infection is covered by the standard fosfomycin use and who need hospital-level care.
Hall in TirolAges 18 years+ - NCT02991469RecruitingPhase 2
Testing sarilumab for children with systemic juvenile arthritis
This trial studies sarilumab, a targeted medicine, to help reduce symptoms in children and teens with systemic juvenile idiopathic arthritis (sJIA) who have not responded enough to current treatments. You may be considered because the study looks at how well and safely repeated doses work in pediatric patients.
San Miguel de Tucumán, Tucumán ProvinceAges 1–17 - NCT03001180Recruiting
Study blood and tissue markers in vascular anomalies
This study collects extra blood (and sometimes tissue during procedures) to look for markers that can help doctors better understand vascular anomalies. It may not be a treatment, but it can improve future care by finding patterns linked to the condition.
Boston, MassachusettsAges 1 day+ - NCT03003572Recruiting
Test an immune marker in primary Sjögren’s disease activity
This study looks at an immune reaction (called anti-Ro/SSA IgE) to see how active primary Sjögren’s disease is. It may help doctors better understand what’s driving symptoms and activity levels over time.
BourgoinAges 18 years+ - NCT03017755Recruiting
Survey to help choose treatment for scoliosis
This study uses a survey to help doctors decide on the best treatment for people who have already been treated for adolescent idiopathic scoliosis. It may help improve how treatment choices are made in the future.
Rochester, MinnesotaAges 13 years+ - NCT03047369Recruiting
Myelin brain disorder research biobank for samples and data
This study collects brain-related medical information and biological samples to help researchers better understand leukodystrophies and other white-matter brain disorders. It may help future diagnosis and treatments by building a valuable “biobank” of patient data and samples.
Los Angeles, CaliforniaAges Any age - NCT03048201Recruiting
Total Knee Replacement Registry Study for a Specific Knee Implant
This study tracks outcomes for people getting a total knee replacement using a specific knee implant system. It may help doctors understand which patients do best and how the implant performs over time.
Rancho Mirage, CaliforniaAges 22 years+ - NCT03050268Recruiting
Study of childhood cancer risk in families
This study looks at inherited (family) risk for childhood cancers, including families with early cancers or known cancer risk conditions. It may help researchers understand why some children get cancer and improve future risk detection and care.
Memphis, TennesseeAges Any age - NCT03058185Recruiting
Study of people with LMNA or EMD gene mutations
This study follows people who have a confirmed harmful (pathogenic) mutation in the LMNA and/or EMD gene. It aims to better understand these conditions through regular follow-up and health information collection, which may help improve future care.
Angers, AngersAges Any age - NCT03076658Recruiting
Standing full-body X-rays from healthy adults
This trial is building a database of full-body standing X-rays in people who do not have spine problems or certain health conditions. If you qualify, your X-rays may help researchers study normal body alignment for future medical use.
Aurora, ColoradoAges 21–85 - NCT03092180Recruiting
Tests a treatment approach for certain muscle inflammation diseases
This trial looks at treatment strategies for people with idiopathic inflammatory myopathies, which are illnesses where the immune system attacks muscles. It may help improve how treatment is chosen and optimized for this group of conditions, but it specifically excludes several related muscle diseases.
São PauloAges 18 years+ - NCT03096197Recruiting
Exoskeleton and spinal stimulation for long-term spinal cord injury
This trial tests whether an external walking-assist device (an exoskeleton) plus targeted spinal cord stimulation can help people with long-term spinal cord injury. It may be designed for wheelchair users who meet specific nerve function and bone health requirements.
West Orange, New JerseyAges 18–65 - NCT03093909RecruitingPhase 1
Breathing treatment with gemcitabine for lung cancer spread
This early-stage trial studies an inhaled (aerosol) form of gemcitabine to treat solid tumors that have spread to the lungs. It aims to see whether this lung-focused treatment is safe and how well it might work when standard curative options are not available.
Houston, TexasAges 12–50 - NCT03107520RecruitingEarly Phase 1
Ultrasound during hip surgery to check blood flow
This early-phase study tests a special ultrasound with an added contrast medicine (Lumason) during surgery for babies with developmental dysplasia of the hip (DDH). It aims to better see blood flow at the time of surgery, which may help guide and improve care.
Philadelphia, PennsylvaniaAges 4 months–2 years - NCT03107533Recruiting
Shared decision support for moderate scoliosis
This study tests a shared decision-making approach to help people with scoliosis make treatment choices together with their care team. It may help ensure you understand options and feel more confident about your plan.
Rochester, MinnesotaAges 13 years+ - NCT03152617Recruiting
Study on nutrition and mouth health risks after obesity treatment
This trial looks at risks like malnutrition, weak bones, and oral (mouth) health problems after obesity treatment. It may help improve follow-up care for people who receive specialist treatment or weight-loss surgery.
GothenburgAges 18 years+ - NCT03160274Recruiting
Genetic testing for certain adrenal and nerve tumors
This study looks at genetic (DNA) changes in people with pheochromocytoma or paraganglioma and related conditions. It may help clarify why these conditions happen and how they run in families.
San Antonio, TexasAges Any age - NCT03158090Recruiting
Study of treatment patterns for acromegaly over time
This study follows people with acromegaly to better understand how treatments are used in real life and how well they work over time. It may help improve future treatment choices by comparing outcomes across different care patterns.
Guangzhou, GuangdongAges 18–75 - NCT03181048Recruiting
Testing hip surgery plan during periacetabular osteotomy for hip dysplasia
This trial looks at whether doing hip arthroscopy at the same time as periacetabular osteotomy (PAO) is safe and helpful for people with hip dysplasia. It may matter for improving hip joint outcomes while your surgeon corrects bone alignment.
Rochester, MinnesotaAges 15–55 - NCT03184545RecruitingPhase 3
Electrical stimulation vs physical therapy for knee pain
This trial compares an electrical stimulation treatment to standard physical therapy for people with long-lasting pain in the front of the knee. It aims to see which approach better improves symptoms and function for patellofemoral pain syndrome.
New York, New YorkAges 18–40
Common questions
- How many bones, joints & muscles clinical trials are recruiting?
- Clin2 is tracking 4,837 recruiting rheumatology & orthopedics studies from the U.S. registry right now, out of 7,953 we cover in this area in total.
- What does “Bones, joints & muscles” cover here?
- Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We group each study into bones, joints & muscles based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a bones, joints & muscles trial near me?
- Use the search to filter bones, joints & muscles studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.