Rheumatology & orthopedics
Bones, joints & muscles clinical trials
Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We’re tracking 4,837 recruiting studies in this area right now.
By phase
- Not applicable3,970
- Phase 2223
- Phase 4196
- Phase 1191
- Phase 3149
- Phase 1/Phase 275
- Phase 2/Phase 333
Top conditions
- Knee Osteoarthritis185
- Rheumatoid Arthritis142
- Fibromyalgia102
- Osteoporosis88
- Osteoarthritis74
- Osteoarthritis, Knee72
- Rheumatoid Arthritis (RA)65
- Shoulder Pain50
- Psoriatic Arthritis47
- Hip Osteoarthritis41
- Systemic Lupus Erythematosus41
- Duchenne Muscular Dystrophy39
- Degenerative Disc Disease38
- Total Knee Arthroplasty38
- Chronic Pain37
- Musculoskeletal Pain36
- Pain35
- Dermatomyositis31
Leading sponsors
- Riphah International University110
- Cairo University72
- Istituto Ortopedico Rizzoli71
- Assistance Publique - Hôpitaux de Paris37
- Foundation University Islamabad34
- Mayo Clinic29
- Massachusetts General Hospital27
- National Taiwan University Hospital25
- Chinese University of Hong Kong22
- Hacettepe University22
Where studies are running
- California211
- New York94
- Florida80
- Massachusetts76
- Arizona75
- Maryland73
- Texas65
- Alabama57
- Illinois54
- Pennsylvania50
Recruiting studies4,837 total
- NCT04075539RecruitingPhase 3
At-home cycling for lumbar spinal stenosis pain
This study tests whether an at-home cycling program can reduce leg and back pain caused by lumbar spinal stenosis. It aims to see if regular, supervised cycling helps people walk and function better.
Paris, Île-de-France RegionAges 50 years+ - NCT04081896Recruiting
Rehab program for adults with spine pain
This trial studies whether a prescribed physical therapy (rehab) program helps people with spine pain. It may help by improving pain and function when a clinician has already recommended rehabilitation.
San Diego, CaliforniaAges 18–89 - NCT04084795Recruiting
EMDR plus brain stimulation for fibromyalgia pain and stress
This trial tests whether combining EMDR therapy with a mild form of brain stimulation can reduce fibromyalgia symptoms, including pain and trauma-related emotional distress. It may help people whose fibromyalgia is closely linked to past trauma and current anxiety or depression.
Barcelona, CataloniaAges 18–70 - NCT04086329RecruitingPhase 1
Testing an oxygen sensor during exercise in muscle disease
This early (Phase 1) study checks whether a tiny oxygen-sensing device works reliably while people with mitochondrial muscle disease (and some healthy volunteers) ride a stationary bike. The goal is to see if the sensor can measure oxygen use during exercise and help future monitoring or research.
Philadelphia, PennsylvaniaAges 18–65 - NCT04090359RecruitingPhase 4
Dual-mobility cups for hip replacement revision surgery
This trial studies a specific kind of hip socket (a dual-mobility cup) used during revision hip replacement surgery. It may help improve hip stability and reduce the chance of dislocation when surgeons redo or convert a previous hip implant.
New York, New YorkAges 18 years+ - NCT04102930Recruiting
Study of immune and genetic features in GCA and PMR
This study looks at immune system and genetic (inherited) differences in people diagnosed with giant cell arteritis or polymyalgia rheumatica. It aims to improve understanding of why these conditions happen and how they vary between people.
Canterbury, KentAges 50 years+ - NCT04110730Recruiting
Testing 3D-printed prostheses on hand and arm brain signals
This study looks at how 3D-printed prosthetic devices affect brain and nerve activity related to moving and using the upper limb. You might be able to join if you are a child or teen who is missing part of a hand/arm and has upper-limb movement difficulties.
Omaha, NebraskaAges 3–18 - NCT04112992Recruiting
Registry for post-injury long bone bone defects
This study is a registry that collects real-world information about adults with bone gaps in the long bones caused by injury. It may help researchers understand what treatments work best and improve care for these defects over time.
Los Angeles, CaliforniaAges 18 years+ - NCT04116723Recruiting
Flexible brace treatment for teens with scoliosis
This trial tests whether a flexible brace can help improve or control adolescent idiopathic scoliosis in teenagers whose curve is in a specific range. You may be eligible if you already tried a rigid brace and meet other physical and safety requirements.
Hong KongAges 10–15 - NCT04113759Recruiting
Blood-flow restriction therapy after hip arthroscopy
This study looks at whether limiting blood flow to the thigh after hip arthroscopy (a hip surgery to repair damage) can improve recovery. You may be able to join if you’re a young adult scheduled for first-time hip arthroscopy for certain hip problems.
Chicago, IllinoisAges 18–40 - NCT04117685Recruiting
Global hip dysplasia registry for young children
This trial is a worldwide registry that collects information from children with hip dysplasia or who are at higher risk. It helps researchers understand who is affected and how hip evaluations are done, which can improve future care.
Vancouver, British ColumbiaAges 1 minute–10 years - NCT04115774Recruiting
Registry for people with osteogenesis imperfecta
This study is a registry, meaning it collects health information about people with osteogenesis imperfecta (OI) to better understand the condition. It may help researchers learn what care works best and how OI varies from person to person.
Bologna, Emilia-RomagnaAges Any age - NCT04117841Recruiting
Registry study following children with slipped hip
This study keeps track of children diagnosed with slipped capital femoral epiphysis (SCFE) over time. It helps doctors better understand how SCFE progresses and how different treatments affect outcomes.
Vancouver, British ColumbiaAges birth–18 years - NCT04117360Recruiting
Speech therapy study for people after jaw alignment surgery
This study looks at how well people can make specific speech sounds before and after jaw alignment treatment. It may help researchers understand whether speech patterns improve with treatment in people with certain bite differences.
Chapel Hill, North CarolinaAges 15–40 - NCT04121780RecruitingPhase 2
Growth hormone treatment for retired NFL players with low hormone
This Phase 2 study tests whether growth hormone replacement helps retired professional football players who have been diagnosed with growth hormone deficiency. You may be considered if you meet age and health requirements and have the specific hormone diagnosis.
Dearborn, MichiganAges 18–76 - NCT04122313Recruiting
Radiation after surgery for Dupuytren’s hand contracture
This trial looks at using radiation after contracture-release surgery for people with Dupuytren’s disease. It may help prevent the hand tightening from coming back and improve hand function.
Minneapolis, MinnesotaAges 18 years+ - NCT04128670Recruiting
Kinesio tape test for sore muscles after exercise
This study checks whether Kinesio tape changes how sore your muscles feel after workouts. You may help researchers learn if the tape reduces “delayed onset muscle soreness” after upper-body activity.
Indianapolis, IndianaAges 18–30 - NCT04134572Recruiting
Registry for Ollier disease and Maffucci syndrome
This trial is a registry, which means it collects information about people with Ollier disease and Maffucci syndrome. It can help researchers better understand these conditions and plan future studies.
Bologna, Emilia-RomagnaAges Any age - NCT04133285Recruiting
Registry for people with multiple bone growths
This study is a registry that collects information about people with multiple osteochondromas (extra bone/cartilage growths). It may help researchers better understand the condition and improve future care, even if no treatment is given.
Bologna, Emilia-RomagnaAges Any age - NCT04137835Recruiting
Noninvasive motion testing for arm and leg function
This study tests how well your upper and lower body moves using non-invasive methods (no procedures or surgery). It’s likely best for healthy adults who can follow instructions and want to help researchers measure movement and function.
Aurora, ColoradoAges 18–65 - NCT04140344Recruiting
Study texting messages after low back fusion surgery
This study tests whether regular text-message check-ins after lumbar (low back) fusion surgery are helpful for communication and follow-up. It enrolls people who will be getting their first low back fusion and who are comfortable texting and willing to stay in regular contact.
Durham, North CarolinaAges 18 years+ - NCT04152551RecruitingPhase 4
Bisphosphonate use and hearing loss in type 1 osteogenesis imperfecta
This study looks at whether bisphosphonate treatment affects hearing loss in people with type 1 osteogenesis imperfecta. If you qualify, it may help researchers understand if treatment can protect hearing over time.
New York, New YorkAges 6–100 - NCT04153994Recruiting
Numbing injection study for kids’ scoliosis back surgery pain
This trial tests whether a specific numbing injection (placed in the muscles of the back) can improve pain control for children having one-stage scoliosis surgery. It may help reduce post-surgery pain needs and improve comfort.
Palo Alto, CaliforniaAges Up to 18 years - NCT04159675Recruiting
Burosumab and vitamin D for kids needing skull surgery
This study tests whether burosumab and vitamin D affect bone cells before and around the time of craniosynostosis surgery in children. It may help researchers understand treatment options for rare calcium and phosphate bone disorders that can affect skull growth.
BronAges 4 months–18 years
Common questions
- How many bones, joints & muscles clinical trials are recruiting?
- Clin2 is tracking 4,837 recruiting rheumatology & orthopedics studies from the U.S. registry right now, out of 7,953 we cover in this area in total.
- What does “Bones, joints & muscles” cover here?
- Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We group each study into bones, joints & muscles based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a bones, joints & muscles trial near me?
- Use the search to filter bones, joints & muscles studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.