Rheumatology & orthopedics
Bones, joints & muscles clinical trials
Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We’re tracking 4,610 recruiting studies in this area right now.
By phase
- Not applicable3,773
- Phase 2214
- Phase 4199
- Phase 1182
- Phase 3138
- Phase 1/Phase 270
- Phase 2/Phase 334
Top conditions
- Knee Osteoarthritis173
- Rheumatoid Arthritis131
- Fibromyalgia104
- Osteoporosis82
- Osteoarthritis71
- Rheumatoid Arthritis (RA)68
- Osteoarthritis, Knee65
- Shoulder Pain48
- Hip Osteoarthritis43
- Degenerative Disc Disease39
- Psoriatic Arthritis39
- Chronic Pain38
- Total Knee Arthroplasty38
- Systemic Lupus Erythematosus37
- Duchenne Muscular Dystrophy36
- Musculoskeletal Pain35
- Osteoarthritis (OA) of the Knee32
- Pain32
Leading sponsors
- Riphah International University85
- Istituto Ortopedico Rizzoli69
- Cairo University65
- Assistance Publique - Hôpitaux de Paris36
- Foundation University Islamabad31
- Mayo Clinic28
- Massachusetts General Hospital25
- National Taiwan University Hospital24
- Hacettepe University23
- Tanta University22
Where studies are running
- California206
- New York86
- Florida83
- Maryland76
- Arizona71
- Massachusetts71
- Texas66
- Alabama60
- Illinois50
- Pennsylvania47
Recruiting studies4,610 total
- NCT04228419Recruiting
Shoulder replacement approach comparison for advanced shoulder arthritis
This trial compares two ways of doing shoulder arthroplasty (shoulder replacement) for people with advanced shoulder arthritis who have not improved with non-surgical treatments. It may help determine which approach works better for pain and function.
Edmonton, AlbertaAges 65 years+ - NCT04468178Recruiting
Testing a new shoulder implant and checking its position over time
This study looks at how well a specific shoulder replacement implant works for people with worn-out (arthritic) shoulder joints. It also checks how well the implant stays in the right position as you heal after surgery.
Hanover, Lower SaxonyAges 18–80 - NCT06354543Recruiting
A study on Teknimed bone cement for joint replacement
This study is looking at how well Teknimed bone cements and cement restrictors work for people who need a joint replacement (like a hip or knee). If you are scheduled for a joint replacement or have already had one using these products since 2016, you may be able to join.
Brive-la-Gaillarde, AquitaineAges 18 years+ - NCT06641895RecruitingEarly Phase 1
Testing BBM-D101 gene therapy for Duchenne muscular dystrophy
This early-phase study tests a new gene therapy called BBM-D101 for boys with Duchenne muscular dystrophy (DMD). The goal is to see if it is safe and helps improve muscle function in young boys.
Shanghai, Shanghai MunicipalityAges 4–8 - NCT06843798Recruiting
Healthcare workers' ergonomic knowledge and muscle pain
This study looks at how healthcare workers' understanding of ergonomics relates to muscle and bone problems. It may help find ways to prevent work-related pain.
IstanbulAges 25–45 - NCT06758297Recruiting
AI motivational talk after knee replacement
This study tests whether an artificial intelligence-guided motivational conversation can help reduce fear of moving after knee replacement surgery, and improve how much you can move.
Samsun, SamsunAges 18 years+ - NCT06893614Recruiting
Facial mesh study for jaw surgery patients
This trial uses computer scans to create facial shape meshes for patients who had jaw surgery to correct an underbite. It aims to improve planning for future surgeries.
Cairo, AbbassiaAges 18–50 - NCT06601634Recruiting
Neck pain improvement after cervical spine surgery
This study looks at what factors help predict better neck pain after a specific type of neck surgery called ACDF. If you have a degenerative neck condition and are scheduled for this surgery, the results could help doctors understand what leads to the best pain relief.
Krakow, Lesser Poland VoivodeshipAges 18–65 - NCT06874517Recruiting
Foot shape and big toe angle study
This study looks at whether the length of your second toe relates to a condition called hallux valgus (a bunion, where the big toe angles toward the other toes). Researchers will measure foot X-rays to compare two common foot shapes: Greek foot (longer second toe) and Egyptian foot (shorter second toe).
Istanbul, BeylikdüzüAges 60–80 - NCT06890000Recruiting
Scapular exercises for shoulder pain relief
This trial tests if special exercises for the shoulder blade (scapula) can reduce shoulder pain better than standard exercises. It is for people with shoulder pain that has lasted at least one month and who have a shoulder blade that moves incorrectly.
AnkaraAges 18 years+ - NCT07268326Recruiting
Plant-based diet for rheumatoid arthritis
This trial tests whether a plant-based diet can help people with rheumatoid arthritis who have mild disease activity. You must have had RA for at least a year, be on stable medication, and not smoke or take prednisolone.
FrederiksbergAges 18 years+ - NCT07261358Recruiting
3D exercises for teens with rounded upper back
This trial tests whether specific three-dimensional exercises (Schroth method) can improve trunk muscle endurance, sleep quality, and quality of life in adolescents with hyperkyphosis (excessive forward curve of the upper spine). If you have a child between 12 and 18 with a Cobb angle of 45° or more in the upper back, this study may help.
IstanbulAges 12–18 - NCT07261553Recruiting
Exercises at home for muscle and bone conditions
This study looks at how well people follow a home exercise program for muscle or bone problems. It aims to understand what helps or makes it hard to stick with the exercises.
Konya, KonyaAges 18 years+ - NCT07261644RecruitingPhase 3
Study of a new drug for active ankylosing spondylitis
This study tests a new medication (called 608) for adults with active ankylosing spondylitis (AS). It aims to see if the drug can reduce AS symptoms and improve quality of life.
Beijing, Beijing MunicipalityAges 18 years+ - NCT05050409Recruiting
Program to help recovery after knee replacement surgery
This trial tests a supportive, coach-like “embedded” program designed to help you stay engaged and ready for recovery after one knee replacement. It may be helpful if you want extra support before and after surgery to follow through with your recovery plan.
Fort Sam Houston, TexasAges 18 years+ - NCT07262294Recruiting
Deep breathing and core exercises for ankylosing spondylitis
This trial tests whether combining deep breathing with core stability exercises helps people with ankylosing spondylitis. It may improve symptoms and quality of life.
Banī SuwayfAges 25–45 - NCT07266753RecruitingPhase 4
Comparing oral antibiotics for leg and foot bone infections
This trial compares two common types of oral antibiotics to see which works better for bone infections below the knee. If you have a bone infection that needs at least 28 more days of treatment and you can take pills, this study may help find the best option for you.
Ottawa, OntarioAges 18 years+ - NCT07262892Recruiting
3D study of jaw widening methods in children
This trial uses 3D imaging to compare two ways of widening the upper jaw in children. It may help your child if they need jaw expansion and haven't had it before.
Istanbul, FatihAges 6–12 - NCT07267156Recruiting
New Dressing After Bunion Surgery
This study tests a new type of bandage or dressing used after bunion (hallux valgus) surgery. It aims to see if this dressing works better than the usual dressing to help your foot heal.
Geneva, Canton of GenevaAges 18 years+ - NCT07260747Recruiting
Virtual reality for foot health in sedentary students
This trial tests if virtual reality exercises can improve foot function, pressure, and balance in sedentary university students aged 18–25. It may help you understand how simple VR activities can benefit your feet and stability.
IstanbulAges 18–45 - NCT07266038Recruiting
Comparing two wire methods for children's elbow fracture
This trial is testing two ways of using small wires (K-wires) to hold a child's broken elbow bone in place after it's been set. The goal is to see which method keeps the bone correctly aligned as it heals.
Bahawalpur, Punjab ProvinceAges 2–13 - NCT07260318Enrolling by invitation
How fast bowling affects bone health
This study looks at how cricket fast bowling affects your bone health and the signals your body sends to build or break down bone. If you're a healthy young male fast bowler, this trial will help understand the immediate impact of bowling on your bones.
Loughborough, LeicestershireAges 18–30 - NCT07265999Recruiting
Severity factors of dermatomyositis in Caribbean patients
This study looks at what makes dermatomyositis more severe in people of Caribbean background living in Guadeloupe. By understanding these factors, doctors may better manage this rare muscle and skin disease.
Pointe-à-PitreAges 16 years+ - NCT07265154Recruiting
Gait training with AI for above-knee amputees
This trial tests a new way to help people with above-knee amputations improve how they walk, using artificial intelligence to guide their gait training. It may help you walk more naturally and safely.
Banhā, BenhaAges 16–50
Common questions
- How many bones, joints & muscles clinical trials are recruiting?
- Clin2 is tracking 4,610 recruiting rheumatology & orthopedics studies from the U.S. registry right now, out of 7,529 we cover in this area in total.
- What does “Bones, joints & muscles” cover here?
- Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We group each study into bones, joints & muscles based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a bones, joints & muscles trial near me?
- Use the search to filter bones, joints & muscles studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.