Rheumatology & orthopedics
Bones, joints & muscles clinical trials
Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We’re tracking 4,841 recruiting studies in this area right now.
By phase
- Not applicable3,972
- Phase 2224
- Phase 4197
- Phase 1191
- Phase 3149
- Phase 1/Phase 275
- Phase 2/Phase 333
Top conditions
- Knee Osteoarthritis184
- Rheumatoid Arthritis142
- Fibromyalgia102
- Osteoporosis88
- Osteoarthritis74
- Osteoarthritis, Knee72
- Rheumatoid Arthritis (RA)66
- Shoulder Pain50
- Psoriatic Arthritis47
- Hip Osteoarthritis41
- Systemic Lupus Erythematosus41
- Duchenne Muscular Dystrophy39
- Degenerative Disc Disease38
- Chronic Pain37
- Total Knee Arthroplasty37
- Musculoskeletal Pain36
- Pain35
- Dermatomyositis31
Leading sponsors
- Riphah International University110
- Cairo University72
- Istituto Ortopedico Rizzoli71
- Assistance Publique - Hôpitaux de Paris37
- Foundation University Islamabad34
- Mayo Clinic29
- Massachusetts General Hospital27
- National Taiwan University Hospital25
- Chinese University of Hong Kong22
- Hacettepe University22
Where studies are running
- California211
- New York94
- Florida80
- Massachusetts76
- Arizona75
- Maryland73
- Texas65
- Alabama57
- Illinois54
- Pennsylvania50
Recruiting studies4,841 total
- NCT04128670Recruiting
Kinesio tape test for sore muscles after exercise
This study checks whether Kinesio tape changes how sore your muscles feel after workouts. You may help researchers learn if the tape reduces “delayed onset muscle soreness” after upper-body activity.
Indianapolis, IndianaAges 18–30 - NCT04134572Recruiting
Registry for Ollier disease and Maffucci syndrome
This trial is a registry, which means it collects information about people with Ollier disease and Maffucci syndrome. It can help researchers better understand these conditions and plan future studies.
Bologna, Emilia-RomagnaAges Any age - NCT04133285Recruiting
Registry for people with multiple bone growths
This study is a registry that collects information about people with multiple osteochondromas (extra bone/cartilage growths). It may help researchers better understand the condition and improve future care, even if no treatment is given.
Bologna, Emilia-RomagnaAges Any age - NCT04137835Recruiting
Noninvasive motion testing for arm and leg function
This study tests how well your upper and lower body moves using non-invasive methods (no procedures or surgery). It’s likely best for healthy adults who can follow instructions and want to help researchers measure movement and function.
Aurora, ColoradoAges 18–65 - NCT04140344Recruiting
Study texting messages after low back fusion surgery
This study tests whether regular text-message check-ins after lumbar (low back) fusion surgery are helpful for communication and follow-up. It enrolls people who will be getting their first low back fusion and who are comfortable texting and willing to stay in regular contact.
Durham, North CarolinaAges 18 years+ - NCT04152551RecruitingPhase 4
Bisphosphonate use and hearing loss in type 1 osteogenesis imperfecta
This study looks at whether bisphosphonate treatment affects hearing loss in people with type 1 osteogenesis imperfecta. If you qualify, it may help researchers understand if treatment can protect hearing over time.
New York, New YorkAges 6–100 - NCT04153994Recruiting
Numbing injection study for kids’ scoliosis back surgery pain
This trial tests whether a specific numbing injection (placed in the muscles of the back) can improve pain control for children having one-stage scoliosis surgery. It may help reduce post-surgery pain needs and improve comfort.
Palo Alto, CaliforniaAges Up to 18 years - NCT04159675Recruiting
Burosumab and vitamin D for kids needing skull surgery
This study tests whether burosumab and vitamin D affect bone cells before and around the time of craniosynostosis surgery in children. It may help researchers understand treatment options for rare calcium and phosphate bone disorders that can affect skull growth.
BronAges 4 months–18 years - NCT04181970Recruiting
Study of sarcoma care quality across Europe and Latin America
This observational study looks at information from people with sarcoma to understand how care is delivered across different centers. It does not test a new treatment, but may help improve future care and planning.
Buenos AiresAges 18–120 - NCT04182997RecruitingPhase 4
Epidural steroid shot during discectomy for back nerve pain
This trial studies whether giving a steroid medicine into the epidural space during discectomy (back surgery for a herniated disc) helps reduce nerve pain and symptoms. It is mainly for people whose MRI and exam show a single-level lumbar disc herniation after non-surgical treatments didn’t help.
Columbia, MissouriAges 18 years+ - NCT04190953Recruiting
Braces and expanders in kids to improve airflow space
This study looks at how jaw and palate treatments affect airflow through the upper airway in children with a specific bite and jaw shape. It may help researchers understand which treatments improve space for breathing and related pressure changes.
Edmonton, AlbertaAges 8–14 - NCT04191395Recruiting
Study of treatments for long-term inflammatory diseases
This study looks at how chronic inflammatory illnesses progress over time and how treatments affect symptoms and disease markers. You may be invited if you’re receiving care for certain bowel, joint, or skin inflammatory conditions at the hospital.
BesançonAges 18 years+ - NCT04194138Recruiting
Surgery planning study for complex adult spine curvatures
This trial focuses on adults with complex spinal deformities and tests how different surgical approaches fit their x-ray measurements and surgical plans. It may help doctors choose safer, better-tailored surgery for severe adult spine bending or imbalance.
La Jolla, CaliforniaAges 18 years+ - NCT04192344RecruitingPhase 1
First test of an anti-cancer drug for advanced solid tumors
This Phase 1 study tests how safe a new drug (ABSK-021) is, what side effects it causes, and how the body processes it in people with advanced solid tumors. You may be eligible if your cancer has grown despite standard treatments or if no standard treatment exists.
Beverly Hills, CaliforniaAges 18 years+ - NCT04194996Recruiting
Study of surgery for crooked or bent neck alignment
This study looks at how well planned surgery corrects neck (cervical) deformities and how the results change over time. It mainly involves standard pre- and follow-up imaging and study questionnaires to compare clinical and X-ray outcomes.
La Jolla, CaliforniaAges 18 years+ - NCT04194619Recruiting
Study of pregnancy safety in women with rare blood-vessel diseases
This study looks at pregnancy and the early period after birth in women with rare diseases that affect blood vessels. It may help doctors understand risks and improve care for future pregnancies.
AngersAges 18–45 - NCT04195256RecruitingPhase 2/Phase 3
Nasal sedation medicine for kids needing a quick procedure
This trial tests whether a nose spray (dexmedetomidine plus ketamine) can safely and effectively sedate children during an ED procedure for certain arm injuries. It may help reduce distress and improve comfort compared with usual care.
Edmonton, AlbertaAges 2–17 - NCT04209504Recruiting
Nerve block study for one-sided breathing muscle weakness after shoulder surgery
This trial tests whether a longer-lasting nerve block during shoulder surgery can better manage pain and affect one-sided diaphragm (breathing muscle) weakness. It may help people having planned (first-time) shoulder surgery who are able to follow study pain-checks.
Durham, North CarolinaAges 18–80 - NCT04210284Recruiting
Oral nutrition support before hip or knee replacement
This trial tests whether an oral nutrition plan given before elective hip or knee replacement can help people with low nutrition (“malnutrition”) do better after surgery. If you’re a candidate for surgery and meet lab signs of poor nutrition, you may be asked to take an oral supplement by mouth.
New York, New YorkAges 55 years+ - NCT04217603Recruiting
CPAP test to improve walking distance in ECAC
This study looks at whether using CPAP (a breathing device that helps keep airways open) can improve how far you can walk in 6 minutes. It also checks how CPAP may change breathing and exercise test results in people with ECAC.
Boston, MassachusettsAges 18 years+ - NCT04230616Recruiting
Testing a knee device to ease osteoarthritis pain
This study tests how well and how safely a knee treatment works for adults with painful knee osteoarthritis seen on X-ray. You might join if you need meaningful pain relief and help with daily function, and can complete required scans and study instructions.
Sint-Truiden, LimburgAges 18 years+ - NCT04238143Recruiting
Knee and other joint arthritis tissue therapy
This trial tests a regenerative therapy made from a patient’s own fat tissue (a “cellular” treatment) to reduce pain and improve function in arthritis-related problems. It may help people with inflammatory or degenerative arthritis changes, if they meet safety and tissue-donation requirements.
Valencia, CaliforniaAges 18–90 - NCT04244942Recruiting
CERAMENT bone filler registry for people having bone surgery
This registry study collects information about people who receive CERAMENT™ as part of their bone surgery. It helps doctors understand how the device is used in real-world care and may improve future treatment planning.
Scottsdale, ArizonaAges 18 years+ - NCT04246944Recruiting
Induced membrane bone repair study in critical defects
This study looks at how a specific bone-repair technique (called induced membrane reconstruction) works in people with large “critical-sized” bone defects. It may help doctors understand the results and properties of this method in both children and adults.
AmiensAges 9 months–60 years
Common questions
- How many bones, joints & muscles clinical trials are recruiting?
- Clin2 is tracking 4,841 recruiting rheumatology & orthopedics studies from the U.S. registry right now, out of 7,961 we cover in this area in total.
- What does “Bones, joints & muscles” cover here?
- Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We group each study into bones, joints & muscles based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a bones, joints & muscles trial near me?
- Use the search to filter bones, joints & muscles studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.