Rheumatology & orthopedics
Bones, joints & muscles clinical trials
Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We’re tracking 4,611 recruiting studies in this area right now.
By phase
- Not applicable3,768
- Phase 2217
- Phase 4200
- Phase 1182
- Phase 3139
- Phase 1/Phase 271
- Phase 2/Phase 334
Top conditions
- Knee Osteoarthritis172
- Rheumatoid Arthritis132
- Fibromyalgia105
- Osteoporosis82
- Osteoarthritis71
- Rheumatoid Arthritis (RA)68
- Osteoarthritis, Knee64
- Shoulder Pain48
- Hip Osteoarthritis43
- Psoriatic Arthritis40
- Degenerative Disc Disease39
- Chronic Pain38
- Total Knee Arthroplasty38
- Duchenne Muscular Dystrophy37
- Systemic Lupus Erythematosus37
- Musculoskeletal Pain35
- Osteoarthritis (OA) of the Knee32
- Pain32
Leading sponsors
- Riphah International University85
- Istituto Ortopedico Rizzoli69
- Cairo University65
- Assistance Publique - Hôpitaux de Paris36
- Foundation University Islamabad31
- Mayo Clinic28
- Massachusetts General Hospital25
- National Taiwan University Hospital25
- Hacettepe University23
- Tanta University22
Where studies are running
- California207
- New York87
- Florida82
- Maryland76
- Arizona72
- Massachusetts71
- Texas67
- Alabama59
- Illinois51
- Pennsylvania48
Recruiting studies4,611 total
- NCT07857798Recruiting
How your body traits relate to growth and development
This study looks at how different physical traits, like height and body shape, relate to growth and development. By participating, you'll help researchers understand normal human variation, which may improve future health care.
Guangzhou, GuangdongAges 18–60 - NCT07855419Recruiting
Muscle loss and steroid injections for lumbar spinal stenosis
This study looks at whether the amount of muscle loss (sarcopenia) affects how well steroid injections into the spine work for people with lumbar spinal stenosis, a condition that causes back and leg pain from narrowing of the spinal canal.
Istanbul, IstanbulAges 50–75 - NCT07867405Recruiting
Sheep tail fat for knee arthritis pain
This study tests whether applying sheep tail fat to the knee can reduce pain, stiffness, and make daily activities easier for people with knee arthritis (gonarthrosis). It may be an option if you have had knee pain for at least three months and want a natural, non-drug treatment to try at home.
BitlisAges 18 years+ - NCT07865403Recruiting
Online psychological support for fibromyalgia
This trial tests an online program that combines psychological support with physical rehabilitation to help manage fibromyalgia symptoms. It aims to improve well-being and daily functioning from home.
Rome, RomeAges 18–70 - NCT07863232Recruiting
Melatonin and nutrition for fibromyalgia pain relief
This study tests whether taking melatonin, a sleep and pain hormone, along with special nutrition supplements, can help reduce fibromyalgia pain. It may offer a new way to manage symptoms.
LarissaAges 18 years+ - NCT06181097Recruiting
Negative pressure wound therapy after knee or hip replacement
This study tests whether using a special bandage that applies gentle suction (negative pressure wound therapy) after knee or hip replacement helps incisions heal better. It may reduce wound complications and improve recovery.
Hong KongAges 50 years+ - NCT05847270Recruiting
Surgery for a neck bone dislocation that can’t be put back
This study looks at surgical treatment for a specific type of neck bone dislocation that cannot be corrected without surgery. It may help patients whose imaging and traction testing show they need an operation to stabilize the neck.
Beijing, Beijing MunicipalityAges Up to 80 years - NCT07855887Recruiting
Calcium injection for jaw joint disc pain
This trial tests a calcium gluconate injection into the jaw joint for people with painful jaw joint disc displacement that hasn't improved with other treatments. The injection may help reduce pain and improve jaw function.
CairoAges 18–65 - NCT07856147Recruiting
Massage and scraping therapy for heel pain
This study compares two non-surgical treatments for plantar fasciitis, a common cause of heel pain. One uses deep friction massage and the other uses a special scraping tool. Both aim to reduce pain and improve function.
Islamabad, Punjab ProvinceAges 19–44 - NCT06142669Recruiting
Knee revision study using EVOLUTION parts
This study checks how well a specific knee replacement system works in people who need a revision knee surgery (replacing a previous implant). If you have had or will have this surgery with the EVOLUTION parts, researchers will follow you for 10 years to see how the implant performs.
Milan, Piazza C. Ferrari 1 20122 MilanAges 21 years+ - NCT05935709Recruiting
Danish database study for GCA or PMR
This study builds and uses a Danish database for people diagnosed with giant cell arteritis (GCA) or polymyalgia rheumatica (PMR). It may help doctors learn more about these conditions over time and improve care.
AarhusAges 50 years+ - NCT05809323Recruiting
Trial testing moderate exercise in teens with Marfan syndrome
This trial studies whether doing moderate exercise is safe and helpful for people with Marfan syndrome. It aims to see how exercise affects heart and health measures, like how the aorta and body respond over time.
Houston, TexasAges 10–25 - NCT06221709Recruiting
Radiofrequency for hip arthritis pain: a clinical trial
This trial tests whether a treatment called continuous radiofrequency can reduce pain from hip arthritis. It is for people with moderate arthritis in one hip who have had pain for more than six months.
Brasília, Federal DistrictAges 18 years+ - NCT04623593Recruiting
Study of cost and value of neck disc surgery
This study looks at how cost-effective (good value for the money) anterior neck disc surgery is for people with nerve or spinal cord symptoms. If you need this type of operation, it may help doctors better choose treatments and plan healthcare resources.
Maastricht, LimburgAges 18 years+ - NCT04688593Recruiting
Follow-up study of a hip implant cup and stem system
This study looks at how well a specific hip implant (the acetabular cup and femoral stem) works over short, mid, and long-term follow-up. It may help you and other patients by improving understanding of implant outcomes after surgery.
KielAges 18 years+ - NCT07855393Recruiting
Back shape and spine damage in ankylosing spondylitis
This study looks at how the shape of your back relates to spine damage in people with ankylosing spondylitis. It uses a special 3D scanner to measure your back and compares it with your X-rays to see if the scanner can help track the disease.
Ankara, YenimahalleAges 18–65 - NCT07858734RecruitingPhase 2
Pain relief after bunion surgery
This study tests a new pain medicine given during bunion surgery to see how well it controls pain after the operation. It may reduce the need for other painkillers.
Sherbrooke, QuebecAges 18–75 - NCT05904353Recruiting
Care coordination program after hip fracture and osteoporosis
This trial aims to improve how primary care and hospital care work together to treat osteoporosis after a hip fracture. It may help by making follow-up treatment plans and communication clearer after your hip injury.
Lørenskog, AkershusAges 75 years+ - NCT07854288Recruiting
Shoulder exercises with or without massage for frozen shoulder
This study compares two types of physical therapy for frozen shoulder (a condition where the shoulder becomes stiff and painful). It looks at whether adding a specific massage technique to a standard joint exercise gives better results than the exercise alone.
LahoreAges 40–60 - NCT06143254Recruiting
Infant sign training for speech development
This trial tests whether teaching infants with cleft palate simple signs can help them communicate before they can speak. It may support their speech and language development.
Ghent, East FlandersAges 1–2 - NCT06237153RecruitingPhase 2
Steroid injection for thumb arthritis pain
This study tests a long-acting steroid injection for thumb arthritis at the base of the thumb. It aims to reduce pain and improve function in people with mild to moderate joint damage.
Stony Brook, New YorkAges 18 years+ - NCT05495399Recruiting
Radiation after limited spine surgery for spine metastases
This study tests whether radiation given after limited surgery helps control cancer that has spread to a small area of the spine. It may help reduce tumor growth in the treated spine area and improve local control after operation.
TaipeiAges 20 years+ - NCT05898243Recruiting
Study of injuries after shoulder dislocation in adults over 40
This study follows people over age 40 who have their first traumatic “front” shoulder dislocation to learn what injuries happen and how they can be identified. It may help doctors better understand what to check for after this kind of injury.
Sabadell, BarcelonaAges 40 years+ - NCT06249958Recruiting
Personalized rehabilitation after hip or knee replacement
This study looks at how personalized rehabilitation after hip or knee replacement surgery can improve your quality of life. It is for people who had their surgery at IRCCS Galeazzi Orthopedic Institute in 2019.
Milan, ItaliaAges 18 years+
Common questions
- How many bones, joints & muscles clinical trials are recruiting?
- Clin2 is tracking 4,611 recruiting rheumatology & orthopedics studies from the U.S. registry right now, out of 7,492 we cover in this area in total.
- What does “Bones, joints & muscles” cover here?
- Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We group each study into bones, joints & muscles based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a bones, joints & muscles trial near me?
- Use the search to filter bones, joints & muscles studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.