Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,425 recruiting studies in this area right now.
By phase
- Not applicable9,762
- Phase 2784
- Phase 1574
- Phase 3535
- Phase 4342
- Phase 1/Phase 2305
- Phase 2/Phase 3123
Top conditions
- Stroke845
- Parkinson Disease426
- Multiple Sclerosis343
- Alzheimer Disease341
- Dementia226
- Ischemic Stroke200
- Epilepsy197
- Obstructive Sleep Apnea155
- Spinal Cord Injuries154
- Insomnia153
- Sarcopenia149
- Traumatic Brain Injury149
- Acute Ischemic Stroke139
- Cerebral Palsy131
- Mild Cognitive Impairment129
- Pain Management114
- Migraine112
- Amyotrophic Lateral Sclerosis108
Leading sponsors
- Beijing Tiantan Hospital133
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing94
- VA Office of Research and Development93
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California678
- Massachusetts300
- New York292
- Florida275
- Texas267
- Maryland245
- Arizona213
- Alabama211
- Illinois189
- Pennsylvania178
Recruiting studies12,423 total
- NCT05733520Recruiting
Telehealth coaching for Alzheimer’s caregivers using a phone
This trial tests a mobile telehealth program designed to help unpaid caregivers reduce Alzheimer’s-related symptoms in the people they care for. If you’re a primary caregiver, you may get study sessions using a smartphone or similar device.
Indianapolis, IndianaAges 18 years+ - NCT05734378Recruiting
Study aims to predict outcomes in small blood vessel brain disease
This trial is looking at how brain “small blood vessel disease” changes over time and what outcomes to expect. If you have certain symptoms or scan findings from this condition, your care team may compare your prognosis to help guide future treatment planning.
BernAges 16 years+ - NCT05734404Recruiting
Long-term study of brain vessel inflammation
This study follows adults diagnosed with inflammation of blood vessels in the brain (CNS vasculitis). It aims to better understand the condition over time and could help improve how it’s diagnosed and managed.
Rochester, MinnesotaAges 18 years+ - NCT05734547Recruiting
Support for children after trauma through parent-and-child sessions
This trial offers a structured program for children who have ongoing trauma symptoms after a scary or harmful event, with work involving both the child and a parent/caregiver. It aims to reduce post-trauma stress symptoms and help the child feel safe again.
AskerAges 7–12 - NCT05734521Recruiting
Study of avalglucosidase alfa use during pregnancy
This study collects safety information about avalglucosidase alfa when it’s taken during pregnancy and/or while breastfeeding. If you (or your baby) were exposed to this medicine and consent to be in a pregnancy safety registry, your information may help researchers better understand risks.
Bridgewater, New JerseyAges Any age - NCT05735444Recruiting
CPAP registry for sleep apnea in people with high blood pressure
This study keeps a record of people with obstructive sleep apnea (OSA) who also have high blood pressure, to better understand how CPAP is used and what outcomes happen. It may help your care team by contributing your information to a large multi-center study in China.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT05735691Recruiting
Gait training for people with multiple sclerosis using treadmill exercises
This study tests a high-intensity treadmill walking program designed to improve walking stability for people with multiple sclerosis (MS). It may help you build safer, more confident walking, but you must meet several health and ability requirements to take part.
Indianapolis, IndianaAges 18–75 - NCT05736302Recruiting
Check an activity-tracking algorithm against a body-weight test
This trial checks whether a new computer algorithm that uses an accelerometer (movement sensor) can accurately estimate your body’s activity and energy use. It compares the phone/wearable movement data to results from a special way of measuring how your body uses energy.
Milwaukee, WisconsinAges 18 years+ - NCT05738083Recruiting
Study builds prediction tools after aneurysm bleeding
This study looks at early test results and brain scans to predict outcomes after an aneurysm causes subarachnoid hemorrhage. It mainly collects information to build a risk prediction model, which may help doctors plan care more effectively in the future.
Nanchang, JiangxiAges 18 years+ - NCT05738096RecruitingEarly Phase 1
Testing nerve recordings to improve facial pain rhizotomy
This study looks at special nerve testing (nerve recordings) in adults who are scheduled for a procedure called percutaneous rhizotomy for facial pain. The goal is to see whether these recordings can help improve how the procedure works and affects pain.
Minneapolis, MinnesotaAges 18 years+ - NCT05738278Recruiting
Care changes guided by heart rate in non-speaking autistic people
This study tests whether using a person’s heart rate to guide care can improve day-to-day support for autistic people who do not communicate verbally. It’s aimed at people who live in a care home or attend a staffed day program most days of the week.
OsloAges 5–70 - NCT05738824Recruiting
Study how inflammatory muscle diseases naturally change over time
This study follows people with suspected or confirmed inflammatory muscle disease (and sometimes healthy adults) to better understand how the condition progresses and what changes over time. It may help researchers identify patterns that could guide future treatments.
Bethesda, MarylandAges 2–120 - NCT05740605Recruiting
Testing an at-home therapy program for bilateral cerebral palsy
This trial tests an at-home intervention (called HABIT-ILE) for children with bilateral cerebral palsy, delivered over two weeks. It aims to see whether home-based therapy and assessments help children function better and whether families can follow the program.
BrusselsAges 5–18 - NCT05740761Recruiting
Gene editing for children with Rett syndrome
This trial tests a gene-editing approach for Rett syndrome in children who have a confirmed MECP2 gene mutation. It may help by targeting specific “hotspot” genetic changes that cause the condition.
Siena, SienaAges 6 months+ - NCT05740722RecruitingPhase 2
Nicotinamide riboside for progressive multiple sclerosis
This Phase 2 trial studies whether a vitamin-like supplement called nicotinamide riboside can slow or improve disability in progressive multiple sclerosis. It may help people whose symptoms have been steadily getting worse over the last 2 years.
BergenAges 18–65 - NCT05740735Recruiting
Testing sound-based brain signals to predict recovery after severe brain injury
This study checks how a brain responds to two kinds of sounds—neutral tones and emotional sounds—in people with a persistent disorder of consciousness after a serious event like stroke, head injury, or cardiac arrest. The goal is to see whether these brain “signal” tests can help doctors predict outcomes.
Paris, IDFAges 18 years+ - NCT05741112Recruiting
Long COVID wearable study to track symptoms and help daily management
This study uses a wearable device to track symptoms and patterns in people with Long COVID, ME/CFS, and/or POTS. The goal is to see how wearable feedback and tracking tools may help you manage your symptoms.
La Jolla, CaliforniaAges 18 years+ - NCT05741411Recruiting
Text-and-phone support after concussion for teens
This study tests whether a phone-based (mHealth) handoff and follow-up can help teens after a concussion, especially those at higher risk of long-lasting symptoms. It uses smartphone check-ins and coordination between emergency and specialty care.
Philadelphia, PennsylvaniaAges 13–18 - NCT05741151Recruiting
Testing a nerve target in Parkinson’s disease
This trial is studying the “superior cervical ganglion” as a possible treatment approach for Parkinson’s disease. It may help people whose symptoms are truly caused by Parkinson’s, not by another condition.
RomeAges 30–80 - NCT05741593Recruiting
Interview study for older adults after ischemic stroke
This study talks with people age 65+ who were hospitalized for an ischemic stroke and are already on blood-thinning medicines to learn about their experiences. The interviews may help improve how pharmacists support patients after stroke.
VilleurbanneAges 65–100 - NCT05741775RecruitingPhase 3
Physiotherapy program for migraine symptoms
This trial tests whether a physiotherapy treatment can reduce migraine symptoms. You may be eligible if you have likely migraine headaches and meet the trial’s symptom screening rules.
Kajang, SelangorAges 18–40 - NCT05741905Recruiting
Levofloxacin antibiotic with IV clot-busting for acute stroke
This trial tests whether adding the antibiotic levofloxacin to standard IV clot-busting treatment is safe and improves outcomes after an acute ischemic stroke. It may help by reducing complications related to infection or inflammation, but you must meet specific heart, liver, kidney, and medication-safety rules.
Changchun, JilinAges 18–75 - NCT05741853Recruiting
Speech therapy study for bilingual people with primary progressive aphasia
This study looks at how well speech-language therapy works in bilingual people with primary progressive aphasia, a condition that gradually affects language. It also tests whether different language skills (Spanish/Catalan or Spanish/English) affect response to treatment.
Austin, TexasAges 40 years+ - NCT05742776Recruiting
Ultrasound and sleep quality check in carpal tunnel
This trial studies whether ultrasound exam findings match how well you sleep if you have carpal tunnel syndrome. It may help doctors better understand which ultrasound results go along with worse sleep and symptoms.
Afyonkarahisar, Afyonkarahi̇sarAges 20–80
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,425 recruiting neurology studies from the U.S. registry right now, out of 19,436 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.