Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 11,975 recruiting studies in this area right now.
By phase
- Not applicable9,368
- Phase 2765
- Phase 1561
- Phase 3516
- Phase 4338
- Phase 1/Phase 2301
- Phase 2/Phase 3126
Top conditions
- Stroke799
- Parkinson Disease395
- Alzheimer Disease339
- Multiple Sclerosis330
- Dementia227
- Epilepsy194
- Ischemic Stroke190
- Insomnia159
- Traumatic Brain Injury151
- Obstructive Sleep Apnea142
- Spinal Cord Injuries142
- Acute Ischemic Stroke140
- Sarcopenia134
- Mild Cognitive Impairment129
- Cerebral Palsy120
- Pain Management116
- Migraine107
- Fibromyalgia104
Leading sponsors
- Beijing Tiantan Hospital125
- Assistance Publique - Hôpitaux de Paris110
- Riphah International University105
- Mayo Clinic98
- VA Office of Research and Development91
- Xuanwu Hospital, Beijing89
- Hospices Civils de Lyon77
- Johns Hopkins University70
- University of Minnesota63
- Washington University School of Medicine63
Where studies are running
- California662
- Massachusetts306
- New York296
- Florida272
- Texas267
- Maryland249
- Alabama206
- Arizona206
- Illinois181
- Pennsylvania177
Recruiting studies11,975 total
- NCT07299448Recruiting
Parkinson's and swallowing: what drives difficulty?
This study looks at why some people with Parkinson's have trouble swallowing (dysphagia) and how the brain adapts. It aims to understand the condition better, which could lead to better treatments.
Düsseldorf, North Rhine-WestphaliaAges 18 years+ - NCT07302750Recruiting
AI breathing and relaxation training for postmenopausal women
This trial tests if an AI-guided breathing and relaxation program can help reduce chronic pain in postmenopausal women. You would use a smartphone or tablet to follow online sessions and track your progress.
AnkaraAges 45–65 - NCT07298655Recruiting
3D ultrasound to see new blood vessels in carotid plaque
This trial uses a special 3D ultrasound with contrast dye to look at fatty buildup (plaque) in the neck arteries. It aims to find new, fragile blood vessels in the plaque that might increase stroke risk.
HarrowAges 18 years+ - NCT07299006Recruiting
Study of a robot to help manage pain during IV placement in children
This trial tests whether a friendly robot named Paro can help reduce pain and anxiety in young children when they need an IV placed. If your child is between 1 and 7 years old and needs an IV, this study may help make the procedure less stressful.
BrestAges 1–7 - NCT07303998Recruiting
Brain stimulation and chair yoga for knee pain in Alzheimer's
This study tests two treatments together for people with Alzheimer's who also have chronic knee pain: a gentle brain stimulation (tDCS) and online chair yoga. The goal is to see if these can reduce knee pain and improve daily life.
Tucson, ArizonaAges 60 years+ - NCT06876857Recruiting
UCF Cerebrospinal Fluid Biobank for Adults
This is a research biobank at the University of Central Florida that collects and stores cerebrospinal fluid samples for future studies. It is open to most adults who can give their consent.
Orlando, FloridaAges 18 years+ - NCT04524637Recruiting
Testing a clotting test in recent traumatic brain injury
This trial tests whether a special blood clotting test called thromboelastography can help assess clotting problems after a head injury. It may help doctors better understand bleeding risk and related complications early after trauma.
ShanghaiAges 18–80 - NCT06876285Recruiting
Wheelchair treadmill vs. standard exercises for trunk balance after spinal cord injury
This study compares wheelchair treadmill training with regular exercises to see which better improves trunk (core) balance for people with spinal cord injuries. If you use a manual wheelchair and have an injury at T6 or below, this trial may help you find a better way to strengthen your core.
AnkaraAges 18 years+ - NCT06876688RecruitingPhase 2
Relma-cel and Tislelizumab for CNS Lymphoma
This trial tests a combination of two drugs for people with large B-cell lymphoma that has spread to the brain or spinal cord and has come back or not responded well to earlier treatments. The first drug, Relma-cel, is a type of immunotherapy that helps your immune system attack cancer cells. The second drug, Tislelizumab, helps keep your immune system active against the cancer.
BeijingAges 18 years+ - NCT04956549Recruiting
Exercise program for early memory loss in African Americans
This study tests whether a structured exercise program can lower Alzheimer’s risk in older African American adults who have mild cognitive impairment (MCI). You’ll be placed by chance into an exercise group or a comparison group and attend group sessions for about a year.
Baton Rouge, LouisianaAges 60 years+ - NCT05499741Recruiting
Heat-based therapy to improve sleep in adults with Tourette’s
This trial tests a forehead temperature-regulating therapy to help improve insomnia symptoms in adults who have Tourette’s (and significant tics). It may help you sleep better by testing whether changing forehead temperature can improve sleep quality and efficiency.
Los Angeles, CaliforniaAges 18–50 - NCT06874231Recruiting
Brain connectivity marker for Alzheimer's disease
This study uses brain scans to find a marker for Alzheimer's disease. It is looking for people with normal memory, mild memory problems, or mild Alzheimer's, and who can undergo a spinal tap and MRI.
Stockholm, SolnaAges 40–85 - NCT06289114Recruiting
Can physical activity predict treatment success in rheumatoid arthritis?
This study tests if measuring your physical activity over a short time can help predict how well a new biologic medication will work for your rheumatoid arthritis. The goal is to find a simple way to see if the treatment is helping.
EsbjergAges 18 years+ - NCT06296810Recruiting
Smart brain stimulation for Parkinson's during exercise
This study tests if a smart brain stimulator (deep brain stimulation, or DBS) can adjust itself during exercise to help people with Parkinson's disease move better. The goal is to improve how well the device works while you're active.
Aurora, ColoradoAges 20–70 - NCT06488313RecruitingPhase 2
Study of ARCT-810 for people with OTC deficiency
This trial tests an experimental medicine called ARCT-810 for people with Ornithine Transcarbamylase (OTC) deficiency, a condition that affects the liver's ability to remove ammonia from the body. The study aims to see if ARCT-810 can help lower ammonia levels safely.
Chevy Chase, MarylandAges 12 years+ - NCT06540651Recruiting
Light therapy for chronic cluster headache
This study tests whether daily light therapy can reduce the number of cluster headache attacks in people with chronic cluster headache. It is a non-drug treatment that uses a special lamp to see if it helps calm your headache cycles.
MarseilleAges 18 years+ - NCT06857110Recruiting
Nerve block vs. hematoma block for wrist fracture pain
This study compares two ways to manage pain when a broken wrist is realigned without surgery: a nerve block near the elbow vs. a numbing injection directly into the fracture. It may help researchers find which method works better and is more comfortable for you.
Bogotá, Bogota D.C.Ages 18 years+ - NCT06849609RecruitingEarly Phase 1
Gene therapy VGN-R13 for ALS safety and tolerability
This study tests a new gene therapy called VGN-R13 for people with ALS. It aims to see if the treatment is safe and tolerable, and if it can slow down the disease. You may be able to join if your ALS symptoms started recently and your lung function is still fairly good.
Wuhan, HubeiAges 18 years+ - NCT07293780Recruiting
TMS for nerve pain after spinal cord injury
This trial tests whether transcranial magnetic stimulation (TMS), a non-invasive brain stimulation, can help relieve nerve pain in people with spinal cord injury. It is for those who have had chronic nerve pain for at least 6 months that hasn't improved with standard treatments.
Ankara, YenimahalleAges 18–65 - NCT07291141Recruiting
MRI vs. Ultrasound for Liver Cancer Detection in Cirrhosis
This study compares MRI and ultrasound to see which is better at finding liver cancer early in people with liver cirrhosis. It also looks at body composition and other factors that could lead to worsening liver function.
Linköping, Select A State Or ProvinceAges 18 years+ - NCT06879743Recruiting
Gentle neck release for fibromyalgia pain
This study tests whether a gentle hands-on technique called suboccipital release can help ease fibromyalgia pain. It’s for women aged 20–45 with a stable fibromyalgia diagnosis who do not have certain other conditions or use strong pain medications.
CairoAges 20–45 - NCT07293546Enrolling by invitationPhase 1/Phase 2
Gene therapy trial for FOXG1 syndrome
This trial tests a gene therapy called FRF-001 for people with FOXG1 syndrome. It aims to see if the treatment is safe and can help improve symptoms.
Oakland, CaliforniaAges 2–20 - NCT07290751RecruitingPhase 4
Adding tirofiban to clot-busting for stroke patients
This trial tests whether adding a second medicine (tirofiban) to standard clot-busting treatment can help people who are not improving after the first hour. It is for people with a moderate to severe stroke who are not candidates for a clot-removal procedure.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07295652Recruiting
Understanding thinking problems in brain disorders
This study looks at how psychiatric and neurological conditions affect thinking and memory skills. By comparing patients with healthy volunteers, researchers hope to better understand these cognitive problems and find new ways to help.
ParisAges 18 years+
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 11,975 recruiting neurology studies from the U.S. registry right now, out of 18,541 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.