Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,407 recruiting studies in this area right now.
By phase
- Not applicable9,740
- Phase 2781
- Phase 1578
- Phase 3536
- Phase 4343
- Phase 1/Phase 2306
- Phase 2/Phase 3123
Top conditions
- Stroke841
- Parkinson Disease429
- Multiple Sclerosis345
- Alzheimer Disease341
- Dementia226
- Ischemic Stroke201
- Epilepsy197
- Obstructive Sleep Apnea156
- Spinal Cord Injuries154
- Insomnia152
- Traumatic Brain Injury150
- Sarcopenia149
- Acute Ischemic Stroke137
- Cerebral Palsy131
- Mild Cognitive Impairment129
- Migraine114
- Pain Management113
- Amyotrophic Lateral Sclerosis108
Leading sponsors
- Beijing Tiantan Hospital133
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic98
- Xuanwu Hospital, Beijing93
- VA Office of Research and Development92
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California681
- Massachusetts299
- New York292
- Florida273
- Texas268
- Maryland246
- Arizona214
- Alabama210
- Illinois189
- Pennsylvania175
Recruiting studies12,405 total
- NCT06100393Recruiting
New sound processing for better hearing in cochlear implant users
This trial tests new sound-processing software in cochlear implants to help users hear speech better in noisy places. It may help adult implant users who struggle with conversations in background noise.
Melbourne, VictoriaAges 18 years+ - NCT07256704Recruiting
Hypnosis and attention for neurological conditions
This study looks at whether hypnosis can help improve attention in people with conditions like stroke, traumatic brain injury, or multiple sclerosis. It may help if you have trouble concentrating or focusing.
LucerneAges 18 years+ - NCT06518057RecruitingPhase 2
Sparing memory during brain radiation for leptomeningeal metastases
This trial tests a special type of radiation that avoids the memory center of the brain (the hippocampus) while treating cancer that has spread to the lining of the brain and spinal cord. It may help reduce side effects on thinking and memory for people with breast or lung cancer.
San Francisco, CaliforniaAges 18 years+ - NCT06458959Enrolling by invitation
Web-based care planning guide for parents in early intervention
This study is testing a new web-based guide to help parents and caregivers make care plans for their child in early intervention. If you join, you'll use the guide and share your feedback to see if it's useful.
Chicago, IllinoisAges 18 years+ - NCT05076617Enrolling by invitationPhase 3
Testing a long-acting rescue seizure medicine for prolonged seizures
This Phase 3 study tests the safety and side effects of Staccato alprazolam for teens and adults (12+) who have certain types of long-lasting seizures. It may help people by offering a specific medicine option aimed at stopping prolonged seizure episodes under close medical study.
Phoenix, ArizonaAges 12 years+ - NCT06870812Recruiting
Quick removal of brain bleed clot study
This trial tests a rapid procedure to remove a blood clot in the brain after a specific type of stroke. It might help people with a moderate-sized bleed in the front part of the brain if treatment can start within 24 hours.
Birmingham, AlabamaAges 18–70 - NCT05958381Recruiting
Brain stimulation for memory problems in relapsing MS
This trial studies a noninvasive brain stimulation treatment to improve memory (specifically memory recall) in people with relapsing-remitting multiple sclerosis (RRMS). It may help if your memory testing shows a “retrieval” problem, and if you’re able to follow the study treatment and safety requirements.
Richardson, TexasAges 18–65 - NCT05412394RecruitingPhase 4
Once-weekly steroid for very young children with DMD
This trial tests whether a steroid taken once each week is safe and useful for children with Duchenne muscular dystrophy (DMD). It aims to help slow disease effects in very young children whose diagnosis and lab tests confirm DMD.
Chicago, IllinoisAges 1 month–2.5 years - NCT07623668RecruitingPhase 3
Testing a new drug for sudden vision loss from nerve inflammation
This study tests whether a new medication called privosegtor can help restore vision in people who recently experienced sudden vision loss in one eye due to optic nerve inflammation. You would receive the study drug early after your symptoms start, when treatment may be most effective.
Livonia, MichiganAges 18–50 - NCT06400186Recruiting
Walking training to improve balance after stroke
This trial tests a new walking training method designed to help you improve your balance after a stroke. It's for people who have had a stroke more than 6 months ago and can walk a short distance, with or without a cane or simple ankle brace.
Chicago, IllinoisAges 18–80 - NCT06447597RecruitingPhase 2/Phase 3
Study of B007 for Generalized Myasthenia Gravis
This trial tests a new drug called B007 for people with generalized myasthenia gravis who have specific antibodies and moderate to severe muscle weakness. It aims to see if the drug can improve daily activities and reduce symptoms.
BeijingAges 18–70 - NCT06293300RecruitingPhase 2
Botulinum toxin for light sensitivity after brain injury
This study tests if botulinum toxin type A (Botox) can reduce long-term light sensitivity in people who have had a traumatic brain injury at least a year ago. You must have had light sensitivity for 6 months or more and not have had Botox for face or mouth conditions before.
Miami, FloridaAges 18 years+ - NCT07098572Recruiting
Comparing two types of electrical stimulation for arm recovery after stroke
This study tests whether a four-channel electrical stimulation device works better than a standard one-channel device for improving arm and hand movement in people who recently had a stroke. The goal is to help with recovery of daily activities.
Hermagor, CarinthiaAges 18–99 - NCT07304154RecruitingPhase 1
Study of KITE-363 for autoimmune nerve diseases
This trial tests a new treatment called KITE-363 for people with certain autoimmune nerve diseases, such as multiple sclerosis, myasthenia gravis, or chronic inflammatory demyelinating polyneuropathy, that have not responded well to standard therapies. The goal is to see if it is safe and effective.
Newport Beach, CaliforniaAges 18–75 - NCT06194162Recruiting
Weighted blankets for better sleep in kids with ADHD
This trial tests if weighted blankets can help children with ADHD who still have trouble sleeping after trying standard sleep tips. The study looks at whether these special blankets improve sleep and daily life.
FrederiksbergAges 5–12 - NCT06540144Enrolling by invitationPhase 3
Extended rozanolixizumab treatment for children with myasthenia gravis
This study continues treatment for children who took part in an earlier trial (MG0006) for generalized myasthenia gravis. It tests 6-week cycles of a drug called rozanolixizumab to see if it continues to work well and stay safe.
BolognaAges 2 years+ - NCT06386029Recruiting
Bedtime routine study for children with autism
This study tests a new bedtime routine designed to help children with autism who are very sensitive to sensory input and have trouble settling down at night. It may help your child fall asleep more easily.
Pittsburgh, PennsylvaniaAges 6–10 - NCT07742189Recruiting
Medication teamwork study for older adults with memory problems
This study looks at how older adults with memory problems and their family caregivers can work together to manage medications. It aims to see if a new way of collaborating is helpful and feasible.
Chicago, IllinoisAges 60 years+ - NCT07543861RecruitingPhase 1
Standing Balance Training Study for Parkinson's Disease
This study tests a new way to help people with Parkinson's disease improve their balance and standing ability through guided exercises in a lab setting. Researchers want to see if this approach can safely help reduce balance problems and fall risk.
Ann Arbor, MichiganAges 50 years+ - NCT07226453RecruitingPhase 2
Metformin for recurrent PFA ependymoma
This trial tests if metformin can help treat a certain type of brain tumor called PFA ependymoma that has come back after surgery and radiation. It's for people ages 1 to 39 who are healthy enough for surgery or have tumors that can be measured on scans.
Birmingham, AlabamaAges 1–39 - NCT07325292RecruitingPhase 3
Frexalimab injection vs IV for multiple sclerosis
This study tests if a new injection (frexalimab) works as well as the IV version for people with relapsing or certain types of secondary progressive multiple sclerosis. It could offer a more convenient way to receive this treatment at home.
Cullman, AlabamaAges 18–60 - NCT03713125Enrolling by invitation
Study of thinking skills in young children
This study looks at how children in kindergarten think and learn (often called “executive function”). They may be testing whether certain patterns in thinking and behavior relate to learning or development, and what can be measured in young children.
Nashville, TennesseeAges 4–9 - NCT06822543RecruitingPhase 2
A new treatment for lung cancer that has spread to the brain
This trial tests a combination of three drugs (datopotamab deruxtecan, carboplatin, and pembrolizumab) for people with a type of lung cancer called non-small cell lung cancer (NSCLC) that has spread to the brain and has not been treated before. The goal is to see if this combination can shrink tumors in the brain and elsewhere.
Fortaleza, CearáAges 18 years+ - NCT07523113Recruiting
Brain Fog Treatment for ME/CFS Using Cognitive Training
This study tests whether a computerized cognitive training program combined with a mild electrical nerve stimulation device (worn on the ear) can help improve thinking and memory problems in people with ME/CFS. The goal is to see if this approach helps with brain fog and daily functioning.
Birmingham, AlabamaAges 18 years+
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,407 recruiting neurology studies from the U.S. registry right now, out of 19,231 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.