Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 11,934 recruiting studies in this area right now.
By phase
- Not applicable9,337
- Phase 2764
- Phase 1555
- Phase 3514
- Phase 4340
- Phase 1/Phase 2299
- Phase 2/Phase 3125
Top conditions
- Stroke797
- Parkinson Disease395
- Alzheimer Disease337
- Multiple Sclerosis330
- Dementia224
- Epilepsy192
- Ischemic Stroke190
- Insomnia159
- Traumatic Brain Injury151
- Obstructive Sleep Apnea142
- Spinal Cord Injuries142
- Acute Ischemic Stroke139
- Sarcopenia135
- Mild Cognitive Impairment126
- Cerebral Palsy119
- Pain Management113
- Migraine107
- Fibromyalgia105
Leading sponsors
- Beijing Tiantan Hospital124
- Assistance Publique - Hôpitaux de Paris109
- Riphah International University105
- Mayo Clinic98
- VA Office of Research and Development92
- Xuanwu Hospital, Beijing89
- Hospices Civils de Lyon77
- Johns Hopkins University69
- University of Minnesota63
- Washington University School of Medicine63
Where studies are running
- California655
- Massachusetts304
- New York295
- Florida267
- Texas267
- Maryland248
- Arizona209
- Alabama205
- Illinois183
- Pennsylvania175
Recruiting studies11,934 total
- NCT04722939Recruiting
Testing brain function outcomes after ICU kidney failure treatment
This trial studies how treating severe kidney injury in the ICU may affect patients’ brain and thinking function over time. It compares measurements of brain activity and function after starting kidney replacement therapy.
Kingston, OntarioAges 18 years+ - NCT05063955Recruiting
Study muscle changes in people with heart failure
This study looks at the reasons for age-related muscle loss (sarcopenia) in people with heart failure. It may help researchers understand what is causing muscle weakness and how it could be treated in the future.
Aarhus NAges 18–90 - NCT07859397Recruiting
Pain relief options for knee ligament surgery
This study compares two nerve-block approaches to see which provides better pain relief after knee ligament reconstruction surgery. If you are having this surgery, joining could help manage your pain more effectively.
AnkaraAges 18–65 - NCT03655782Recruiting
Retraining brain pathways to improve memory after mild brain injury
This study tests a computer-based brain training program that may help improve memory and thinking skills in people who have had a mild traumatic brain injury or concussion. The training involves watching moving stripes on a screen and using arrow keys to respond, which is designed to retrain brain pathways.
San Diego, CaliforniaAges 18–60 - NCT07863011Recruiting
Low-dose brain radiation for mild Alzheimer's disease
This study tests a low dose of radiation to the whole brain combined with an experimental drug to see if it can slow down the effects of mild Alzheimer's disease. It aims to help people with mild dementia think more clearly and keep their daily abilities for as long as possible.
Cheonan, Chungcheongnam-doAges 60–85 - NCT07863232Recruiting
Melatonin and nutrition for fibromyalgia pain relief
This study tests whether taking melatonin, a sleep and pain hormone, along with special nutrition supplements, can help reduce fibromyalgia pain. It may offer a new way to manage symptoms.
LarissaAges 18 years+ - NCT07854327Recruiting
Lymphatic drainage treatment for Alzheimer's disease
This trial tests a procedure to improve the brain's waste-clearing system, which may slow the effects of Alzheimer's disease. It's a new approach that aims to help the brain work better.
Siena, TuscanyAges Any age - NCT07864142Recruiting
Early screening for spinal cord defects in pregnancy
This study looks at whether early ultrasound measurements and blood tests in the first trimester can help detect open neural tube defects, which are problems with the baby's spine or brain. It may improve early detection and care for pregnant women.
StrasbourgAges 18 years+ - NCT06291532Enrolling by invitation
Virtual reality system for autism and intellectual disability
This study tests whether a virtual reality system is easy and usable for people with autism and intellectual disability. It might help improve daily skills in a fun, engaging way.
Messina, MessinaAges 6–40 - NCT07860580Recruiting
Blood markers in children with congenital hearing loss
This study looks at certain substances in the blood of children with congenital hearing loss (hearing loss present from birth) to see if they are different from children with normal hearing. It may help doctors understand why hearing loss happens and could lead to better treatments.
SanliurfaAges Up to 17 years - NCT07861230Recruiting
Tongue study in children with sleep-disordered breathing
This study looks at the tongue in children aged 4 to 17 who have sleep-disordered breathing (like snoring or pauses in breathing during sleep). The goal is to understand how the tongue might be related to these sleep problems, which could lead to better treatments.
LiègeAges 4–17 - NCT07863310Recruiting
Epilepsy stigma education with nurse support
This trial tests a nurse-led program to help people with epilepsy understand and cope with stigma, which may improve their quality of life and self-esteem.
MalatyaAges 18 years+ - NCT07378800Recruiting
Improving care interactions in assisted living for memory loss
This study looks at ways to make daily interactions with staff in assisted living more positive for people with memory loss. It may help improve quality of life and well-being.
Columbia, MarylandAges 55 years+ - NCT07855419Recruiting
Muscle loss and steroid injections for lumbar spinal stenosis
This study looks at whether the amount of muscle loss (sarcopenia) affects how well steroid injections into the spine work for people with lumbar spinal stenosis, a condition that causes back and leg pain from narrowing of the spinal canal.
Istanbul, IstanbulAges 50–75 - NCT07865403Recruiting
Online psychological support for fibromyalgia
This trial tests an online program that combines psychological support with physical rehabilitation to help manage fibromyalgia symptoms. It aims to improve well-being and daily functioning from home.
Rome, RomeAges 18–70 - NCT04863612Recruiting
SBRT for spinal tumors with possible spinal cord pressure
This study looks at treating spinal metastases (spread to the spine from a solid cancer) using SBRT, a focused type of radiation. It aims to control tumor growth and relieve or prevent spinal cord compression, sometimes alongside surgery.
Leuven, Vlaams BrabantAges 18–99 - NCT03998020Recruiting
Sleep study group for people with long-lasting excessive sleepiness
This study is building a long-term group of people with chronic excessive sleepiness (hypersomnolence) so researchers can better understand rare sleep disorders and related biology. It involves sleep-focused assessments and questionnaires, and you may or may not be on treatment for sleep problems.
MontpellierAges 6 years+ - NCT04942041Recruiting
Thrombectomy for large stroke blockages at low-volume centers
This study tests whether using a procedure called mechanical thrombectomy at smaller stroke centers can improve outcomes after a large-vessel stroke. It may help people who have a major artery blockage get timely treatment, with measured effects on complications and survival.
Kristiansand, AgderAges 18–100 - NCT05089604RecruitingPhase 4
Compare two tacrolimus forms to reduce tremors after liver transplant
This study compares immediate-release versus extended-release tacrolimus (an anti-rejection medicine) to see if one form causes fewer tremors after a first liver transplant. It may help you and your care team choose the best form if tremors are a problem while your body adjusts after transplant.
Vancouver, British ColumbiaAges 18 years+ - NCT02346396Recruiting
At-home brain stimulation trial for long-lasting nerve pain
This study tests a device that delivers mild electrical stimulation to the brain from home to help reduce chronic nerve pain. It focuses on people whose pain has not improved enough despite stable pain medicines.
BronAges 18–80 - NCT05896592Recruiting
Ablation versus changing pacing settings for slow heartbeats
This study compares a procedure called cardioneuroablation with staying on permanent pacing in people who have symptoms from a slow heart rate. It aims to see which approach works better and is safer for reducing symptoms related to sinus node or heart conduction problems.
Radom, Masovian VoivodeshipAges 18–65 - NCT04623463Recruiting
Exercise and how it affects sleep apnea severity
This study looks at whether regular physical activity can make obstructive sleep apnea (OSA) less severe. It focuses on people who are not yet receiving OSA treatment and checks changes in severity over time.
GrenobleAges 18–80 - NCT06014723Recruiting
Balloon angioplasty for recent minor stroke or TIA
This study tests a balloon procedure to open a narrowed artery in the brain to prevent further strokes. It is for people who recently had a mild stroke or high-risk TIA from a significant blockage.
Changchun, JilinAges 30–80 - NCT06065527Recruiting
Future planning for caregivers of people with disabilities
This study helps family caregivers plan for the future and improve their well-being while caring for a loved one with an intellectual disability. It's done online or on a device, so you can take part from home.
New Hyde Park, New YorkAges 18 years+
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 11,934 recruiting neurology studies from the U.S. registry right now, out of 18,325 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.