Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,407 recruiting studies in this area right now.
By phase
- Not applicable9,740
- Phase 2781
- Phase 1578
- Phase 3536
- Phase 4343
- Phase 1/Phase 2306
- Phase 2/Phase 3123
Top conditions
- Stroke841
- Parkinson Disease429
- Multiple Sclerosis345
- Alzheimer Disease341
- Dementia226
- Ischemic Stroke201
- Epilepsy197
- Obstructive Sleep Apnea156
- Spinal Cord Injuries154
- Insomnia152
- Traumatic Brain Injury150
- Sarcopenia149
- Acute Ischemic Stroke137
- Cerebral Palsy131
- Mild Cognitive Impairment129
- Migraine114
- Pain Management113
- Amyotrophic Lateral Sclerosis108
Leading sponsors
- Beijing Tiantan Hospital133
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic98
- Xuanwu Hospital, Beijing93
- VA Office of Research and Development92
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California681
- Massachusetts299
- New York292
- Florida273
- Texas268
- Maryland246
- Arizona214
- Alabama210
- Illinois189
- Pennsylvania175
Recruiting studies12,405 total
- NCT06381115Recruiting
SleepWell24 app for new CPAP users
This study tests a smartphone app called SleepWell24 to help people with newly diagnosed sleep apnea stick with their CPAP therapy and improve their quality of life.
Scottsdale, ArizonaAges 18 years+ - NCT07588659Recruiting
Weighted Blanket for ADHD Sleep Problems in Children
This study tests whether a weighted blanket—a blanket filled with small beads that provides gentle pressure—helps children with ADHD sleep better. Researchers want to see if this simple tool can improve sleep when used alongside regular sleep habits.
FrederiksbergAges 5–12 - NCT07391605RecruitingPhase 2
Descartes-08 for treatment-resistant myositis
This trial tests a new treatment called Descartes-08 for people with dermatomyositis or antisynthetase syndrome whose disease hasn't responded well to standard therapies. It aims to see if this treatment can help control muscle and skin symptoms.
Orange, CaliforniaAges 18 years+ - NCT06990997Recruiting
Do aphasia ID cards help service workers understand?
This study tests if identification cards that explain aphasia help service workers better understand people with aphasia. Service workers will listen to or read messages and answer questions.
Springfield, MassachusettsAges 18–59 - NCT04261478Recruiting
Treatment for stroke caused by blocked brain and neck arteries
This trial studies a procedure that opens blocked blood vessels in and behind the brain during a stroke, sometimes after standard clot-thinning medicine. It may help people who have brain tissue that can still be saved and a major blockage in both the neck and brain arteries.
Montreal, QuebecAges 18 years+ - NCT07392450RecruitingPhase 2
Study of TAK-755 for adults with acute ischemic stroke
This trial tests if TAK-755 can help people who have had a moderate to severe stroke within the last 24 hours. It aims to see if the drug can improve recovery by protecting brain tissue that is still salvageable.
Scottsdale, ArizonaAges 18 years+ - NCT04649242RecruitingPhase 3
Migraine pain relief study for kids and teens
This trial studies a medicine for stopping a migraine attack in children and teens. It may help families understand which treatment works best during acute (during-attack) migraine pain.
Birmingham, AlabamaAges 6–17 - NCT06014905RecruitingPhase 1
Better MRI imaging for meningioma
This trial tests a new type of MRI scan that may help see meningioma brain tumors more clearly. It is a short imaging study for people who plan to have surgery or monitoring.
San Francisco, CaliforniaAges 18 years+ - NCT07033494RecruitingPhase 2
Study of MK-2214 for early Alzheimer's disease
This trial tests an experimental medicine called MK-2214 for people with early Alzheimer's (mild cognitive impairment or mild dementia). The goal is to see if it can slow memory and thinking problems.
Irvine, CaliforniaAges 50–85 - NCT05617014Enrolling by invitation
ADNI4 study for early Alzheimer’s with brain imaging tests
This study enrolls people with no memory impairment, mild memory problems, or mild Alzheimer’s dementia to test how brain scans and cognitive tests relate to Alzheimer’s disease. It may help by contributing to better early diagnosis and by letting you see whether you fit into the study’s imaging and blood-test pathway.
Birmingham, AlabamaAges 55–90 - NCT06255782RecruitingPhase 3
Gene therapy study for baby boys with severe OTC deficiency
This trial tests a gene therapy called ECUR-506 for baby boys under 9 months old with a severe form of OTC deficiency. The goal is to see if it can help their bodies process ammonia better, reducing the need for a strict protein-restricted diet and medications.
Los Angeles, CaliforniaAges 1 day–7 months - NCT07223203RecruitingPhase 3
Study of nucresiran for hereditary nerve condition (hATTR-PN)
This trial tests a new medicine called nucresiran for people with a rare genetic nerve condition (hATTR-PN). The goal is to see if it can slow down or improve nerve damage.
Aurora, ColoradoAges 18–85 - NCT07609719RecruitingPhase 4
Switch to under-the-skin ocrelizumab for multiple sclerosis
This trial tests a new way of taking Ocrelizumab as a shot under the skin, for people with MS who are already on a similar treatment and want to switch. The goal is to see if switching is safe and works well.
GuaynaboAges 18–65 - NCT07638267Recruiting
Comparing different intensity levels of yoga for insomnia
This study compares the effects of moderate-intensity versus low-intensity yoga on sleep in adults with insomnia. If you have insomnia and are not already doing much yoga, you may find this study helpful for improving your sleep.
Orlando, FloridaAges 18–40 - NCT07762170RecruitingPhase 4
Steroid injections for back and pelvic pain
This study is testing how well and how safely steroid injections work for different types of back pain. If you join, you'll receive the injection as part of your care and fill out surveys about your pain and ability to do daily activities before and after.
Thornhill, OntarioAges 18 years+ - NCT07027475Recruiting
Acute treatment and long-term monitoring for adults with meningitis
This study looks at the best way to treat meningitis in adults right away and then checks how people recover over time. It aims to improve care and recovery for patients.
Fortaleza, CearáAges 18 years+ - NCT05477927RecruitingPhase 1
CAR-T therapy for cancers spread to lining of lungs, belly, or brain
This trial tests an experimental CAR-T cell treatment that targets proteins on cancer cells that have spread to the lining of the lungs, belly, or brain. It may help people whose cancer has not responded to standard treatments.
Chengdu, SichuanAges 18–80 - NCT07761936RecruitingPhase 3
Safinamide for Parkinson's disease pain
This study tests whether safinamide, an add-on medication for Parkinson's disease, can reduce chronic pain in people who also experience motor fluctuations (times when symptoms return between doses). It aims to see if this treatment can improve pain and quality of life.
Verona, VenetoAges 18 years+ - NCT07764198Recruiting
Gabor visual training for adult lazy eye
This study tests a home-based visual training program that uses special patterns to help improve vision in adults with amblyopia, often called lazy eye. It may offer a new way to gain visual improvement.
ShanghaiAges 18–39 - NCT07160634RecruitingPhase 3
Gene therapy for ambulant males with Duchenne muscular dystrophy
This trial tests a new gene therapy called SGT-003 in boys and men with Duchenne muscular dystrophy who are still able to walk. The treatment aims to deliver a working version of the dystrophin gene to help muscle cells produce the protein they are missing.
Little Rock, ArkansasAges 7–11 - NCT05704361RecruitingPhase 1
Study of an experimental drug for multiple sclerosis
This study tests an experimental drug called RO7121932 in people with multiple sclerosis. The goal is to see how safe it is and how the body processes it. It might help by offering a new way to manage the condition.
Stanford, CaliforniaAges 18–65 - NCT06687733RecruitingPhase 1/Phase 2
Gene therapy for phenylketonuria
This trial tests a new gene therapy, NGGT002, which delivers a healthy gene to help people with phenylketonuria (PKU) manage their phenylalanine levels. It may reduce the need for strict diet control.
Bengbu, AnhuiAges 18–55 - NCT07764172Recruiting
Sarcopenia in acute ischemic stroke
This study looks at muscle loss (sarcopenia) in people who have had an acute ischemic stroke. It aims to understand how muscle wasting affects recovery, which may help improve care for stroke patients.
MoscowAges 50 years+ - NCT07763392Recruiting
Normal cognitive test scores for adults
This study is testing a voice-controlled digital platform to measure normal memory and thinking abilities in healthy adults. By participating, you would help create a baseline of normal scores that doctors can use to compare against when assessing people with thinking problems.
Carlsbad, CaliforniaAges 18–100
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,407 recruiting neurology studies from the U.S. registry right now, out of 19,231 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.