Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,425 recruiting studies in this area right now.
By phase
- Not applicable9,762
- Phase 2784
- Phase 1574
- Phase 3535
- Phase 4342
- Phase 1/Phase 2305
- Phase 2/Phase 3123
Top conditions
- Stroke845
- Parkinson Disease426
- Multiple Sclerosis343
- Alzheimer Disease341
- Dementia226
- Ischemic Stroke200
- Epilepsy197
- Obstructive Sleep Apnea155
- Spinal Cord Injuries154
- Insomnia153
- Sarcopenia149
- Traumatic Brain Injury149
- Acute Ischemic Stroke139
- Cerebral Palsy131
- Mild Cognitive Impairment129
- Pain Management114
- Migraine112
- Amyotrophic Lateral Sclerosis108
Leading sponsors
- Beijing Tiantan Hospital133
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing94
- VA Office of Research and Development93
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California678
- Massachusetts300
- New York292
- Florida275
- Texas267
- Maryland245
- Arizona213
- Alabama211
- Illinois189
- Pennsylvania178
Recruiting studies12,423 total
- NCT06036706Recruiting
Radiation types and thinking skills for skull base meningioma
This study compares different radiation methods for treating a slow-growing, non-cancerous brain tumor at the base of the skull. It aims to see which approach best protects memory and thinking abilities.
CaenAges 20–65 - NCT06038929Recruiting
Vagus nerve stimulation and stomach function study
This study looks at how vagus nerve stimulation (VNS) affects how your stomach works, like emptying and stretching. It may help researchers understand the digestive side effects of VNS in people who already have a VNS device for epilepsy or depression.
Minneapolis, MinnesotaAges 18 years+ - NCT06039176Recruiting
Learning from the HeartMate 3 device
This study looks at information from the HeartMate 3 LVAD device to learn more about how it works and what it can tell us about the future. It may help people with advanced heart failure who need this specific device.
San Francisco, CaliforniaAges 18–100 - NCT06039332Recruiting
Comparing ways to fit a bone conduction implant
This study compares two ways to adjust a BONEBRIDGE bone conduction implant for people with hearing loss. It aims to find which fitting strategy gives better sound quality and daily benefit.
MadridAges 18 years+ - NCT06039709RecruitingPhase 1
Sound wave therapy for recurrent glioblastoma
This trial tests a new treatment called sonodynamic therapy that uses sound waves and a special drug to target brain tumors that have come back. It aims to see if this approach is safe and can shrink tumors in people who are eligible for surgery.
Charlottesville, VirginiaAges 18–80 - NCT06040567Recruiting
Polyneuropathy, Impairments and Physical Activity Study
This study looks at how polyneuropathy (nerve damage) affects your daily physical activity and overall function. It aims to understand the link between nerve damage and movement, which could help improve care.
CopenhagenAges 18–100 - NCT06040619Recruiting
Therapy Together for children with cerebral palsy
This trial tests a therapy program called Therapy Together for children at risk for or diagnosed with cerebral palsy who have trouble using one hand. It aims to help them use their affected hand and arm more effectively.
Frisco, TexasAges 3 months–5.9 years - NCT06040892Recruiting
Hearing in noise for children with two cochlear implants
This study tests if wearing two cochlear implants helps children hear speech better in noisy places. The goal is to improve listening skills in everyday situations like classrooms or playgrounds.
LyonAges 7–17 - NCT06040697Recruiting
Testing a wireless thermal device for shunt checks
This study tests a new wireless device that uses heat to check if your shunt is working properly. Researchers want to make sure it's easy to use and comfortable for patients and caregivers.
Chicago, IllinoisAges 5–80 - NCT06041334Recruiting
Spina Bifida blood vessel study
This trial studies blood vessels in people with spina bifida using safe, non-invasive methods. It aims to better understand how the condition affects the body over time.
Rennes, CHU de RennesAges 6 years+ - NCT06041659Recruiting
Brain network changes during moyamoya bypass surgery
This study uses MRI scans to watch how brain networks work while you are asleep during moyamoya bypass surgery. It may help doctors understand how the brain adjusts after the procedure.
Beijing, Beijing MunicipalityAges 18–65 - NCT06041997Recruiting
Limiting smartphone use for headache relief
This trial tests whether reducing smartphone use can help treat primary headaches (migraines or tension headaches) in adults. If you get headaches that aren't caused by another medical condition, this study might be a good fit.
New Delhi, National Capital Territory of DelhiAges 18 years+ - NCT06042140Recruiting
Umbilical cord patch for spina bifida repair before birth
This study tests whether a patch made from donated umbilical cord can help repair spina bifida in the womb using a minimally invasive fetoscopic approach. If successful, it may reduce the need for more invasive open fetal surgery.
Houston, TexasAges 18 years+ - NCT06042946Recruiting
Surgery for spinal cord tumors that spread from other cancers
This trial is for adults who have a specific type of spinal cord tumor that has spread from another cancer. It looks at how well a surgery called microsurgical resection works to remove the tumor and what happens to patients before and after the procedure.
Sankt GallenAges 18 years+ - NCT06043440RecruitingPhase 2
Oxygen therapy for sleep apnea in Down syndrome
This study tests whether oxygen therapy can help children with Down syndrome who have sleep apnea. It compares oxygen treatment to no treatment to see if it improves breathing during sleep and thinking skills.
Los Angeles, CaliforniaAges 5–18 - NCT06044168Recruiting
Nutritional supplement for muscle growth in cerebral palsy
This study tests whether a nutritional supplement can help build muscle in children with spastic cerebral palsy. It may be a good fit if you have trouble with walking and have not had certain treatments recently.
Leuven, Vlaams-BrabantAges 4–10 - NCT06044584Recruiting
AI tool for tracking pain after injury or nerve pain
This study tests a smartphone-based tool that uses artificial intelligence to track your pain and how it affects your daily life. It may help you and your doctor better understand your pain over time.
Pietra Ligure, SavonaAges 18–80 - NCT06044662Recruiting
Predicting nerve damage with blood markers
This study looks at certain markers in the blood that may help predict how polyneuropathy (nerve damage) will progress. It involves physical tests, and results could help doctors better understand the condition.
CopenhagenAges 18 years+ - NCT06045013RecruitingPhase 3
Dextrose injection vs. dextrose with steroid for carpal tunnel
This study tests whether adding a common steroid (methylprednisolone) to a dextrose (sugar water) injection works better than dextrose alone for carpal tunnel syndrome. Both treatments are injected into the wrist to reduce pain and numbness.
KninAges 18–80 - NCT06045156Recruiting
Tirofiban after clot-busting for stroke
This trial tests whether giving tirofiban (a blood thinner) shortly after the standard clot-busting drug tenecteplase can improve recovery from a moderate stroke. It is for people who have had a stroke within the last few hours and do not have certain risk factors like irregular heart rhythm or recent bleeding.
Changchun, JilinAges 18 years+ - NCT06045455Recruiting
CT scan to tell stroke from stroke mimics
This trial is testing whether a special type of CT scan can help doctors tell the difference between a stroke and other conditions that look like a stroke (called stroke mimics). If you have a sudden neurologic symptom within the past 24 hours, this study may help get a clearer diagnosis.
Ostrava, Moravian-Silesian RegionAges 18 years+ - NCT06045936RecruitingPhase 4
Nerve block for phantom limb pain
This study tests whether a nerve block in the remaining part of your leg can help reduce phantom limb pain or pain in the residual limb. It is for people who have had an amputation more than a year ago and still have pain despite trying other treatments.
Mankato, MinnesotaAges 18 years+ - NCT06047353Recruiting
Helping people with sleep apnea try PAP therapy for the first time
This study tests whether health advocates can help people with moderate-to-severe sleep apnea start using a PAP machine. If you've never used a PAP or other sleep apnea treatment before, this trial may help you get support and guidance.
Miami, FloridaAges 18–100 - NCT06047496RecruitingEarly Phase 1
Time-restricted eating for sleep apnea
This study tests whether limiting your eating to a shorter daily window can improve health in people with untreated moderate to severe sleep apnea. You would eat all your meals within a set number of hours each day while tracking your progress on your smartphone.
La Jolla, CaliforniaAges 18–70
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,425 recruiting neurology studies from the U.S. registry right now, out of 19,436 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.