Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,425 recruiting studies in this area right now.
By phase
- Not applicable9,762
- Phase 2784
- Phase 1574
- Phase 3535
- Phase 4342
- Phase 1/Phase 2305
- Phase 2/Phase 3123
Top conditions
- Stroke845
- Parkinson Disease426
- Multiple Sclerosis343
- Alzheimer Disease341
- Dementia226
- Ischemic Stroke200
- Epilepsy197
- Obstructive Sleep Apnea155
- Spinal Cord Injuries154
- Insomnia153
- Sarcopenia149
- Traumatic Brain Injury149
- Acute Ischemic Stroke139
- Cerebral Palsy131
- Mild Cognitive Impairment129
- Pain Management114
- Migraine112
- Amyotrophic Lateral Sclerosis108
Leading sponsors
- Beijing Tiantan Hospital133
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing94
- VA Office of Research and Development93
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California678
- Massachusetts300
- New York292
- Florida275
- Texas267
- Maryland245
- Arizona213
- Alabama211
- Illinois189
- Pennsylvania178
Recruiting studies12,423 total
- NCT06048094RecruitingPhase 1
PET scan study for brain metastases treated with radiosurgery
This trial tests a special PET scan (18F-fluciclovine) to see how well it shows brain metastases after stereotactic radiosurgery (a precise form of radiation). It may help doctors better understand treatment effects.
Miami, FloridaAges 18 years+ - NCT06047782Recruiting
MRI study of atrial scarring and stroke risk
This study uses a special heart MRI to look for scarring in the upper chambers of the heart (atria) that might cause hidden atrial fibrillation after a stroke with no known cause. It may help explain why the stroke happened and guide future treatment.
DijonAges 18 years+ - NCT06047717Recruiting
Virtual reality navigation study for stroke survivors
This study uses virtual reality to understand how vision loss from a stroke affects navigation. You may help researchers learn more by wearing a VR headset and doing simple tasks.
Rochester, New YorkAges 21–75 - NCT06048159Recruiting
Brain stimulation to improve memory after stroke-related aphasia
This study tests a safe, non-invasive brain stimulation called tACS to see if it can help improve short-term memory for sounds and words in people who have trouble speaking after a stroke. If you have aphasia from a left-brain stroke, this treatment might help your brain relearn how to remember and repeat what you hear.
Milwaukee, WisconsinAges 18 years+ - NCT06048419Recruiting
Testing GO MOVE program for kids with one-sided weakness
This study tests a home-based online program called GO MOVE for children and teens who have weakness on one side of their body from cerebral palsy or another early brain injury. The program is done on your own device and aims to improve arm and hand use through fun, guided activities.
Frisco, TexasAges 3–17 - NCT06048523Recruiting
Study of genetic brain diseases
This study follows people with a confirmed genetic nerve or brain disease over time, collecting blood and sometimes spinal fluid samples to learn more about the condition. It may help researchers understand how the disease progresses.
BordeauxAges 6 years+ - NCT06048796Recruiting
Early stopping of sedation after cardiac arrest with normal EEG
This study is testing whether it is safe to stop sedation and temperature management early in cardiac arrest patients who have a normal-looking brain wave test (EEG). If you qualify, you would stop sedation sooner than usual, which may help you wake up faster.
Arnhem, GelderlandAges 18 years+ - NCT06049459Recruiting
Virtual Reality Games for Lazy Eye in Kids
This study tests if playing virtual reality games can help improve vision in children with lazy eye (amblyopia). It may be an option for kids who haven't fully improved with glasses or patching.
Columbus, OhioAges 5–17 - NCT06050369Recruiting
Study of repetitive behaviors in OCD and Tourette syndrome
This study looks at repetitive behaviors in people with OCD or Tourette syndrome. It uses MRI scans to understand the brain, and aims to help improve treatments for these conditions.
CréteilAges 15–65 - NCT06050668RecruitingPhase 2
Amino acid supplement study for broken hip in older adults
This study tests whether giving extra essential amino acids (building blocks of protein) to older adults hospitalized with a broken femur (thigh bone) can improve their recovery. If you are 65 or older, broke your femur from a simple fall, and are having surgery to fix it, you may be able to join.
Iowa City, IowaAges 65 years+ - NCT06051227RecruitingPhase 3
Pain relief after injury: fentanyl vs. esketamine
This trial compares two strong pain medicines—fentanyl and esketamine—to see which works better for treating pain right after a traumatic injury. You would receive the medicine by spray in your nose or through a vein before going to the hospital.
AmsterdamAges 18 years+ - NCT06051240RecruitingPhase 2
Lithium to prevent thinking problems after brain radiation
This study tests if the drug lithium can help prevent memory and thinking problems that sometimes happen after brain radiation for a brain tumor. You may qualify if you are under 18 when treated and had radiation within the last 7 years.
Solna, Stockholm CountyAges 5 years+ - NCT06052280Recruiting
Parkinson's physical therapy: in clinic vs. at home
This study compares in-person physical therapy with a home exercise program you can do using a computer or tablet. It aims to see if remote therapy works as well as coming to the clinic, which could make it easier for you to get the help you need.
CuneoAges 18 years+ - NCT06052163RecruitingPhase 2
Testing bumetanide for early Alzheimer's disease
This study tests whether a water pill called bumetanide can help people with early Alzheimer's disease. It involves taking the study drug, having MRI scans, and doing memory tests to see if it slows down symptoms.
Stanford, CaliforniaAges 50–85 - NCT06052605Recruiting
Healthy aging study for older adults with epilepsy
This study looks at healthy aging in people with epilepsy. You will fill out a survey to help researchers understand your experiences and needs.
Cleveland, OhioAges 55–90 - NCT06052397Recruiting
Sleep and body clock markers for confusion after surgery
This trial tests whether sleep patterns and body clock signals can help predict confusion after major orthopedic surgery. You would wear a watch that tracks movement to see how your sleep relates to recovery.
Boston, MassachusettsAges 70 years+ - NCT06052969Recruiting
Pulse NanoMED MicroBeads after clot removal for stroke
This trial tests a new treatment called Pulse NanoMED MicroBeads for people who still have a blocked brain artery after a standard clot removal procedure (mechanical thrombectomy). The goal is to see if these tiny beads can clear the remaining blockage and improve blood flow to the brain.
Columbia, South CarolinaAges 18–85 - NCT06053229Recruiting
Massage therapy for leg muscle health during immobilization
This trial examines if percussive massage can help maintain leg muscle mass and strength when your leg is immobilized (e.g., in a cast). It aims to see if this therapy could reduce muscle loss during periods of disuse.
Provo, UtahAges 18–50 - NCT06053190Recruiting
Clear speech and memory in older adults
This study is testing whether listening to clear speech (slow, precise) helps older adults understand and remember sentences better. If you're between 60 and 90, right-handed, and a native English speaker, this trial may help you or your loved one learn more about how to improve communication as you age.
Salt Lake City, UtahAges 60–90 - NCT06053320Recruiting
Stroke rehab study using brain stimulation and movement training
This study tests whether a type of brain stimulation combined with movement training can help people who have had a right-side stroke improve their arm and hand function. It also includes healthy adults to compare results.
Atlanta, GeorgiaAges 18–90 - NCT06053671Recruiting
Understanding genetics in focal epilepsy brain tissue
This study is looking at brain tissue from people with a specific type of epilepsy (Focal Cortical Dysplasia Type II). The goal is to understand what causes the seizures and how they develop, which may help improve future treatments.
LondonAges Any age - NCT06053619Recruiting
Virtual reality walking rehab for stroke patients who cannot walk
This trial tests whether adding virtual reality to robot-assisted walking therapy helps people who have had a stroke and cannot walk. It is for patients who had a first stroke in the past 15 days to 6 months.
LimogesAges 35–75 - NCT06054295Recruiting
Twin study of childhood brain tumors
This study looks at genetic differences between identical twins where only one twin has a childhood brain or spinal cord tumor. It helps researchers understand why some children get cancer and others don't.
Minneapolis, MinnesotaAges Up to 18 years - NCT06054828Recruiting
Modified ICU program to prevent confusion
This trial tests a special program for people in the ICU who are on a breathing machine. The program aims to prevent confusion and help patients recover better.
Taipei, National Taiwan UniversityAges 18 years+
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,425 recruiting neurology studies from the U.S. registry right now, out of 19,436 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.