Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,407 recruiting studies in this area right now.
By phase
- Not applicable9,740
- Phase 2781
- Phase 1578
- Phase 3536
- Phase 4343
- Phase 1/Phase 2306
- Phase 2/Phase 3123
Top conditions
- Stroke841
- Parkinson Disease429
- Multiple Sclerosis345
- Alzheimer Disease341
- Dementia226
- Ischemic Stroke201
- Epilepsy197
- Obstructive Sleep Apnea156
- Spinal Cord Injuries154
- Insomnia152
- Traumatic Brain Injury150
- Sarcopenia149
- Acute Ischemic Stroke137
- Cerebral Palsy131
- Mild Cognitive Impairment129
- Migraine114
- Pain Management113
- Amyotrophic Lateral Sclerosis108
Leading sponsors
- Beijing Tiantan Hospital133
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic98
- Xuanwu Hospital, Beijing93
- VA Office of Research and Development92
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California681
- Massachusetts299
- New York292
- Florida273
- Texas268
- Maryland246
- Arizona214
- Alabama210
- Illinois189
- Pennsylvania175
Recruiting studies12,405 total
- NCT07150806RecruitingPhase 1/Phase 2
RYZ101 for progressive or recurrent meningioma
This trial is testing an investigational drug, RYZ101, for people with a type of brain tumor called meningioma that has grown back or not responded to other treatments. The goal is to see if RYZ101 can help stop the tumor from growing, and to check its safety. It might be an option if you have already had surgery or radiation.
Columbus, OhioAges 18 years+ - NCT05124392Recruiting
Observational study of biomarkers in people at risk for prion disease
This study looks for early signs of prion disease in people who are at risk, using blood tests, spinal fluid, and thinking tests. It hopes to find ways to diagnose and track the disease earlier.
Charlestown, MassachusettsAges 18–85 - NCT06359041RecruitingPhase 1/Phase 2
CABA-201 cell therapy for generalized myasthenia gravis
This trial tests a new cell therapy called CABA-201 for people with generalized myasthenia gravis. It aims to reset the immune system to reduce muscle weakness and improve daily functioning.
Orange, CaliforniaAges 18–70 - NCT07577336Recruiting
Portable MRI for brain injury in children
This study tests whether a small, portable MRI machine can take pictures of the brain at the bedside for children with brain injuries from lack of oxygen or blood flow. It may help doctors see the injury sooner and guide care without moving the child.
Kansas City, MissouriAges Up to 17 years - NCT07762872Recruiting
Satralizumab during early NMOSD attacks
This study looks at how well the medication satralizumab works when started early during an NMOSD attack, along with standard treatments. The aim is to see if adding this drug can help reduce the impact of the attack and improve outcomes.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07762365Recruiting
Brain stimulation with reading help for children with dyslexia
This study tests whether pairing a gentle brain stimulation technique with structured reading instruction can improve reading skills in children with dyslexia. It aims to find a new way to support reading development.
Boston, MassachusettsAges 7–17 - NCT07763522Enrolling by invitation
Measuring ankle strength in people with herniated disc weakness
This study tests a new way to measure ankle strength in people who have weakness from a herniated disc in the lower back. The goal is to confirm the measurement tool works well for tracking such weakness.
Helsinki, UusimaaAges 18–65 - NCT07371624RecruitingPhase 1/Phase 2
Study of B2065 for recent ischemic stroke
This trial tests an investigational drug called B2065 for people who have had a recent ischemic stroke (a stroke caused by a blockage in a blood vessel in the brain). The goal is to see if it is safe and if it might help improve recovery when given within 36 hours of stroke symptoms starting.
BeijingAges 18–75 - NCT07761026Recruiting
Living with myasthenia gravis: share your experience
This 10-year study collects information from people with myasthenia gravis to learn more about the condition and improve care. By sharing your experiences, you can help researchers understand what daily life is like and shape future treatments.
Framingham, MassachusettsAges 18 years+ - NCT05476939RecruitingPhase 3
BIOMEDE 2.0 trial for DIPG and similar brainstem gliomas
This phase 3 study tests targeted treatments (ONC201 or everolimus) for children with DIPG or similar diffuse midline brain tumors, based on the tumor’s genetic markers. It aims to improve outcomes by matching treatment to the tumor biology and comparing approaches in a randomized way.
AarhusAges 6 months+ - NCT05669703Recruiting
Tracking mood and activity patterns in bipolar disorder families
This study watches how a person’s mood and movement change over time, and how those patterns relate to bipolar disorder. It may help researchers better understand the condition in families and potentially improve future care.
Bethesda, MarylandAges 8–70 - NCT07762144Enrolling by invitation
Recovery after cardiac arrest
This trial collects health information from people who have survived a cardiac arrest (when the heart stops) and have been brought back to life. The information may help doctors improve care and recovery after this event.
Beijing, Beijing MunicipalityAges Any age - NCT07163299Enrolling by invitationPhase 1/Phase 2
Cooling artery treatment with magnesium for stroke clot removal
This trial tests adding a cooled magnesium solution directly into the brain artery during standard clot removal to see if it helps limit brain damage and improve recovery. The magnesium and cooling aim to protect brain tissue while the clot is being taken out.
Xuzhou, JiangsuAges 18–80 - NCT06808984RecruitingPhase 2
Testing a new drug for agitation in Alzheimer's disease
This trial tests an investigational drug called BMS-986368 to see if it can safely reduce agitation in people with Alzheimer's disease. You may be able to join if you have Alzheimer's with confirmed biomarkers and experience agitation that has been going on for at least 4 weeks.
Homewood, AlabamaAges 55–90 - NCT07595185Enrolling by invitation
Brain Stimulation to Improve Sleep in Chronic Insomnia
This study tests whether accelerated repetitive transcranial magnetic stimulation (rTMS)—a non-invasive brain stimulation technique—can improve sleep architecture and quality in people with chronic insomnia. The treatment may help you fall asleep faster and sleep longer without medication.
San Francisco, CaliforniaAges 18–85 - NCT04462770RecruitingPhase 3
Clemizole trial for children and adults with Dravet syndrome
This Phase 3 study tests EPX-100 (clemizole) to help reduce seizures in people with Dravet syndrome whose seizures are not fully controlled by current anti-seizure medicines. You may consider this study if your Dravet diagnosis is confirmed and your medical situation fits the specific rules about medicines and seizure causes.
Birmingham, AlabamaAges 2 years+ - NCT07500090RecruitingPhase 3
Study of HBS-301 for idiopathic hypersomnia
This trial tests a new medication, HBS-301, in people with idiopathic hypersomnia (a condition causing excessive sleepiness without clear cause). It aims to see if the drug improves wakefulness and is safe.
Birmingham, AlabamaAges 18 years+ - NCT05946577Recruiting
Links tinnitus and hearing changes after head and neck cancer treatment
This study looks at how tinnitus (ringing in the ears) and hearing problems may develop after radiotherapy alone or with certain chemotherapy for high-risk head and neck cancer. The goal is to better understand who is more likely to experience these side effects.
ParisAges 18 years+ - NCT07563881RecruitingPhase 3
Testing RAP-219 for Focal Seizure Control in Adults
This study tests whether a new medication called RAP-219 can help adults with focal seizures (seizures that start in one area of the brain) control their seizures better. You would take this medication alongside your current seizure drugs for about 12 weeks.
Palmdale, CaliforniaAges 18–75 - NCT07656857Recruiting
Flexible brain sensor study for epilepsy surgery
This trial tests a new flexible brain sensor to help guide surgery for people with drug-resistant focal epilepsy. It aims to find exactly where seizures start so surgeons can remove that area safely.
Beijing, Beijing MunicipalityAges 3–60 - NCT07578324Recruiting
TENS to reduce pain during prostate biopsy
This study tests whether TENS (a gentle electrical stimulation applied to the skin) can help reduce pain when combined with numbing medicine during a prostate biopsy procedure. The goal is to see if this may make the biopsy more comfortable for patients.
Gdansk, Pomeranian VoivodeshipAges 40 years+ - NCT03153670Recruiting
Brain scan study for people with deep brain stimulators
This study uses a 3‑tesla MRI (a type of detailed brain scan) in people who have deep brain stimulation (DBS) electrodes. The goal is to improve understanding of how the brain works; the scan is not meant to provide direct treatment benefit.
Toronto, OntarioAges 18–85 - NCT07559006Recruiting
Shoulder Pain After Stroke and Its Effects on Arm Function
This study looks at how shoulder pain affects arm movement, balance, and daily activities in people who've had a stroke. Researchers want to understand the connection between shoulder pain and physical recovery after stroke.
Kütahya, KütahyaAges 18–80 - NCT07459647RecruitingPhase 2
Long-term study of ML-007C-MA for schizophrenia
This trial tests a new drug, ML-007C-MA, for adults with schizophrenia who may benefit from ongoing treatment. It aims to see how safe and effective the drug is over a longer period.
Little Rock, ArkansasAges 18–65
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,407 recruiting neurology studies from the U.S. registry right now, out of 19,231 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.