Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 11,934 recruiting studies in this area right now.
By phase
- Not applicable9,337
- Phase 2764
- Phase 1555
- Phase 3514
- Phase 4340
- Phase 1/Phase 2299
- Phase 2/Phase 3125
Top conditions
- Stroke797
- Parkinson Disease395
- Alzheimer Disease337
- Multiple Sclerosis330
- Dementia224
- Epilepsy192
- Ischemic Stroke190
- Insomnia159
- Traumatic Brain Injury151
- Obstructive Sleep Apnea142
- Spinal Cord Injuries142
- Acute Ischemic Stroke139
- Sarcopenia135
- Mild Cognitive Impairment126
- Cerebral Palsy119
- Pain Management113
- Migraine107
- Fibromyalgia105
Leading sponsors
- Beijing Tiantan Hospital124
- Assistance Publique - Hôpitaux de Paris109
- Riphah International University105
- Mayo Clinic98
- VA Office of Research and Development92
- Xuanwu Hospital, Beijing89
- Hospices Civils de Lyon77
- Johns Hopkins University69
- University of Minnesota63
- Washington University School of Medicine63
Where studies are running
- California655
- Massachusetts304
- New York295
- Florida267
- Texas267
- Maryland248
- Arizona209
- Alabama205
- Illinois183
- Pennsylvania175
Recruiting studies11,934 total
- NCT05475262Recruiting
Inpatient sleep study using white noise
This study looks at whether playing white noise helps people sleep better while they are in the hospital. If you’re an adult admitted for several days, you may be able to join.
La Jolla, CaliforniaAges 18 years+ - NCT05935709Recruiting
Danish database study for GCA or PMR
This study builds and uses a Danish database for people diagnosed with giant cell arteritis (GCA) or polymyalgia rheumatica (PMR). It may help doctors learn more about these conditions over time and improve care.
AarhusAges 50 years+ - NCT06222255Recruiting
Transanal irrigation for sleep issues after rectal cancer surgery
This trial tests if a special irrigation technique can improve sleep problems caused by low anterior resection syndrome (LARS) after rectal cancer surgery. It may help people who have ongoing bowel symptoms that disrupt sleep.
Seoul, Jongro-guAges 19–80 - NCT05306834Recruiting
Study to slow memory decline by targeting hidden small brain vessel disease
This trial looks at how to slow cognitive decline and early dementia in people with a specific kind of “silent” blood vessel damage in the brain seen on scans. It may help identify whether targeting this hidden condition can protect thinking and memory over time.
BordeauxAges 60–88 - NCT04623593Recruiting
Study of cost and value of neck disc surgery
This study looks at how cost-effective (good value for the money) anterior neck disc surgery is for people with nerve or spinal cord symptoms. If you need this type of operation, it may help doctors better choose treatments and plan healthcare resources.
Maastricht, LimburgAges 18 years+ - NCT05855603Recruiting
Pacemaker versus nerve ablation for fainting due to slow heart rate
This trial studies treatments for a type of fainting caused by the body’s reflex slowing the heart. It compares a permanent pacemaker with a procedure called cardiac nerve ablation to see which helps prevent fainting and improves quality of life.
Sant Joan d'Alacant, AlicanteAges 40 years+ - NCT07869238Recruiting
Safety study of NMS-01 for mild to moderate Alzheimer's disease
This trial tests a new treatment called NMS-01 for people with mild to moderate Alzheimer's disease. It aims to see if it's safe and may help with symptoms.
Seoul, SeodaemunAges 50–85 - NCT07864389Recruiting
Monitoring brain aneurysms that have not burst
This study looks at a new way to check on brain aneurysms that have not burst and are not causing symptoms. It may help doctors decide if or when treatment is needed, using regular imaging instead of surgery.
NantesAges 18 years+ - NCT05424978Recruiting
Standardized green-channel treatment for acute stroke care
This study tests a structured, fast way of treating people who have a new ischemic stroke (a stroke caused by a blocked blood vessel). It may help because it focuses on getting the right stroke treatments quickly and consistently.
Xi'an, ShaanxiAges 18–100 - NCT07866768Recruiting
Ultrasound treatment to clear brain waste in early memory loss
This study tests a low-intensity ultrasound treatment aimed at helping the brain clear out harmful protein buildup linked to Alzheimer's disease. It is for people 65 and older with mild cognitive impairment (slight but noticeable memory problems) and a positive test for amyloid, a protein in the brain.
San Francisco, CaliforniaAges 65 years+ - NCT07872202Recruiting
Parkinson's rehabilitation and independence study
This study looks at how rehabilitation can help people with Parkinson's disease become more independent and improve their symptoms. It aims to see if specific exercises can make daily tasks easier and improve quality of life.
OlomoucAges 50–80 - NCT07860840Recruiting
Visual training before robot-assisted walking for stroke survivors
This study tests whether a special visual training program before using a walking robot can improve walking recovery in people who have had a stroke or similar brain injury within the last 6 months and have trouble sensing their affected side. If you join, you might get this extra visual practice to help your brain relearn movement.
Negrar, ItalyAges 18–80 - NCT06178120Recruiting
Study of disease progression in women with X-linked adrenoleukodystrophy
This study follows women with a genetic condition called X-linked adrenoleukodystrophy (ALD) over time to see how the disease progresses. It includes annual check-ups and MRI scans of the brain and spinal cord to monitor changes.
ParisAges 18 years+ - NCT06212609Recruiting
Personalized brain stimulation for kids with hard-to-control epilepsy
This trial tests a personalized brain stimulation method (transcranial electrical stimulation) to reduce seizures in children with hard-to-control partial epilepsy. It aims to find the best stimulation spot and settings for each patient by using advanced brain scans.
AmiensAges 1–18 - NCT04474106Recruiting
Shock wave therapy for new spinal cord injuries
This study tests whether extracorporeal shock wave therapy (non-surgical shock waves delivered from outside the body) can improve movement and sensation after a recent spinal cord injury. It may help people recover motor (movement) and sensory (feeling) function within months after injury.
Innsbruck, TyrolAges 18–99 - NCT05649670Recruiting
Compare starting stroke clot-busting before vs after hospital
This study tests whether starting clot-busting treatment by the emergency team before hospital arrival works better than starting it after you reach the hospital. It may help doctors improve speed and outcomes after an acute stroke.
GarchesAges 18 years+ - NCT06237075Recruiting
Brain imaging and mild stimulation for nerve pain
This study uses brain imaging (fMRI) and a mild electrical stimulation (tDCS) to understand and potentially help nerve pain. You may be eligible if you have nerve pain or numbness from peripheral neuropathy or a stroke, and can avoid caffeine/alcohol before visits.
TaipeiAges 20–90 - NCT04534777Recruiting
Tests ways to predict recovery after brain injury
This study looks at different ways to predict how people with severe disorders of consciousness might recover after a brain injury. It may help doctors better estimate prognosis and improve care planning.
ParisAges 18–80 - NCT04574037Recruiting
Predicting arm recovery after stroke
This study tries to predict how well your arm movement may improve after a stroke. It uses brain and/or nerve testing (like MRI and TMS) and could help doctors plan the best rehabilitation for you.
ParisAges 18 years+ - NCT06241521Recruiting
Myasthenia gravis patient registry in China
This study creates a registry to collect information about people with myasthenia gravis in China. By joining, you help researchers learn more about the condition and how it affects different people.
Beijing, Beijing MunicipalityAges Any age - NCT03838042RecruitingPhase 1/Phase 2
Testing nivolumab plus entinostat for high-risk childhood cancers
This trial studies whether nivolumab (an immune therapy) plus entinostat (an epigenetic medicine) can help children and teens with high-risk cancers that have come back, worsened, or did not respond to prior treatment. It also looks at specific tumor “biomarkers” to group patients and guide how the study is run.
Randwick, New South WalesAges 2–21 - NCT05204459Recruiting
MRI and eye-scan study for MS and related conditions
This trial uses brain MRI and eye imaging tests to study research markers in people with multiple sclerosis (MS) and related neurologic conditions. It may help researchers better understand these diseases and how they change over time.
Los Angeles, CaliforniaAges 18 years+ - NCT06243718Recruiting
Surgery for paralyzed diaphragm nerve
This trial looks at how patients feel and recover after surgery to fix the nerve that controls the diaphragm. It aims to learn about people's experiences to improve care for diaphragmatic paralysis.
Red Bank, New JerseyAges 18–70 - NCT03409003Recruiting
Carbaglu monitoring study for suspected NAGS deficiency
This study follows people who have (or might have) NAGS deficiency and who are taking Carbaglu to treat it. The goal is to better track safety and health outcomes over time.
Washington D.C., District of ColumbiaAges Any age
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 11,934 recruiting neurology studies from the U.S. registry right now, out of 18,325 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.