Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,435 recruiting studies in this area right now.
By phase
- Not applicable9,772
- Phase 2786
- Phase 1573
- Phase 3535
- Phase 4342
- Phase 1/Phase 2304
- Phase 2/Phase 3123
Top conditions
- Stroke846
- Parkinson Disease426
- Multiple Sclerosis343
- Alzheimer Disease341
- Dementia226
- Ischemic Stroke200
- Epilepsy196
- Obstructive Sleep Apnea155
- Spinal Cord Injuries154
- Insomnia153
- Sarcopenia149
- Traumatic Brain Injury149
- Acute Ischemic Stroke139
- Cerebral Palsy131
- Mild Cognitive Impairment129
- Pain Management114
- Migraine112
- Amyotrophic Lateral Sclerosis108
Leading sponsors
- Beijing Tiantan Hospital133
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing94
- VA Office of Research and Development93
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California680
- Massachusetts300
- New York291
- Florida274
- Texas268
- Maryland245
- Arizona214
- Alabama209
- Illinois190
- Pennsylvania177
Recruiting studies12,433 total
- NCT06316752Recruiting
Natural history study of sialidosis type I
This study follows people with sialidosis type I over time to understand how the condition progresses. Participants will have regular exams, blood draws, brain scans, and eye tests.
Taipei, TaipeiAges 12–80 - NCT06316778Recruiting
Pelvic floor training for women with myotonic dystrophy
This study tests whether pelvic floor muscle training (exercises to strengthen the muscles that control urine flow) can help women with myotonic dystrophy type 1 who have bladder leakage. It's a gentle, non-surgical approach that may improve quality of life.
Jonquière, QuebecAges 18 years+ - NCT06317701Recruiting
Nerve stimulation for sleep apnea in overweight adults
This trial tests a nerve stimulation treatment for obstructive sleep apnea in people who are overweight and cannot tolerate CPAP. It focuses on how the treatment affects metabolism and weight.
Chicago, IllinoisAges 18 years+ - NCT06317870Recruiting
Nerve block vs spinal morphine for hip surgery pain
This trial compares two types of pain relief after a hip replacement: a nerve block (injecting numbing medicine near the hip) versus a small dose of morphine given through a spinal needle. It aims to find out which option works better with fewer side effects.
Lausanne, Canton of VaudAges 18 years+ - NCT06318260RecruitingPhase 1/Phase 2
Dobutamine for heart failure in wild-type ATTR amyloidosis
This trial tests whether dobutamine, a heart-strengthening medicine, can improve blood flow and symptoms in people with a specific type of amyloidosis that affects the heart and who are already on water pills.
AarhusAges 65 years+ - NCT06318585Recruiting
Building a database for motor neuron disease research
This study collects information from people with ALS or other motor neuron diseases to better understand how these conditions vary. By joining a database, you help researchers find patterns that could improve care.
Milan, MIAges 18 years+ - NCT06318598Recruiting
ALS and motor neuron disease biomarker study
This study looks for biological markers in people with ALS or other motor neuron diseases to better understand the different types of the disease. It may help find new ways to treat or manage these conditions.
Milan, MIAges 18 years+ - NCT06319482Recruiting
Testing a new sleep apnea therapy device
This study tests a new proactive therapy for people recently diagnosed with moderate or severe sleep apnea. It aims to see how well patients stick with the treatment outside of a sleep lab.
Halifax, Nova ScotiaAges 18–70 - NCT06319846RecruitingPhase 3
Tirofiban for recent mild stroke or TIA with narrowed brain artery
This trial tests the drug tirofiban (a blood thinner) to prevent another stroke in people who have had a mild stroke or high-risk TIA and have a narrowed artery in the brain. It must be started within 24 hours of symptoms.
Harbin, HeilongjiangAges 40 years+ - NCT06320106Recruiting
Navigating abilities in children with cerebral palsy
This study compares how children with cerebral palsy and their peers navigate spaces. It aims to understand differences in orientation and movement skills.
Bosisio Parini, LeccoAges 13 years+ - NCT06320132Recruiting
Study on brain bleed recovery in the ICU
This study looks at how patients recover after a sudden, non-traumatic brain bleed. It aims to learn more about their brain function and daily living skills over time.
Milan, MIAges 18 years+ - NCT06320639Recruiting
Driving simulator study for people with memory or thinking problems
This study uses a driving simulator to see how people with mild cognitive problems or dementia perform while driving. If you have a driver's license and are still driving or recently stopped, you may be able to join.
VilleurbanneAges 50–95 - NCT06320431RecruitingPhase 3
Clot-busting drug for disabling stroke within 4.5 hours
This trial tests a clot-busting drug called tenecteplase for people having a disabling ischemic stroke (a clot blocking blood flow to the brain). It aims to see if the drug can help improve recovery when given within 4.5 hours of symptoms starting.
Sydney, BarangarooAges 18 years+ - NCT06321341RecruitingPhase 4
Testing Vespireit for chronic dizziness from autonomic dysfunction
This trial tests a new medication called Vespireit (prolonged-release buspirone) for people with chronic dizziness caused by a problem with the autonomic nervous system. The study aims to see if the drug helps reduce dizziness and improve quality of life.
BryanskAges 18–65 - NCT06321588Recruiting
Autoimmune dementia: predicting antibodies in new cognitive decline
This study looks for certain antibodies that might be causing your new memory or thinking problems. It aims to find patterns that could help diagnose autoimmune dementia earlier.
Bologna, BolognaAges 40–90 - NCT06321965Recruiting
Study of SMA in Children on SMN-Boosting Therapies
This study is looking for children and teens with spinal muscular atrophy (SMA) who are already on a treatment like Spinraza, Evrysdi, or Zolgensma. The goal is to understand different forms of SMA and how the treatment affects them over time.
Bron, RhoneAges birth–16 years - NCT06321822Recruiting
Genetic diagnosis and personalized medicine for epilepsy patients
This study aims to find genetic causes of epilepsy and use that information to personalize your care. It involves analyzing your DNA to look for gene changes that may be linked to your seizures.
MilanAges Any age - NCT06322030Recruiting
Weight loss and exercise for stroke survivors
This study tests whether a weight loss and exercise program can help veterans who had a stroke at least 6 months ago and have some leg weakness. It aims to improve mobility and overall health.
Charleston, South CarolinaAges 40–80 - NCT06322953RecruitingPhase 3
Timing to restart blood thinners after head injury bleeding
This trial looks at when it is safest to restart blood thinners after a traumatic brain bleed. It compares restarting at 4 weeks versus 8 weeks in people on blood thinners before their injury.
Plymouth, DevonAges 18 years+ - NCT06322667Recruiting
Study of lecanemab in early Alzheimer's disease
This study tracks the real-world experience of people with early Alzheimer's disease who are already taking lecanemab. It aims to better understand how the medication works and its safety in everyday medical practice.
HiroshimaAges 18 years+ - NCT06322810Recruiting
Pain relief methods for open heart surgery: ESP vs PIFB
This study compares two ways to manage pain after open-heart surgery. It looks at using an injection near the spine (ESP block) versus a needle placed through the chest wall (PIFB) to help reduce pain and the need for strong pain medicines.
Taichung, TaiwanAges 18 years+ - NCT06323434Recruiting
Spinal fluid leaks in chronic subdural hematoma
This study looks for spinal fluid leaks in people with chronic subdural hematoma (a slow buildup of blood on the brain). It uses MRI to find a possible cause, which could help improve treatment.
Freiburg im Breisgau, Baden-WurttembergAges 18 years+ - NCT06323278Recruiting
Thinking and memory training for Parkinson's disease
This study tests whether a thinking-and-memory training program (cognitive stimulation) can help people with Parkinson's who have mild memory or thinking problems, but not dementia. You must not have had deep brain stimulation surgery.
MilanAges 18–80 - NCT06323330Recruiting
Music therapy for speech recovery after stroke
This study tests if music therapy can help people with speech problems after a stroke. It is designed for those who had a stroke within the past year and have trouble speaking fluently (non-fluent aphasia).
New Delhi, National Capital Territory of DelhiAges 18–99
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,435 recruiting neurology studies from the U.S. registry right now, out of 19,491 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.