Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,435 recruiting studies in this area right now.
By phase
- Not applicable9,772
- Phase 2786
- Phase 1573
- Phase 3535
- Phase 4342
- Phase 1/Phase 2304
- Phase 2/Phase 3123
Top conditions
- Stroke846
- Parkinson Disease426
- Multiple Sclerosis343
- Alzheimer Disease341
- Dementia226
- Ischemic Stroke200
- Epilepsy196
- Obstructive Sleep Apnea155
- Spinal Cord Injuries154
- Insomnia153
- Sarcopenia149
- Traumatic Brain Injury149
- Acute Ischemic Stroke139
- Cerebral Palsy131
- Mild Cognitive Impairment129
- Pain Management114
- Migraine112
- Amyotrophic Lateral Sclerosis108
Leading sponsors
- Beijing Tiantan Hospital133
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing94
- VA Office of Research and Development93
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California680
- Massachusetts300
- New York291
- Florida274
- Texas268
- Maryland245
- Arizona214
- Alabama209
- Illinois190
- Pennsylvania177
Recruiting studies12,433 total
- NCT06308367RecruitingPhase 2
Betaine for syringomyelia when other treatments failed
This trial tests if betaine can help people with syringomyelia who cannot have or did not benefit from standard surgery. You must be able to swallow tablets and have a life expectancy over 12 months.
Beijing, Beijing MunicipalityAges 18–80 - NCT06308952RecruitingPhase 4
Atorvastatin before flow diverter for brain aneurysms
This trial tests whether taking atorvastatin before a flow diverter procedure can prevent strokes or other brain events in people with unruptured brain aneurysms. It may help reduce complications from the treatment.
Guangzhou, GuangdongAges 18–75 - NCT06308978RecruitingPhase 1
Study of FT819 for B-cell autoimmune diseases
This trial tests a new cell therapy, FT819, for people with certain autoimmune diseases like lupus, vasculitis, myositis, or scleroderma that haven't improved with at least two previous treatments. The goal is to see if it can help control the disease.
Beverly Hills, CaliforniaAges 12–70 - NCT06309251Recruiting
Ketogenic diet for children with epilepsy or other conditions
This trial studies how well a ketogenic diet works for children with hard-to-treat epilepsy or certain other diseases. It aims to see if the diet improves quality of life.
Milan, MIAges Up to 18 years - NCT06309264Recruiting
Comparing ways to fit hearing aids for blast-exposed Veterans
This study compares two different ways of fitting hearing aids for Veterans who were exposed to blasts and now have hearing difficulties. The goal is to see which method works better for improving hearing and understanding speech.
Loma Linda, CaliforniaAges 18–60 - NCT06309602Recruiting
Testing a free water protocol for stroke or trauma patients
This trial studies whether allowing patients who are on thickened liquids to also have sips of plain water is safe. It may help people who are recovering from stroke or injury and can protect their own airway.
Loveland, ColoradoAges 18 years+ - NCT06310278Recruiting
Normal ear movement data collection study
This study collects information on how the eardrum moves in people with normal hearing. It helps doctors understand what 'normal' looks like so they can better detect hearing problems.
Halifax, Nova ScotiaAges 18 years+ - NCT06311604Recruiting
Inhaled sedation safety for head trauma patients
This trial tests a new way to give sedation through a breathing mask (isoflurane gas) to people with severe head injuries. It aims to see if this method is safe and may help when IV sedatives alone are not enough.
Grenoble, Choisir Une RégionAges 18 years+ - NCT06312046Recruiting
Thinking and Movement in MS: A Balance Study
This study tests how thinking and movement interact in people with MS who have some balance problems. It aims to find ways to improve daily function.
Stockholm, Stockholm CountyAges 18–65 - NCT06312644Recruiting
Study of Ultomiris safety during pregnancy
This study looks at the safety of the medication Ultomiris when taken during pregnancy or breastfeeding. If you are pregnant and currently taking Ultomiris for an approved condition, this research will help gather information on how it affects you and your baby.
Boston, MassachusettsAges Any age - NCT06312631Recruiting
Home glove helps stroke survivors use their arm
This study tests a home-use glove (SaeboGlove®) that may help people who had a stroke grip and hold objects with their hand. It looks at how using the glove affects arm function and what factors help people stick with the program.
ToulouseAges 18–90 - NCT06312956Recruiting
Sleep Apnea and Ventilotherapy: A Study Before and After Treatment
This trial studies how sleep apnea affects the body and brain before and after starting treatment with a breathing device (ventilotherapy). It aims to understand the benefits of early treatment for people with obstructive sleep apnea.
Piancavallo, VCOAges 20–60 - NCT06313515Recruiting
Spinal cord stimulation with arm bike for heart health in SCI
This study tests if adding spinal cord stimulation to arm bike exercise can improve heart and blood vessel health in people with chronic spinal cord injury. You would come to the clinic up to 3 times a week for up to 6 months.
Seattle, WashingtonAges 21–65 - NCT06313866Recruiting
Herbal sniffing therapy plus acupuncture for stroke-related thinking problems
This trial tests if combining traditional Chinese herbal sniffing therapy with electroacupuncture can improve memory and thinking after a stroke. It may help people who are still in the early recovery phase.
Hangzhou, ZhejiangAges Up to 70 years - NCT06313853Recruiting
Communication support for older adults with dementia and cancer
This study tests a communication coaching session to help older adults with both dementia and cancer talk with their family and doctors about treatment decisions. The goal is to make sure your wishes and needs are heard.
Rochester, New YorkAges 65 years+ - NCT06313944Recruiting
German registry of Alzheimer's treated with sound wave therapy
This trial is a registry that collects information about people with Alzheimer's disease who receive a treatment called transcranial pulse stimulation (TPS), which uses gentle sound waves to stimulate the brain. The goal is to track safety and how well it works over time.
Potsdam, BrandenburgAges 18–85 - NCT06314477Recruiting
CPAP treatment for severe uncontrolled asthma with sleep apnea
This trial tests if CPAP (a mask that helps you breathe at night) can improve asthma control in people who have both severe uncontrolled asthma and sleep apnea (a condition where breathing stops and starts during sleep). You should not have been hospitalized for asthma in the last month.
Barcelona, SpainAges 18 years+ - NCT06314607Recruiting
Genetic study of brain lesions
This trial looks at the genetic and molecular features of brain lesions to better understand them. It may help find new ways to diagnose or treat these conditions.
ParisAges 18 years+ - NCT06314594Recruiting
Personalized care for teens with scoliosis
This study tests a personalized health management plan for teens with mild to moderate scoliosis (spine curve less than 45 degrees). It aims to help prevent the curve from getting worse and improve treatment through a special online platform.
Hangzhou, ZhejiangAges 3–18 - NCT06314776Recruiting
Vibration therapy for walking in children with cerebral palsy
This study tests whether a special vibrating platform can help improve walking in children with cerebral palsy. It may help strengthen muscles and coordination.
AlmeríaAges 2–11 - NCT06315010RecruitingPhase 2
Repotrectinib for ROS1-positive lung cancer with brain spread
This clinical trial tests a new targeted therapy pill (repotrectinib) for people with ROS1-positive lung cancer that has spread to the brain. The pill is designed to enter the brain and attack cancer cells that other targeted treatments may not reach well.
GrazAges 18 years+ - NCT06316232RecruitingPhase 4
DBS and Levodopa for Freezing of Gait in Parkinson's
This trial tests whether increasing the dose of levodopa or adjusting deep brain stimulation (DBS) can help reduce freezing of gait in people with Parkinson's who already have good control of other symptoms. It aims to find the best way to manage this common and frustrating problem.
BolognaAges 18–80 - NCT06316076RecruitingPhase 1
CD19 CAR-T cell therapy for autoimmune diseases
This trial tests a new type of immune cell therapy (CAR-T cells targeting CD19) for people with autoimmune diseases that haven't improved with standard treatments. The goal is to see if it is safe and can help control the disease.
ShanghaiAges 18–65 - NCT06316557Recruiting
TMS for memory and thinking after stroke
This trial tests if a gentle brain stimulation treatment (TMS) can help improve memory and thinking after a recent stroke. It is for people who had their first stroke within the last two weeks and have mild cognitive difficulties.
BeijingAges 18 years+
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,435 recruiting neurology studies from the U.S. registry right now, out of 19,491 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.