Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,435 recruiting studies in this area right now.
By phase
- Not applicable9,772
- Phase 2786
- Phase 1573
- Phase 3535
- Phase 4342
- Phase 1/Phase 2304
- Phase 2/Phase 3123
Top conditions
- Stroke846
- Parkinson Disease426
- Multiple Sclerosis343
- Alzheimer Disease341
- Dementia226
- Ischemic Stroke200
- Epilepsy196
- Obstructive Sleep Apnea155
- Spinal Cord Injuries154
- Insomnia153
- Sarcopenia149
- Traumatic Brain Injury149
- Acute Ischemic Stroke139
- Cerebral Palsy131
- Mild Cognitive Impairment129
- Pain Management114
- Migraine112
- Amyotrophic Lateral Sclerosis108
Leading sponsors
- Beijing Tiantan Hospital133
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing94
- VA Office of Research and Development93
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California680
- Massachusetts300
- New York291
- Florida274
- Texas268
- Maryland245
- Arizona214
- Alabama209
- Illinois190
- Pennsylvania177
Recruiting studies12,433 total
- NCT06324149Recruiting
Frailty and aging conditions in chronic diseases
This study looks at how frailty affects the course of chronic diseases and how chronic diseases affect frailty. It may help understand aging-related conditions better.
MilanAges 18–100 - NCT06324188Recruiting
Early ablation for afib to prevent stroke in high-risk patients
This trial tests whether an early procedure (catheter ablation) for atrial fibrillation (AF) can prevent strokes in people with a high risk of stroke. The goal is to see if this treatment is safer and more effective than standard care for patients with other health conditions.
Multiple LocationsAges 18 years+ - NCT06324422Recruiting
Exercise for Parkinson's fatigue
This trial tests if a structured exercise program can reduce fatigue in people with Parkinson's disease. It may help you feel less tired and improve daily function.
Aarhus, Central JutlandAges 40 years+ - NCT06324955Recruiting
Using words during mask anesthesia in children
This study looks at whether simple spoken words during the process of falling asleep with a breathing mask can help children ages 5–10 have a better experience. The goal is to make anesthesia induction less scary for kids.
Boston, MassachusettsAges 5–10 - NCT06325488Recruiting
Kidney Health Study in Fabry Disease
This study uses MRI scans to look at how Fabry disease affects the kidneys, including scarring, swelling, and oxygen levels. It may help researchers understand kidney problems better and find new ways to monitor the disease.
CopenhagenAges 18 years+ - NCT06325852Recruiting
New brain stimulation for Essential Tremor
This study tests a new way to use Deep Brain Stimulation (a device that sends tiny electrical pulses to parts of the brain controlling movement) for people with Essential Tremor. It is for those whose current stimulator is no longer working well, or who need a stimulator for the first time.
Toronto, OntarioAges 18–85 - NCT06401538RecruitingPhase 2
BMB-101 for absence epilepsy and DEE
This trial tests a new drug called BMB-101 for people with absence epilepsy (including Jeavons syndrome) or developmental epileptic encephalopathies (DEE) like Dravet or Lennox-Gastaut. It aims to see if the drug can reduce seizure frequency and is safe.
Randwick, New South WalesAges 18–65 - NCT06474390Recruiting
Testing a home sleep monitor for accuracy
This study tests a new home sleep monitoring device (TipTraQ) to see how well it works compared to the standard overnight sleep test done in a lab. It is for people who are already scheduled for a sleep study at Duke University Hospital.
Taipei, TaipeiAges 20 years+ - NCT07511049RecruitingPhase 2
Brincidofovir for PML brain infection
This pilot study tests an IV medicine called brincidofovir for people with PML, a serious brain infection. The goal is to see if it can stop the virus from causing more damage.
Bethesda, MarylandAges 18–99 - NCT05334927Recruiting
Headache disorder registry for teens and adults with primary headaches
This study is a headache disorder registry that enrolls people with common, “primary” headache types such as migraine or tension headache, including some with medication-overuse headaches. It collects information to better understand these conditions and who they affect.
Anqing, AnhuiAges 12 years+ - NCT06174727Recruiting
Registry of flow diverter and disruptor treatments
This study is a registry that collects information from patients who have had a brain aneurysm treated with a special type of device called a flow diverter or flow disruptor. By joining, you help doctors learn more about how well these treatments work over time and which patients benefit most.
Coral Gables, FloridaAges 18 years+ - NCT05234866Recruiting
Test for “paradoxical lucidity” in severe late-stage dementia
This trial studies whether “paradoxical lucidity” can happen in people with very advanced dementia. It may help doctors understand changes in awareness in late-stage illness and improve how care is provided.
New York, New YorkAges 18 years+ - NCT05350215RecruitingPhase 1/Phase 2
Testing atomoxetine and DAW2022 for obstructive sleep apnea severity
This study tests whether atomoxetine and DAW2022 can improve how severe obstructive sleep apnea is. It may help by changing breathing patterns during sleep, measured through physiology tests.
Boston, MassachusettsAges 21–70 - NCT04588233Recruiting
Melatonin study for teens with sleep trouble
This study tests whether melatonin can help teens (ages 13–17) who have trouble sleeping. You may be able to join if you’ve never taken melatonin before and your sleep issue seems to be behavior-related rather than caused by another medical sleep problem.
Loma Linda, CaliforniaAges 13–17 - NCT07178704Recruiting
Genes and metabolism after weight loss surgery
This study looks at how your genes and metabolism affect changes in body composition after weight loss surgery. It aims to understand why some people lose more weight or gain muscle differently than others.
Galveston, TexasAges 18–65 - NCT07694986RecruitingPhase 2
Vaccine therapy for breast cancer that has spread to the brain and spinal cord
This trial tests a new type of vaccine (dendritic cells) injected directly into the spinal fluid, combined with either trastuzumab (if your breast cancer is HER2-positive) or nivolumab (if your breast cancer is HER2-negative). The goal is to see if this combination can better control breast cancer that has spread to the lining of the brain and spinal cord.
Tampa, FloridaAges 18 years+ - NCT07362862Recruiting
Electrical muscle stimulation to prevent ICU weakness
This trial tests a wearable device that uses mild electrical pulses to stimulate leg muscles, helping prevent muscle weakness in ICU patients with severe infections. It may help you recover strength faster and avoid long-term disability.
Rochester, MinnesotaAges 18–85 - NCT07202208Recruiting
Preventing confusion after hip fracture surgery
This trial tests a special care plan (the 'Delirium Zero Protocol') to help prevent confusion (delirium) after hip fracture surgery. It is for people over 65 who are having hip fracture surgery and have a family member or caregiver who can be involved.
Manises, ValenciaAges 65 years+ - NCT06450158Recruiting
Robot-assisted training for children with cerebral palsy
This trial tests if robot-assisted training helps improve motor skills in children with cerebral palsy who can walk without major aids. It compares them to children without brain injuries.
Fort Worth, TexasAges 6–18 - NCT07695233Recruiting
Ultrasound brain stimulation for freezing of gait in Parkinson's
This trial tests a noninvasive ultrasound treatment targeting a brain area called the pedunculopontine nucleus to help reduce freezing of gait (a sudden inability to walk) in Parkinson's disease. If you have Parkinson's and experience freezing, you may be eligible to try this new approach.
Toronto, OntarioAges 18–90 - NCT05975398Recruiting
Study of severe spontaneous brain bleeding in China
This study looks at people with a severe type of brain bleed that happens on its own (not from an injury). It compares different treatments to find the best way to help patients recover.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06560242Recruiting
Tracking early sound perception in Fragile X syndrome
This study uses safe brain monitoring (fNIRS and EEG) to see how infants with Fragile X syndrome process sounds compared to other infants. The goal is to find early signs of hearing or perception issues.
Cincinnati, OhioAges 6 months–2.2 years - NCT07303959Recruiting
Sleep treatment for teens after a hospital stay
This study tests a sleep program called Sleepio to help teens who have been in the hospital for suicide risk and also have trouble sleeping. The goal is to see if improving sleep can help them feel better and stay safer.
Piscataway, New JerseyAges 14–18 - NCT06438471RecruitingPhase 1
Study of a new drug for nerve pain after spinal cord injury
This trial tests an experimental pill for people with spinal cord injury who have long-term nerve pain. It aims to see if the drug can reduce pain and be safe.
Augusta, GeorgiaAges 18 years+
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,435 recruiting neurology studies from the U.S. registry right now, out of 19,491 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.