Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,432 recruiting studies in this area right now.
By phase
- Not applicable9,770
- Phase 2785
- Phase 1574
- Phase 3537
- Phase 4342
- Phase 1/Phase 2303
- Phase 2/Phase 3121
Top conditions
- Stroke846
- Parkinson Disease424
- Multiple Sclerosis343
- Alzheimer Disease340
- Dementia226
- Ischemic Stroke200
- Epilepsy196
- Obstructive Sleep Apnea155
- Insomnia153
- Spinal Cord Injuries153
- Sarcopenia149
- Traumatic Brain Injury149
- Acute Ischemic Stroke141
- Cerebral Palsy131
- Mild Cognitive Impairment129
- Pain Management114
- Migraine112
- Amyotrophic Lateral Sclerosis107
Leading sponsors
- Beijing Tiantan Hospital134
- Riphah International University126
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing94
- VA Office of Research and Development93
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California674
- Massachusetts300
- New York291
- Florida274
- Texas267
- Maryland245
- Arizona214
- Alabama209
- Illinois190
- Pennsylvania177
Recruiting studies12,430 total
- NCT06368323Recruiting
Choir singing for people with aphasia after stroke
This study tests if singing in a community choir can help people with aphasia (trouble speaking or understanding language) after a stroke. It focuses on those who have had a stroke at least 6 months ago and who speak English or French at home.
Tampa, FloridaAges 18 years+ - NCT06368492Recruiting
Psilocybin for fibromyalgia pain
This trial tests whether psilocybin, a substance found in certain mushrooms, can help reduce pain in people with fibromyalgia. You would receive the drug and be monitored closely to see if it improves your pain levels.
Maastricht, LimburgAges 18–65 - NCT06369051Recruiting
Helping young stroke survivors start their own business
This trial tests a program to help young adults who had a stroke and are currently unemployed start their own business. It aims to understand if support can help them return to work through self-employment.
Hong KongAges 18–64 - NCT06369766Recruiting
Eye scans to find retinal markers in neuroinflammatory diseases
This study uses advanced eye scans (OCT and retinal vessel imaging) to look for patterns in the retina that might be different in people with Multiple Sclerosis and other neuroinflammatory diseases. The goal is to find markers that could help doctors better understand and monitor these conditions.
BaselAges 18 years+ - NCT06370104Recruiting
Online therapy for recent suicidal thoughts or behavior
This study tests a remote therapy program for people who have had suicidal thoughts or behaviors in the past month. It aims to provide timely support without needing to see a therapist in person.
Amsterdam, South HollandAges 16 years+ - NCT06370520Recruiting
Teen emotions screening after mild brain injury
This study screens teens aged 11 to 17 for emotional and mental health problems after a mild traumatic brain injury (mTBI, also called concussion or minor head injury). The goal is to find out if the hospital screening helps identify teens who may need extra support.
Sacramento, CaliforniaAges 11–17 - NCT06371040RecruitingPhase 1
CAR-T cell therapy for severe myasthenia gravis
This trial is testing a new type of cell therapy called CAR-T that targets two proteins (CD19 and BCMA) on certain immune cells. It aims to help people with severe myasthenia gravis that has not improved with standard treatments.
Xi'an, ShaanxiAges 18–80 - NCT06370962Recruiting
Sleep study for children with cystic fibrosis on Kaftrio-Kalydeco
This study looks at sleep and daily activity rhythms in children with cystic fibrosis who are taking a medication called Kaftrio-Kalydeco. It aims to understand if the medication affects sleep patterns and how to improve them.
BronAges 2–17 - NCT06371937Recruiting
Heart and blood vessel disease biobank study
This study creates a collection of skin cells (turned into stem cells in a lab) from people with various heart and blood vessel conditions. It aims to find new ways to understand and treat these diseases.
London, OntarioAges 18–80 - NCT06372587Recruiting
Next-generation Alzheimer's treatment study
This study tests a new treatment for people with probable Alzheimer's disease. It aims to see if the treatment is safe and effective for patients between 18 and 80 years old.
RomaAges 18–80 - NCT06372847Recruiting
Sleep apnea nerve stimulation study
This trial tests a nerve-stimulation implant for sleep apnea when other treatments haven't worked. It may help if you have moderate to severe apnea, a BMI under 32, and have tried CPAP and a mouth device without success.
Edegem, AntwerpenAges 18 years+ - NCT06372821RecruitingPhase 1
Study of NIO752 for Alzheimer's disease
This study tests an experimental drug called NIO752 to see if it can reduce the production of tau protein, which is linked to Alzheimer's disease. Researchers will measure how the drug affects tau in your body using a special technique called SILK.
St Louis, MissouriAges 21–80 - NCT06373718Recruiting
How sleep affects emotions in insomnia with low mood
This study explores how improving sleep might help regulate emotions in people who have both insomnia and mild depressive symptoms. You could help researchers understand the link between sleep and mood.
Palo Alto, CaliforniaAges 18–65 - NCT06374108Recruiting
Resistance training and walking in multiple sclerosis
This study tests whether resistance training (like lifting weights) can improve how your brain and muscles communicate, and whether that helps your walking. It's designed for people with MS who have some walking difficulties.
Aarhus, Central JutlandAges 18 years+ - NCT06374238Recruiting
Peer Support for Young People with Sickle Cell Pain
This study is testing a peer support program for teens and young adults (ages 16–30) with sickle cell disease who have chronic pain. You'll connect with a trained peer supporter through your smartphone to learn pain coping skills and get support.
Mobile, AlabamaAges 16–30 - NCT06374277Recruiting
Pharmacy Coaching to Help After Hospital Stay
This study tests a program where a pharmacist helps you manage your medications after you leave the hospital. It is for people with long-term health conditions who want to stay on track with their medicines.
Knoxville, TennesseeAges 18 years+ - NCT06374667Recruiting
Skull bone injection vs. IV for large stroke
This trial tests a new way to give medicine for a large stroke on one side of the brain. The medicine is injected into the skull bone instead of through a vein, and researchers want to see if it works better and is safe.
Wuhu, AnhuiAges 18–80 - NCT06374524Recruiting
Nerve block for spontaneous intracranial hypotension headache
This trial tests a nerve block injection (behind the ear) to see if it can ease the severe headache pain that happens when upright due to spinal fluid leaks. If you have spontaneous intracranial hypotension and your pain is high when standing, this treatment might help.
Toronto, OntarioAges 18 years+ - NCT06374693Recruiting
Nerve stimulation after brain aneurysm repair
This trial tests whether a gentle nerve stimulation device (tVNS) applied to the ear is safe and practical for patients recovering from a specific type of brain bleed. It aims to see if this non-invasive treatment might help recovery after the aneurysm is repaired.
Sheffield, South YorkshireAges 18 years+ - NCT06374719Recruiting
TNNT1 myopathy natural history study
This study follows people with a rare genetic muscle condition called TNNT1 myopathy over time. Researchers will track how the disease progresses to better understand it and help plan future treatments.
Gordonville, PennsylvaniaAges Any age - NCT06375213Recruiting
Memory and thinking study for all ages
This study looks at how well people think and remember as they age. It includes healthy volunteers, people with mild memory issues, and those with dementia—both early- and late-onset.
Pathum Wan, BangkokAges 35 years+ - NCT06375265Recruiting
Sleep improvement program for older surgery patients
This trial tests a digital sleep improvement program for older adults who are about to have knee or hip replacement surgery. It aims to help you sleep better before and after surgery, which may improve your brain health and recovery.
Boston, MassachusettsAges 65 years+ - NCT06375447Recruiting
Smart model for diagnosing and treating insomnia
This trial is testing a new intelligent approach to diagnose and treat insomnia. If you have trouble sleeping and are between 18 and 75, you may be able to join and help improve insomnia care.
BeijingAges 18–75 - NCT06375759Recruiting
Surgery comparison for spinal cavity from injury or infection
This trial tests two surgical options for people with a spinal cord injury or infection that caused a fluid-filled cavity (syrinx) in the spine. It compares a new type of bypass surgery with a procedure to remove scar tissue, to see which helps improve symptoms better.
Beijing, Beijing MunicipalityAges 18–80
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,432 recruiting neurology studies from the U.S. registry right now, out of 19,532 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.