Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,432 recruiting studies in this area right now.
By phase
- Not applicable9,770
- Phase 2785
- Phase 1574
- Phase 3537
- Phase 4342
- Phase 1/Phase 2303
- Phase 2/Phase 3121
Top conditions
- Stroke846
- Parkinson Disease424
- Multiple Sclerosis343
- Alzheimer Disease340
- Dementia226
- Ischemic Stroke200
- Epilepsy196
- Obstructive Sleep Apnea155
- Insomnia153
- Spinal Cord Injuries153
- Sarcopenia149
- Traumatic Brain Injury149
- Acute Ischemic Stroke141
- Cerebral Palsy131
- Mild Cognitive Impairment129
- Pain Management114
- Migraine112
- Amyotrophic Lateral Sclerosis107
Leading sponsors
- Beijing Tiantan Hospital134
- Riphah International University126
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing94
- VA Office of Research and Development93
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California674
- Massachusetts300
- New York291
- Florida274
- Texas267
- Maryland245
- Arizona214
- Alabama209
- Illinois190
- Pennsylvania177
Recruiting studies12,430 total
- NCT06444776Recruiting
Taste and saliva changes during radiotherapy for head & neck cancer
This study looks at how radiation therapy for head and neck cancer changes your sense of taste and saliva. It aims to better understand and manage these side effects.
Aarau, Canton of AargauAges 18 years+ - NCT06444841Recruiting
Memory aids for mild memory loss
This study tests whether using a paper-based or smartphone-based memory support system helps people with mild memory problems remember daily tasks. You and a family member or friend will both participate.
Austin, TexasAges 50 years+ - NCT06444919RecruitingPhase 4
Capsaicin patch for finger osteoarthritis with nerve pain
This study tests if a capsaicin patch (a hot pepper extract) can reduce finger pain in people with osteoarthritis who also have nerve-like pain. It's for those who haven't gotten enough relief from standard painkillers.
Clermont-FerrandAges 18 years+ - NCT06446245RecruitingPhase 2
Doxycycline for brain tuberculosis
This trial tests whether adding the antibiotic doxycycline to standard treatment can improve recovery in patients with tuberculosis of the brain (TB meningitis). It may help reduce brain swelling and damage.
Medan, MedanAges 21 years+ - NCT06446505Recruiting
Decision aid for deep brain stimulation in Parkinson's
This study tests a decision aid to help people with Parkinson's disease who are being considered for deep brain stimulation (DBS) surgery. The goal is to see if the tool helps patients make more informed choices about their treatment.
Aurora, ColoradoAges 18 years+ - NCT06446778Recruiting
Pipeline device for brain aneurysms
This trial tests a treatment called Pipeline Embolization (a thin tube placed in the artery) to fix brain aneurysms that haven't ruptured. It might help stop the aneurysm from growing or bursting.
Guangzhou, GuangdongAges 22–75 - NCT06446830Recruiting
Vitamin B complex for pain relief after cesarean in ICU
This trial tests whether adding vitamin B complex to standard pain medicine can improve pain control after a cesarean section in critically ill women. It aims to find a safer, effective way to manage pain without relying too much on strong opioids.
Cairo, EgyptAges Any age - NCT06446960RecruitingPhase 3
Nerve blocks for stroke-related central pain
This study tests whether numbing the nerves in your painful arm or leg (with a nerve block) can help reduce central pain after a stroke. It aims to find out how the nerves outside your brain and spinal cord may be involved.
Boulogne-BillancourtAges 18 years+ - NCT06447025RecruitingPhase 2
Study of CTI-1601 for people with Friedreich's ataxia
This trial tests an injectable medicine called CTI-1601 for Friedreich's ataxia (FRDA). It is an open-label study, meaning everyone knows they are getting the drug. The study is for people who have taken CTI-1601 before (without serious side effects) or are new to the drug.
Los Angeles, CaliforniaAges 2–60 - NCT06448403Recruiting
Alzheimer's assessment study with brain scans
This study uses brain scans (MRI and EEG) to better understand Alzheimer's disease. It compares people with MCI or Alzheimer's to healthy volunteers to see how the disease affects the brain.
Trondheim, TrønderlagAges 65 years+ - NCT06448546Recruiting
Gut bacteria in Huntington's disease
This study looks at how gut bacteria are different in people with Huntington's disease who have unusual weight changes. You'll provide stool and blood samples to help researchers understand gut health in HD.
Orlando, FloridaAges 18 years+ - NCT06448663Recruiting
Using gut health to improve seizure control in CDKL5 disorder
This study tests whether changing the gut environment can help reduce seizures in children and adults with CDKL5 deficiency disorder, a rare genetic condition that causes hard-to-control seizures. It is designed for people whose seizures aren't controlled by medicine and who do not have other gut issues or special diets.
MilanAges 3–50 - NCT06448975Recruiting
Study of neck surgery for Alzheimer's disease
This trial tests a new surgery on neck lymph vessels to see if it helps people with Alzheimer's. It is for patients aged 60 to 80 with mild to severe Alzheimer's who have had the diagnosis for over a year.
Wuxi, JiangsuAges 60–80 - NCT06449547Recruiting
Risk factors for anxiety and depression in shingles nerve pain
This study looks at what makes people with shingles nerve pain more likely to feel anxious or depressed. By joining, you'll help doctors understand how to better support patients like you.
Wuhan, HubeiAges 18 years+ - NCT06449989Recruiting
Comparing genetics of colorectal cancer and its brain spread
This study compares the genetics of the original colorectal cancer with the cancer that has spread to the brain. It aims to understand how the tumor changes when it metastasizes, which may help guide future treatments.
Moscow, MoscowAges 18 years+ - NCT06450418Recruiting
Digital app for speech and health monitoring
This trial tests a digital app that tracks speech and health changes. It is open to people with certain neurological conditions, their caregivers, and healthy volunteers.
EdinburghAges 16 years+ - NCT06450691Recruiting
ALS Study: Using Skin Cells to Understand the Disease
This study collects a small skin sample (biopsy) from people with ALS, those who carry an ALS gene mutation but have no symptoms, and healthy volunteers. The sample is used to grow cells in the lab to better understand how ALS develops.
ParisAges 18 years+ - NCT06450977Recruiting
MIND diet study for people with multiple sclerosis
This study tests whether the MIND diet (a combination of the Mediterranean and DASH diets) can help people with multiple sclerosis (MS). Participants will receive meals and be monitored remotely, so you can take part from home.
Urbana, IllinoisAges 18–64 - NCT06451172RecruitingEarly Phase 1
New antibiotic eye drops for drug-resistant eye infections
This trial tests a new type of antibiotic eye drop for people with serious eye infections that don't respond to standard antibiotics. It aims to see if these drops can safely treat the infection and help improve vision.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06451133Recruiting
Blood pressure management after traumatic spinal cord injury
This study tests a way to manage blood pressure after a traumatic spinal cord injury. It aims to improve blood flow to the injured area and help recovery.
Houston, TexasAges 18 years+ - NCT06451627Recruiting
Esketamine for better sleep after spinal surgery
This study tests if a low-dose medicine called esketamine (related to ketamine) can help improve sleep after spinal surgery. It is for adults having planned spinal surgery under general anesthesia.
BeijingAges 18–65 - NCT06451692Recruiting
Hospital medication review for patients on many drugs
This study looks at how hospitals can better review and manage medications for patients who take many drugs. Researchers want to see if a structured review process improves medication safety and care.
Aabenraa, Southern DenmarkAges 65 years+ - NCT06451887Recruiting
Predicting brain swelling after stroke treatment
This study looks at how to predict dangerous brain swelling after endovascular treatment for large artery stroke. It uses CT scans to identify patients at risk, which could help doctors monitor and treat them more closely.
Hangzhou, ZhejiangAges 18–80 - NCT06452147Recruiting
Anesthesia and brain health after hip surgery in older adults
This trial is testing different types of anesthesia to see how they affect brain function (memory, thinking) after hip fracture surgery in older adults. It aims to find the safest approach for elderly patients.
Wenzhou, ZhejiangAges 65 years+
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,432 recruiting neurology studies from the U.S. registry right now, out of 19,532 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.