Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,432 recruiting studies in this area right now.
By phase
- Not applicable9,770
- Phase 2785
- Phase 1574
- Phase 3537
- Phase 4342
- Phase 1/Phase 2303
- Phase 2/Phase 3121
Top conditions
- Stroke846
- Parkinson Disease424
- Multiple Sclerosis343
- Alzheimer Disease340
- Dementia226
- Ischemic Stroke200
- Epilepsy196
- Obstructive Sleep Apnea155
- Insomnia153
- Spinal Cord Injuries153
- Sarcopenia149
- Traumatic Brain Injury149
- Acute Ischemic Stroke141
- Cerebral Palsy131
- Mild Cognitive Impairment129
- Pain Management114
- Migraine112
- Amyotrophic Lateral Sclerosis107
Leading sponsors
- Beijing Tiantan Hospital134
- Riphah International University126
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing94
- VA Office of Research and Development93
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California674
- Massachusetts300
- New York291
- Florida274
- Texas267
- Maryland245
- Arizona214
- Alabama209
- Illinois190
- Pennsylvania177
Recruiting studies12,430 total
- NCT06456008Recruiting
Smell and taste loss registry study
This study tracks patients with smell or taste problems at an ear, nose, and throat clinic to learn more about their conditions. Participants will do simple smell/taste tests and fill out questionnaires.
Leuven, Vlaams-BrabantAges Any age - NCT06456437Recruiting
Testing a new technique after clot removal for stroke
This trial tests if a special technique called 'ischemic post-conditioning' can improve recovery after a large vessel stroke. It is for people who have had a major blockage in a brain artery that was successfully opened with a clot retrieval procedure.
Tianjin, Tianjin MunicipalityAges 18 years+ - NCT06456580RecruitingPhase 3
Telitacicept for generalized myasthenia gravis
This trial tests a new medication called Telitacicept for people with generalized myasthenia gravis (gMG). The goal is to see if it can reduce muscle weakness and improve daily function. You may be able to join if you have moderate to severe symptoms and have not had recent thymoma or other serious health issues.
Scottsdale, ArizonaAges 18 years+ - NCT06456684Recruiting
AV133 PET scan study in early Parkinson's disease
This study uses a special PET scan to look at a protein (VMAT2) in the brain that is linked to Parkinson's disease. It helps researchers understand early changes in people with newly diagnosed Parkinson's or those at high risk of developing it.
Beijing, Beijing MunicipalityAges 30 years+ - NCT06456502Recruiting
Non-invasive brain stimulation for long COVID symptoms
This trial tests whether a gentle, non-invasive brain stimulation device can help relieve long COVID symptoms. It involves wearing special gloves and socks that deliver mild electrical pulses to improve how you feel.
Alcorcón, MadridAges 18 years+ - NCT06456814Recruiting
Study on how brain aneurysms form, grow, and rupture
This study looks at medical records from multiple hospitals in China to understand how brain aneurysms develop and when they might rupture. It may help researchers find better ways to predict and treat them.
GuangzhouAges 18–80 - NCT06457217Recruiting
MRSI for minor stroke with large artery blockage
This study uses a special MRI technique (called MRSI) to look at brain chemistry in people who have had a minor stroke due to a blocked large artery. The goal is to see if the scan can help doctors better understand the stroke and guide treatment decisions.
Shanghai, Shanghai MunicipalityAges 18–100 - NCT06457906RecruitingPhase 3
Focused radiation vs whole brain radiation for up to 10 lung cancer brain spots
This trial compares two types of radiation for people with small cell lung cancer that has spread to the brain (10 or fewer spots). One approach uses focused radiation only on the tumors, the other treats the whole brain while trying to protect memory. The goal is to see which works better with fewer side effects.
Beijing, Beijing MunicipalityAges 18–80 - NCT06457945Recruiting
Mind-wandering and daydreaming in narcolepsy and hypersomnia
This study looks at whether people with narcolepsy or idiopathic hypersomnia have different patterns of daydreaming and mind-wandering compared to others with sleepiness but no clear diagnosis. It helps understand how certain brain states during sleep might affect waking thoughts.
LyonAges 18–65 - NCT06458140Recruiting
Cardioneuroablation for severe fainting with heart pauses
This trial tests a procedure called cardioneuroablation to treat severe fainting (reflex syncope) that hasn't been helped by other treatments. The goal is to see if it reduces fainting without causing dangerous heart rhythm problems.
WarsawAges 14 years+ - NCT06458088Recruiting
Sugar-related substances and blood vessel problems in type 1 diabetes
This study looks at how certain sugar-related substances in the blood (called advanced glycation products) are linked to blood vessel problems in people with type 1 diabetes. It follows up with participants from an earlier study at Reims Hospital.
ReimsAges 18 years+ - NCT06458153Recruiting
Imaging speech after cerebellar stroke
This study uses brain scans to understand how the brain controls speech in people who have had a cerebellar stroke. It is looking for both stroke survivors and healthy volunteers to compare.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT06458374Recruiting
Heart Amyloidosis in Carpal Tunnel Surgery Patients
This study looks for people who had carpal tunnel surgery at Ålesund Hospital to check for a rare heart condition called ATTR amyloidosis. It aims to find the disease early and see how common it is.
Ålesund, Møre og RomsdalAges 50 years+ - NCT06458478Recruiting
Gel to help healing after wisdom tooth removal
This trial tests a special gel applied after removing lower wisdom teeth to see if it helps healing. It is for healthy people who need both bottom wisdom teeth taken out.
PerugiaAges 18–35 - NCT06459154Recruiting
Mixed reality for better quality of life in Parkinson's
This trial uses a special mixed-reality headset to help people with Parkinson's disease improve their walking and quality of life. It may be a good fit if you can walk independently and speak Greek.
Nicosia, EngomiAges 60–100 - NCT06459336Recruiting
Comparing two therapies for arm function after stroke
This study tests two different schedules of Constraint-Induced Movement Therapy (CI therapy) to see which better helps stroke survivors regain use of their weaker arm and hand. You may qualify if you can make small wrist and finger movements.
Lahore, Punjab ProvinceAges 45–65 - NCT06459388Recruiting
Balance training methods for stroke recovery
This study compares two types of physical therapy exercises to help stroke survivors improve balance and walking. One method uses arm and leg movements, while the other focuses on the pelvis area.
Lahore, Punjab ProvinceAges 40–65 - NCT06459466Recruiting
Exercise and neck mobilization for nerve-related arm pain
This study tests whether combining gentle exercises with specific neck joint movements can reduce pain and improve movement in people whose neck pain spreads into their arm. It's for people with a condition called cervicobrachial neuralgia (nerve-related neck and arm pain).
Rawalpindi, Punjab ProvinceAges 30–50 - NCT06459830Recruiting
Facial exercises with or without nerve stretches for Bell's palsy
This study tests whether adding gentle nerve exercises (neural mobilization) to standard facial exercises (mime therapy) helps people with Bell's palsy recover more movement and expression. It is for people who have had one-sided facial weakness for 3 to 6 months.
Kasur, Punjab ProvinceAges 20–40 - NCT06460012Recruiting
Phone support for dementia caregivers (living & learning)
This study tests a support program delivered by phone to help caregivers of people with Alzheimer's or dementia manage challenging behaviors and reduce their own stress. You'll receive coaching and resources, answer surveys, and learn practical strategies.
Portland, OregonAges 18 years+ - NCT06460038RecruitingPhase 2
Medication study for constipation in Parkinson's
This study tests whether a medication called tenapanor can help relieve constipation in people with Parkinson's disease. If you have Parkinson's and have been struggling with constipation for at least 6 months, this trial may offer a new option to improve bowel regularity.
Waterloo, IowaAges 50–89 - NCT06460142Recruiting
Biomarker study for giant cell arteritis and polymyalgia rheumatica
This study is looking for biomarkers (biological clues) in people with newly diagnosed or flaring giant cell arteritis (GCA) or polymyalgia rheumatica (PMR). Participating may help researchers find better ways to diagnose and monitor these conditions.
Bonn, North Rhine-WestphaliaAges 18 years+ - NCT06460363Recruiting
Electrical brain stimulation for delirium in ICU patients
This trial tests whether a gentle electrical current applied to the scalp can help treat delirium (sudden confusion) in intensive care patients. It aims to improve recovery in people who have had confusion for more than 24 hours.
KuopioAges 18 years+ - NCT06460675Recruiting
Comparing two muscle-relaxing techniques for piriformis syndrome
This study compares two gentle muscle-relaxing techniques (called muscle energy techniques) to treat piriformis syndrome—a condition where a muscle in the buttock presses on a nerve and causes pain. If you have hip or buttock pain that’s been bothersome for at least 3 months and worsens with sitting, this trial may help find a better way to manage your pain.
Rawalpindi, Punjab ProvinceAges 25–45
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,432 recruiting neurology studies from the U.S. registry right now, out of 19,532 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.