Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,432 recruiting studies in this area right now.
By phase
- Not applicable9,770
- Phase 2785
- Phase 1574
- Phase 3537
- Phase 4342
- Phase 1/Phase 2303
- Phase 2/Phase 3121
Top conditions
- Stroke846
- Parkinson Disease424
- Multiple Sclerosis343
- Alzheimer Disease340
- Dementia226
- Ischemic Stroke200
- Epilepsy196
- Obstructive Sleep Apnea155
- Insomnia153
- Spinal Cord Injuries153
- Sarcopenia149
- Traumatic Brain Injury149
- Acute Ischemic Stroke141
- Cerebral Palsy131
- Mild Cognitive Impairment129
- Pain Management114
- Migraine112
- Amyotrophic Lateral Sclerosis107
Leading sponsors
- Beijing Tiantan Hospital134
- Riphah International University126
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing94
- VA Office of Research and Development93
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California674
- Massachusetts300
- New York291
- Florida274
- Texas267
- Maryland245
- Arizona214
- Alabama209
- Illinois190
- Pennsylvania177
Recruiting studies12,430 total
- NCT06460636Recruiting
Water therapy and relaxation for fibromyalgia pain
This trial tests if combining relaxation exercises with water therapy can help reduce fibromyalgia pain and symptoms. It is for women aged 20 to 39 who are married and have a confirmed fibromyalgia diagnosis.
Rahim Yar Khan, Punjab ProvinceAges 20–39 - NCT06461208RecruitingPhase 3
Fecal transplant for people with cirrhosis
This trial tests whether transplanting healthy gut bacteria (from donor stool) can improve outcomes in people with cirrhosis. If you have mild to moderate cirrhosis, you may be able to join.
BasildonAges 18 years+ - NCT06461312Recruiting
Two nerve blocks for pudendal neuralgia pain relief
This study tests if combining two nerve blocks—one near the pudendal nerve and one at the ganglion impar—can better relieve chronic pelvic pain from pudendal neuralgia. The goal is to find a more effective treatment for people who haven't gotten enough relief from standard treatments.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06461481Recruiting
Follow-up strategies for de-escalating multiple sclerosis treatment
This study tests different ways of monitoring people with relapsing-remitting MS who are reducing or stopping their medication. It aims to find the safest follow-up approach and may help guide future treatment decisions for those with stable disease.
DüsseldorfAges 18 years+ - NCT06461741Recruiting
EMG biofeedback training for balance in MS
This study tests whether a special training method that uses muscle signals (called EMG biofeedback) can help people with MS improve their walking and balance. If you have problems with walking or balance and your MS is stable, you may be able to join.
Hamilton, OntarioAges 18–80 - NCT06461923Recruiting
Home walking therapy for children with cerebral palsy
This study tests a home-based walking therapy program using special shoe insoles that track your child's walking patterns. The goal is to see if it helps improve walking in children with cerebral palsy.
Seoul, Seodaemun-guAges 7–18 - NCT06462092RecruitingPhase 1/Phase 2
Sacituzumab Govitecan and Spinal Chemo for Breast Cancer Spread to Spinal Fluid
This trial tests a combination of a targeted antibody-drug (sacituzumab govitecan) and chemotherapy given into the spinal fluid. It is for people with HER2-negative breast cancer that has spread to the membranes around the brain and spinal cord (leptomeningeal metastases). The goal is to see if this treatment can help control the cancer in the central nervous system.
Huizhou, GuangdongAges 18–75 - NCT06462287RecruitingPhase 2
Testing a substance P blocker for high blood pressure and sleep apnea
This study tests if a drug that blocks substance P can lower a hormone called aldosterone in people with both severe sleep apnea and high blood pressure. If you have these conditions, this trial may help find a new treatment option.
Rouen, FranceAges 18–75 - NCT06462274Recruiting
Blood and brain markers for brain bleed recovery
This study looks for markers in your blood and brain scans that may help doctors better understand and predict outcomes after a spontaneous brain bleed. It is for people with high blood pressure who have had a bleed within the last three days.
Chongqing, Chongqing MunicipalityAges 18–80 - NCT06462430Recruiting
Registry for children with PTEN Hamartoma Tumor Syndrome
This study is creating a registry (a database) of children with PTEN Hamartoma Tumor Syndrome, a condition that can cause growths, large head size, and other health issues. By joining, you help doctors learn more about the condition and how to better care for kids like yours.
IstanbulAges 1 year+ - NCT06462703Recruiting
Tablet app for cognitive problems after brain injury
This study tests a tablet app designed to help with thinking and memory problems caused by a brain injury. You would use the app at home to practice attention, memory, and other mental skills.
ViennaAges 18 years+ - NCT06462768Recruiting
Study of immune cell activity in systemic sclerosis
This study looks at a specific type of immune cell activity (called neutrophil extracellular traps) in the blood of people with systemic sclerosis, other connective tissue diseases, and healthy volunteers. It aims to understand how these cells may be involved in the disease and could lead to better treatments.
ReimsAges 18 years+ - NCT06463028RecruitingPhase 2
Targeted pills plus chemo for advanced endometrial cancer
This trial tests a combination of two targeted pills (sapanisertib and serabelisib) with standard chemo (paclitaxel) for endometrial cancer that has come back or spread. A substudy also looks at combining these drugs with a special diet that lowers insulin levels.
La Jolla, CaliforniaAges 18 years+ - NCT06463561RecruitingPhase 4
CPAP for high cholesterol and sleep apnea
This study tests if CPAP therapy can improve cholesterol and uric acid levels in people with both high cholesterol and moderate to severe sleep apnea. It may help if you have sleep apnea and are looking for additional ways to manage your lipid levels.
Coslada, MadridAges 35–80 - NCT06463743RecruitingPhase 2
Metformin for aging people with MS
This study tests whether metformin, a common diabetes drug, can help people with multiple sclerosis (MS) as they age. It may be used alone or added to your current MS treatment, and the goal is to see if it slows down aging-related changes in MS.
Buffalo, New YorkAges 55–75 - NCT06463899Recruiting
Numbing medicine tubes during bypass surgery
This study tests whether numbing medicine given through two thin tubes placed during heart surgery can help you recover faster and breathe better. It is for adults having on-pump coronary bypass who also have a lung condition or other risk factor.
ReimsAges 75 years+ - NCT06464029Recruiting
Balance and walking study in Parkinson's disease
This study looks at balance problems in people with Parkinson's disease. It uses simple tests to understand what causes trouble with standing and walking, which may help find better treatments.
Minneapolis, MinnesotaAges 45–80 - NCT06464419Recruiting
Effect of surgery position on eye nerve sheath size
This study is for people having kidney stone surgery. It looks at how the position you are in during surgery affects the nerve sheath around your eye, which may help doctors monitor pressure in the brain.
AnkaraAges 18–65 - NCT06464757Recruiting
Laryngomalacia and breathing in children: before and after treatment study
This trial is for children with laryngomalacia (a floppy voice box) who have noisy breathing and trouble breathing. It will check how they are doing before and after treatment, and follow up for one year to see how their quality of life improves.
OsloAges 1 week–12 months - NCT06464744Recruiting
Can brain stimulation help after spinal cord injury?
This trial tests whether repetitive transcranial magnetic stimulation (rTMS), a non-invasive treatment that uses magnetic pulses to stimulate the brain, can improve movement and function in people with chronic spinal cord injury. It may help if you have some movement left below your injury level.
OsloAges 18–80 - NCT06465719Recruiting
Robot-assisted surgery for moderate brain bleeding
This trial tests if a minimally invasive surgery guided by a robotic AI system can help people with moderate bleeding deep inside the brain (basal ganglia). If you qualify, the surgery would happen within 72 hours of your stroke.
Hangzhou, ZhejiangAges 18 years+ - NCT06465758Recruiting
Stroke recovery study
This study is for people who have had a stroke and are in the early recovery phase. It looks at how well patients recover, with a focus on arm and hand movement, to help guide future care.
MilanAges 18 years+ - NCT06465823RecruitingPhase 2
Bumetanide for thinking skills in Down syndrome
This trial tests whether a medication called bumetanide can improve thinking and learning skills in teenagers with Down syndrome. It is a 10-week study that compares bumetanide to a placebo (a pill with no medicine).
RomeAges 10–17 - NCT06466031Recruiting
PET/MRI for guiding glioblastoma surgery
This trial tests whether a special PET scan combined with MRI can help guide surgery for glioblastoma. It is for people with a newly diagnosed, single tumor who are candidates for surgery.
Lodz, Łódź VoivodeshipAges 18–70
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,432 recruiting neurology studies from the U.S. registry right now, out of 19,532 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.