Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,407 recruiting studies in this area right now.
By phase
- Not applicable9,742
- Phase 2782
- Phase 1577
- Phase 3534
- Phase 4342
- Phase 1/Phase 2307
- Phase 2/Phase 3123
Top conditions
- Stroke843
- Parkinson Disease429
- Alzheimer Disease342
- Multiple Sclerosis342
- Dementia226
- Ischemic Stroke200
- Epilepsy197
- Obstructive Sleep Apnea156
- Spinal Cord Injuries153
- Insomnia152
- Sarcopenia150
- Traumatic Brain Injury150
- Acute Ischemic Stroke138
- Cerebral Palsy131
- Mild Cognitive Impairment129
- Migraine114
- Pain Management113
- Amyotrophic Lateral Sclerosis108
Leading sponsors
- Beijing Tiantan Hospital133
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic98
- Xuanwu Hospital, Beijing93
- VA Office of Research and Development92
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California680
- Massachusetts299
- New York292
- Florida274
- Texas267
- Maryland246
- Arizona213
- Alabama209
- Illinois189
- Pennsylvania177
Recruiting studies12,405 total
- NCT05374824Recruiting
Palliative surgery versus more seizure medicines for Lennox-Gastaut
This trial compares two treatment approaches for children with Lennox-Gastaut syndrome: palliative (comfort-focused) surgery versus adding more anti-seizure medicines. It aims to see which option works better for seizure control and day-to-day well-being.
Chicago, IllinoisAges Up to 26 years - NCT07227987Recruiting
Cognitive rehab for anger in Veterans with TBI and PTSD
This study tests a cognitive rehabilitation program to help Veterans with TBI and PTSD manage anger. You and a trusted support person will participate together to learn skills to reduce anger and improve thinking.
Durham, North CarolinaAges 18 years+ - NCT07174310RecruitingPhase 3
Prasinezumab for early Parkinson's disease
This study tests a new medication called prasinezumab, given through a vein (IV), to see if it can slow the progression of early-stage Parkinson's disease. It is for people who are on only one Parkinson's medication and have not yet developed motor complications.
Birmingham, AlabamaAges 50–85 - NCT07241390RecruitingPhase 3
Study of orforglipron for heart and kidney health.
This trial tests if orforglipron can reduce the risk of heart attack, stroke, or kidney failure in people with heart disease or chronic kidney disease.
Bahía BlancaAges 50 years+ - NCT07750561Enrolling by invitation
Turkish questionnaire for facial synkinesis
This study tests a Turkish version of a questionnaire that measures abnormal facial movements (synkinesis) that can happen after facial palsy. It aims to see if the questionnaire works well for Turkish-speaking patients.
Istanbul, CevizlibağAges Up to 18 years - NCT07343297Recruiting
Ask questions about clinical trials
This study helps people learn about clinical trials and find out if they might be a good fit. It is for patients who are already getting treatment at a Karmanos or McLaren center and can read English well enough to complete surveys.
Bay City, MichiganAges 18 years+ - NCT04994015RecruitingTeam says not enrolling
Genetic registry for people with Parkinson’s
This study builds a genetics “registry” of people diagnosed with Parkinson’s disease who agree to genetic testing. Your information may help researchers understand why Parkinson’s happens and improve future treatments.
Birmingham, AlabamaAges 18 years+ - NCT05564936RecruitingTeam says not enrolling
Digital tests for generalized myasthenia gravis using a smartphone
This study tests a smartphone-based digital tool that helps check symptoms in people with generalized myasthenia gravis (MG). It may help patients and clinicians track how the disease is doing over time using simpler, repeated assessments.
Aurora, ColoradoAges 18 years+ - NCT07016971RecruitingPhase 1
CBG/CBD oil for nerve pain from chemotherapy
This trial tests whether a blend of CBG and CBD oils can help relieve nerve pain, tingling, or weakness caused by platinum-based chemotherapy in people with certain gastrointestinal cancers. If you have had colorectal, biliary, pancreatic, esophageal, gastric, or small intestinal cancer and completed chemo in the last 2 years, you may be able to join.
Hershey, PennsylvaniaAges 21 years+ - NCT07075068Recruiting
How smoking affects leg movement and coordination
This study tests how cigarette addiction changes the speed and coordination of your legs. If you are a smoker or a non-smoker, researchers will compare your movement to see if smoking makes a difference.
Istanbul, ÜsküdarAges 18–25 - NCT07049042Recruiting
Hormone study in genetic brain development conditions
This study looks at whether certain genetic brain development conditions affect hormone production in the body. It may help find out if people with these conditions have low sex hormones.
Sheffield, SelectAges birth–99 years - NCT07062367Recruiting
Anesthesia options for laparoscopic hysterectomy and brain health
This study compares three ways to give anesthesia during laparoscopic hysterectomy: one type of gas (sevoflurane) with or without a lidocaine IV drip, versus a different IV anesthesia (propofol). The goal is to see which approach best protects pressure inside your head and oxygen levels in your brain during surgery.
Tanta, El-GharbiaAges 18–65 - NCT07066605Recruiting
Dexmedetomidine for agitation during breathing tube removal
This trial tests whether a sedative called dexmedetomidine can reduce agitation in ICU patients when they are being weaned off a breathing tube. If you experience restlessness or agitation during the weaning process, this medication might help you stay calm.
SohagAges 19 years+ - NCT07072026Recruiting
Opening blocked arteries in the brain long after stroke
This trial looks back at patients who had a procedure to reopen a major artery in the brain that had been blocked for a long time. It will help doctors learn if this treatment is safe and effective for people with chronic blockages in certain key arteries.
EssenAges 18 years+ - NCT07000175Recruiting
Heart rate measurement on arm vs. chest during nerve stimulation
This study compares two ways of measuring heart rate variability (a sign of how well your nervous system is working) during a gentle nerve stimulation therapy. It looks for healthy volunteers to see if a simple arm measurement works as well as a chest measurement.
Trabzon, OrtahisarAges 18–45 - NCT07008612Recruiting
Study of MYT1L syndrome in children and adults
This study looks at MYT1L syndrome, a rare genetic condition that affects brain development. It aims to understand the disorder better by studying people with the syndrome and a comparison group.
RouenAges 6 years+ - NCT06962579Recruiting
Exercise to prevent chemotherapy nerve damage
This study tests whether a personalized exercise program at home can help prevent nerve damage (peripheral neuropathy) caused by certain chemotherapy drugs. It is for people with breast, gynecological, or colon cancer starting a new chemotherapy treatment.
EdegemAges 18 years+ - NCT06983132Recruiting
Natural history of familial cavernous malformations: CCM study
This study follows people with a hereditary form of cavernous malformations (clusters of abnormal blood vessels in the brain). It aims to understand how the condition changes over time, without testing any new treatments.
BariAges Any age - NCT06922071Recruiting
Memory support program for older adults in care
This study offers a memory- and thinking-support program for older adults who are living in a residential facility or attending a daycare center. The goal is to help keep your mind sharp and maintain your well-being as you age.
Coimbra, PortugalAges 65 years+ - NCT06936514Enrolling by invitation
Lymphatic surgery for Alzheimer's: a clinical study
This trial tests a surgery that targets the lymphatic system in the neck to help people with moderate-to-severe Alzheimer's disease. The goal is to see if it can improve cognitive function.
TianjinAges 50–80 - NCT06932679Recruiting
How people with Parkinson’s cross obstacles
This study looks at how people with and without Parkinson’s disease see and step over obstacles while walking. It aims to understand differences in perception and movement to help improve safety and mobility for people with Parkinson’s.
HaifaAges 20–80 - NCT06981156Recruiting
Study of pediatric brain and spine tumor exams
This study tests a shorter way to check the brain and nervous system in children with brain or spine tumors. It aims to see if the new exam is as good as the standard one.
Madison, WisconsinAges 1–17 - NCT06972953Recruiting
Steerable guidewire for brain aneurysm treatment
This trial tests a new steerable guidewire that helps doctors navigate to brain aneurysms without surgery. It is for people with a brain aneurysm that has not burst and can be treated through a blood vessel in the leg.
LimogesAges 18 years+ - NCT06922487Recruiting
Tiredness study during awake brain tumor surgery
This trial looks at tiredness during awake brain surgery for tumor removal. It might help understand how awake procedures affect patients.
LundAges 18 years+
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,407 recruiting neurology studies from the U.S. registry right now, out of 19,276 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.