Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,407 recruiting studies in this area right now.
By phase
- Not applicable9,742
- Phase 2782
- Phase 1577
- Phase 3534
- Phase 4342
- Phase 1/Phase 2307
- Phase 2/Phase 3123
Top conditions
- Stroke843
- Parkinson Disease429
- Alzheimer Disease342
- Multiple Sclerosis342
- Dementia226
- Ischemic Stroke200
- Epilepsy197
- Obstructive Sleep Apnea156
- Spinal Cord Injuries153
- Insomnia152
- Sarcopenia150
- Traumatic Brain Injury150
- Acute Ischemic Stroke138
- Cerebral Palsy131
- Mild Cognitive Impairment129
- Migraine114
- Pain Management113
- Amyotrophic Lateral Sclerosis108
Leading sponsors
- Beijing Tiantan Hospital133
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic98
- Xuanwu Hospital, Beijing93
- VA Office of Research and Development92
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California680
- Massachusetts299
- New York292
- Florida274
- Texas267
- Maryland246
- Arizona213
- Alabama209
- Illinois189
- Pennsylvania177
Recruiting studies12,405 total
- NCT06924359Recruiting
Eye scans and blood tests for early Alzheimer's detection
This study uses special eye scans and blood tests to find early signs of Alzheimer's disease. It aims to detect the disease before memory loss becomes severe, so treatment can start sooner.
BeijingAges 50 years+ - NCT06940232Recruiting
Blood test study for traumatic brain injury in kids
This study is testing whether a blood test can detect traumatic brain injury (TBI) in children. If successful, it could offer a quicker, less invasive way to diagnose concussions and other head injuries, reducing the need for CT scans or MRIs.
Omaha, NebraskaAges Up to 17 years - NCT06836141Recruiting
Biomarkers for memory decline after brain hemorrhage
This study looks for biological signs that might predict memory problems after a brain bleed, which could help doctors provide better care.
Chicago, IllinoisAges 18–80 - NCT06864000Recruiting
Genetic study of a brain condition called CAA
This study looks at the genetic causes of cerebral amyloid angiopathy (CAA), a condition where proteins build up in small brain blood vessels. It aims to better understand the disease and may help guide future treatments.
RouenAges 18–99 - NCT06887647Recruiting
Physical therapy with horses for kids with neuromuscular disease
This trial tests whether physical therapy sessions involving horseback riding can improve arm and hand function in children with neuromuscular disease. It may help kids who can follow simple directions and are comfortable around horses.
Missoula, MontanaAges 6–17 - NCT06832267Recruiting
RMTT chemo for newly diagnosed PCNS lymphoma
This trial tests a combination of four chemotherapy drugs (Rituximab, Methotrexate, Temozolomide, and Thiotepa) as the first treatment for people newly diagnosed with primary central nervous system diffuse large B-cell lymphoma. It aims to see if this regimen is safe and effective for patients who have not had any prior systemic therapy.
Hangzhou, ZhejiangAges 18–75 - NCT06859385Enrolling by invitation
Standing up test for Parkinson's patients
This study tests a simple way to measure how well people with Parkinson's can stand up from lying down. It aims to see if the test is reliable and useful for tracking movement over time.
Gaziantep, Gazi̇azntepAges 40–65 - NCT06886802Recruiting
Study of a new neck surgery for spinal stenosis
This study is looking at a new, less invasive neck surgery for people with cervical spinal stenosis (narrowing of the spinal canal in the neck). It tests whether this surgery helps relieve symptoms like pain, numbness, or weakness in the arms or legs.
San Pedro Garza García, Nuevo LeónAges 18–74 - NCT06871839Recruiting
A study of lencanumab for early Alzheimer's disease
This trial tests an investigational drug called lencanumab for people with early Alzheimer's disease. The goal is to see if it can help with memory and thinking by targeting brain changes caused by Alzheimer's.
BeijingAges 50–90 - NCT06839560RecruitingPhase 2
Immunotherapy plus chemotherapy and radiation for advanced breast cancer with brain metastases
This trial tests a combination of a PD-L1 inhibitor with a low-dose chemotherapy regimen and either immediate or delayed radiation therapy for people with HER2-negative breast cancer that has spread to the brain. The goal is to see if this approach helps shrink brain tumors and improve outcomes.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06804421Recruiting
Treating stroke-like symptoms after brain bleed
This trial is for people who had a brain bleed from a burst aneurysm and need intensive care. It tests better ways to diagnose and treat delayed brain injury that can happen days or weeks later.
Bergamo, BGAges 18 years+ - NCT06731842Enrolling by invitation
Brain scans and blood tests for Alzheimer's disease
This study uses a special brain scan (PET imaging) and blood tests to look for early signs of Alzheimer's and other brain diseases. It aims to improve how we detect and understand these conditions.
StockholmAges 30–85 - NCT06794736Recruiting
Study on metabolic profiles in lower-grade gliomas
This study looks at how lower-grade gliomas (a type of slow-growing brain tumor) use energy. It may help doctors better understand the tumor and choose the best treatment for you.
Bari, ApuliaAges 18 years+ - NCT06783114RecruitingPhase 2/Phase 3
Testing a new Botox-like injection for arm stiffness after stroke
This study tests an investigational botulinum toxin injection (YY001) to reduce muscle stiffness in the arm after a stroke. It may help you move your arm more easily and improve daily tasks.
Hefei, AnhuiAges 18–75 - NCT06752434Recruiting
Comparing two brain stimulation methods for dystonic tremor
This trial compares PSA (a type of deep brain stimulation targeting a different brain area) versus traditional STN DBS for treating dystonic tremor. It aims to see which method provides better tremor control with fewer side effects.
Shanghai, Shanghai MunicipalityAges 18–70 - NCT06775925Recruiting
Robot-assisted vs. standard arm therapy for spinal cord injury
This trial compares robot-assisted arm therapy with standard occupational therapy to see which helps people with a recent cervical spinal cord injury regain hand and arm function better. You may be eligible if you are in early rehab and have limited use of your arms or hands.
Nottwil, Canton of LucerneAges 18 years+ - NCT06737250RecruitingPhase 2
Testing a new drug combo for relapsed brain lymphoma
This trial tests a combination of three drugs (poseltinib, rituximab, and lenalidomide) for people with primary central nervous system lymphoma that has come back or not responded to earlier treatment. The goal is to see if this new mix can help control the disease.
BusanAges 19–80 - NCT06773793Enrolling by invitation
Ultrasound test for nerve damage in diabetes
This trial uses a special ultrasound technique to see if it can detect nerve damage in people with diabetes. It may help doctors find diabetic peripheral neuropathy earlier and more accurately.
Nanjing, JiangsuAges 18–75 - NCT06634498Recruiting
Brain stimulation for internet gaming disorder
This study tests whether a non-invasive brain stimulation technique (rTMS) can help people with internet gaming disorder reduce their gaming urges and improve control. You would receive either real or sham rTMS over several sessions.
Zhenjiang, JiangsuAges 18–30 - NCT06660056RecruitingPhase 1
GC001 injection for returning or growing high-grade brain tumors
This trial tests a new drug, GC001, injected directly into the tumor in people with high-grade gliomas (WHO grade 3 or 4) that have come back or are growing. It may be an option if standard treatments have stopped working.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06629077RecruitingPhase 2
Brain blood vessel response to blood flow changes
This study looks at how blood vessels in the brain react when blood flow changes. It may help researchers understand how the brain adapts with age.
Madison, WisconsinAges 55–69 - NCT06647368Recruiting
Measuring brain sugar use with glucagon
This study tests a new way to measure how the brain uses sugar (glucose) to see if the hormone glucagon affects it. It may help researchers understand how certain hormones work in the body.
CopenhagenAges 25–70 - NCT06680336Recruiting
Cognitive Recovery After Stroke-Related Confusion
This study tests whether a special program can help your thinking and memory recover after a stroke that caused confusion (delirium). You may be able to join if you had a recent ischemic stroke, are 60 or older, and do not have dementia or a severe language problem.
TübingenAges 60 years+ - NCT06369532Recruiting
Brain stimulation and therapy to stop worrying
This trial combines a gentle brain stimulation technique called tDCS with cognitive-behavioral therapy (a type of talk therapy) to help people with generalized anxiety disorder or depression stop worrying.
Ghent, East-FlandersAges 18–70
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,407 recruiting neurology studies from the U.S. registry right now, out of 19,276 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.