Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 11,934 recruiting studies in this area right now.
By phase
- Not applicable9,337
- Phase 2764
- Phase 1555
- Phase 3514
- Phase 4340
- Phase 1/Phase 2299
- Phase 2/Phase 3125
Top conditions
- Stroke797
- Parkinson Disease395
- Alzheimer Disease337
- Multiple Sclerosis330
- Dementia224
- Epilepsy192
- Ischemic Stroke190
- Insomnia159
- Traumatic Brain Injury151
- Obstructive Sleep Apnea142
- Spinal Cord Injuries142
- Acute Ischemic Stroke139
- Sarcopenia135
- Mild Cognitive Impairment126
- Cerebral Palsy119
- Pain Management113
- Migraine107
- Fibromyalgia105
Leading sponsors
- Beijing Tiantan Hospital124
- Assistance Publique - Hôpitaux de Paris109
- Riphah International University105
- Mayo Clinic98
- VA Office of Research and Development92
- Xuanwu Hospital, Beijing89
- Hospices Civils de Lyon77
- Johns Hopkins University69
- University of Minnesota63
- Washington University School of Medicine63
Where studies are running
- California655
- Massachusetts304
- New York295
- Florida267
- Texas267
- Maryland248
- Arizona209
- Alabama205
- Illinois183
- Pennsylvania175
Recruiting studies11,934 total
- NCT07827677Recruiting
Brain stimulation for muscle pain relief in people with insomnia
This study looks at whether different types of brain stimulation (called TMS) can help reduce the muscle pain triggered during a test. It is designed for people who also have insomnia, and who are otherwise healthy.
Hong KongAges 18–60 - NCT07826650Recruiting
How acute pain affects sleep in people with insomnia
This study looks at how a short-term (acute) pain affects sleep quality in people who suffer from insomnia compared to healthy sleepers. Participation may help researchers understand the link between pain and sleep problems.
Hong KongAges 18–60 - NCT07829796Recruiting
Brain stimulation and virtual reality for walking in children with cerebral palsy
This study tests a treatment that uses a gentle electrical current on the scalp (called transcranial direct current stimulation) along with virtual reality exercises to help improve walking and self-esteem in children with spastic cerebral palsy.
IslamabadAges 8–16 - NCT07831499RecruitingPhase 4
Comparing two hormone therapy schedules for brain health in menopause
This study compares two ways of taking estrogen during menopause to see which one better supports memory and thinking. You would receive either a steady dose or a pulse dose of estrogen, along with a progestin, and researchers will track your brain health over time.
Aurora, ColoradoAges 38–60 - NCT07831252Recruiting
Blood pressure and oxygen levels during heart surgery
This study looks at how blood pressure changes during the start of open heart surgery and whether it affects oxygen levels in body tissues. It may help doctors better manage blood pressure during surgery to keep patients safe.
Istanbul, SultangaziAges 18–90 - NCT07829770Recruiting
Brain stimulation with virtual reality for balance in cerebral palsy
This study tests a new type of brain stimulation combined with virtual reality exercises to see if it can improve balance and thinking skills in children with spastic diplegic cerebral palsy. The treatment is non-invasive and aims to help with everyday movement and cognitive function.
IslamabadAges 8–16 - NCT07827001Recruiting
Monitoring brain tumors during systemic treatment
This study tests whether it's safe to skip radiation and instead rely on a new systemic treatment (like immunotherapy or targeted therapy) to control brain tumors that have spread from other parts of the body. It might help you manage your disease while avoiding the side effects of radiation.
Orange, CaliforniaAges 18 years+ - NCT07827716RecruitingPhase 2
Testing terfenadine for relapsing multiple sclerosis
This study tests whether terfenadine, an allergy medicine, is safe and helpful for people with relapsing-remitting multiple sclerosis (MS). It may reduce MS activity and improve outcomes.
Wuhan, HubeiAges 18–65 - NCT04842812RecruitingPhase 1
Personalized immune cell therapy for advanced solid tumors
This Phase 1 study tests engineered immune cells (TILs/CAR-TILs) made from your tumor to treat advanced solid cancers that have not responded to standard treatments. It may help your immune system better recognize and attack the cancer, but it is mainly focused on safety and early results.
GuangzhouAges 18–85 - NCT05095857RecruitingPhase 4
Ketamine to improve care in severe acute brain injury
This Phase 4 trial tests whether giving ketamine during anesthesia is safe and helpful for adults with severe sudden brain injuries after surgery. It may improve how patients are sedated and cared for while they are on a breathing machine.
CopenhagenAges 18 years+ - NCT06472674Recruiting
Healthy Aging Study for Older Adults
This study is looking at healthy aging in older adults who live in the community. It involves completing a survey to help researchers understand how people age well.
BeijingAges 60 years+ - NCT06323434Recruiting
Spinal fluid leaks in chronic subdural hematoma
This study looks for spinal fluid leaks in people with chronic subdural hematoma (a slow buildup of blood on the brain). It uses MRI to find a possible cause, which could help improve treatment.
Freiburg im Breisgau, Baden-WurttembergAges 18 years+ - NCT06450977Recruiting
MIND diet study for people with multiple sclerosis
This study tests whether the MIND diet (a combination of the Mediterranean and DASH diets) can help people with multiple sclerosis (MS). Participants will receive meals and be monitored remotely, so you can take part from home.
Urbana, IllinoisAges 18–64 - NCT06476093Recruiting
Radiation plus anlotinib for lung cancer brain spread
This trial tests a combination of focused radiation (stereotactic radiosurgery) and an oral targeted therapy called anlotinib for people with non-small cell lung cancer that has spread to the brain. It may offer a way to control brain metastases without more invasive procedures.
Lianyungang, JiangsuAges 18–80 - NCT05197738Recruiting
Study using a sleep health app to improve sleep
This study tests a “sleep health” app (REFRESH) to see how it may help people track and improve sleep. You may be eligible if you’re an adult in the U.S. who can use the app on your own phone.
La Jolla, CaliforniaAges 18 years+ - NCT07823465Enrolling by invitation
Brain device study for teens with focal epilepsy
This study looks at how well an implanted brain device works for teenagers with focal epilepsy that doesn't improve with medicine. The device sends small electrical pulses to specific brain areas to reduce seizures, and this study will help learn if it's safe and helpful for teens.
Waltham, MassachusettsAges 13–19 - NCT07821658Recruiting
Lecanemab treatment study for Alzheimer's disease
This study looks at people who are taking or have taken lecanemab (a medication for Alzheimer's disease). It aims to gather more information about the treatment's effects in real-world settings.
Nutley, New JerseyAges Any age - NCT07823608RecruitingPhase 3
Monthly study medicine for adults with sleep apnea and overweight who use a breathing machine
This study tests an investigational medicine taken once a month for adults with moderate to severe sleep apnea who are overweight or have obesity and use a CPAP or similar breathing machine. It aims to see if the medicine improves sleep-related breathing.
Cullman, AlabamaAges 18 years+ - NCT07817758Recruiting
Sarcopenia and surgery outcomes in older gastrointestinal cancer patients
This trial looks at whether low muscle mass (sarcopenia) before surgery affects recovery for older adults with gastrointestinal cancer. It may help doctors personalize care and improve outcomes.
Van, VanAges 60 years+ - NCT06478238RecruitingEarly Phase 1
Calcium folinate for hereditary spastic paraplegia type 56
This trial tests a drug called calcium folinate (a form of vitamin B9) to see if it can help people with a rare genetic type of spastic paraplegia (SPG56). It aims to improve leg stiffness and weakness caused by a specific gene change.
Shanghai, Shanghai MunicipalityAges Any age - NCT05546138Recruiting
Study for early diabetic nerve damage in people with diabetes
This trial looks for and studies early nerve problems in the feet or legs that can happen with diabetes, before nerve damage is clearly diagnosed. It may help doctors better predict who is at risk and understand early changes.
AalborgAges 18–60 - NCT07820800Recruiting
Personalized digital health guidance for middle-aged adults
This study tests whether a digital health app can help middle-aged adults based on their personal metabolic risk. It aims to prevent diseases by providing tailored guidance.
SavonlinnaAges 45–55 - NCT07825155RecruitingEarly Phase 1
Injections for carpal tunnel syndrome: comparing three treatments
This study compares three different injections for carpal tunnel syndrome, a condition where a nerve in your wrist gets squeezed, causing pain, numbness, or tingling in your hand. The goal is to see which injection works best to relieve symptoms.
Tanta, Gharbia GovernorateAges 18–70 - NCT07823101Recruiting
Imaging study of swallowing and speech muscles in muscle diseases
This study uses imaging to look at the muscles involved in swallowing and speaking in people with certain muscle diseases, like inclusion body myositis or ALS. The goal is to better understand these conditions, which might help improve care in the future.
Baltimore, MarylandAges 18 years+
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 11,934 recruiting neurology studies from the U.S. registry right now, out of 18,325 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.