Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,497 recruiting studies in this area right now.
By phase
- Not applicable9,839
- Phase 2787
- Phase 1573
- Phase 3531
- Phase 4344
- Phase 1/Phase 2304
- Phase 2/Phase 3119
Top conditions
- Stroke856
- Parkinson Disease424
- Alzheimer Disease341
- Multiple Sclerosis341
- Dementia228
- Ischemic Stroke201
- Epilepsy196
- Insomnia156
- Obstructive Sleep Apnea155
- Traumatic Brain Injury154
- Spinal Cord Injuries151
- Sarcopenia149
- Acute Ischemic Stroke141
- Cerebral Palsy129
- Mild Cognitive Impairment128
- Migraine113
- Pain Management113
- Amyotrophic Lateral Sclerosis107
Leading sponsors
- Beijing Tiantan Hospital135
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic98
- Xuanwu Hospital, Beijing94
- VA Office of Research and Development92
- Hospices Civils de Lyon79
- Johns Hopkins University71
- National Taiwan University Hospital69
- University of Minnesota63
Where studies are running
- California675
- Massachusetts305
- New York294
- Florida277
- Texas270
- Maryland245
- Alabama213
- Arizona211
- Illinois193
- Pennsylvania177
Recruiting studies12,495 total
- NCT00138931Recruiting
Study genetics of inherited heart and muscle conditions
This study looks at genetic causes of inherited heart (cardiovascular) and muscle/nerve (neuromuscular) conditions. You may be asked about your family history and possibly genetic samples to help connect symptoms to specific genetic changes.
Chicago, IllinoisAges Any age - NCT00921986Recruiting
Store heart rhythm samples for arrhythmia research
This study builds a bank of stored heart rhythm-related samples so researchers can study different heart rhythm problems. It may help you or your family contribute to future testing and better care for arrhythmias.
Cleveland, OhioAges 18 years+ - NCT00001252Recruiting
Movement and Motion Study Database
This study builds a database of how people move and walk—both healthy volunteers and those with movement disorders. Researchers use this information to better understand neuromuscular conditions and improve treatment options.
Bethesda, MarylandAges 1 month–99 years - NCT00001248Recruiting
MRI Brain Imaging Study for Multiple Sclerosis
This research study uses MRI (magnetic resonance imaging)—a safe, non-invasive scanner—to take detailed pictures of your brain and understand how multiple sclerosis (MS) affects it over time. You may qualify whether you have MS or are a healthy volunteer for comparison.
Bethesda, MarylandAges 18–120 - NCT00237315Recruiting
Long-term study of urea cycle disorders in affected families
This study follows people with urea cycle disorders (and some people who are very likely to have one) over time. It aims to better understand how these rare enzyme problems affect health, using medical tests and family information.
Los Angeles, CaliforniaAges Any age - NCT00178724Recruiting
Spinal cord injury registry for people after a first trauma
This trial is a registry that collects information about people 18 and older who have a first spinal cord injury caused by trauma. By sharing details, you help researchers better understand outcomes and care needs after these injuries.
Miami, FloridaAges 18 years+ - NCT00768820RecruitingPhase 4
Study brain and mental health in people with 22q11 deletion
This trial looks at how thinking and mental health (psychiatric symptoms) show up in people who have a specific chromosome deletion. It may help researchers understand patterns in this condition and improve future care.
Petah TikvaAges Any age - NCT00001975Recruiting
Skin Tumors and Tuberous Sclerosis Study
This study looks at skin growths that develop in people with tuberous sclerosis (a genetic condition affecting multiple organs). Researchers want to understand these skin changes better and may test new treatments to help manage them.
Bethesda, MarylandAges 18–90 - NCT01665326Recruiting
Pompe disease screening and follow-up study
This study follows people with Pompe disease over time and checks their “CRIM status,” which is a lab result about a key protein. It may help researchers better understand the disease and how it progresses for different patient groups.
Durham, North CarolinaAges Any age - NCT00017914Recruiting
Understanding muscle inflammation: adult and juvenile myositis study
This research study helps doctors better understand myositis—a group of rare diseases that cause muscle inflammation and weakness. Researchers collect blood samples, medical history, and sometimes muscle biopsies to learn more about what causes these conditions and how to treat them better.
Atlanta, GeorgiaAges 2–100 - NCT00001352Recruiting
Understanding Why Some People Get Fungal Infections
This study looks at genetic reasons why some people are susceptible to a serious fungal infection called cryptococcosis. Researchers will collect blood samples and perform genetic testing to understand the immune system differences that make certain individuals more vulnerable to this infection.
Bethesda, MarylandAges 18–99 - NCT01799915Recruiting
Study of causes and progression of synuclein-related nerve conditions
This study follows people over time to better understand “synucleinopathies,” which are conditions that affect the nervous system as it develops and progresses. You may be asked to return for visits and report symptoms, especially those that happen when you stand up.
Boston, MassachusettsAges 18 years+ - NCT01662453Recruiting
Study risk factors for sudden unexplained death in epilepsy
This study looks at what factors may be linked to sudden, unexplained death in people with epilepsy. Your family’s willingness to participate matters, because the researchers compare cases of sudden unexplained death to people with epilepsy who have not had it.
New York, New YorkAges Any age - NCT02060695Recruiting
Study links Parkinson symptom ups and downs over time
This study looks at how changes in movement symptoms and non-movement symptoms happen together in people with early Parkinson disease. It may help doctors better understand what triggers symptom “ups and downs” and how to time treatment or monitoring.
SeoulAges Any age - NCT01364168Recruiting
Study of new stroke patients and what happens next
This study follows people after a first acute ischemic stroke (a blockage-related stroke) to learn what to expect in the days and months after. Your participation could help doctors better understand recovery and outcomes and improve future care.
BerlinAges 18 years+ - NCT00455104Recruiting
Fabry disease registry for Canadians and eligible adults
This study is a national registry that collects health and medical information from people with Fabry disease. It helps researchers better understand the condition and plan future care and studies.
Calgary, AlbertaAges 5–85 - NCT00001532Recruiting
How Genes Affect Lung Disease Development
This research study examines how genetic factors contribute to various lung diseases, including alpha-1 antitrypsin deficiency, cystic fibrosis, and chronic obstructive pulmonary disease. Researchers want to understand why some people develop lung disease and how genetics plays a role, which may help improve treatment in the future.
Bethesda, MarylandAges 2–90 - NCT00041600Recruiting
Brain Development and Genetic Study for Family Members
This research study investigates how genetic factors affect brain development and function in families where members have brain malformations, intellectual disability, or autism. Researchers hope to identify genetic causes that could lead to better understanding and future treatments.
Boston, MassachusettsAges Any age - NCT00901602Recruiting
Study of invasive pneumococcal infections in Lebanon
This study collects laboratory samples from patients with invasive pneumococcal infections to learn about the germ and where it spreads. It may help doctors and public health teams track infection patterns and improve prevention and treatment planning.
BeirutAges 1 day+ - NCT02069756Recruiting
Duchenne and Becker muscular dystrophy registry
This registry collects information about people with Duchenne or Becker muscular dystrophy, including women who carry the gene (with or without symptoms). It may help researchers better understand the condition and plan future studies.
Washington D.C., District of ColumbiaAges Any age - NCT01730131Recruiting
Study of PML in patients, at-risk people, and healthy volunteers
This study follows people with suspected or confirmed progressive multifocal leukoencephalopathy (PML), people at higher risk, and healthy volunteers. It uses visits, brain imaging (MRI), and stored biological samples to better understand how PML progresses and who is at risk.
Bethesda, MarylandAges 2–120 - NCT00461188Recruiting
Study of inherited pituitary tumor causes
This study looks at the genetics behind pituitary tumors, especially pituitary growth-hormone–related tumors like acromegaly. It may help doctors better understand who these tumors affect and why, which can guide future diagnosis or care.
LeicesterAges 6 years+ - NCT00136500Recruiting
Research study for people with ALS and family risk
This study looks at people affected by ALS (a nerve disease) and, in some cases, family members who may be at genetic risk. It may help researchers better understand ALS and related conditions and improve how they’re studied.
Miami, FloridaAges 18 years+ - NCT00001778Recruiting
Understanding HTLV Infection and HAM/TSP Disease
This research study evaluates people with HTLV infection, a virus that can cause a nerve disorder called HAM/TSP. Researchers want to better understand who gets this condition and why, which may help develop future treatments.
Bethesda, MarylandAges 18–120
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,497 recruiting neurology studies from the U.S. registry right now, out of 19,911 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.