Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,497 recruiting studies in this area right now.
By phase
- Not applicable9,839
- Phase 2787
- Phase 1573
- Phase 3531
- Phase 4344
- Phase 1/Phase 2304
- Phase 2/Phase 3119
Top conditions
- Stroke856
- Parkinson Disease424
- Alzheimer Disease341
- Multiple Sclerosis341
- Dementia228
- Ischemic Stroke201
- Epilepsy196
- Insomnia156
- Obstructive Sleep Apnea155
- Traumatic Brain Injury154
- Spinal Cord Injuries151
- Sarcopenia149
- Acute Ischemic Stroke141
- Cerebral Palsy129
- Mild Cognitive Impairment128
- Migraine113
- Pain Management113
- Amyotrophic Lateral Sclerosis107
Leading sponsors
- Beijing Tiantan Hospital135
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic98
- Xuanwu Hospital, Beijing94
- VA Office of Research and Development92
- Hospices Civils de Lyon79
- Johns Hopkins University71
- National Taiwan University Hospital69
- University of Minnesota63
Where studies are running
- California675
- Massachusetts305
- New York294
- Florida277
- Texas270
- Maryland245
- Alabama213
- Arizona211
- Illinois193
- Pennsylvania177
Recruiting studies12,495 total
- NCT07397377Recruiting
Brain stimulation for slow movement in Parkinson's
This study tests whether a gentle form of brain stimulation (called prTMS) can help improve slow movement in people with Parkinson's. You would come to the Danish Research Centre for Magnetic Resonance for several sessions. The goal is to see if this non-invasive treatment can make daily tasks a bit easier.
HvidovreAges 18–80 - NCT07397559Recruiting
Spinal cord stimulation for spinal cord injury recovery
This trial tests a spinal cord stimulation device to help people with chronic spinal cord injury regain leg movement. It aims to improve muscle control and function.
St Louis, MissouriAges 16–65 - NCT00018889Recruiting
Understanding Movement Disorders Through Genetics and Traits
This research study helps scientists understand how genes and family traits connect to movement disorders like Parkinson's disease or tremor. You may be asked to answer questions about your symptoms, provide family history, and possibly have an MRI scan to help researchers learn more about these conditions.
Bethesda, MarylandAges 2–100 - NCT00682695Recruiting
Study genetic and environmental risks for brain bleeding stroke
This study looks at how genes and life factors may contribute to a type of stroke caused by bleeding in the brain. You may be eligible if you’ve had a spontaneous (not caused by injury or infection) brain bleed and can complete consent, interviews, blood pressure checks, and a DNA sample.
Chicago, IllinoisAges 18 years+ - NCT00390104Recruiting
Study uses blood and skin samples to learn muscular disease causes
This study looks at samples from people with muscular dystrophy and from close relatives, to better understand neuromuscular diseases. You may be asked to provide a skin biopsy for research to help with genetic and molecular analysis.
Boston, MassachusettsAges 1 week–100 years - NCT01694940Recruiting
Mitochondrial disease registry and sample collection study
This trial builds a large database and collection of lab results, and possibly tissue samples, from people with suspected or diagnosed mitochondrial conditions. It helps researchers learn more about these disorders and mitochondrial DNA changes, which may improve future diagnosis and treatments.
San Diego, CaliforniaAges Any age - NCT02098252Recruiting
Study for treating brain blood vessel malformations (AVMs)
This study is looking at treatment options for people who have an abnormal cluster of blood vessels in the brain (an AVM). It may help participants by offering a structured treatment approach, depending on the AVM type and recent symptoms.
Jacksonville, FloridaAges 5 years+ - NCT01703429Recruiting
Alternative care program for people with multiple sclerosis
This study looks at how a complementary or alternative care approach affects people living with multiple sclerosis. It may help to understand whether this type of program improves symptoms or quality of life over time.
Kenmore, WashingtonAges 18–100 - NCT01241305Recruiting
One-Time DNA Study for Different Types of Vasculitis
This trial collects a one-time DNA sample to better understand vasculitis, which are illnesses where blood vessels become inflamed. It may help researchers find why these conditions happen and how they differ across people.
Los Angeles, CaliforniaAges 7 years+ - NCT00060541Recruiting
Evaluation and treatment of brain and nerve surgery conditions
This is a research program at the National Institutes of Health that evaluates and treats people with surgical brain and nerve conditions—like brain tumors, epilepsy, Parkinson's disease, and chronic pain. You'll receive expert evaluation and care while helping doctors learn more about these disorders.
Bethesda, MarylandAges 4–99 - NCT01558479Recruiting
Parkinson’s genetics study for adults in affected families
This study looks at genetic (inherited) factors in Parkinson’s disease. It may help researchers better understand why Parkinson’s happens and could guide future prevention or treatments.
Atlanta, GeorgiaAges 18 years+ - NCT01353547Recruiting
Study genes and environment in multiple sclerosis risk
This study looks at how genes and life exposures may relate to developing multiple sclerosis (MS) or to MS itself. You may be invited if you have a specific connection to MS or certain past immune-related treatments.
Bethesda, MarylandAges 18 years+ - NCT00991094Recruiting
Study follow-up after proton radiation treatment
This study collects information about both short-term and long-term side effects in people who receive proton radiation. It may help doctors better understand what happens to normal tissues over time and improve follow-up care.
Houston, TexasAges 18 years+ - NCT01193075Recruiting
Study of how Charcot-Marie-Tooth (CMT) develops over time
This study follows people who have Charcot-Marie-Tooth disease (CMT) and compares them with people without nerve disease. The goal is to better understand different CMT types and how symptoms and nerve test results change over time.
Los Angeles, CaliforniaAges Any age - NCT01858285Recruiting
Genetics study for children with epilepsy
This study looks for genetic (inherited DNA) causes of epilepsy in children. It may help your family better understand what could be driving seizures, even if the cause isn’t known yet.
Boston, MassachusettsAges Any age - NCT00231400Recruiting
Pompe disease registry for people with confirmed diagnosis
This trial is a registry, meaning it collects health information from people with confirmed Pompe disease. It may help researchers better understand the disease and improve future treatments.
Birmingham, AlabamaAges Any age - NCT01873924Recruiting
Study of Batten disease symptoms and brain function
This study looks at how Batten disease affects the body and thinking/brain function. It may help researchers better understand the condition and how symptoms change over time.
Rochester, New YorkAges Any age - NCT00537004Recruiting
Study of language in primary progressive aphasia
This study looks at how language changes in people with primary progressive aphasia. It may help researchers better understand the condition and how it affects speech and communication over time.
Chicago, IllinoisAges Any age - NCT00697411Recruiting
Study of Aicardi syndrome in X-linked disorders
This trial looks at people with features that suggest Aicardi syndrome, a rare condition that can affect the brain and eyes and may include seizures. Researchers want to better understand the condition and how it shows up, which may help guide care in the future.
Houston, TexasAges Any age - NCT00317616Recruiting
Study for people at high risk of ALS before symptoms start
This study follows healthy people from families with a known ALS-causing gene mutation to look for early body or brain changes before symptoms begin. It may help researchers find ways to predict ALS risk earlier so future treatments can start sooner.
Miami, FloridaAges 18 years+ - NCT00001205Recruiting
Understanding neurocysticercosis outcomes in treated patients
This study follows patients who have been treated for neurocysticercosis—a brain infection caused by a parasite—to learn how they recover over time and what long-term effects they experience. By joining, you'll help doctors better understand this condition and improve care for future patients.
Bethesda, MarylandAges 3–99 - NCT00001595Recruiting
Study of pituitary tumors and related hormone gland disorders
This research study investigates tumors and disorders of the pituitary gland (a small gland that controls many body hormones) and related areas of the brain. You may qualify if you have a pituitary tumor or disorder, or if you have a family history of these conditions.
Bethesda, MarylandAges 2–70 - NCT01601171Recruiting
Genetic study of reproductive problems and cleft lip or palate
This study looks at genetic (inherited) causes of certain hormone and reproductive conditions, including Kallmann syndrome and cleft lip/palate. You might be asked for medical and family history and possibly a DNA sample, helping researchers find what drives these conditions.
Lausanne, Canton of VaudAges Any age - NCT00001208Recruiting
Botulinum toxin for involuntary movement and muscle disorders
This study tests botulinum toxin (a medication that relaxes muscles) to treat various involuntary movements like tremors, muscle spasms, or uncontrolled facial movements. The goal is to see if this treatment can reduce your symptoms and improve your quality of life.
Bethesda, MarylandAges 2–100
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,497 recruiting neurology studies from the U.S. registry right now, out of 19,911 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.