Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,407 recruiting studies in this area right now.
By phase
- Not applicable9,742
- Phase 2782
- Phase 1577
- Phase 3534
- Phase 4342
- Phase 1/Phase 2307
- Phase 2/Phase 3123
Top conditions
- Stroke843
- Parkinson Disease429
- Alzheimer Disease342
- Multiple Sclerosis342
- Dementia226
- Ischemic Stroke200
- Epilepsy197
- Obstructive Sleep Apnea156
- Spinal Cord Injuries153
- Insomnia152
- Sarcopenia150
- Traumatic Brain Injury150
- Acute Ischemic Stroke138
- Cerebral Palsy131
- Mild Cognitive Impairment129
- Migraine114
- Pain Management113
- Amyotrophic Lateral Sclerosis108
Leading sponsors
- Beijing Tiantan Hospital133
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic98
- Xuanwu Hospital, Beijing93
- VA Office of Research and Development92
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California680
- Massachusetts299
- New York292
- Florida274
- Texas267
- Maryland246
- Arizona213
- Alabama209
- Illinois189
- Pennsylvania177
Recruiting studies12,405 total
- NCT07177820Recruiting
Virtual group acupuncture for chemo-related nerve pain
This study tests if virtual group acupuncture can help reduce nerve pain and numbness caused by chemotherapy (called CIPN). It is for people who finished taxane-based chemo for early-stage breast cancer and still have symptoms.
Charlestown, MassachusettsAges 18–80 - NCT06126224RecruitingPhase 3
Testing KarXT for Alzheimer's-related psychosis
This clinical trial tests an investigational oral medication called KarXT for treating psychosis (hallucinations or delusions) in people with Alzheimer's disease. The study aims to see if the drug can safely reduce these symptoms.
Chandler, ArizonaAges 55–90 - NCT07496034RecruitingPhase 3
Gou-Teng-San for frequent migraines
This study tests a Chinese herbal formula called Gou-Teng-San (GTS) for preventing episodic migraines. It is for adults who have frequent migraines but have not tried many prevention medicines.
Taichung, SouthAges 18–70 - NCT07134049Recruiting
Sensory therapy for kids with brachial plexus injury
This study tests whether sensory integration therapy helps young children with a brachial plexus injury (nerve damage in the arm from birth) improve their development. It may be a good option for children who have not had other therapies recently and do not have other major health issues.
AnkaraAges 7 months–2.9 years - NCT06524609RecruitingPhase 1/Phase 2
Green tea extract for nerve damage from chemo
This trial tests whether EGCG (a natural compound found in green tea) can prevent or treat nerve damage caused by the chemotherapy drug Abraxane. It may help people with cancer who are suffering from moderate to severe nerve pain or numbness.
Jinan, ShandongAges 18 years+ - NCT07098650Recruiting
Study on MRI to detect brain bleeding in superficial siderosis
This study uses a special MRI scan to look for signs of bleeding on the surface of the brain in people with superficial siderosis. It also compares these scans to those of healthy volunteers to improve detection and understanding of the condition.
OxfordAges 18 years+ - NCT07127224Recruiting
Predicting recovery with smell tests in coma
This study tests whether a simple smell test can help predict recovery of consciousness in patients who remain in a coma or minimally conscious state after a severe brain injury. If you or your loved one has been unresponsive for several days after sedation is stopped, this trial may provide useful information about prognosis.
Paris, GHU Psychiatrie Et NeurosciencesAges 18 years+ - NCT07568561Recruiting
How Mother's Nutrients Affect Baby Brain Development
This study looks at whether certain nutrients in a pregnant mother's diet—especially B vitamins and related compounds—affect how well her baby's brain develops after birth. Researchers will track mothers' nutrition during pregnancy and check babies' development at 6 months, 1 year, and 2 years.
New Taipei CityAges birth–45 years - NCT07125157Recruiting
Balance training with biofeedback for chronic stroke patients
This study tests if adding biofeedback (visual or sound cues) to task-specific training helps improve balance and reduce fall risk in people who had a stroke more than 3 months ago. It is for patients in Central Lahore, Pakistan.
Lahore, Punjab ProvinceAges 40 years+ - NCT07574645Recruiting
Registry for spinal dural arteriovenous fistula treatment outcomes
This registry collects data from patients who have been treated for a specific type of spinal blood vessel abnormality (Type 1 spinal dural arteriovenous fistula). Researchers use this information to understand how different treatments work and improve care for future patients.
Philadelphia, PennsylvaniaAges Any age - NCT06061185Recruiting
CT scans for recent hemorrhagic stroke
This study uses advanced CT scans to get a better look at bleeding in the brain (hemorrhagic stroke). It may help doctors understand the stroke and guide care.
Beijing, Beijing MunicipalityAges 18–85 - NCT06685380Recruiting
Cognitive Control During Sleep: Self-Awakening Study
This study looks at how our brains control waking up on purpose during sleep. It may help people who can train themselves to wake up at specific times.
Milan, ItalyAges 18–65 - NCT05931328RecruitingPhase 2
Thiotepa plus pomalidomide for recurrent brain lymphoma
This Phase 2 trial tests a combination medicine (thiotepa plus pomalidomide) for people whose primary central nervous system lymphoma has come back or did not respond to prior chemotherapy. It may help shrink lymphoma in the brain/spinal fluid and improve disease control.
Nanjing, JiangsuAges 18–75 - NCT05909618RecruitingPhase 2
Crizanlizumab with nivolumab for brain-spread melanoma or glioblastoma
This Phase 2 study tests crizanlizumab alone or with nivolumab to treat people with certain brain tumors that have spread to the brain (melanoma) or glioblastoma. The goal is to see whether this approach can control the disease and improve outcomes.
Ramat Gan, IsraelAges 18 years+ - NCT07075523Recruiting
Brain scans and markers after CAR T-cell therapy
This study uses brain scans and blood markers to understand how CAR T-cell therapy affects the brain. It may help researchers predict or manage potential side effects.
La Jolla, CaliforniaAges 18 years+ - NCT07650526Recruiting
Brain Stimulation for Nerve Pain Relief
This study tests two types of magnetic brain stimulation (aiTBS and rTMS) to treat long-lasting nerve pain. Researchers want to see which approach works better and develop a way to predict who will benefit most.
Boulogne-Billancourt, Île-de-France RegionAges 18–80 - NCT04290130Enrolling by invitation
Study brain signals during audiovisual speech in neurosurgery patients
This study measures brain activity to understand how your brain combines what you see and hear during speech. It may help scientists build better ways to understand and treat problems with speech processing.
Philadelphia, PennsylvaniaAges 21–65 - NCT06715995Recruiting
Light stimulation's effect on brain waves in healthy older adults
This trial tests if a special light (gamma light) can change brain wave patterns in healthy adults over 55. It aims to understand how light might help keep the brain sharp.
Taoyuan, GuishanAges 55 years+ - NCT07584434RecruitingPhase 1
Safety and Dosage Study of VX-433 in Healthy People
This is a first-in-human study testing a new drug called VX-433 to see how safe it is and how the body handles it. Vertex Pharmaceuticals is running this early-stage trial to understand the right dosage and side effects in healthy volunteers.
Salt Lake City, UtahAges 18–55 - NCT05892419Enrolling by invitation
Brain signal test during memory tasks to predict later learning
This study checks brain activity while you do memory (thinking) tasks, to see whether those signals can predict how well you remember information long-term. It may help researchers understand which brain patterns go with successful memory.
Chicago, IllinoisAges 18–35 - NCT06913725RecruitingPhase 2
Testing FCN-159 for Brain AVM
This trial tests an oral medication called FCN-159 for people with a high-grade brain AVM that has never bled. The goal is to see if it can shrink the AVM or prevent future problems.
Beijing, Beijing MunicipalityAges 18–60 - NCT07034105Recruiting
Walking patterns in healthy people and stroke survivors
This study compares how people walk on different surfaces and with body weight support. It aims to understand walking differences between healthy individuals and stroke survivors, which could help design better rehab programs.
DhakaAges 18–75 - NCT06556199RecruitingPhase 1/Phase 2
Study of selinexor combo for returning brain lymphoma
This trial tests a new combination of drugs (selinexor, temozolomide, and an immunotherapy) for people whose primary central nervous system lymphoma has come back or stopped responding to previous treatment. The goal is to see if this combination can help shrink or control the lymphoma.
Hanzhou, ZhejiangAges 18–75 - NCT06721468Recruiting
Trout eating and brain health in kids and families
This study looks at how eating trout may affect brain health in children and their families. It has three parts for different age groups, and you may be asked to eat trout or answer questions online.
Moscow, IdahoAges 3 years+
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,407 recruiting neurology studies from the U.S. registry right now, out of 19,276 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.