Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,407 recruiting studies in this area right now.
By phase
- Not applicable9,742
- Phase 2782
- Phase 1577
- Phase 3534
- Phase 4342
- Phase 1/Phase 2307
- Phase 2/Phase 3123
Top conditions
- Stroke843
- Parkinson Disease429
- Alzheimer Disease342
- Multiple Sclerosis342
- Dementia226
- Ischemic Stroke200
- Epilepsy197
- Obstructive Sleep Apnea156
- Spinal Cord Injuries153
- Insomnia152
- Sarcopenia150
- Traumatic Brain Injury150
- Acute Ischemic Stroke138
- Cerebral Palsy131
- Mild Cognitive Impairment129
- Migraine114
- Pain Management113
- Amyotrophic Lateral Sclerosis108
Leading sponsors
- Beijing Tiantan Hospital133
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic98
- Xuanwu Hospital, Beijing93
- VA Office of Research and Development92
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California680
- Massachusetts299
- New York292
- Florida274
- Texas267
- Maryland246
- Arizona213
- Alabama209
- Illinois189
- Pennsylvania177
Recruiting studies12,405 total
- NCT07083180Recruiting
Virtual reality hypnosis for carpal tunnel surgery anxiety
This trial tests if using virtual reality and medical hypnosis before surgery can help reduce anxiety for people having their first carpal tunnel surgery.
Saint-Aubin-sur-ScieAges 18 years+ - NCT07085299Recruiting
Gut bacteria and recovery in brain artery narrowing
This study looks at how the bacteria in your gut might affect outcomes in people with narrowed brain arteries. Researchers will track your health over time to see if there are links between your gut bacteria and your recovery.
Nanjing, JiangsuAges 30–80 - NCT07695610Recruiting
Studying unknown movement disorders in children in Vietnam
This trial is for children in Vietnam who have a movement disorder with an unknown cause. Researchers want to learn more by doing genetic testing, which might help find better treatments or answers for families.
Ho Chi Minh City, Ho Chi Minh CityAges Up to 18 years - NCT07191431Recruiting
Study of drug combo for returning brain lymphoma
This trial tests a combination of drugs (Orelabrutinib and Selinexor) with either Methotrexate, Thiotepa, or Temozolomide for people whose brain lymphoma has come back or not responded to prior treatment. The goal is to see if this combination is safe and effective.
Shanghai, Shanghai MunicipalityAges 14–80 - NCT07095790RecruitingPhase 4
Tirofiban plus aspirin and clopidogrel for mild stroke
This trial tests whether a combination of a clot-preventing drug (tirofiban) followed by two antiplatelet drugs (aspirin and clopidogrel) can improve recovery in people who have had a mild stroke. It aims to find a better way to prevent further strokes or worsening symptoms.
Suzhou, AnhuiAges 18–80 - NCT07587463Recruiting
Swiss Ball vs. Movement Training for Stroke Balance Recovery
This study compares two exercise approaches—using a Swiss ball and movement-based training—to help stroke survivors improve their balance and ability to move around safely. You'll do exercises at a medical center to see which method works better for restoring everyday movement skills.
Lahore, Punjab ProvinceAges 45–65 - NCT07096960Recruiting
Testing a caregiver support program for dementia in Brazil
This trial is testing a support program called START for family caregivers of people with dementia in Brazil. It aims to see if the program can be put into practice and if it helps caregivers feel less stressed.
Vitória, Espírito SantoAges 18 years+ - NCT05769348Recruiting
PET brain study to test opioid signaling in migraine
This study uses brain scans (PET) to look at how the body’s “opioid” pain system works in people with migraine. It may help researchers understand migraine biology and test approaches that could improve migraine treatment.
Ann Arbor, MichiganAges 18–65 - NCT06281093Recruiting
Radio waves and preemies' brain development
This trial checks if radiofrequency fields (like from phones or WiFi) affect the nervous system of preterm babies born between 26 and 34 weeks of pregnancy. It helps us understand if we need to protect these babies from such fields.
Amiens, PicardieAges 1 day–1 month - NCT07161258RecruitingPhase 2
Fenebrutinib for children with relapsing MS
This study tests a new oral medication called fenebrutinib for children and teenagers with relapsing multiple sclerosis. It aims to find the right dose and see how safe and effective it is compared to standard treatments.
Rosario, Santa Fe ProvinceAges 10–17 - NCT07323407Recruiting
Brain stimulation for hard-to-treat constipation with bodily distress
This trial tests if a gentle electrical current applied to the scalp can improve severe constipation in people who also experience persistent physical symptoms (like pain or bloating) that cause high worry. It is for those who have not gotten relief from standard laxatives.
Xi'an, ShaanxiAges 18–80 - NCT07115394Recruiting
Brain wave tracking during DBS for movement disorders
This study uses EEG (a non-invasive scalp recording) to measure brain signals while deep brain stimulation (DBS) is active. It aims to better understand how DBS affects brain activity in people with Parkinson's disease, essential tremor, or dystonia.
HamburgAges 35–85 - NCT06209645Recruiting
Personalized brain stimulation for stubborn nerve pain relief
This study tests a non-invasive, personalized brain stimulation technique to reduce nerve pain that has not responded to standard treatments. It may be a good option if you have had nerve pain for over a year and have already tried other pain medications without enough relief.
BronAges 18–80 - NCT07153627Recruiting
Rectal Ozone Therapy for Children with Brain Injury
This trial tests if giving ozone gas through the rectum can help protect the brain and improve recovery in children who have suffered a sudden brain injury. It is for children in the ICU who have lasting problems from the injury.
CairoAges 1 month–18 years - NCT07152925Recruiting
Brain stimulation for impulse control in teens with self-injury
This trial tests whether a gentle electrical current applied to the scalp can improve impulse control in adolescents who harm themselves without wanting to die. The goal is to see if this non-invasive treatment can help reduce self-injury urges.
Hefei, AnhuiAges 12–22 - NCT07150637Enrolling by invitation
Predicting muscle weakness in children on a breathing machine
This study aims to predict muscle weakness that can happen to children on breathing machines in the ICU. It could help doctors start treatments earlier to prevent this weakness.
Shanghai, Shanghai MunicipalityAges 1 month–18 years - NCT07456358Recruiting
Immune attack targets in brain disease
This study looks at the immune system's role in neurological problems caused by cancer immunotherapy or autoimmune diseases. Researchers will collect spinal fluid to find out which immune targets are involved, which may help improve diagnosis and treatment.
Le Kremlin-BicêtreAges 18 years+ - NCT06629090RecruitingPhase 2
Brain blood vessel responses to blood flow changes: younger adults
This study looks at how the brain's blood vessels respond to changes in blood flow in healthy younger adults. It helps researchers understand normal brain aging.
Madison, WisconsinAges 20–40 - NCT07520565RecruitingPhase 3
Emergency stroke treatment with BXOS110 within 3 hours
This trial tests whether BXOS110, an experimental injection, can help people recover better after an acute ischemic stroke (a stroke caused by a blood clot) when given within 3 hours of symptom onset. The study compares BXOS110 to a placebo to see if it reduces disability and improves recovery.
Hengshui, HebeiAges 18–85 - NCT05703685RecruitingPhase 1
Imaging brain inflammation target in depression with PET
This Phase 1 study uses a PET brain scan tracer to see how a specific brain target (PDE4B) is involved in major depressive disorder (MDD). It’s mainly testing whether the imaging approach works and what it shows in people with depression who meet specific safety and medication rules.
Bethesda, MarylandAges 18–70 - NCT06163820RecruitingPhase 1/Phase 2
Bevacizumab and immunotherapy with radiation for melanoma brain metastases
This trial tests a combination of a drug that stops blood vessel growth (bevacizumab), immunotherapy, and focused radiation to treat melanoma that has spread to the brain and is causing symptoms. The goal is to see if this approach shrinks tumors and improves outcomes.
Melbourne, VictoriaAges 18 years+ - NCT06216002Recruiting
Residual paralysis after cancer surgery in frail patients
This trial checks how often muscle relaxant effects linger after gynecologic cancer surgery, especially in frail patients. It uses a nerve stimulator to measure muscle function after surgery.
Bangkok, BangkokAges 18 years+ - NCT07053631Recruiting
New method to measure skull pressure using an eye vein
This study tests a new way to measure pressure inside the skull by using a small vein near your eye. It is for people who are already having a routine test to check fluid pressure around the brain.
Freiburg im BreisgauAges 18–95 - NCT06527287Recruiting
Ankle training for stability in active adults
This trial tests a new ankle training program for people with chronic ankle instability who are physically active. It aims to improve ankle function and reduce the risk of future injuries.
Lexington, KentuckyAges 18–44
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,407 recruiting neurology studies from the U.S. registry right now, out of 19,276 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.