Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,407 recruiting studies in this area right now.
By phase
- Not applicable9,742
- Phase 2782
- Phase 1577
- Phase 3534
- Phase 4342
- Phase 1/Phase 2307
- Phase 2/Phase 3123
Top conditions
- Stroke843
- Parkinson Disease429
- Alzheimer Disease342
- Multiple Sclerosis342
- Dementia226
- Ischemic Stroke200
- Epilepsy197
- Obstructive Sleep Apnea156
- Spinal Cord Injuries153
- Insomnia152
- Sarcopenia150
- Traumatic Brain Injury150
- Acute Ischemic Stroke138
- Cerebral Palsy131
- Mild Cognitive Impairment129
- Migraine114
- Pain Management113
- Amyotrophic Lateral Sclerosis108
Leading sponsors
- Beijing Tiantan Hospital133
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic98
- Xuanwu Hospital, Beijing93
- VA Office of Research and Development92
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California680
- Massachusetts299
- New York292
- Florida274
- Texas267
- Maryland246
- Arizona213
- Alabama209
- Illinois189
- Pennsylvania177
Recruiting studies12,405 total
- NCT07560280Recruiting
Tinnitus from Jugular Vein Narrowing: Diagnosis and Surgery Study
This study evaluates whether neck vein narrowing causes a specific type of tinnitus (ringing in the ears) and tests surgical treatment. If you have persistent tinnitus and imaging shows a narrowed jugular vein, this trial may help determine if surgery could help.
Beijing, Beijing MunicipalityAges 18–75 - NCT07109245RecruitingPhase 4
Do antipsychotics block insulin action in the brain?
This study tests whether a single dose of a common antipsychotic medication affects how the brain responds to insulin, which could help explain weight gain and metabolic side effects. Healthy young adults will receive either the antipsychotic or a placebo, then have their brain activity measured with an MRI.
Toronto, OntarioAges 18–35 - NCT07559097RecruitingPhase 1/Phase 2
Methotrexate-loaded vesicles injected into spine fluid for lung cancer spread to brain membranes
This study tests a new way to deliver a cancer drug directly into the fluid around your brain and spinal cord to treat lung cancer that has spread to the membranes covering the brain. It may help patients whose cancer hasn't responded to standard treatments.
Zhengzhou, HenanAges 18 years+ - NCT06726408Recruiting
Better brain monitoring for babies in the ICU
This study tests a new way to monitor the brains of very young children (under 2 years old) in the ICU. It aims to give doctors better information to help protect your child's brain.
NantesAges Up to 2 years - NCT05881226Recruiting
Study using biomarkers to learn about neurological diseases
This study looks at “biomarkers,” which are measurable signs in the body, to learn more about neurological diseases. If you join and can be followed over time, your information may help researchers understand disease patterns and improve care.
Changchun, JilinAges Any age - NCT07586553Recruiting
Walking Test Study for Older Adults With Memory Concerns
This study tests a special walking pattern called the figure-of-8 walk in older adults who are noticing memory problems but don't have dementia yet. Researchers want to understand how walking ability connects to thinking and memory changes.
Balıkesir, BigadiçAges 65 years+ - NCT07593313Recruiting
Treatment for pain after stroke using spinal stimulation
This trial tests a treatment called spinal cord stimulation for people who develop chronic pain after a stroke. The pain is caused by the stroke itself and doesn't respond well to regular pain medicines. The treatment uses a small device to send mild electrical signals to your spinal cord to reduce pain.
Nanchong, SichuanAges 18 years+ - NCT05617833RecruitingPhase 1
Test EPO and melatonin for brain bleeding in very preterm babies
This Phase 1 trial studies whether giving erythropoietin (EPO) and melatonin is safe in very preterm infants who have bleeding in the brain (intraventricular hemorrhage) or significant nearby brain injury. It aims to see if these medicines can be given safely during the early days after birth.
St. Petersburg, FloridaAges 12 hours–2 months - NCT05845333Recruiting
Study brain changes in women with recent stimulant use
This trial looks at neurocognitive (thinking and brain function) differences in high-risk women who have used stimulant drugs recently. It may help researchers understand how stimulant use affects the brain and which brain changes are linked to thinking and behavior.
Albuquerque, New MexicoAges 18–70 - NCT07154056Recruiting
Spinal cord stimulation for stubborn nerve pain
This trial tests a new type of spinal cord stimulation for people with long-term nerve pain that hasn't improved with other treatments. The goal is to see if this special stimulation pattern can reduce pain better than standard care.
Poitiers, FranceAges 18–80 - NCT06732648RecruitingPhase 2/Phase 3
Testing a new drug for severe brain swelling after a large stroke
This trial tests a new drug called HRS8179 to reduce severe brain swelling after a large stroke. If you have a major stroke on one side of the brain and can start treatment within 10 hours, this study may help prevent dangerous pressure buildup.
Beijing, Beijing MunicipalityAges 18–80 - NCT06385223Recruiting
Personalized brain stimulation for hard-to-treat depression
This study tests a new, personalized form of brain stimulation (called TMS) using MRI scans to target the right areas for people whose depression hasn't improved with medication. It aims to see if this tailored approach works better than standard TMS.
SingaporeAges 21 years+ - NCT05834920Recruiting
Neurofeedback and brain stimulation to improve attention
This trial studies whether training your brain signals (neurofeedback) and sending gentle pulses to the brain (transcranial pulse stimulation) can improve attention. You might be a candidate if you’re an adult with below-threshold sustained attention scores and meet safety and health requirements.
Hong KongAges 20 years+ - NCT07090941Recruiting
Clot removal for severe basilar artery stroke
This trial tests a procedure to remove a blood clot from the main artery at the back of the brain (basilar artery) in people who have a large stroke. The goal is to see if this treatment can improve recovery even when the stroke damage is bigger than usual.
Haikou, HainanAges 18 years+ - NCT07089862Recruiting
Indobufen vs aspirin for unruptured brain aneurysm treatment
This trial compares two anti-clotting drugs—indobufen and aspirin—to see which works better for people getting a stent or flow diverter for an unruptured brain aneurysm. The goal is to find which drug causes fewer bleeding or clotting problems.
Beijing, Beijing MunicipalityAges 18–75 - NCT07085663Recruiting
Exergame brain and body training for adults 50-60 in China
This study tests whether combining exercise video games with memory and thinking tasks can help middle-aged adults who feel their memory is getting worse. It aims to see if this type of training can improve both physical and mental function.
Chengdu, SichuanAges 50–60 - NCT07536568Recruiting
Caffeine to speed recovery after eye surgery in older adults
This study tests whether a small dose of caffeine placed under the tongue helps older adults wake up faster and feel less confused after eye surgery under general anesthesia. Researchers want to see if this simple approach can improve how quickly patients recover and reduce post-surgery agitation.
CairoAges 65 years+ - NCT07569952Recruiting
Nerve Block to Improve Surgical Field in Pituitary Surgery
This trial tests whether blocking a specific nerve in the face (sphenopalatine ganglion) during pituitary tumor surgery improves the surgeon's view and reduces bleeding. Pituitary adenomas are non-cancerous tumors in the brain that are removed through the nose using a camera.
CairoAges 1.8 years–60 years - NCT05807178Recruiting
Light treatment to stabilize sleep-wake rhythm in ICU delirium
This trial tests whether controlled bright light in the ICU can improve confusion and the sleep-wake rhythm in adults who develop delirium. If it works, it may help patients become more clear-minded sooner while they recover in intensive care.
BerlinAges 18 years+ - NCT07571395Recruiting
Nerve monitoring during surgery to track muscle relaxation
This trial tests a nerve-monitoring method during elective surgery to track how well muscle-relaxing medications are working. Doctors will place small sensors on your arms to measure nerve and muscle activity, which may help them give you the right dose of anesthesia.
DebrecenAges 18 years+ - NCT05824728RecruitingPhase 2
Levetiracetam for Parkinson’s psychosis with study partner support
This Phase 2 study tests whether AGB101 (levetiracetam) can reduce hallucinations, delusions, or related symptoms in people with Parkinson’s disease psychosis, while checking safety. You and a study partner will help with dosing and regular check-ins, including MRI scans.
Baltimore, MarylandAges 40–85 - NCT05913297Recruiting
Checking how Chiari malformation affects airways and sleep in children
This study looks at how Chiari malformation (types 1 and 2) may affect a child’s breathing/airways, the base of the skull, and sleep. The results may help doctors better understand which problems to watch for and how to evaluate them.
Rome, ItalyAges 3–18 - NCT07074574Recruiting
Brain-smell study in adults
This study looks at parts of the brain that process smell, specifically a region called the amygdala. It may help researchers understand how smells affect emotions and memory.
Chicago, IllinoisAges 18 years+ - NCT05800223RecruitingPhase 3
Armatinib with or without brain radiation for EGFR lung cancer
This study tests whether armatinib alone or combined with focused brain radiation (SRT) can control brain metastases from EGFR-mutated non-small cell lung cancer. It aims to improve outcomes for people with few, mostly low-symptom brain spots.
Shanghai, Shanghai MunicipalityAges 18–75
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,407 recruiting neurology studies from the U.S. registry right now, out of 19,276 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.