Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,406 recruiting studies in this area right now.
By phase
- Not applicable9,740
- Phase 2783
- Phase 1576
- Phase 3534
- Phase 4342
- Phase 1/Phase 2307
- Phase 2/Phase 3124
Top conditions
- Stroke841
- Parkinson Disease427
- Alzheimer Disease342
- Multiple Sclerosis341
- Dementia227
- Ischemic Stroke201
- Epilepsy197
- Obstructive Sleep Apnea156
- Insomnia154
- Spinal Cord Injuries153
- Traumatic Brain Injury150
- Sarcopenia149
- Acute Ischemic Stroke138
- Cerebral Palsy131
- Mild Cognitive Impairment130
- Migraine113
- Pain Management113
- Amyotrophic Lateral Sclerosis108
Leading sponsors
- Beijing Tiantan Hospital133
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing93
- VA Office of Research and Development92
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California681
- Massachusetts299
- New York292
- Florida275
- Texas265
- Maryland246
- Arizona212
- Alabama210
- Illinois188
- Pennsylvania177
Recruiting studies12,404 total
- NCT06634147Recruiting
Exercise program to prevent decline in hospitalized older adults
This study is testing a gentle exercise program for older adults (75+) while they are in the hospital. The goal is to see if it helps prevent loss of strength, memory, or thinking skills.
Pamplona, NavarreAges 75 years+ - NCT06633406Enrolling by invitation
How anesthesia during pregnancy affects child development
This study looks at how being exposed to general anesthesia before birth might affect a child's thinking skills and brain development. It compares children who were exposed to anesthesia during a mother's surgery (like for appendicitis) with children who were not exposed, and also with children whose mothers had inflammatory bowel disease. The goal is to see if anesthesia plays a role in learning or emotional challenges later in childhood.
Bonheiden, AntwerpenAges 2–27 - NCT07216339Recruiting
Can a game make the walking test more fun for kids?
This study tests if adding game-like features to a standard 6-minute walking test makes it more engaging for children with muscle or nerve disorders. It may help kids stay motivated and perform better during the test.
Lexington, KentuckyAges 6–12 - NCT06627686Recruiting
Predicting successful breathing tube removal in brain injury patients
This study tests if simple breathing tests can predict whether a patient with a traumatic brain injury will successfully breathe on their own after a breathing tube is removed. The goal is to make the removal process safer.
Tanta, MahalaAges 18–65 - NCT06623721Enrolling by invitation
Ear stimulation during movement for stroke and injury recovery
This study tests a gentle ear stimulation device that activates a nerve when you move your arm or leg, to see if it helps your recovery after a stroke or brain/spinal cord injury. If you still have some weakness, this could be a way to boost your rehabilitation.
WeggisAges 18 years+ - NCT06382649RecruitingPhase 2
Rivastigmine for drug-induced confusion
This study tests whether the drug rivastigmine can help people who are very agitated and confused due to certain drug side effects. If it works, it could calm them down and improve their confusion.
St Louis, MissouriAges 10 years+ - NCT06617962Recruiting
Testing two new blood tests for MOGAD diagnosis
This study is testing two new blood tests to see if they can better diagnose MOGAD, an inflammatory condition that affects the brain and spinal cord. If you or your doctor suspects MOGAD, this trial may help confirm the diagnosis.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06802133Recruiting
Study of a new dural repair patch
This trial tests a special patch called DuraMatrix-Onlay Plus that helps repair the protective covering of the brain (the dura mater). It may be an option if you need this type of repair during surgery.
Augusta, GeorgiaAges 18 years+ - NCT06611254Recruiting
Ultrasound to see blood flow in babies getting cooling therapy
This study uses a special ultrasound with a contrast dye to look at blood flow in the brain and kidneys of newborns with birth asphyxia (lack of oxygen) during cooling treatment. It helps doctors understand how cooling affects these organs.
Erlangen, BavariaAges Any age - NCT06611748Recruiting
Hand function restoration after spinal cord injury
This trial tests a device to help people with cervical spinal cord injury improve hand function. It's for those with certain levels of paralysis and some residual arm strength.
Cleveland, OhioAges 18 years+ - NCT05963451Recruiting
Testing treatments for long-term low back pain from facet joints
This study focuses on people with long-lasting low back pain that likely comes from the small “facet” joints in the lower spine. It aims to better understand brain, psychological, and biology changes to help optimize treatment for this type of back pain.
Sherbrooke, QuebecAges 18–75 - NCT07520214Enrolling by invitationEarly Phase 1
Cancer vaccine to prevent glioblastoma recurrence
This early-stage study tests a personalized cancer vaccine designed to prevent glioblastoma (a serious brain tumor) from coming back after surgery and standard treatment. The vaccine aims to train your immune system to recognize and attack any remaining cancer cells.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06595212Recruiting
Twins study on ALS and FTD with genetic and environmental focus
This study looks at twins where at least one has ALS (a nerve disease) or FTD (a brain disorder) to understand how genes and environment affect these conditions. It may help if you and your twin both want to join.
Modena, ItalyAges 18 years+ - NCT07405060Recruiting
How age and muscle fatigue affect balance and control
This study looks at how getting older and muscle tiredness change your ability to keep your balance and control your movements. It may help explain why some people are more likely to fall.
TaoyuanAges 20–85 - NCT06592196Recruiting
Statin liver safety in neurology patients
This study is looking at the safety of statin medications (cholesterol-lowering drugs) on the liver in people hospitalized for neurological conditions like stroke, headache, or dizziness. The goal is to see if these drugs are safe for this group of patients.
Shanghai, Shanghai MunicipalityAges 18–85 - NCT06589557Enrolling by invitation
VR therapy for neck disc disease
This study tests a new VR therapy to help people with neck pain caused by cervical disc disease. It aims to improve movement and reduce pain without surgery.
Rzeszów, Al. Rejtana 16CAges 18–65 - NCT07735078Recruiting
Smart balance and thinking exercise for older adults
This study tests a smart digital tool that combines balance and thinking exercises to help older adults stay steady and prevent falls. If you are 55+ and can walk a short distance, you may be able to join.
Taipei, TaipeiAges 55 years+ - NCT06271785Recruiting
Predicting success of epilepsy surgery in children
This study uses a special, detailed brain-mapping technique (called high-resolution electrical source imaging) to see how well it can predict success after epilepsy surgery in children. It aims to help doctors decide which children might benefit most from surgery.
AngersAges 2–17 - NCT06569212RecruitingPhase 4
Beta-blocker to reduce heart damage after brain bleed
This trial tests whether a common beta-blocker (metoprolol) can protect the heart from injury and reduce inflammation after a bleed in the brain (subarachnoid hemorrhage). It may help patients recover better after this type of stroke.
Portland, MaineAges 18 years+ - NCT06565572Enrolling by invitationEarly Phase 1
Antisense drug for PCARP disease caused by FLVCR1 mutation
This trial tests a new drug called an antisense oligonucleotide (a type of genetic medicine) for people with a specific form of inherited eye disease called PCARP, which is caused by changes in the FLVCR1 gene. The goal is to see if the drug can slow or stop vision loss.
Aurora, ColoradoAges Any age - NCT07294209RecruitingPhase 4
Low-dose tenecteplase for older adults with stroke
This trial tests a lower dose of the clot-busting drug tenecteplase in people aged 70 and older who have had an ischemic stroke. It aims to see if this treatment is safe and effective for older patients when given within 4.5 hours of symptoms starting.
Chongqing, Chongqing MunicipalityAges 70 years+ - NCT04856410Enrolling by invitation
Spaceflight cognitive testing using MRI brain scans
This study looks at how long-duration space travel affects thinking skills, especially memory and spatial navigation, and what changes happen in the brain. It compares astronauts with healthy volunteer “astronaut surrogates” and uses MRI scans to measure brain function.
Philadelphia, PennsylvaniaAges Any age - NCT06575530RecruitingPhase 4
Remimazolam for sedation after non-cardiac surgery
This trial tests a sedative called remimazolam besylate in patients who need a breathing tube and light sedation after non-cardiac surgery. The goal is to see if it works well and is safe.
Beijing, Beijing MunicipalityAges 18–64 - NCT06539208RecruitingPhase 1/Phase 2
Study of YOLT-201 for transthyretin amyloidosis with nerve or heart damage
This trial tests an experimental gene-editing medicine called YOLT-201 for people with a type of amyloidosis that damages nerves or the heart. It aims to see if one or two doses can safely stop the disease from getting worse.
Beijing, Beijing MunicipalityAges 18–80
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,406 recruiting neurology studies from the U.S. registry right now, out of 19,323 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.