Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,406 recruiting studies in this area right now.
By phase
- Not applicable9,740
- Phase 2783
- Phase 1576
- Phase 3534
- Phase 4342
- Phase 1/Phase 2307
- Phase 2/Phase 3124
Top conditions
- Stroke841
- Parkinson Disease427
- Alzheimer Disease342
- Multiple Sclerosis341
- Dementia227
- Ischemic Stroke201
- Epilepsy197
- Obstructive Sleep Apnea156
- Insomnia154
- Spinal Cord Injuries153
- Traumatic Brain Injury150
- Sarcopenia149
- Acute Ischemic Stroke138
- Cerebral Palsy131
- Mild Cognitive Impairment130
- Migraine113
- Pain Management113
- Amyotrophic Lateral Sclerosis108
Leading sponsors
- Beijing Tiantan Hospital133
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing93
- VA Office of Research and Development92
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California681
- Massachusetts299
- New York292
- Florida275
- Texas265
- Maryland246
- Arizona212
- Alabama210
- Illinois188
- Pennsylvania177
Recruiting studies12,404 total
- NCT05991193Recruiting
Study for lung cancer with brain spread and EGFR mutation
This trial tests a treatment for people with advanced non-small cell lung cancer that has spread to the brain or spine. It is for those whose cancer has a specific EGFR mutation (19Del or L858R) and who have not yet received treatment for their advanced cancer.
Changsha, HunanAges 18 years+ - NCT05996653Recruiting
CEST in low-grade glioma brain tumor study
This study uses a special MRI scan called CEST to look at low-grade brain tumors. It may help doctors learn more about these tumors without needing as many invasive tests. You may join if you have a low-grade glioma and haven't needed treatment yet.
Toronto, OntarioAges 12 years+ - NCT06540300Enrolling by invitation
Brain stimulation for non-suicidal self-injury
This study tests whether a gentle brain stimulation technique called repetitive transcranial magnetic stimulation (rTMS) can help reduce self-harm urges and behaviors. It is for people who have non-suicidal self-injury (when you hurt yourself on purpose without wanting to die).
Nanjing, JiangsuAges 10–55 - NCT06529055Enrolling by invitation
Caffeine and nicotine pouch effects on exercise and brain function
This trial tests how caffeine and nicotine pouches affect your body during exercise, including heart function, thinking, and behavior. It looks at short bursts of high-intensity activity in healthy men who already exercise regularly.
Hattiesburg, MississippiAges 21–40 - NCT06527183Recruiting
Fibromyalgia and small fiber nerve study
This study looks at whether people with fibromyalgia or long-term chronic pain have damage to the small nerve fibers in their skin. Understanding this could help develop better treatments.
Boulogne-BillancourtAges 18 years+ - NCT06528730Recruiting
Study on new surgical guidelines for cervical myelopathy in Chinese patients
This trial is testing a new set of surgical criteria for people of Chinese ethnicity with a condition called degenerative cervical myelopathy (a spinal cord problem in the neck). It aims to see if these criteria can better identify who should have surgery.
Hong KongAges 45 years+ - NCT06002477RecruitingEarly Phase 1
Attention study in sickle cell disease
This trial tests a medication to see if it can improve attention in people with sickle cell disease. It may help with thinking and focus.
Nashville, TennesseeAges 55 years+ - NCT06622889Enrolling by invitation
Can changing how you see aging help memory?
This study tests whether changing how older adults think about aging can help with memory concerns. If you are 60+ and feel your memory or thinking is declining (but tests are normal), you may be able to join.
Beijing, Beijing MunicipalityAges 60 years+ - NCT05600660RecruitingPhase 2
Testing a new combo treatment for newly diagnosed brain lymphoma
This trial tests a combination of orelabrutinib, rituximab, and methotrexate in people with newly diagnosed primary CNS lymphoma (a lymphoma mainly in the brain/spinal fluid). The goal is to see how well the treatment works and how safely it can be given.
Hanzhou, ZhejiangAges 18–75 - NCT06512571Recruiting
Heart changes in Fabry disease: an observational study
This study looks at people with Fabry disease, a genetic condition that can cause the heart muscle to thicken. Researchers want to understand how the heart's blood vessels change over time, which may help improve care for Fabry disease.
BeijingAges 18 years+ - NCT06980636RecruitingPhase 4
Shengmai liquid for long covid fatigue trial
This trial tests if a traditional Chinese medicine, Shengmai Liquid, can help reduce fatigue in people with long COVID. It is for adults aged 18 to 75 who feel tired for a long time after a COVID infection.
Beijing, ChinaAges 18–75 - NCT02889016Recruiting
Markers study for children with PANS and healthy controls
This study looks at physical, immune, and brain-related “markers” in children with PANS and compares them with healthy children. It may help doctors understand what is happening in PANS and how to recognize it more clearly early on.
Palo Alto, CaliforniaAges 4–18 - NCT06991062Recruiting
Brain stimulation and smoking: finding personalized treatments
This study tests whether a non-invasive brain stimulation technique (rTMS) can help people who smoke reduce cravings or change smoking behavior. You'll also have your brain activity recorded with a cap (EEG) and do some vaping tasks.
Houston, TexasAges 21–60 - NCT05566496Recruiting
MRI study of different tic disorder types
This study uses MRI (a type of body scan) to look at differences between types of tic disorders in children. It may help doctors better understand what’s happening in conditions like Tourette syndrome and chronic tic disorders.
TaipeiAges birth–18 years - NCT07100171RecruitingEarly Phase 1
GM101 injection for advanced Parkinson's disease
This trial tests an investigational gene therapy injection called GM101 for people with advanced Parkinson's disease whose symptoms are not well controlled by standard medications. The study will see if this treatment can help improve movement and quality of life.
ChangshaAges 40–70 - NCT02714387Recruiting
Study of serious complications from non-traumatic blood vessel brain problems
This study follows people who have non-injury (non-traumatic) blood-vessel-related problems in the brain to understand serious complications. It may help researchers identify risks and improve care over time.
AngersAges 15 years+ - NCT06018519Recruiting
Measuring outcomes for creatine transporter deficiency
This study aims to find the best ways to measure how creatine transporter deficiency (CTD) affects people. It includes both males and females with CTD, as well as healthy volunteers, to compare results and develop better tests.
BronAges 2–60 - NCT06493812Recruiting
Comparing two tissue patches for pituitary tumor surgery
This trial compares two types of tissue patches (from the thigh or temple) used to repair the floor of the skull after pituitary tumor surgery. It helps prevent brain fluid leaks after the operation.
ZagrebAges 18 years+ - NCT06493669Recruiting
Immune cells, muscle, and memory in aging
This study looks at how certain immune cells (Treg cells) in your body relate to your muscle strength and thinking skills as you age. It may help researchers understand how to keep older adults' minds sharp.
Zhuhai, GuangdongAges 40–90 - NCT06491082Recruiting
Chemotherapy nerve damage study in solid tumor patients
This study looks at nerve damage (neuropathy) that can happen as a side effect of chemotherapy. It aims to understand how common it is and how it affects people being treated for solid tumors.
DehradunAges 18 years+ - NCT06486038Recruiting
Spinal cord MRI for better neck surgery outcomes
This study uses an MRI of the spinal cord to better understand damage from a narrowed neck canal. It helps doctors improve outcomes for people who are about to have neck surgery.
RozzanoAges 18–80 - NCT06488248Recruiting
Comparing two surgeries for fluid buildup in the brain
This study compares two surgical treatments for normal pressure hydrocephalus (fluid buildup in the brain). It tests whether a less invasive procedure (endoscopic third ventriculostomy) works as well as the standard shunt surgery to improve walking, memory, and bladder control.
BaselAges 40 years+ - NCT07417371Recruiting
Herbal Medicine for Tourette Syndrome in Children
This trial tests a Chinese herbal formula, Pei Tu Ning Feng Tang, to see how it helps children with Tourette syndrome. It uses a brain imaging technique to understand changes in brain pathways.
Dali, YunnanAges 4–15 - NCT06484374Recruiting
AI-robot guided surgery for large basal ganglia bleeding
This trial tests a new, less invasive brain surgery using a robotic arm guided by artificial intelligence (AI) to remove a large blood clot caused by a hemorrhagic stroke in the basal ganglia. It may be an option for people who can have surgery soon after the stroke and were previously independent.
NanjingAges 18 years+
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,406 recruiting neurology studies from the U.S. registry right now, out of 19,323 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.