Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,407 recruiting studies in this area right now.
By phase
- Not applicable9,740
- Phase 2781
- Phase 1578
- Phase 3536
- Phase 4343
- Phase 1/Phase 2306
- Phase 2/Phase 3123
Top conditions
- Stroke841
- Parkinson Disease429
- Multiple Sclerosis345
- Alzheimer Disease341
- Dementia226
- Ischemic Stroke201
- Epilepsy197
- Obstructive Sleep Apnea156
- Spinal Cord Injuries154
- Insomnia152
- Traumatic Brain Injury150
- Sarcopenia149
- Acute Ischemic Stroke137
- Cerebral Palsy131
- Mild Cognitive Impairment129
- Migraine114
- Pain Management113
- Amyotrophic Lateral Sclerosis108
Leading sponsors
- Beijing Tiantan Hospital133
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic98
- Xuanwu Hospital, Beijing93
- VA Office of Research and Development92
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California681
- Massachusetts299
- New York292
- Florida273
- Texas268
- Maryland246
- Arizona214
- Alabama210
- Illinois189
- Pennsylvania175
Recruiting studies12,405 total
- NCT07324278Recruiting
Arm rehab with mirror exercises after stroke
This study tests a new kind of arm exercise that uses a mirror to help your brain recover movement after a stroke. It may help you improve arm function if you have some movement already.
Kaohsiung City, Yanchao DistrictAges 20–80 - NCT07784842Recruiting
Comparing two eye muscle surgeries for large outward deviation
This study compares two surgical techniques for correcting large-angle outward eye deviation (exotropia). It aims to see which method is more effective and better maintains eye alignment when looking sideways.
Minya, Minya GovernorateAges Any age - NCT07784088Recruiting
Wireless brain implant for tetraplegia
This trial tests a new implantable brain-computer interface designed to help people with tetraplegia (paralysis of arms and legs) control devices using their thoughts. It may help improve independence and quality of life.
BeijingAges 18–65 - NCT06948162Recruiting
Dental MRI for routine dental care
This study tests whether a special MRI machine can take detailed images of teeth and jaws for routine dental care. It may help find problems without using X-rays.
Minneapolis, MinnesotaAges 18 years+ - NCT07785011Recruiting
Sensory integration for gross motor and balance in children with Down syndrome
This study tests whether sensory integration therapy helps improve gross motor skills and balance in children with Down syndrome. It focuses on kids aged 3-5 who can stand alone and have specific IQ and sensory issues, while excluding those with heart problems, severe cognitive issues, recent leg surgery, obesity, or hip problems.
CairoAges 3–5 - NCT06974526RecruitingPhase 2
Study of a dissolvable implant for recovery after ACL surgery
This study tests whether a dissolvable implant that releases a medication called oxandrolone can improve recovery after ACL surgery. Oxandrolone may help strengthen the new ligament and speed up healing.
Fortaleza, CearáAges 18–60 - NCT07716813Recruiting
Breast milk or sugar water for pain during heel prick in babies
This study tests whether giving breast milk or sugar water (10% or 20% dextrose) just before a routine heel prick can reduce pain and keep your baby's heart rate and oxygen levels more stable. It is designed for moderately premature babies in the NICU.
MersinAges 7 months–3.1 years - NCT07365917Recruiting
Core exercise for neck nerve pain
This study tests whether core stabilization exercises (exercises to strengthen your trunk and back) can help reduce pain and improve function in people with cervical radiculopathy (a pinched nerve in the neck that causes arm pain and numbness). If you're between 35 and 50, have had neck pain for over six weeks, and your symptoms fit, you may be eligible.
GizaAges 35–50 - NCT07785999Recruiting
Wearable ring sensor for diagnosing sleep apnea in adults
This study tests whether a wearable ring sensor can help diagnose obstructive sleep apnea (a condition where breathing stops during sleep) compared to the standard in-lab sleep test. If you have suspected sleep apnea and are generally healthy, this study might help you get a simpler and more convenient diagnosis.
Pantai Valley, Kuala LumpurAges 18 years+ - NCT07786194Recruiting
Balance training for older adults with type 2 diabetes
This study tests a balance training program to see if it improves balance and body awareness in people with type 2 diabetes who are 60 or older. It may help you move better and prevent falls.
Edegem, AntwerpenAges 60 years+ - NCT07784946Recruiting
A sleep intervention for people with mild cognitive impairment
This study tests a behavioral sleep intervention for people with mild cognitive impairment or mild dementia. It aims to improve sleep and overall well-being. You may qualify if you have mild cognitive impairment and sleep problems.
Kowloon, Hung HomAges 18 years+ - NCT07786116Recruiting
Gut bacteria in Parkinson's disease and related conditions
This study looks at how certain gut bacteria (methanogens) are involved in the progression of Parkinson's disease and related conditions. It aims to understand the connection between gut health and brain health, which may lead to better treatments.
Cambridge, CB2Ages 55 years+ - NCT07723300Recruiting
Self-guided arm therapy for stroke recovery
This trial tests a self-supervised arm therapy program for people who had a stroke at least two weeks ago. It aims to improve use of the weaker arm through intensive practice at home.
Columbus, OhioAges 18–85 - NCT07299019RecruitingPhase 3
Study of orelabrutinib for secondary progressive MS
This study tests an oral medication called orelabrutinib for people whose multiple sclerosis has changed from relapsing-remitting to secondary progressive. The goal is to see if it can slow down disability worsening that happens even without relapses.
Phoenix, ArizonaAges 18–60 - NCT07713121Recruiting
Keeping blood pressure up during surgery to prevent confusion in older adults
This trial tests whether keeping blood pressure at 85 mmHg or higher during surgery can reduce confusion (delirium) after surgery. It is for older adults with high blood pressure who are having non-cardiac surgery.
HamburgAges 65 years+ - NCT05702645Recruiting
Down syndrome long-term study after leukemia treatment
This study follows children and young adults with Down syndrome who have survived acute leukemia (ALL or AML) to learn about their longer-term health after treatment ends. It may help families and doctors understand what health problems to watch for and how to provide better follow-up care.
Birmingham, AlabamaAges 6–39 - NCT02998229Recruiting
Device trial for wide-neck brain aneurysms at branch points
This trial studies an in-the-aneurysm device placed through a blood vessel to treat certain wide-neck brain aneurysms. It may help prevent aneurysm complications and reduce the risk of needing other procedures, but eligibility depends heavily on your aneurysm shape and health.
Los Angeles, CaliforniaAges 18–75 - NCT07385430RecruitingPhase 1
Study of LGW16-03 to highlight nerves during surgery
This trial tests a dye called LGW16-03 that may help surgeons see nerves more clearly during open surgery. It is for people who are already scheduled for surgery where a major nerve will be exposed.
Lebanon, New HampshireAges 18 years+ - NCT06168071Enrolling by invitation
Nerve stimulation in children during EEG monitoring
This trial tests if gentle nerve stimulation through the ear can help diagnose or treat seizures in children. It is for children who are already in the hospital for an EEG to monitor brain activity.
St Louis, MissouriAges 7–18 - NCT07622589Enrolling by invitation
How stress affects your body during market and news volatility
This study tracks how financial market changes, work stress, and news exposure affect your body's stress response using a wearable device and smartphone app. Researchers want to understand the connection between stress and physical health markers during uncertain times.
New York, New YorkAges 18 years+ - NCT07626411RecruitingPhase 3
Blood Thinner Study for Irregular Heartbeat
This study tests a new blood thinner to prevent strokes and blood clots in people with atrial fibrillation (a common heart rhythm problem). You may qualify if you have atrial fibrillation and at least one risk factor for stroke, or if you've never taken a blood thinner before.
Dothan, AlabamaAges 18 years+ - NCT06088810Recruiting
Can music improve sleep for people with dementia?
This study tests whether listening to music can help people with dementia sleep better. You and a caregiver will participate together.
Durham, North CarolinaAges 18–100 - NCT07785362Enrolling by invitation
Brain stimulation for teens with fibromyalgia or chronic pain
This study tests a non-invasive brain stimulation technique to see if it can reduce pain in teenagers and young adults with fibromyalgia or other long-lasting muscle and bone pain that hasn't responded to usual treatments. It aims to help calm overactive pain signals in the brain.
Genova, GEAges 10–21 - NCT07428447Recruiting
Skin test to predict Parkinson's risk in essential tremor
This study uses a skin biopsy to check for a protein linked to Parkinson's disease. It aims to see if people with essential tremor who have this protein are more likely to develop Parkinson's disease.
Scottsdale, ArizonaAges 50–85
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,407 recruiting neurology studies from the U.S. registry right now, out of 19,231 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.