Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 11,934 recruiting studies in this area right now.
By phase
- Not applicable9,337
- Phase 2764
- Phase 1555
- Phase 3514
- Phase 4340
- Phase 1/Phase 2299
- Phase 2/Phase 3125
Top conditions
- Stroke797
- Parkinson Disease395
- Alzheimer Disease337
- Multiple Sclerosis330
- Dementia224
- Epilepsy192
- Ischemic Stroke190
- Insomnia159
- Traumatic Brain Injury151
- Obstructive Sleep Apnea142
- Spinal Cord Injuries142
- Acute Ischemic Stroke139
- Sarcopenia135
- Mild Cognitive Impairment126
- Cerebral Palsy119
- Pain Management113
- Migraine107
- Fibromyalgia105
Leading sponsors
- Beijing Tiantan Hospital124
- Assistance Publique - Hôpitaux de Paris109
- Riphah International University105
- Mayo Clinic98
- VA Office of Research and Development92
- Xuanwu Hospital, Beijing89
- Hospices Civils de Lyon77
- Johns Hopkins University69
- University of Minnesota63
- Washington University School of Medicine63
Where studies are running
- California655
- Massachusetts304
- New York295
- Florida267
- Texas267
- Maryland248
- Arizona209
- Alabama205
- Illinois183
- Pennsylvania175
Recruiting studies11,934 total
- NCT05033691Recruiting
Osimertinib plus early brain radiation versus osimertinib alone
This trial tests whether starting focused radiation to brain spots early (called SRS) along with osimertinib works better than taking osimertinib alone. It is for people with lung cancer that has an EGFR mutation and has not yet caused major brain symptoms.
JerusalemAges 18–120 - NCT04461444Recruiting
Cohort study for Bardet-Biedl and Alström syndromes
This study follows people with Bardet-Biedl syndrome (BBS) or Alström syndrome (ALMS) to spot early vision, metabolic (body chemistry/energy), and kidney problems. You may be asked to have clinical checks over time to help researchers better understand how these complications develop.
StrasbourgAges 4 months+ - NCT05044520Recruiting
Study of what restless legs feels like
This study looks at the different symptoms and experiences people have with restless legs syndrome. It may help researchers better understand the condition so care can improve for patients.
MontpellierAges 18 years+ - NCT03218332Recruiting
Study of concussion symptoms in professional athletes
This study looks at persistent symptoms after concussions in professional athletes and compares different concussion histories. It aims to understand what contributes to ongoing problems and whether certain patterns can be identified to guide better care.
Toronto, OntarioAges 25–85 - NCT05066763Recruiting
Surveys for people with Parkinson’s and their care partners
This trial is for people with Parkinson’s disease, their care partners, and health professionals who work with people with Parkinson’s. The Parkinson’s Foundation will contact you to collect survey information and may invite you to future research opportunities.
Miami, FloridaAges 18 years+ - NCT05101304Recruiting
European registry for people with amyloidosis
This study collects health information from people who may have amyloidosis or who already have a confirmed diagnosis. It aims to better understand amyloidosis in real-world care across European centers, which can help future patients and treatments.
CréteilAges Any age - NCT05074901Recruiting
Using a health app in France with virtual support
This trial tests whether a digital health app (with “virtual agents,” like guided prompts/support) can improve people’s health outcomes. You may help the study by using the app and completing its questionnaires.
BordeauxAges 18 years+ - NCT04613089Recruiting
Study of Batten disease progress and clinical changes over time
This trial tracks how Batten disease (NCL) affects the body and how symptoms change over time. If you have a confirmed genetic (molecular) diagnosis—especially CLN2 with Brineura treatment—it may help researchers understand disease patterns and care needs.
HamburgAges Any age - NCT04748640RecruitingPhase 2/Phase 3
Gamma Knife treatment for both-sided essential tremor
This study tests a focused radiation procedure (Gamma Knife) to treat the opposite side of the tremor in people with essential tremor. It may help improve tremor-related quality of life if your side that wasn’t treated before is still causing problems.
Toronto, OntarioAges 18 years+ - NCT05124964Recruiting
Quality of life study for newly diagnosed brain germ cell tumors
This study looks at how life quality changes in children and young adults after a new diagnosis of a brain germ cell tumor. It may help doctors understand which supports improve day-to-day well-being.
BeijingAges 3–30 - NCT04306432Recruiting
Check how cognitive tests change after brain tumor radiation
This trial studies how radiation therapy affects thinking and memory in adults with certain brain tumors. It may help doctors understand which patients are more likely to have cognitive side effects and how to measure them over time.
Copenhagen, Capital RegionAges 18–100 - NCT04917705Recruiting
Blood and tissue tests to find markers in muscle and skin disease
This study looks for blood and tissue “biomarkers” (measurable clues in samples) to help diagnose and predict outcomes in inflammatory muscle diseases and systemic sclerosis (a skin/organ condition). If you’re being evaluated for myopathy or early scleroderma, it may help doctors sort out the cause and follow your health more closely.
Strasbourg, Bas-RhinAges 18 years+ - NCT03788512Recruiting
Registry study for recent stroke/TIA with heart artery disease
This study enrolls people who recently had an ischemic stroke or a TIA (a “mini-stroke”) and also have evidence of narrowed heart arteries. It collects information to better understand how brain and heart artery disease occur together and may guide future care.
Beijing, BJAges 18–85 - NCT03571334RecruitingPhase 2
Botox injections for nerve pain after chemotherapy in breast cancer
This trial studies whether botulinum toxin A (Botox) injections can reduce nerve pain caused by chemotherapy in people with breast cancer. It may help if your pain started soon after chemotherapy and fits the trial’s specific nerve-pain pattern.
Milwaukee, WisconsinAges 18 years+ - NCT05237817Recruiting
Links stroke history to accidental adrenal gland findings
This study looks at whether certain accidental adrenal gland growths found on scans are linked to having had a stroke. It may help doctors understand stroke risk factors and how adrenal findings should be interpreted.
BeijingAges 18–100 - NCT04010188Recruiting
Study comparing people with Charcot-Marie-Tooth and healthy controls
This study follows people who have Charcot-Marie-Tooth disease (CMT) and compares them with people without it. It aims to better understand CMT, using both clinical symptoms and genetic test results, which may help future care.
FuzhouAges Any age - NCT04006418Recruiting
Study of spastic paraplegia in patients and healthy controls
This study enrolls people diagnosed with spastic paraplegia and also compares them with healthy people. It helps researchers learn more about the condition and may guide future care or treatments.
FuzhouAges Any age - NCT05208203Recruiting
Registry study for recent stroke and mini-stroke patients
This registry collects information about people recently diagnosed with an acute ischemic stroke or a transient ischemic attack (TIA) at a specific hospital. It helps doctors understand patterns of care and outcomes, which can improve future treatment planning.
Beijing, Beijing MunicipalityAges 18 years+ - NCT05238272Recruiting
tRNS device to improve mirror therapy after stroke
This trial tests a brain-stimulation device (tRNS) paired with precision mirror therapy to improve arm movement after a stroke. It may help people with moderate to mild arm weakness regain more control, but you must meet several safety and health criteria.
TaoyuanAges 35–85 - NCT05257161Recruiting
Carotid stent study comparing two stent positions using brain MRI
This study looks at how well a carotid artery stent works soon after the procedure, using special MRI pictures of the brain. It compares outcomes between stent placement closer to the top versus closer to the bottom of the narrowed area, to see which approach is safer for early brain effects.
NovosibirskAges 45–80 - NCT05260619RecruitingPhase 2
Lenalidomide after response for primary brain lymphoma
This trial studies lenalidomide taken after your first treatment has worked for primary central nervous system lymphoma (PCNSL). It aims to help keep the lymphoma from coming back by testing lenalidomide as ongoing “maintenance” treatment.
Seongnam-si, Please SelectAges 19 years+ - NCT02762175Recruiting
Track breathing airway changes after jaw surgery for sleep apnea
This study records how your upper airway changes on scans after a jaw surgery called MMA for obstructive sleep apnea (OSAS). It also looks at how those changes relate to quality of life, which may help doctors better predict who benefits from surgery.
BrugesAges Any age - NCT05250349Recruiting
Ultrasound brain blood flow and thinking in stable heart failure
This trial studies whether a noninvasive ultrasound test of blood flow in the brain, along with memory and thinking questionnaires, can help explain thinking changes in people with stable heart failure. It may help researchers better understand why some people develop cognitive (thinking) difficulties as heart failure progresses.
Krakow, MPAges 18 years+ - NCT05195658Recruiting
Stent vs standard treatment for acute carotid artery stroke
This trial studies whether placing a special device (a micronet-covered stent) can improve treatment of certain acute strokes caused by blockage at the carotid artery “bifurcation” (where the artery splits). It is meant for people who need an urgent, catheter-based procedure to open the blocked vessel.
KrakowAges 18 years+
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 11,934 recruiting neurology studies from the U.S. registry right now, out of 18,325 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.