Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,407 recruiting studies in this area right now.
By phase
- Not applicable9,740
- Phase 2781
- Phase 1578
- Phase 3536
- Phase 4343
- Phase 1/Phase 2306
- Phase 2/Phase 3123
Top conditions
- Stroke841
- Parkinson Disease429
- Multiple Sclerosis345
- Alzheimer Disease341
- Dementia226
- Ischemic Stroke201
- Epilepsy197
- Obstructive Sleep Apnea156
- Spinal Cord Injuries154
- Insomnia152
- Traumatic Brain Injury150
- Sarcopenia149
- Acute Ischemic Stroke137
- Cerebral Palsy131
- Mild Cognitive Impairment129
- Migraine114
- Pain Management113
- Amyotrophic Lateral Sclerosis108
Leading sponsors
- Beijing Tiantan Hospital133
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic98
- Xuanwu Hospital, Beijing93
- VA Office of Research and Development92
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California681
- Massachusetts299
- New York292
- Florida273
- Texas268
- Maryland246
- Arizona214
- Alabama210
- Illinois189
- Pennsylvania175
Recruiting studies12,405 total
- NCT07480252Recruiting
Tecar therapy for leg pain from a pinched nerve
This trial tests whether Tecar therapy (a type of heat treatment) can reduce leg pain caused by a pinched nerve in the lower back. It's for people with one-sided leg pain that has lasted between 6 weeks and 6 months.
Çiğli, İzmirAges 18–65 - NCT07551921Recruiting
Blood Test Validation for Phenylketonuria Monitoring
This study tests a new fingerstick blood test (PheCheck™) designed to help monitor phenylketonuria (PKU), a rare condition affecting how the body processes a protein called phenylalanine. If you or your child has PKU and are already being monitored for it, this study may help improve how your care team tracks the condition.
Chicago, IllinoisAges 1 year+ - NCT06366464RecruitingPhase 3
Study of a drug for sleepiness in Prader-Willi syndrome
This trial tests a medication called pitolisant to see if it helps reduce excessive daytime sleepiness in people with Prader-Willi syndrome. You or your loved one may be able to join if they have a confirmed diagnosis and a caregiver who can regularly help with study tasks.
Los Angeles, CaliforniaAges 6 years+ - NCT07281079RecruitingPhase 3
Testing NNZ-2591 for children with Phelan-McDermid syndrome
This trial tests a new medicine, NNZ-2591, to see if it helps children with Phelan-McDermid syndrome. It is for children aged 3 to 12 who have a specific genetic change (SHANK3) and weigh at least 10 kg.
Birmingham, AlabamaAges 3–12 - NCT05948813RecruitingPhase 2
TY-9591 for EGFR-mutant lung cancer spread to the brain
This phase 2 trial studies TY-9591 in people with advanced non-small cell lung cancer (NSCLC) that has spread to the brain and has specific EGFR mutations. It aims to see whether the medicine can control the cancer in the brain and the rest of the body, without needing immediate brain radiation.
Beijing, Beijing MunicipalityAges 18–80 - NCT07677982Recruiting
Understanding consent and sedation needs for endobronchial ultrasound
This study looks at how well patients understand the consent process and how much sedative medication they need during an endobronchial ultrasound (a scope test to look at the lungs and lymph nodes). It aims to improve care for people undergoing this procedure.
Bursa, BursaAges 18 years+ - NCT07446712Recruiting
Oxygen Therapy for Complex Regional Pain Syndrome
This trial tests whether breathing pure oxygen in a pressurized chamber (hyperbaric oxygen therapy) can help reduce pain from Complex Regional Pain Syndrome (CRPS) Type I. If you have this condition, the therapy may improve your symptoms.
Ostrava, Moravian-Silesian RegionAges 18 years+ - NCT06592014Enrolling by invitationPhase 1/Phase 2
Lithium for Parkinson's: an extension trial
This trial extends a previous study to see if lithium can help Parkinson's symptoms. It's for people who already took part in a related study at the University at Buffalo.
Williamsville, New YorkAges 45–80 - NCT06416657Recruiting
General vs local anesthesia for brain aneurysm treatment
This trial compares general anesthesia (being fully asleep) to local anesthesia (only the area is numbed) during a procedure to treat an unruptured brain aneurysm with a flow diverter. It aims to find which approach is safer and works better.
Beijing, Beijing MunicipalityAges 18–80 - NCT07785960Enrolling by invitation
Sleep tracking with a special patch after night shifts
This trial tests a patch that you wear while sleeping after a night shift to see if it helps you recover and tracks your sleep. You will also wear a sleep tracker on your wrist.
Birmingham, West MidlandsAges 18 years+ - NCT06698796RecruitingPhase 3
Study of dazukibart for ongoing idiopathic inflammatory myopathies
This trial studies the long-term effects of dazukibart in people who completed an earlier study for idiopathic inflammatory myopathies (a group of rare conditions causing muscle inflammation and weakness). It helps researchers understand how well the medicine works over a longer period.
Glendale, ArizonaAges 18 years+ - NCT06860022Recruiting
Sentence Shaping for deaf or hard of hearing children
This trial tests a new way to help children who are deaf or hard of hearing improve their sentence writing skills. It focuses on children who use both spoken English and American Sign Language and need extra help with word order and grammar.
Nashville, TennesseeAges 9–15 - NCT07486869RecruitingPhase 2
Emapalumab study for MDA5-related lung disease
This trial tests if emapalumab can help people with a serious lung condition linked to MDA5 antibodies. It may be an option for those with worsening breathing despite other treatments.
Miami, FloridaAges 18 years+ - NCT07312565Recruiting
Checking for belly aneurysms after brain aneurysm
This study checks if people who had a brain aneurysm (subarachnoid hemorrhage) later develop an abdominal aortic aneurysm, which is a bulge in the main artery in the belly. They will use an ultrasound to look at the abdominal aorta about a year or more after the brain bleed.
LeidenAges 18 years+ - NCT07657949Recruiting
Nerve block for pain after breast reduction surgery
This trial tests a specific nerve block to see if it can reduce pain after breast reduction surgery, possibly helping with recovery and lowering the need for strong painkillers.
Sivas, SivasAges 18–65 - NCT02402244Recruiting
Caring registry study for children and young people with cancer
This study keeps a careful record of children, teens, and young adults with cancer (and some related growths) and may follow them over time. It helps researchers better track outcomes and future contact so care can improve.
Birmingham, AlabamaAges Up to 25 years - NCT01889381RecruitingPhase 2
Transplanting facial and jaw bone using donor tissue
This trial studies a special surgery to replace part of the skull, face, and jaw using donor tissue. It also tests medicines to help your body accept the transplant, aiming to restore function and appearance after serious injury.
Baltimore, MarylandAges 18–65 - NCT07476222Recruiting
Predicting testosterone decline in middle-aged men
This study looks at why testosterone levels drop in men aged 35-59. It may help identify early signs and ways to prevent it.
AndijanAges 35–59 - NCT06871878Recruiting
Physiotherapy with telerehab after stroke
This trial tests a physiotherapy program that includes some sessions done at home using video calls. It aims to see if this extra therapy time can help improve arm and leg movement after a stroke.
BothwellAges 16 years+ - NCT07784751Enrolling by invitationPhase 1/Phase 2
Ultrasound therapy for stroke recovery
This study tests a new treatment that uses ultrasound pulses to help people recover after a stroke. It may improve movement or language abilities.
Taipei, TaiwanAges Any age - NCT07599670RecruitingPhase 1/Phase 2
Safety study of ABBV-1758 injection for Alzheimer's disease
This early-stage trial tests whether ABBV-1758, a new drug given by injection, is safe and effective for people with Alzheimer's disease. The drug targets amyloid, a protein that builds up in the brains of people with Alzheimer's.
Irvine, CaliforniaAges 50–90 - NCT07782216Recruiting
Studying brain proteins after acute brain injury
This study looks at how certain brain proteins (called biomarkers) behave in the blood after an acute brain injury. The goal is to see if these proteins can help doctors quickly assess the severity of the injury. Participation involves giving blood samples at specific times after your injury.
Pécs, BranyaAges 18 years+ - NCT07178210Recruiting
Robotic surgery for lymphatic drainage in Alzheimer's disease
This study tests a new robotic-assisted surgery to improve drainage of lymph fluid in the neck, which may help slow the progression of Alzheimer's disease. It is for people with mild to moderate Alzheimer's who have specific biomarkers.
Palo Alto, CaliforniaAges 50 years+ - NCT07641179RecruitingPhase 2
Testing MAR002 for Acromegaly (a Pituitary Tumor Condition)
This study tests a new drug called MAR002 to treat acromegaly, a hormone disorder caused by a pituitary tumor that makes too much growth hormone. The drug is designed to help lower hormone levels and improve symptoms.
Phoenix, ArizonaAges 18–75
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,407 recruiting neurology studies from the U.S. registry right now, out of 19,231 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.