Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,407 recruiting studies in this area right now.
By phase
- Not applicable9,740
- Phase 2781
- Phase 1578
- Phase 3536
- Phase 4343
- Phase 1/Phase 2306
- Phase 2/Phase 3123
Top conditions
- Stroke841
- Parkinson Disease429
- Multiple Sclerosis345
- Alzheimer Disease341
- Dementia226
- Ischemic Stroke201
- Epilepsy197
- Obstructive Sleep Apnea156
- Spinal Cord Injuries154
- Insomnia152
- Traumatic Brain Injury150
- Sarcopenia149
- Acute Ischemic Stroke137
- Cerebral Palsy131
- Mild Cognitive Impairment129
- Migraine114
- Pain Management113
- Amyotrophic Lateral Sclerosis108
Leading sponsors
- Beijing Tiantan Hospital133
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic98
- Xuanwu Hospital, Beijing93
- VA Office of Research and Development92
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California681
- Massachusetts299
- New York292
- Florida273
- Texas268
- Maryland246
- Arizona214
- Alabama210
- Illinois189
- Pennsylvania175
Recruiting studies12,405 total
- NCT00271622Recruiting
Screening test for child or adult brain and behavior patterns
This study uses a structured check-up to learn about how someone’s thinking, behavior, and development may differ from typical patterns. It involves an interview and possibly medical, nervous-system, and blood or urine tests to understand what kinds of issues might be present.
Bethesda, MarylandAges 1 month+ - NCT07276711Recruiting
Protecting brain during TAVR with EmStop device
This trial tests a new device (EmStop) that helps protect your brain during TAVR (a type of heart valve replacement). The device is placed in arteries to catch any debris that might break loose during the procedure, potentially reducing the risk of stroke.
Thousand Oaks, CaliforniaAges 22 years+ - NCT07687095Recruiting
Music during breast surgery and anesthesia use
This trial tests whether listening to music during breast surgery can reduce the amount of anesthesia medication needed. If you're having breast surgery and can use headphones, this study may help make your experience more comfortable.
Bursa, BursaAges 18–70 - NCT06376760Recruiting
Anesthetic dose changes for insomnia patients during endoscopy
This study looks at how insomnia affects the amount of anesthesia needed during a digestive endoscopy. It compares people with insomnia to those with normal sleep to see if dosage adjustments are needed.
Beijing, Beijing MunicipalityAges 18–64 - NCT04685772Recruiting
Medrol Dose Pack for new concussion headache relief
This trial tests whether a Medrol “dose pack” (a short course of steroid medicine taken by mouth) can reduce acute headache pain after a concussion. It may help people whose concussion headaches are frequent and severe soon after injury.
Manhasset, New YorkAges 18 years+ - NCT07628283Recruiting
Telemedicine stroke prevention program for rural elderly adults
This study tests whether using telemedicine (remote health technology) combined with care at a local village clinic can better prevent strokes and manage stroke risk in older adults living in rural areas. Participants will receive ongoing health monitoring and support tailored to their stroke risk factors.
Suqian, JiangsuAges 65 years+ - NCT07576036Enrolling by invitation
Study of severe low sodium and brain safety during treatment
This is a retrospective study (meaning researchers look back at medical records) of patients who had very low sodium levels in their blood when admitted to the hospital. Researchers want to understand the link between how quickly doctors correct low sodium and a rare brain condition called osmotic demyelination syndrome.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT07651631Recruiting
Brain Bleeding Surgery Registry and Treatment Study
This study tracks patients who have had sudden, severe bleeding in the brain and received minimally invasive surgery (a less-invasive surgical approach) to treat it. Researchers want to understand outcomes and improve treatment for this serious condition.
Atlanta, GeorgiaAges 18 years+ - NCT06976268RecruitingPhase 2/Phase 3
Testing BHV-8000 for early Parkinson's disease
This study tests a new once-daily pill called BHV-8000 in people who were recently diagnosed with early Parkinson's disease and are not yet on medication. The goal is to see if it can slow the progression of symptoms and improve quality of life.
Birmingham, AlabamaAges 40–80 - NCT06365658Recruiting
Cognitive function in healthy adults
This study looks at how thinking and memory work in healthy adults and compares them to people with certain health conditions. As part of the control group, you will help researchers understand normal cognitive function.
Gdansk, Pomeranian VoivodeshipAges 18 years+ - NCT07109817RecruitingPhase 2
Desloratadine to prevent nerve damage from taxane chemo in breast cancer
This trial tests if the allergy medicine desloratadine can prevent nerve damage (numbness, tingling, pain) caused by taxane chemotherapy in people with early-stage breast cancer. Taking desloratadine daily during chemo may help protect your nerves.
The Bronx, New YorkAges 18 years+ - NCT06585787RecruitingPhase 3
Testing KarXT for psychosis in Alzheimer’s disease
This study tests an investigational medication (KarXT) for treating psychosis—hallucinations or delusions—in people with Alzheimer’s disease. It aims to see if the drug can reduce these symptoms safely and effectively.
Chandler, ArizonaAges 55–90 - NCT06976788Recruiting
Healthy volunteers needed for brain imaging study on epilepsy
This trial is creating a database of brain scans from healthy people to improve understanding of epilepsy. You would have one PET scan of your brain to help researchers develop new imaging methods.
MarseilleAges 18–65 - NCT06941701Recruiting
Fatigue's effect on thinking and movement together
This study looks at how being physically tired affects your ability to think and perform tasks at the same time. It may help understand why dual-tasking gets harder when you're fatigued.
IslamabadAges 18–30 - NCT06937398Recruiting
Survey on brain monitoring during kids' anesthesia
This study surveys parents and older children to understand their views on using EEG brain monitoring during anesthesia. It aims to improve care for children having planned surgeries.
SingaporeAges 12 years+ - NCT06934213Recruiting
Visual processing study for healthy adults
This study tests how the brain processes visual information. It's for healthy adults with normal color vision and good eyesight.
Boston, MassachusettsAges 18 years+ - NCT06923462Recruiting
VoiceLove app for ICU patients on a ventilator
This study tests a special app called VoiceLove that helps patients in the ICU who are on a breathing machine communicate with their family and care team. The goal is to reduce confusion and improve connection and satisfaction for everyone involved.
Nashville, TennesseeAges 18 years+ - NCT06884488Recruiting
Effects of brain stimulation on throat muscles
This study tests if two types of brain stimulation (repetitive transcranial magnetic stimulation and paired associative stimulation) can affect the brain area that controls swallowing. It aims to understand how these stimulation methods work in healthy volunteers.
ManchesterAges 18 years+ - NCT06870149Recruiting
Dance program to improve mobility in older adults at risk
This study tests whether a structured dance program (called GERAS DANCE) can help older adults who are frail or at risk of losing mobility. You would attend dance sessions at the YMCA twice a week, and researchers will see if it improves your walking and daily function.
Hamilton, OntarioAges 65–100 - NCT06627426Recruiting
Virtual reality for helping patients understand brain surgery
This trial uses virtual reality to help you better understand your upcoming brain surgery, such as for an aneurysm, abnormal blood vessels, or a tumor. It aims to improve how information is given before surgery.
BaselAges 18–75 - NCT05544799Recruiting
Study of people’s experiences after nearly dying
This study looks at what patients feel and remember after a serious life-threatening medical event, such as surviving cardiopulmonary resuscitation or intensive ICU care. It may help doctors and hospitals better understand patients’ emotional and recovery experiences after near-death moments.
SeoulAges 19 years+ - NCT05539378Enrolling by invitation
Study how sleep affects the brain’s self-cleaning process
This study looks at whether improving or tracking sleep changes how the brain “clears” waste. It may help researchers understand sleep’s role in brain health and how to support it.
ZurichAges 50–80 - NCT05036629Recruiting
Brain MRI and brain-activity testing in healthy and patients
This study fine-tunes MRI (brain imaging) methods and checks brain signals during testing in both healthy people and people with medical conditions. It may help improve how doctors use MRI to understand brain and nervous system changes.
La TroncheAges 18 years+ - NCT03232463Enrolling by invitation
Testing an advanced MRI scan in everyday clinic care
This study checks whether a more advanced MRI scan can be safely used in regular clinical practice. If you need an MRI for a health problem, the study may help your care team use the newer scan approach.
Santa Monica, CaliforniaAges 18–65
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,407 recruiting neurology studies from the U.S. registry right now, out of 19,231 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.