Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 11,934 recruiting studies in this area right now.
By phase
- Not applicable9,337
- Phase 2764
- Phase 1555
- Phase 3514
- Phase 4340
- Phase 1/Phase 2299
- Phase 2/Phase 3125
Top conditions
- Stroke797
- Parkinson Disease395
- Alzheimer Disease337
- Multiple Sclerosis330
- Dementia224
- Epilepsy192
- Ischemic Stroke190
- Insomnia159
- Traumatic Brain Injury151
- Obstructive Sleep Apnea142
- Spinal Cord Injuries142
- Acute Ischemic Stroke139
- Sarcopenia135
- Mild Cognitive Impairment126
- Cerebral Palsy119
- Pain Management113
- Migraine107
- Fibromyalgia105
Leading sponsors
- Beijing Tiantan Hospital124
- Assistance Publique - Hôpitaux de Paris109
- Riphah International University105
- Mayo Clinic98
- VA Office of Research and Development92
- Xuanwu Hospital, Beijing89
- Hospices Civils de Lyon77
- Johns Hopkins University69
- University of Minnesota63
- Washington University School of Medicine63
Where studies are running
- California655
- Massachusetts304
- New York295
- Florida267
- Texas267
- Maryland248
- Arizona209
- Alabama205
- Illinois183
- Pennsylvania175
Recruiting studies11,934 total
- NCT04192656RecruitingPhase 4
PAP treatment for sudden hearing loss with sleep apnea
This trial tests whether using PAP (a breathing device for sleep apnea) can improve sudden hearing loss that happens alongside obstructive sleep apnea. It may help by reducing stress on the body during sleep and supporting hearing recovery.
Beijing, Beijing MunicipalityAges 18–70 - NCT03887663Recruiting
Chinese Parkinson’s disease patient registry
This study is a registry that collects information from people with Parkinson’s disease to better understand the condition. You may help researchers learn about patterns of symptoms and care over time.
Changzhi, HunanAges Any age - NCT01840930Recruiting
Study of severe cerebral palsy in children
This study looks at children ages 2 to 10 who have severe, long-term cerebral palsy to better understand this condition. It may help clinicians learn what to expect and how to support children with the most significant mobility needs.
BronAges 2–10 - NCT04198246Recruiting
Chinese essential tremor registry study
This study is a registry for people diagnosed with essential tremor, helping doctors collect and compare information over time. It may help improve understanding of essential tremor and guide future care.
Changsha, HunanAges Any age - NCT04237675Recruiting
Study of MS relapses after surgery
This study looks at relapses (new or worsening MS symptoms) after surgery in people with multiple sclerosis (MS). It may help researchers understand what triggers relapse after surgery so better care can be planned.
Athens, AtticaAges 18–70 - NCT02362685Recruiting
Metabolic exercise testing study
This study is about doing a breathing-and-heart performance test while you exercise to better understand how your body uses energy. You may join if you’re referred for this type of test and can safely complete it.
BrestAges 5 years+ - NCT03360227Recruiting
Registry after heart device implantation planning
This is a registry study that records information from people before they get a heart-related device implanted. It may help doctors understand how the team’s tests and planning relate to the procedure and outcomes later on.
DüsseldorfAges 18–80 - NCT01703429Recruiting
Alternative care program for people with multiple sclerosis
This study looks at how a complementary or alternative care approach affects people living with multiple sclerosis. It may help to understand whether this type of program improves symptoms or quality of life over time.
Kenmore, WashingtonAges 18–100 - NCT04316039RecruitingPhase 2/Phase 3
Radiation alone or with temozolomide for brain tumor after surgery
This trial compares standard radiation therapy versus radiation plus a chemotherapy medicine called temozolomide in people with a newly diagnosed low-grade (WHO grade II) brain glioma after surgery. It’s designed to see if adding temozolomide improves outcomes while managing side effects.
Chengdu, SichuanAges 18–70 - NCT04347785Recruiting
Study nerve effects after carotid surgery done with local anesthesia
This trial looks at what factors predict new or worsening nerve symptoms after a carotid endarterectomy (a surgery to clear plaque in the neck artery) when done with regional anesthesia. It may help doctors better anticipate and prevent neurologic problems during this procedure.
PortoAges 18–100 - NCT04399707Recruiting
Nerve-pain device study for pain after C-section
This study tests whether a small skin electrical nerve stimulator (called TENS) can reduce pain after a planned or not-urgent C-section. You may be more likely to have less pain and use fewer pain medicines if the TENS helps you.
Honolulu, HawaiiAges 18 years+ - NCT01195558Recruiting
Registry survey for people who are blind and have sleep problems
This study is a registry survey that collects information about sleep problems and daytime sleepiness. It may help researchers better understand sleep issues in people who are blind and plan future studies or treatments.
Washington D.C., District of ColumbiaAges Any age - NCT04454892Recruiting
Study of ALS symptoms and disease course
This study watches people with ALS over time to better understand how symptoms change and what features show up. It may help future care and treatments by improving doctors’ understanding of ALS’s natural course.
BeijingAges Any age - NCT04499755RecruitingPhase 3
Nucleo CMP Forte for moderate to severe brain injury in children
This trial studies whether a supplement called Nucleo CMP Forte can improve outcomes after a moderate or severe traumatic brain injury in children. It may help families see if adding this treatment makes recovery better and safer.
TantaAges Up to 18 years - NCT03149705Recruiting
Study group of adults with ischemic stroke
This study looks at adults who have had an ischemic stroke confirmed on MRI and a blockage in a major brain artery. Researchers want to understand stroke care in people who can receive standard clot-busting treatment (thrombolysis) and/or clot removal (thrombectomy).
BronAges 18 years+ - NCT02836158RecruitingPhase 2/Phase 3
Test drug plus spinal chemotherapy for older PCNSL
This trial studies whether adding R-IDARAM and medication delivered into the spinal fluid can improve treatment for primary central nervous system lymphoma (PCNSL) in newly diagnosed older adults. It may help by targeting lymphoma cells in the brain, covering membranes, and spinal fluid.
Beijing, Beijing MunicipalityAges 60–75 - NCT04360200Recruiting
Study of thinking changes in older adults
This trial looks at people over age 50 who have mild thinking or memory problems but do not have dementia by standard clinical criteria. It tests how these early changes are characterized and measured using exams such as blood tests and brain scans, which may help improve understanding and future care.
Guangzhou, GuangdongAges 50 years+ - NCT02657785RecruitingPhase 2/Phase 3
Treating newly diagnosed brain lymphoma with added medicines into CSF
This trial studies a treatment plan for people with newly diagnosed non-Hodgkin lymphoma that has spread to the brain and covering tissues (meninges). It combines medicines given through the bloodstream with immunotherapy placed into the fluid around the brain (CSF) to improve control of the lymphoma.
Beijing, Beijing MunicipalityAges 18–75 - NCT00178724Recruiting
Spinal cord injury registry for people after a first trauma
This trial is a registry that collects information about people 18 and older who have a first spinal cord injury caused by trauma. By sharing details, you help researchers better understand outcomes and care needs after these injuries.
Miami, FloridaAges 18 years+ - NCT04616508Recruiting
Online arm movement training for people with Parkinson’s
This study uses online tasks to look at how people with Parkinson’s control reaching movements. You may benefit by contributing to research that could improve understanding and future treatments for movement problems.
Newark, DelawareAges 18–85 - NCT03457831Recruiting
Check a treatment approach for prolonged seizure emergencies
This trial is for adults in the intensive care unit who are having seizures that last at least 5 minutes or keep coming back without fully recovering. It tests a study approach for managing a dangerous seizure emergency and may help doctors improve care for critically ill patients.
AngoulêmeAges 18 years+ - NCT04620642Recruiting
Registry for adults treated with clot-busting or clot removal
This trial is a registry that collects information from adults who were hospitalized for an ischemic stroke and received either clot-busting medicine or a procedure to remove the clot. It may help doctors better understand stroke treatments and outcomes.
LyonAges 18 years+ - NCT04973579Recruiting
Stent plus heart surgery for high risk carotid patients
This trial looks at whether doing carotid artery stenting at the same time as heart surgery is safe and effective for people at high risk of stroke around the time of surgery. It targets people with significant carotid narrowing who also need heart surgery for specific heart problems.
KrakowAges 18 years+ - NCT04665726Recruiting
Natural history study of Usher syndrome hearing and vision changes
This study follows people with Usher syndrome over time to better understand how hearing and vision symptoms change. It may help researchers measure disease progression and support future treatments.
ParisAges Any age
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 11,934 recruiting neurology studies from the U.S. registry right now, out of 18,325 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.