Gastroenterology
Digestive system clinical trials
Conditions of the stomach, intestines, liver, and the rest of the digestive tract. We’re tracking 7,599 recruiting studies in this area right now.
By phase
- Not applicable4,683
- Phase 21,187
- Phase 1568
- Phase 3457
- Phase 1/Phase 2366
- Phase 4228
- Phase 2/Phase 3110
Top conditions
- Colorectal Cancer478
- Pancreatic Cancer287
- Gastric Cancer283
- Hepatocellular Carcinoma256
- Esophageal Cancer189
- Rectal Cancer168
- Breast Cancer146
- Crohn Disease134
- Ulcerative Colitis129
- Colon Cancer114
- Hepatocellular Carcinoma (HCC)112
- Liver Cancer99
- Lung Cancer95
- Inflammatory Bowel Diseases94
- Pancreas Cancer91
- Ovarian Cancer89
- Esophageal Squamous Cell Carcinoma86
- Cystic Fibrosis77
Leading sponsors
- Fudan University101
- Sun Yat-sen University85
- Mayo Clinic75
- Second Affiliated Hospital, Zhejiang University, School of Medicine56
- Chinese University of Hong Kong55
- M.D. Anderson Cancer Center55
- Assistance Publique - Hôpitaux de Paris53
- Sixth Affiliated Hospital, Sun Yat-sen University51
- National Cancer Institute (NCI)49
- National Taiwan University Hospital45
Where studies are running
- California438
- Arizona189
- Texas140
- Alabama129
- Florida128
- New York120
- Massachusetts119
- Maryland88
- Ohio79
- Illinois69
Recruiting studies7,599 total
- NCT07307495Recruiting
Pain relief after back surgery and its effect on recovery
This study tests a new painkiller, oliceridine fumarate, given through a pump after lumbar spine surgery. The goal is to see if it helps the bowels and stomach recover faster compared to standard pain relief.
Xi'an, ShaanxiAges 18–75 - NCT07312890Recruiting
Ultrasound to check stomach fullness in ICU patients
This trial tests whether a bedside ultrasound can measure how full the stomach is in patients on a breathing machine who are receiving liquid nutrition through a tube. If it works, doctors may avoid complications and feed patients more safely.
LyonAges 18 years+ - NCT07309185RecruitingPhase 2
Adebrelimab, famitinib, and irinotecan for advanced stomach cancer
This trial tests a combination of three drugs (adebrelimab, famitinib, and irinotecan) for people with advanced stomach or gastroesophageal junction cancer that got worse after first-line treatment. It may offer a new option if you have already tried standard therapy.
Jinan, ShandongAges 18–75 - NCT07310069Enrolling by invitationPhase 2
Testing a new drug combination for advanced gallbladder cancer
This trial tests a combination of two chemotherapy drugs (gemcitabine and nab-paclitaxel) with two immunotherapy drugs (iparomlimab and tuvorilimab) for people with advanced gallbladder cancer that cannot be removed by surgery. The goal is to see if this combination can help shrink the cancer or slow its growth.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT07314489RecruitingEarly Phase 1
Glucose and enzyme function in chronic pancreatitis
This study looks at how chronic pancreatitis affects blood sugar and digestion. It tests if your body makes enough enzymes and how your sugar control changes over time.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT07309315Recruiting
Testing a bacteria pill to prevent diarrhea from chemotherapy
This trial tests if a pill made from a harmless bacteria can prevent diarrhea caused by certain chemotherapy treatments. It is for people with advanced colorectal cancer or breast cancer who are about to start specific treatments.
Shenzhen, GuangdongAges 18 years+ - NCT07309601Recruiting
Sucrase-isomaltase genes and meal study for IBS
This study looks at how people with irritable bowel syndrome (IBS) handle meals based on their genes for an enzyme that breaks down sugar and starch. It may help explain why some people benefit from a starch- and sugar-reduced diet.
Malmö, Skåne CountyAges 18–70 - NCT07307248Recruiting
Removing a metal stent early vs. standard timing after cyst drainage
This study compares removing a special metal stent early (after 2 weeks) versus waiting the usual 4 weeks in people who had a cyst in their pancreas drained. It is for those whose cyst has shrunk at least 70% after 2 weeks, to see if earlier removal is safe and effective.
Hyderabad, TelanganaAges 18 years+ - NCT07312760Recruiting
Talking therapy for existential distress in advanced cancer
This trial compares a short-term psychodynamic therapy (ORPHYS) with usual care for people with advanced cancer who are struggling with existential distress, such as loss of hope, fear of death, or loneliness. It aims to see if this therapy can help improve emotional well-being.
DüsseldorfAges 18 years+ - NCT07314606Recruiting
Diet plus infliximab for kids with Crohn’s
This study tests if a special diet (called CDED) combined with infliximab (a biologic drug) is more effective than infliximab alone for children with newly diagnosed or relapsed moderate-to-severe Crohn’s disease. It aims to improve gut healing and reduce inflammation.
Vancouver, British ColumbiaAges 9–17 - NCT07312864RecruitingPhase 1/Phase 2
New bioartificial liver for liver failure and small-for-size syndrome
This study tests a new bioartificial liver made from special cells to support people with severe liver problems, including liver failure or when the liver is too small after surgery. It aims to see if it is safe and can help the liver recover.
BeijingAges Any age - NCT07309991Recruiting
Oxygen Levels After Esophageal Cancer Surgery and Healing Complications
This study looks at whether low oxygen levels in the blood after esophageal cancer surgery increases the risk of problems with how the surgery heals. By understanding this connection, doctors may be able to better prevent or treat healing complications.
Guangzhou, GuangdongAges 18–80 - NCT07313007Recruiting
Gut bacteria chemicals in fatty liver disease
This study looks at whether the natural chemicals made by your gut bacteria from the food you eat could affect liver fat and health. If you have MASLD (a fatty liver condition), researchers want to measure these gut-produced substances to better understand the disease.
Pierre-BéniteAges 18–80 - NCT07307703Recruiting
TENS for pain and anxiety after gallbladder surgery
This trial tests whether TENS, a mild electrical therapy, can reduce pain and anxiety after gallbladder removal. If you are having planned gallbladder surgery and are in good health, you may be able to participate.
Niğde, AdanaAges 18 years+ - NCT07310316Recruiting
A trial for variceal bleeding in cavernous transformation of portal vein
This study tests a combined procedure to stop bleeding from enlarged veins in the food pipe (varices) in people with a rare condition called cavernous transformation of the portal vein. The treatment involves blocking the bleeding veins and reducing blood flow to the spleen to prevent future bleeding.
Xi'an, ShaanxiAges 18–75 - NCT07312162Recruiting
Liver cancer health disparities study
This study looks at why some people with liver cancer are diagnosed at a later stage. Researchers want to understand differences in care and outcomes for patients in certain areas of Los Angeles County.
Los Angeles, CaliforniaAges 18 years+ - NCT07307586RecruitingPhase 3
Azvudine for new hepatitis B patients
This study tests a new pill (azvudine) to see if it can cure chronic hepatitis B in people who have never been treated before. It is for those with active infection and elevated liver enzymes.
Zhengzhou, HenanAges 18–65 - NCT07312422RecruitingPhase 1/Phase 2
Low-dose radiation with immunotherapy and standard therapy for advanced pancreatic cancer
This trial combines low-dose radiation with an immunotherapy drug (pucotenlimab) and standard treatment for advanced pancreatic cancer. It aims to see if this triple therapy can help control the cancer without using a PD-1/PD-L1 inhibitor before.
Hangzhou, ZhejiangAges 18–75 - NCT07310888Recruiting
Robotic stomach surgery using a 5th arm
This trial tests a new robotic technique for stomach cancer surgery using an extra robot arm. It may help you recover faster and with fewer complications.
Hong KongAges 18–75 - NCT07309289RecruitingPhase 3
Comparing two drug combos for first-line metastatic colorectal cancer
This trial tests whether a combination of chemotherapy drugs (NALIRIFOX) plus targeted therapy works better than another standard combination (FOLFOX) plus targeted therapy for people with metastatic colorectal cancer who haven't had treatment yet. It aims to find a more effective first treatment option.
ShanghaiAges 18 years+ - NCT07315633Recruiting
Personalized TARE treatment planning for liver cancer
This trial is testing a new computer tool that uses your own scans to plan TARE treatment for liver cancer. The goal is to make the treatment more personalized and effective.
GhentAges 18 years+ - NCT07313579Recruiting
Heated chemotherapy for stomach cancer during surgery
This trial tests giving heated chemotherapy directly into the belly during surgery for stomach cancer. It might help people with cancer that has spread to the lining of the belly but not to other organs.
KyivAges 18–80 - NCT07313293Recruiting
Foot reflexology for nausea after weight-loss surgery
This trial tests if foot reflexology can help reduce nausea after sleeve gastrectomy (a type of weight-loss surgery). You may join if you are scheduled for this surgery and do not have foot problems or take strong pain medications.
La Roche-sur-YonAges 18 years+ - NCT07312292RecruitingPhase 2
Radioembolization with angiotensin II to boost tumor radiation dose
This trial tests whether adding a drug called angiotensin II (which tightens blood vessels in healthy tissue) during radioembolization can deliver more radiation directly to liver tumors. It is for people who have liver tumors (either primary or that have spread to the liver) and are scheduled for radioembolization.
Utrecht, UtrechtAges 18 years+
Common questions
- How many digestive system clinical trials are recruiting?
- Clin2 is tracking 7,599 recruiting gastroenterology studies from the U.S. registry right now, out of 11,991 we cover in this area in total.
- What does “Digestive system” cover here?
- Conditions of the stomach, intestines, liver, and the rest of the digestive tract. We group each study into digestive system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a digestive system trial near me?
- Use the search to filter digestive system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.