Gastroenterology
Digestive system clinical trials
Conditions of the stomach, intestines, liver, and the rest of the digestive tract. We’re tracking 7,916 recruiting studies in this area right now.
By phase
- Not applicable4,936
- Phase 21,188
- Phase 1583
- Phase 3465
- Phase 1/Phase 2396
- Phase 4237
- Phase 2/Phase 3111
Top conditions
- Colorectal Cancer493
- Gastric Cancer298
- Pancreatic Cancer292
- Hepatocellular Carcinoma284
- Esophageal Cancer191
- Rectal Cancer176
- Breast Cancer148
- Crohn Disease144
- Ulcerative Colitis140
- Colon Cancer115
- Inflammatory Bowel Diseases108
- Hepatocellular Carcinoma (HCC)107
- Liver Cancer101
- Lung Cancer99
- Pancreas Cancer94
- Esophageal Squamous Cell Carcinoma89
- Ovarian Cancer88
- Cystic Fibrosis78
Leading sponsors
- Fudan University104
- Sun Yat-sen University91
- Mayo Clinic75
- Chinese University of Hong Kong60
- M.D. Anderson Cancer Center58
- Second Affiliated Hospital, School of Medicine, Zhejiang University57
- Assistance Publique - Hôpitaux de Paris55
- Sixth Affiliated Hospital, Sun Yat-sen University50
- National Taiwan University Hospital49
- Cancer Institute and Hospital, Chinese Academy of Medical Sciences48
Where studies are running
- California461
- Arizona174
- Texas148
- Florida135
- Massachusetts127
- Alabama123
- New York123
- Maryland87
- Ohio80
- Pennsylvania72
Recruiting studies7,916 total
- NCT07565454Recruiting
Survey about liver and pancreas surgery training programs
This study asks surgeons and surgical trainees about their experiences in liver, pancreas, and bile duct surgery fellowship programs. The survey helps improve training and understand what works best in these specialized programs.
Dallas, TexasAges Any age - NCT07565714Recruiting
AI-Guided Imagery Therapy for Anxiety and Childhood Memories
This research tests a new computer-assisted therapy that helps people with anxiety process difficult childhood memories involving parental criticism. The AI guides you through imagining and reworking these memories to reduce anxiety symptoms.
Poznan, WielkopolskaAges 18–35 - NCT07566559Recruiting
Rectal Cancer Treatment Before Surgery Study
This study follows real-world treatment of locally advanced rectal cancer (cancer that has grown into nearby tissues but hasn't spread to distant organs) in patients who receive chemotherapy and/or radiation before surgery. Researchers track how different treatment approaches work to help improve outcomes.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07567131Recruiting
Understanding sun sensitivity in rare porphyria disorders
This study tracks how your body reacts to sunlight if you have erythropoietic protoporphyria (EPP) or X-linked protoporphyria (XLP)—rare genetic conditions that cause painful skin reactions to sun exposure. Researchers will use special devices and daily logs to better understand your symptoms and how light affects your skin.
Boston, MassachusettsAges 12 years+ - NCT07569419RecruitingEarly Phase 1
Testing Linaclotide for Cystic Fibrosis Bowel Function
This early-stage study tests whether a medication called linaclotide can help improve bowel function in people with cystic fibrosis. Researchers will use MRI scans and other tests to see how the medication affects your digestive system.
NottinghamAges 18–65 - NCT07569679RecruitingPhase 2
Combination Chemotherapy and Immunotherapy for Biliary Tract Cancer
This trial tests a combination of chemotherapy drugs given directly into the liver, combined with two immunotherapy/targeted therapy drugs, for people with advanced biliary tract cancer (cancer of the bile ducts or gallbladder). The goal is to shrink tumors and improve survival in patients who have not received prior chemotherapy.
Xi'an, ShaanxiAges 18 years+ - NCT07573371Recruiting
Understanding bowel changes after rectal cancer surgery
This study helps doctors better understand and treat bowel control problems that can happen after rectal cancer surgery or other rectal treatments. If you've had this surgery or treatment, the study team wants to learn more about your recovery and test new ways to help.
AalborgAges 18 years+ - NCT07574515Recruiting
Nasogastric Tube for Small Bowel Blockages
This trial tests whether placing a thin feeding tube through the nose into the stomach helps reduce complications in patients with small bowel obstruction (a blockage in the small intestines). Researchers want to see if this tube improves outcomes and reduces symptoms like nausea and vomiting.
LinköpingAges 18 years+ - NCT07574970Recruiting
Preventing pancreatitis after endoscopic bile duct procedures
This study tests whether combining a rectal anti-inflammatory medication (indomethacin) with cold water cooling of the pancreas opening during an endoscopic procedure can better prevent pancreatitis—a painful inflammation of the pancreas—compared to medication alone.
Hyderabad, TelanganaAges 18–60 - NCT07579312Recruiting
Blood Test for Diagnosing Belly Infections in Kids and Adults
This study tests whether a simple blood test measuring RNA levels can help doctors quickly identify intra-abdominal infections (infections inside the belly) in patients with abdominal pain. If successful, it could help doctors decide faster whether imaging or surgery is needed.
Washington D.C., District of ColumbiaAges 7 years+ - NCT07579780Recruiting
Nerve Block During Laparoscopic Colorectal Cancer Surgery
This trial tests a pain-relief technique called a nerve block during minimally invasive surgery to remove colorectal cancer. The block numbs nerves in the lower abdomen to potentially reduce pain and improve recovery after surgery.
Guangzhou, GuangdongAges 18 years+ - NCT07581756Recruiting
Brain Stimulation Treatment for Diarrhea-Prone Irritable Bowel Syndrome
This trial tests whether repeated magnetic stimulation applied to the scalp (a non-invasive procedure) can reduce diarrhea and belly pain in people with diarrhea-predominant IBS. The goal is to see if this brain-based treatment can improve your symptoms.
Suzhou, JiangsuAges 18–70 - NCT07581912RecruitingPhase 2
Fulzerasib Plus Cetuximab for Advanced Colorectal Cancer With KRAS G12C
This trial tests a combination of two drugs (fulzerasib and cetuximab) given before surgery to shrink locally advanced colorectal cancer that has a specific genetic mutation called KRAS G12C. The goal is to help make the cancer easier to remove surgically and improve outcomes.
Hangzhou, ZhejiangAges 18–85 - NCT07581977Recruiting
A Clip Tool for Removing Small Stomach Growths
This trial tests a new two-tooth clip device designed to help doctors safely remove small gastrointestinal tumors (GISTs) from the stomach using endoscopy—a thin camera inserted through the mouth. The clip may make the removal procedure easier and safer.
BeijingAges 18–85 - NCT07584278Recruiting
Probiotics and Biomarkers for Irritable Bowel Syndrome
This study tests whether probiotics (beneficial bacteria) can help reduce irritable bowel syndrome (IBS) symptoms and change certain markers in your gut. You'll take a probiotic supplement for 12 weeks while researchers track how your symptoms and gut health change.
GothenburgAges 18 years+ - NCT07584473Recruiting
Testing for Non-Celiac Wheat Sensitivity in Celiac Disease Relatives
This study investigates whether relatives of celiac disease patients who have digestive symptoms and other health concerns might have non-celiac wheat sensitivity or irritable bowel syndrome. Researchers will perform a small intestinal biopsy and dietary testing to understand the connection between wheat sensitivity and symptoms in this family group.
Palermo, PAAges 18 years+ - NCT07584577Recruiting
Nutrition Support During Cancer Treatment Before Surgery
This study tests whether a special feeding tube placed in the small intestine helps patients recover better after surgery for esophageal or stomach cancer. The tube delivers nutrition directly during chemotherapy or radiation before surgery.
PessacAges 18 years+ - NCT07585032Recruiting
Ultrasound-guided heat treatment for pancreatic insulinoma tumors
This trial tests a minimally invasive procedure that uses heat (delivered through an ultrasound scope) to treat insulinoma—a hormone-producing pancreatic tumor that causes low blood sugar. The procedure may offer a less invasive alternative to surgery.
GothenburgAges 15–80 - NCT07585214Recruiting
Screening for lung and heart disease using chest X-rays
This study uses chest X-rays to screen for early signs of lung and heart disease in people without known serious disease. Researchers want to understand how well routine chest imaging can catch health problems early.
Dazhou, SichuanAges 18 years+ - NCT07585669Recruiting
Omega-3 Supplements for New Celiac Disease Patients
This study tests whether omega-3 fatty acids (a type of fish oil supplement) can reduce inflammation and improve gut health in people newly diagnosed with celiac disease. Participants will follow a gluten-free diet while taking the supplement to see if it helps their body heal.
Santiago, Metropolitan RegionAges 18–65 - NCT07586384Recruiting
Single-Port vs Standard Laparoscopic Surgery for Stomach Cancer
This trial compares two minimally invasive surgical approaches for early-stage stomach cancer affecting the upper portion. Researchers want to see if a newer single-port technique (using one small incision) works as well as traditional laparoscopic surgery (using multiple small incisions) and may cause less pain or faster recovery.
Wenzhou, ZhejiangAges 18–80 - NCT07586813RecruitingPhase 2
Romiplostim N01 Plus ATRA for Low Platelets After Gut Cancer
This trial tests a combination of two medicines (Romiplostim N01 and ATRA) to raise dangerously low platelet counts that sometimes persist after chemotherapy for digestive cancers. If your platelets stay low even after previous platelet-raising treatments, this study may help.
BeijingAges 18 years+ - NCT07587216Recruiting
Liver Cancer Patient Database Study
This study builds a database of information from liver cancer patients treated at Tongji Hospital. Researchers will collect your medical records and treatment information to better understand liver cancer diagnosis and care over time.
Wuhan, HubeiAges 18 years+ - NCT07587229Recruiting
Predicting chemotherapy response in gastric cancer
This research study analyzes tumor tissue samples to understand why some patients respond better to chemotherapy after gastric cancer surgery. By studying how genes are processed in cancer cells, researchers hope to predict which patients will benefit most from treatment.
Duarte, CaliforniaAges 18 years+
Common questions
- How many digestive system clinical trials are recruiting?
- Clin2 is tracking 7,916 recruiting gastroenterology studies from the U.S. registry right now, out of 12,516 we cover in this area in total.
- What does “Digestive system” cover here?
- Conditions of the stomach, intestines, liver, and the rest of the digestive tract. We group each study into digestive system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a digestive system trial near me?
- Use the search to filter digestive system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.