Gastroenterology
Digestive system clinical trials
Conditions of the stomach, intestines, liver, and the rest of the digestive tract. We’re tracking 7,606 recruiting studies in this area right now.
By phase
- Not applicable4,685
- Phase 21,189
- Phase 1568
- Phase 3457
- Phase 1/Phase 2368
- Phase 4229
- Phase 2/Phase 3110
Top conditions
- Colorectal Cancer479
- Pancreatic Cancer287
- Gastric Cancer283
- Hepatocellular Carcinoma256
- Esophageal Cancer189
- Rectal Cancer168
- Breast Cancer146
- Crohn Disease134
- Ulcerative Colitis129
- Colon Cancer114
- Hepatocellular Carcinoma (HCC)112
- Liver Cancer99
- Lung Cancer95
- Inflammatory Bowel Diseases94
- Pancreas Cancer90
- Ovarian Cancer89
- Esophageal Squamous Cell Carcinoma86
- Cystic Fibrosis77
Leading sponsors
- Fudan University100
- Sun Yat-sen University85
- Mayo Clinic75
- Second Affiliated Hospital, Zhejiang University, School of Medicine56
- Chinese University of Hong Kong55
- M.D. Anderson Cancer Center55
- Assistance Publique - Hôpitaux de Paris53
- Sixth Affiliated Hospital, Sun Yat-sen University51
- National Cancer Institute (NCI)50
- National Taiwan University Hospital45
Where studies are running
- California442
- Arizona190
- Texas140
- Alabama129
- Florida127
- New York120
- Massachusetts119
- Maryland88
- Ohio80
- Illinois69
Recruiting studies7,606 total
- NCT07716189RecruitingPhase 3
Ear Acupuncture plus Dexamethasone for Nausea from Trastuzumab Deruxtecan
This trial tests if adding ear acupuncture to a standard anti-nausea medicine (dexamethasone) works better for nausea and vomiting caused by the breast cancer drug trastuzumab deruxtecan. The goal is to help you feel better during treatment.
HangzhouAges 18–85 - NCT07717554Recruiting
Virtual yoga for diabetic stomach-pain relief
This study tests if virtual yoga classes can help people with diabetes and gastroparesis (slow stomach emptying) feel better. It looks at whether yoga can ease symptoms like nausea, bloating, and stomach pain.
Columbus, OhioAges 18–65 - NCT07715500Recruiting
MRI of Bile Ducts in Living Liver Donors
This study uses an MRI scan to look at the bile ducts in healthy people who want to donate part of their liver. The goal is to see if the scan can help predict and prevent bile duct problems for the person receiving the liver.
New DelhiAges 18–55 - NCT05719246Recruiting
Yoga and meditation for teens with IBS stress
This study tests a structured yoga and meditation program to help reduce stress symptoms in teens with irritable bowel syndrome (IBS). It may help your teen learn calming practices that could ease how stress affects IBS.
Camden, New JerseyAges 12–21 - NCT05462496RecruitingPhase 2
Pembrolizumab plus gut microbiome changes after pancreatic chemo
This Phase 2 study tests whether changing the gut microbiome (the gut’s helpful bacteria) and giving pembrolizumab after chemotherapy can improve outcomes for people with operable pancreatic cancer. It aims to see if this approach can boost the immune system after standard treatment and help reduce cancer returning.
New York, New YorkAges 19 years+ - NCT05508126Recruiting
MRI and special CT scans to study stomach cancer
This trial studies how two types of scans—multi-parameter MRI and special CT (dual-energy CT)—look in people with confirmed stomach cancer before surgery. It may help doctors better understand the cancer and improve planning based on scan features.
NanjingAges 18 years+ - NCT05894746Recruiting
Study to improve blood sugar and reduce inflammation
This study looks at how an intervention may improve blood sugar control and lower inflammation in the body. You may be able to take part unless you have a specific condition called celiac disease.
GothenburgAges 6 years+ - NCT06211868Recruiting
Early heart disease risk study for adults 40-70
This study looks at whether changing your immune system, fats, and metabolism can lower your risk of early heart disease. It is for people with an intermediate to high risk score but who have not yet had a heart attack or stroke.
SingaporeAges 40–70 - NCT06039696Recruiting
Testing a new way to find infections in liver disease patients
This trial uses a DNA test to better detect infections in people with advanced liver disease who are hospitalized. It may help doctors find the right treatment faster.
Guangzhou, GuangdongAges 18–80 - NCT06395935Recruiting
Wellness care study for gastric cancer survivors
This study tests a wellness program for people who had surgery for gastric cancer (stomach cancer). It aims to help survivors recover better after their operation.
Changwon, Gyeongsandnam-doAges 19–75 - NCT06602011Recruiting
Triple therapy for advanced liver cancer with bile duct invasion
This study tests a combination of three treatments—TACE (a procedure that blocks blood flow to the tumor), lenvatinib (a targeted therapy pill), and tislelizumab (an immunotherapy)—for people with liver cancer that has spread into the bile ducts and can't be removed by surgery. The goal is to see if this triple therapy helps shrink or control the cancer.
Fuzhou, FujianAges 18–75 - NCT06621277Recruiting
Improving care for young adults with GI cancer
This study aims to improve care for younger adults (ages 18-50) with gastrointestinal (GI) tumors. Researchers will test ways to better support patients during and after treatment. If you are 18-50 and being treated for a GI tumor at Heidelberg University Hospital, you may be able to join.
Heidelberg, Baden-WurttembergAges 18 years+ - NCT07713810Recruiting
Can supplements help with constipation? A study on health products
This study tests if certain health and wellness products can improve constipation and related health issues. It compares the active product to a placebo (a dummy product without active ingredients) to see if it really works.
Del Mar, CaliforniaAges 21–105 - NCT07713485RecruitingPhase 1
XmAb412 study in healthy adults
This is a first-in-human study testing a new drug called XmAb412 in healthy volunteers. It helps researchers understand how the drug works in the body and if it's safe.
Joondalup, Western AustraliaAges 18–55 - NCT07710885RecruitingPhase 3
Futibatinib for advanced bile duct cancer
This trial tests a new targeted therapy, futibatinib, for people with advanced or unresectable bile duct cancer who have not had prior treatment for advanced disease. It aims to see if this drug can help shrink or control the cancer.
BrisbaneAges 18 years+ - NCT07709520RecruitingPhase 2
Testing a new hepatitis B treatment in adults
This trial tests a new treatment (GST-HG131&141 tablets) versus a placebo for people with chronic hepatitis B. It aims to see if the treatment can better control the virus in those already on stable therapy.
BeijingAges 35–65 - NCT07709897RecruitingPhase 2
Preventing nausea & vomiting after surgery
This trial tests if adding HRS5580 to standard anti-nausea medicine works better to stop vomiting after surgery. You may qualify if you are at moderate-to-high risk for nausea after general anesthesia.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT07714499Recruiting
Energy use in healthy people vs. those with intestinal failure
This study looks at how the body uses energy (calories) in people with intestinal failure compared to healthy controls. The results may help improve nutritional care.
LjubljanaAges 18–65 - NCT07714278Enrolling by invitation
Video-based rehab for chemotherapy nerve damage
This study tests a personalized rehab program using video analysis to help people with chemotherapy-induced nerve damage (numbness, tingling, weakness) improve their walking and daily life.
Seongnam-si, Gyeonggi-doAges 19 years+ - NCT07711912Enrolling by invitation
Polish AntiReflux Study (POLAR)
This study looks at how well acid reflux surgery works for people with GERD (chronic heartburn). If you're already scheduled for this surgery at a participating hospital, you may be able to join.
Olsztyn, Warminsko-mazusrkieAges 18 years+ - NCT07708467Enrolling by invitation
Esophageal function study in eosinophilic esophagitis
This study looks at how the esophagus stretches and moves in people with eosinophilic esophagitis (EoE) who still have symptoms even though their inflammation is under control. The goal is to better understand why symptoms persist and find better ways to measure them.
Milan, MIAges 18 years+ - NCT07708220Recruiting
Laparoscopic treatment for acid reflux in children
This trial tests a minimally invasive surgery to treat gastroesophageal reflux disease (GERD) in children. It aims to reduce symptoms and improve quality of life for kids who have not had prior reflux surgery.
TantaAges 2–18 - NCT07708545RecruitingPhase 2
Comparing two drugs for bleeding ulcers
This trial tests whether a newer drug, tegoprazan, works as well as the standard drug lansoprazole for healing bleeding ulcers in the stomach or small intestine. You will get one of these drugs for 14 days and have a follow-up endoscopy to check healing.
Tangerang, BantenAges 18 years+ - NCT07714850Recruiting
Endoscopy in acute pancreatitis study
This study looks at whether an upper endoscopy (a camera test to look inside your stomach and the first part of your small intestine) done within 24-48 hours of being admitted to the hospital can help guide treatment for acute pancreatitis. You may be able to join if you are an adult with a confirmed case of acute pancreatitis and are able to safely undergo this procedure.
KielceAges 18 years+
Common questions
- How many digestive system clinical trials are recruiting?
- Clin2 is tracking 7,606 recruiting gastroenterology studies from the U.S. registry right now, out of 11,952 we cover in this area in total.
- What does “Digestive system” cover here?
- Conditions of the stomach, intestines, liver, and the rest of the digestive tract. We group each study into digestive system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a digestive system trial near me?
- Use the search to filter digestive system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.