Otolaryngology
Ear, nose & throat clinical trials
Hearing, balance, and conditions of the ears, nose, sinuses, and throat. We’re tracking 1,269 recruiting studies in this area right now.
By phase
- Not applicable890
- Phase 2154
- Phase 3103
- Phase 147
- Phase 431
- Phase 1/Phase 230
- Phase 2/Phase 314
Top conditions
- Nasopharyngeal Carcinoma73
- Dysphagia66
- Hearing Loss61
- Tinnitus29
- Hearing Loss, Sensorineural24
- Nasopharyngeal Carcinoma (NPC)24
- Head and Neck Cancer23
- Allergic Rhinitis22
- Oropharynx Cancer21
- Nasopharyngeal Cancinoma (NPC)18
- Sensorineural Hearing Loss18
- Stroke17
- Oropharyngeal Cancer14
- Vestibular Schwannoma14
- Chronic Rhinosinusitis With Nasal Polyps13
- Deafness13
- Head and Neck Squamous Cell Carcinoma13
- Nasopharyngeal Cancer13
Leading sponsors
- Sun Yat-sen University57
- Assistance Publique - Hôpitaux de Paris14
- Eye & ENT Hospital of Fudan University14
- National Cancer Institute (NCI)14
- Cairo University13
- NYU Langone Health13
- Mayo Clinic12
- Johns Hopkins University11
- Ming-Yuan Chen11
- Massachusetts Eye and Ear Infirmary10
Where studies are running
- California61
- Maryland38
- Florida32
- New York32
- Massachusetts24
- Illinois20
- Texas20
- Alabama15
- Arizona15
- Colorado15
Recruiting studies1,269 total
- NCT07468864Recruiting
Turkish vertigo questionnaire study
This study tests a questionnaire for people who feel dizzy in certain visual or busy environments. It helps researchers see if the Turkish version of the test works well.
Bağcılar, GüneşliAges 18 years+ - NCT04544969Recruiting
Testing blood markers to guide chemo for metastatic nasopharyngeal cancer
This study looks at special blood markers (CTCs) to see how sensitive your cancer is to chemotherapy and to better predict how well treatment may work. If you have metastatic nasopharyngeal cancer and can’t have local treatment, this may help match you to more effective chemo plans.
Guangzhou, GuangdongAges 18–70 - NCT05331170RecruitingPhase 2
Re-training the nose to change how allergies behave
This Phase 2 study tests a “viral” treatment meant to reprogram the lining of your nose to reduce allergy-like immune responses. It is testing whether this approach is safe and can help people with cat allergy (with or without asthma) or compare against healthy people.
Galveston, TexasAges 18–60 - NCT07461467Recruiting
Managing breathing tube pressure to reduce throat problems in older adults
This study tests a way of managing the air pressure in a breathing tube mask used during surgery. The goal is to reduce throat and voice box problems after surgery in older patients.
Chongqing, Chongqing MunicipalityAges 60 years+ - NCT07459296RecruitingPhase 3
Becotatug vedotin plus sintilimab for advanced nasopharyngeal cancer
This trial tests a combination of two drugs, becotatug vedotin and sintilimab, for patients with a type of nasopharyngeal cancer that has spread to nearby lymph nodes but not to distant organs. It aims to see if this treatment can help control the disease.
Nanning, GuangxiAges 18–70 - NCT07457346RecruitingPhase 2
Testing emactinib with chemo and immunotherapy before head and neck cancer surgery
This trial tests whether combining the drug emactinib with chemotherapy and immunotherapy before surgery helps treat advanced head and neck cancer. It aims to shrink tumors and make surgery more effective.
Hangzhou, ZhejiangAges 18–75 - NCT06796270Recruiting
Short-course radiation for nasopharyngeal cancer
This trial tests a shorter course of radiation therapy for people with nasopharyngeal cancer, a type of head and neck cancer. The goal is to see if a hypofractionated (fewer, larger doses) approach is safe and effective.
Haikou, HainanAges 18–75 - NCT06725732RecruitingEarly Phase 1
Nebulized tranexamic acid for reducing bleeding during sinus surgery
This early-phase study tests if giving tranexamic acid (a medicine that helps blood clot) through a mist into the nose and sinuses during sinus surgery can reduce bleeding. It is designed for adults who are otherwise healthy and undergoing a common type of sinus surgery called functional endoscopic sinus surgery (FESS).
AsyutAges 18–65 - NCT05287022Recruiting
Nasal nitric oxide test to improve primary ciliary dyskinesia care
This study tests whether a breathing test called nasal nitric oxide can help improve care for people with primary ciliary dyskinesia (PCD) or related lung/sinus problems. The goal is to see if the test can better guide diagnosis and treatment planning.
Little Rock, ArkansasAges 2–99 - NCT06801522RecruitingPhase 2/Phase 3
Nasal spray comparison during breathing tube placement
This trial compares two nasal medications (adrenaline and xylometazoline) to see which one reduces bleeding better when placing a breathing tube through the nose. It may help people undergoing planned mouth or jaw surgery.
Karachi, SindhAges 18–60 - NCT07447427Recruiting
Language development in kids with cochlear implants and speech therapy
This study looks at how children with cochlear implants develop language and how speech-language therapy can help. It may be a good fit for children who received a cochlear implant between 8 and 24 months old and have had follow-up care for at least two years.
Paris, Île-de-France RegionAges 2.7 years–4 years - NCT07451028Recruiting
Mouth training device for swallowing problems after stroke
This trial tests a device that strengthens mouth muscles to help people who have trouble swallowing after their first stroke. It may improve your ability to swallow safely.
Hammel, JutlandAges 18 years+ - NCT07449949Enrolling by invitation
Sequential chemoradiation and surgery for nasal rhabdomyosarcoma
This trial tests a treatment plan of chemotherapy, radiation, and then surgery for adults with rhabdomyosarcoma in the nose or sinus cavities. It aims to see if this sequence helps control the cancer.
Shanghai, ChinaAges 18–70 - NCT07452380Recruiting
Dust mite allergy shot therapy for kids with rhinitis or asthma
This trial tests allergy shots for children with dust mite allergies causing rhinitis or asthma. It aims to see if guiding treatment with detailed allergy testing leads to better results.
Hangzhou, ZhejiangAges 5–18 - NCT07445204Enrolling by invitation
Electrical stimulation for swallowing after stroke
This trial tests whether a gentle electrical stimulation technique on neck muscles can help improve swallowing in people who recently had a stroke. It may be a good option if you are still having trouble swallowing after your stroke.
IstanbulAges 18 years+ - NCT06803095Recruiting
Walking with a dog for tinnitus relief in sleep apnea
This study tests whether walking with a dog can help reduce tinnitus complaints in people who have mild sleep apnea and are overweight. It aims to see if this simple, enjoyable activity can improve your symptoms.
Dokki, Giza GovernorateAges 30–45 - NCT07436949RecruitingPhase 1/Phase 2
Study of BBT002 for chronic sinusitis with nasal polyps and asthma
This study tests a new drug called BBT002 in healthy people and in patients with chronic sinusitis and nasal polyps, with or without asthma. It aims to see if the drug is safe and effective for reducing symptoms.
Beijing, Beijing MunicipalityAges 18–75 - NCT07441681RecruitingPhase 3
Comparing radiation plus targeted therapy vs standard chemo for head and neck cancer
This trial compares two treatments for advanced head and neck cancer in patients who cannot take the drug cisplatin. One group gets radiation plus a targeted drug called cetuximab, the other gets radiation plus standard chemotherapy. The goal is to see which approach works better and is safer for people who are not candidates for cisplatin.
Beverly Hills, CaliforniaAges 18 years+ - NCT07435155Recruiting
Voice and breathing test for speech problems after brain injury
This study uses voice recordings and breathing tests to better understand speech problems (dysarthria) that can happen after a brain injury. It may help improve how these problems are diagnosed and treated.
Salamanca, SalamancaAges 18 years+ - NCT07444528Enrolling by invitation
Neck ultrasound to predict difficult breathing tube placement in babies
This study uses an ultrasound of the neck to see if doctors can predict which babies under 1 year old might have a harder time getting a breathing tube placed. The goal is to improve safety during anesthesia and procedures.
Philadelphia, PennsylvaniaAges Up to 12 months - NCT07440290RecruitingPhase 2/Phase 3
Dabrafenib and trametinib for BRAF V600 cancers
This trial tests two targeted drugs (dabrafenib and trametinib) for patients whose cancer has a specific change in the BRAF gene called V600. These drugs work together to block signals that help the cancer grow. The trial is for children, teenagers, and adults with many types of cancer, except for a few common ones that already have approved treatments.
BelfastAges 1 year+ - NCT07443891Recruiting
Brain changes from vibration in laryngeal dystonia
This study uses a gentle vibrating device placed on the skin to see how it affects brain activity in people with laryngeal dystonia (a voice disorder). The goal is to learn more about how the brain controls voice and maybe find new ways to help.
Minneapolis, MinnesotaAges 18–75 - NCT07435714Recruiting
Helping patients choose surgery for chronic nasal swelling
This trial is testing a tool called a patient decision aid to help people with chronic hypertrophic rhinitis (long-term nasal swelling) make better choices about their surgery. You will be asked to use the aid and share your thoughts.
New Taipei CityAges 18 years+ - NCT05119842Recruiting
Implant study for permanent voice weakness from vocal cord closure
This study tests a voice implant device in people with permanent vocal cord weakness (UVFP) who have trouble closing their vocal cords. It aims to improve voice strength and reduce voice-related burden, while checking safety over the study period.
Phoenix, ArizonaAges 18–80
Common questions
- How many ear, nose & throat clinical trials are recruiting?
- Clin2 is tracking 1,269 recruiting otolaryngology studies from the U.S. registry right now, out of 2,074 we cover in this area in total.
- What does “Ear, nose & throat” cover here?
- Hearing, balance, and conditions of the ears, nose, sinuses, and throat. We group each study into ear, nose & throat based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a ear, nose & throat trial near me?
- Use the search to filter ear, nose & throat studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.