Otolaryngology
Ear, nose & throat clinical trials
Hearing, balance, and conditions of the ears, nose, sinuses, and throat. We’re tracking 1,269 recruiting studies in this area right now.
By phase
- Not applicable890
- Phase 2154
- Phase 3103
- Phase 147
- Phase 431
- Phase 1/Phase 230
- Phase 2/Phase 314
Top conditions
- Nasopharyngeal Carcinoma73
- Dysphagia66
- Hearing Loss61
- Tinnitus29
- Hearing Loss, Sensorineural24
- Nasopharyngeal Carcinoma (NPC)24
- Head and Neck Cancer23
- Allergic Rhinitis22
- Oropharynx Cancer21
- Nasopharyngeal Cancinoma (NPC)18
- Sensorineural Hearing Loss18
- Stroke17
- Oropharyngeal Cancer14
- Vestibular Schwannoma14
- Chronic Rhinosinusitis With Nasal Polyps13
- Deafness13
- Head and Neck Squamous Cell Carcinoma13
- Nasopharyngeal Cancer13
Leading sponsors
- Sun Yat-sen University57
- Assistance Publique - Hôpitaux de Paris14
- Eye & ENT Hospital of Fudan University14
- National Cancer Institute (NCI)14
- Cairo University13
- NYU Langone Health13
- Mayo Clinic12
- Johns Hopkins University11
- Ming-Yuan Chen11
- Massachusetts Eye and Ear Infirmary10
Where studies are running
- California61
- Maryland38
- Florida32
- New York32
- Massachusetts24
- Illinois20
- Texas20
- Alabama15
- Arizona15
- Colorado15
Recruiting studies1,269 total
- NCT07431125Recruiting
Surgery and hearing test link in one-sided conductive hearing loss
This study looks at how surgery findings relate to hearing tests in people with one-sided conductive hearing loss but a normal eardrum. It may help if you have a specific type of hearing loss where sound is blocked, and your eardrum is intact.
Asyut, Asyut GovernorateAges Any age - NCT07426835Recruiting
Comparing two hernia prevention methods in robotic esophageal cancer surgery
This trial compares two ways of closing the diaphragm during robotic esophageal cancer surgery to see if one reduces the chance of a hernia later. If you're having a robotic esophagectomy for cure, you may be able to join.
Dublin, BeaumontAges 18 years+ - NCT07434583Recruiting
Force sensor study for laryngeal surgery patients
This trial tests a force sensor tool used during laryngeal surgery (surgery on the voice box) via direct laryngoscopy (a tube inserted through the mouth). It may help surgeons apply the right amount of force to reduce tongue injuries.
San Francisco, CaliforniaAges 18 years+ - NCT06767696Recruiting
Neck position and breathing tube pressure in children
This study checks if tilting a child's head back during surgery changes the pressure in the breathing tube. It helps doctors make sure children's airways stay safe during tonsil or adenoid removal.
Ankara, KeçiörenAges 2–18 - NCT06275269Recruiting
Comparing two ways to inject steroids for throat narrowing
This trial tests two methods of injecting triamcinolone (a steroid) into the narrowed part of the throat (subglottic stenosis) to see which works better: one guided by a camera during an endoscopy, the other guided by ultrasound. It may help people who have trouble breathing or a hoarse voice due to this condition.
Beijing, Beijing MunicipalityAges 18–65 - NCT06814457Recruiting
Nursing care bundle for swallowing after breathing tube removal in children
This trial tests a special nursing care plan to help children who had a breathing tube eat and drink safely after it's removed. It aims to reduce swallowing problems in the intensive care unit.
Kafr ash Shaykh, Kafr Ash Shaykh, Kafr el-Sheikh, Egypt,Ages 6–18 - NCT07419464RecruitingPhase 2
Testing 5-FU for head and neck cancer that has returned
This trial tests the drug 5-fluorouracil (5-FU) in people with head and neck cancer that has come back or spread. It aims to see if 5-FU can help when other treatments have stopped working.
St Louis, MissouriAges 18 years+ - NCT07420803Recruiting
Nerve stimulation study for chronic dizziness
This study tests if a gentle, non-invasive nerve stimulation in the ear can help reduce chronic dizziness. It is for people with a specific type of dizziness called PPPD that has lasted at least 3 months.
Jacksonville, FloridaAges 18 years+ - NCT07419230Recruiting
Digital tool to help with allergy shot adherence
This trial tests a digital tool designed to help patients stick to their allergy immunotherapy schedule. If you have allergic rhinitis (with or without asthma) and are starting a new single-allergy treatment, you may be able to join.
Madrid, MadridAges Any age - NCT07417956Recruiting
Measuring reflex in cochlear implant for kids
This study tests a new way to program cochlear implants in children by measuring a tiny muscle reflex in the ear. This could help doctors set the sound levels more accurately without needing the child to respond.
Paris, Île-de-France RegionAges birth–7 years - NCT07420530RecruitingPhase 2
Exercise and breathing study for young adults with vocal cord issues
This study looks at how the vocal cords move during exercise in young adults who have trouble breathing while active. It may help researchers understand why this happens and how to better diagnose and treat it.
Bloomington, IndianaAges 18–26 - NCT07417267Enrolling by invitation
Clean Air Study for Lung Health in CF or PCD
This study tests whether using air cleaners in your home can improve lung health for people with cystic fibrosis (CF) or primary ciliary dyskinesia (PCD). It takes place in Cyprus and requires you to stay at home most days.
Nicosia, AglantziaAges 6 years+ - NCT05679271Recruiting
Stent treatment for low-grade dural AV fistula causing ringing
This trial tests whether placing a small tube (stent) inside a brain vein-sinus can reduce a pulsating ringing sound caused by a “dural arteriovenous fistula” (DAVF). It’s for people whose tinnitus matches the DAVF location and who meet imaging and medication safety requirements.
BordeauxAges 18 years+ - NCT06470217RecruitingPhase 2
Study of tirilizumab plus chemo for advanced oral cancer
This trial tests a combination of immunotherapy (tirilizumab) and two chemotherapy drugs (albumin-bound paclitaxel and cisplatin) for people with advanced but removable oral cancer. The goal is to see if this treatment shrinks the tumor before surgery and improves outcomes.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT07407582RecruitingPhase 1/Phase 2
Sodium thiosulfate to protect hearing during cisplatin chemo
This trial tests whether a medicine called sodium thiosulfate can protect your hearing from the side effects of cisplatin chemotherapy. It is for people with newly diagnosed cancer who are about to receive cisplatin for the first time.
Tucson, ArizonaAges 18 years+ - NCT07412314Recruiting
Proton Therapy for Recurrent Nasopharyngeal Cancer
This trial uses proton therapy (a precise type of radiation) to treat people whose nasopharyngeal cancer has come back. It aims to see if this treatment can help control the cancer while limiting side effects.
Guangzhou, GuangdongAges 18 years+ - NCT07411092Recruiting
3D-printed expander vs. traditional expander for widening the upper jaw in teens
This trial compares a new 3D-printed expander with a standard one to widen the upper jaw in teenagers. It aims to see if the newer device works better or is easier to tolerate.
Cairo, Cairo GovernorateAges 12–17 - NCT07416292Recruiting
Hearing and hard-of-hearing teen study
This study looks at how hearing loss affects teenagers' language and thinking skills. It compares teens with hearing loss to those with typical hearing to better understand listening and development.
HelsinkiAges 11–16 - NCT04670172Recruiting
Chronic sinusitis patient registry using a phone app
This study builds a real-world record of symptoms and outcomes in people with chronic sinusitis. You may help by using a smartphone app to report your symptoms over time.
GrazAges 18 years+ - NCT05115968Recruiting
Study tonsil cell changes in children with sleep apnea
This study uses a lab method called single-cell sequencing to look at tiny cells from tonsil tissue in children. It compares children with obstructive sleep apnea to children without it, to better understand what’s happening in the throat and how it may relate to needing tonsil removal.
Hong KongAges 6–11 - NCT07398859RecruitingPhase 2
New injection for seasonal allergy symptoms
This study tests an investigational injection called TQH2722 combined with standard allergy therapy for seasonal allergic rhinitis (hay fever). It may help people whose allergy symptoms are not well controlled during pollen season.
Beijing, Beijing MunicipalityAges 18–75 - NCT07402941Recruiting
Testing inner ear stimulation during awake ear surgery
This study tests a new way to stimulate your hearing nerve during ear surgery while you are awake. It might help doctors better understand hearing loss and improve future treatments.
Cleveland, OhioAges 18 years+ - NCT07401732Recruiting
Dysphagia in rheumatoid arthritis study
This study looks at swallowing problems (dysphagia) in people with rheumatoid arthritis to understand how common they are and what might cause them. It uses a flexible scope through the nose to examine swallowing function.
Tanta, ElgharbiaAges 18 years+ - NCT06827301Recruiting
Vagus nerve stimulation for swallowing problems after stroke
This trial tests a non-invasive device that stimulates a nerve in the ear to help improve swallowing after a recent stroke. It may be an option if you have moderate swallowing difficulties diagnosed within the first week after your stroke.
Roma, RMAges 18 years+
Common questions
- How many ear, nose & throat clinical trials are recruiting?
- Clin2 is tracking 1,269 recruiting otolaryngology studies from the U.S. registry right now, out of 2,074 we cover in this area in total.
- What does “Ear, nose & throat” cover here?
- Hearing, balance, and conditions of the ears, nose, sinuses, and throat. We group each study into ear, nose & throat based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a ear, nose & throat trial near me?
- Use the search to filter ear, nose & throat studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.