Otolaryngology
Ear, nose & throat clinical trials
Hearing, balance, and conditions of the ears, nose, sinuses, and throat. We’re tracking 1,366 recruiting studies in this area right now.
By phase
- Not applicable975
- Phase 2167
- Phase 398
- Phase 146
- Phase 434
- Phase 1/Phase 232
- Phase 2/Phase 314
Top conditions
- Nasopharyngeal Carcinoma80
- Dysphagia72
- Hearing Loss61
- Tinnitus31
- Hearing Loss, Sensorineural25
- Allergic Rhinitis23
- Nasopharyngeal Carcinoma (NPC)23
- Head and Neck Cancer22
- Oropharynx Cancer21
- Stroke19
- Sensorineural Hearing Loss18
- Nasopharyngeal Cancinoma (NPC)16
- Chronic Rhinosinusitis With Nasal Polyps15
- Oropharyngeal Cancer15
- Nasopharyngeal Cancer14
- Vestibular Schwannoma14
- Head and Neck Squamous Cell Carcinoma13
- Chronic Rhinosinusitis (CRS)12
Leading sponsors
- Sun Yat-sen University58
- Eye & ENT Hospital of Fudan University17
- Cairo University15
- Assistance Publique - Hôpitaux de Paris14
- NYU Langone Health14
- Mayo Clinic12
- National Cancer Institute (NCI)12
- Johns Hopkins University11
- Ming-Yuan Chen10
- Cochlear9
Where studies are running
- California62
- Maryland37
- New York35
- Florida29
- Massachusetts21
- Illinois20
- Arizona17
- Texas17
- Colorado16
- Alabama15
Recruiting studies1,366 total
- NCT03439865RecruitingEarly Phase 1
Ivacaftor for sinus problems linked to faulty CFTR
This early-phase study tests whether ivacaftor can improve chronic sinus disease caused by problems with a specific body channel called CFTR. It may help some people whose sinus imaging, cultures, and prior sinus surgery match the study’s criteria.
Birmingham, AlabamaAges 18 years+ - NCT03707691Recruiting
Test training for pitch perception and memory abilities
This study looks at how people perceive musical pitch and how that relates to memory, and whether training can improve performance. It may help researchers learn why some people struggle with pitch-related tasks and what kinds of training work best.
BronAges 5–90 - NCT06552676Recruiting
Risk factors for neck infection after tracheostomy in ICU
This study looks at why some patients in the ICU get a serious neck infection after a tracheostomy. It only includes patients who get a tracheostomy through the skin, not through surgery.
BolognaAges 18 years+ - NCT06767696Recruiting
Neck position and breathing tube pressure in children
This study checks if tilting a child's head back during surgery changes the pressure in the breathing tube. It helps doctors make sure children's airways stay safe during tonsil or adenoid removal.
Ankara, KeçiörenAges 2–18 - NCT06734897Recruiting
Music therapy for better hearing with cochlear implants
This study tests whether music therapy can help people with cochlear implants understand speech better in noisy environments. If you are getting a new cochlear implant and speak German, you may be able to join.
Lucerne, Canton of LucerneAges 18–85 - NCT06734975RecruitingPhase 2
Nerve block for better recovery after vocal cord surgery
This study tests if a nerve block can help reduce pain and improve recovery after surgery to remove a noncancerous growth on the vocal cords. Participants will be randomly assigned to receive either the nerve block or standard care.
Newark, New JerseyAges 18 years+ - NCT06726551Recruiting
AI to recognize key structures in ear surgery
This study uses artificial intelligence to analyze videos from ear surgeries that were done under a microscope. It aims to help doctors better identify important structures during operations.
Guangzhou, GuangdongAges 6 months–100 years - NCT06704256Recruiting
Using neck muscle scans to predict frailty before ENT surgery
This study looks at neck CT scans to see if muscle size can help predict frailty in people having ear, nose, or throat surgery. It may help doctors better prepare for your recovery.
New York, New YorkAges 18 years+ - NCT06700772RecruitingPhase 1
Bone Growth After Sinus Lift for Missing Upper Teeth
This study tests a surgery to build up bone in the upper jaw where teeth are missing. It may help people who need more bone to get dental implants later.
Cairo, New CairoAges 20–50 - NCT05924087Recruiting
Treatment study for narrowing of the windpipe after tracheotomy
This trial tests an interventional treatment for narrowing of the windpipe (tracheal stenosis) that happened after a percutaneous (through-skin) tracheotomy. It may help improve breathing and reduce problems caused by the narrowing.
NiddaAges 18 years+ - NCT05460520Recruiting
Test a therapy for Mal de Débarquement Syndrome symptoms
This trial studies a “DevRobust” treatment to reduce symptoms of Mal de Débarquement Syndrome (a persistent feeling of rocking or motion after travel or a trip). It may help by improving how your balance system responds and reducing day-to-day symptoms.
New York, New YorkAges 18–78 - NCT06616792Enrolling by invitation
Sound wave steroid vs. laser acupuncture for chronic sinusitis
This study tests two treatments for chronic sinusitis: one uses sound waves to deliver a steroid (dexamethasone) through the skin, and the other uses laser acupuncture. It aims to see which works better for reducing symptoms like congestion, facial pain, and reduced sense of smell.
Dokki, Giza GovernorateAges 30–50 - NCT06606262Recruiting
Tonsil removal surgery: total vs partial for recurrent tonsillitis
This study compares two different surgeries for treating frequent tonsillitis (sore throats that come back often): removing the entire tonsils versus removing only part of them. It aims to see which approach works better and has fewer side effects.
AalborgAges 15 years+ - NCT07281508RecruitingPhase 3
Preventing hearing loss from cisplatin in head and neck cancer
This trial tests whether a gel placed in the ear can protect against hearing loss caused by high-dose cisplatin chemotherapy. It is for people with head and neck cancer who are scheduled to receive a certain amount of cisplatin.
Amsterdam, North HollandAges 18 years+ - NCT07735078Recruiting
Smart balance and thinking exercise for older adults
This study tests a smart digital tool that combines balance and thinking exercises to help older adults stay steady and prevent falls. If you are 55+ and can walk a short distance, you may be able to join.
Taipei, TaipeiAges 55 years+ - NCT05414032RecruitingPhase 2
Using leftover DNA signals to guide treatment after head and neck cancer
This Phase 2 trial tests a drug strategy for people with locally advanced head and neck cancer linked to HPV status. It looks at “molecular residual disease” by measuring tumor DNA in blood and uses early response and tumor test results to see who may benefit.
TorontoAges 18 years+ - NCT06563479RecruitingPhase 3
Personalized vs. standard radiation for HPV-positive throat cancer
This trial compares a personalized, shorter course of radiation therapy to the standard longer course for people with HPV-positive throat cancer. The goal is to see if personalized treatment is just as effective while reducing side effects.
Hartford, ConnecticutAges 18 years+ - NCT06951594Recruiting
Robotic vs. manual cochlear implant electrode insertion
This trial compares a robotic-assisted method to the standard manual method for inserting the electrode array during cochlear implant surgery. The goal is to see which approach leads to better hearing outcomes.
Iowa City, IowaAges 18–80 - NCT07664826Recruiting
Acupuncture for reducing gag reflex
This study tests whether acupuncture can help reduce the gag reflex. If you are a healthy adult between 20 and 35 and have never had acupuncture, you might be able to participate.
GreifswaldAges 20–40 - NCT06000527Recruiting
A French study on juvenile recurrent respiratory papillomatosis
This study is creating a national group of patients with juvenile recurrent respiratory papillomatosis, a condition causing wart-like growths in the airway. It aims to learn more about the disease and improve care.
ParisAges Any age - NCT06003660Recruiting
Taste and smell after stem cell transplant
This study looks at how the transplant affects your sense of taste, smell, and mouth sensation. It may help doctors better understand and manage these changes.
Oslo, OsloAges 30–70 - NCT06005324RecruitingPhase 1
Personalized treatment for advanced head and neck cancer
This trial tests a custom treatment plan for people with advanced head and neck cancer that is not caused by HPV. It combines radiation and chemotherapy with a targeted drug called cetuximab, adjusted based on your tumor's characteristics.
Chicago, IllinoisAges 18 years+ - NCT06567821RecruitingPhase 2/Phase 3
Using navigation to improve balloon sinus surgery accuracy
This trial tests whether using a navigation system during balloon sinus surgery makes the procedure more accurate for people with chronic sinusitis. It may help improve outcomes for those who have not had sinus surgery before.
Los Angeles, CaliforniaAges 18 years+ - NCT06507709Recruiting
Sinus lift study using a special bone graft putty
This study tests a new type of bone graft putty for people who need a sinus lift before getting dental implants. It may be an option if you have some existing bone and are generally healthy or have well-controlled diabetes.
San Antonio, TexasAges 18–85
Common questions
- How many ear, nose & throat clinical trials are recruiting?
- Clin2 is tracking 1,366 recruiting otolaryngology studies from the U.S. registry right now, out of 2,207 we cover in this area in total.
- What does “Ear, nose & throat” cover here?
- Hearing, balance, and conditions of the ears, nose, sinuses, and throat. We group each study into ear, nose & throat based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a ear, nose & throat trial near me?
- Use the search to filter ear, nose & throat studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.