Otolaryngology
Ear, nose & throat clinical trials
Hearing, balance, and conditions of the ears, nose, sinuses, and throat. We’re tracking 1,371 recruiting studies in this area right now.
By phase
- Not applicable978
- Phase 2168
- Phase 399
- Phase 146
- Phase 434
- Phase 1/Phase 232
- Phase 2/Phase 314
Top conditions
- Nasopharyngeal Carcinoma80
- Dysphagia73
- Hearing Loss61
- Tinnitus31
- Hearing Loss, Sensorineural25
- Nasopharyngeal Carcinoma (NPC)24
- Allergic Rhinitis23
- Head and Neck Cancer22
- Oropharynx Cancer21
- Stroke20
- Sensorineural Hearing Loss18
- Nasopharyngeal Cancinoma (NPC)17
- Chronic Rhinosinusitis With Nasal Polyps15
- Oropharyngeal Cancer15
- Nasopharyngeal Cancer14
- Vestibular Schwannoma14
- Head and Neck Squamous Cell Carcinoma13
- Chronic Rhinosinusitis (CRS)12
Leading sponsors
- Sun Yat-sen University59
- Eye & ENT Hospital of Fudan University17
- Cairo University15
- Assistance Publique - Hôpitaux de Paris14
- NYU Langone Health14
- Mayo Clinic12
- National Cancer Institute (NCI)12
- Johns Hopkins University11
- Ming-Yuan Chen11
- Cochlear9
Where studies are running
- California62
- Maryland37
- New York35
- Florida30
- Massachusetts21
- Illinois20
- Texas18
- Arizona17
- Colorado16
- Alabama15
Recruiting studies1,371 total
- NCT06846385RecruitingPhase 2/Phase 3
Testing a new shot for severe seasonal hay fever
This study tests a new injection called MG-K10 for people with moderate-to-severe seasonal hay fever that isn't well controlled by standard treatments like nasal sprays or antihistamines. The goal is to see if it can reduce your allergy symptoms over the pollen season.
Beijing, Beijing MunicipalityAges 18–75 - NCT06852638RecruitingPhase 2
PET imaging for kidney cancer, lymphoma, and NPC
This study tests a new way to detect tumors by using a special injection that makes cancer cells visible on a PET scan. It may help people with renal cancer (especially clear cell type), lymphoma, or nasopharyngeal cancer.
ShanghaiAges 18–80 - NCT06851247RecruitingPhase 2
Chemoradiation plus toripalimab for advanced nasopharyngeal cancer
This trial tests a new treatment for advanced nasopharyngeal cancer. You will get chemotherapy and radiation, followed by maintenance therapy with an immunotherapy drug called toripalimab to help your immune system fight the cancer.
Guangzhou, GuangdongAges 18–65 - NCT06851663RecruitingPhase 2/Phase 3
New PET scan for many solid tumors
This trial tests a new type of PET scan that uses a special antibody to find a marker called Trop2 on many common solid tumors. It may help doctors see tumors more clearly without needing a biopsy.
ShanghaiAges 18–75 - NCT06854380RecruitingEarly Phase 1
Steroid and enzyme injection for vocal cord lesions
This trial tests if injecting a steroid combined with hyaluronidase into vocal cord lesions can help people with voice problems who cannot or will not do voice therapy. It's for those with small, non-cancerous growths who aren't candidates for surgery.
Al Mansurah, Dakahlia GovernorateAges 18–60 - NCT06857890RecruitingPhase 1
Safety study of Grammidin throat spray in healthy volunteers
This trial tests a new throat spray called Grammidin With Anesthetic to see if it is safe and how the body processes it. Healthy volunteers take the spray and are monitored for side effects and drug levels in the blood.
MoscowAges 18–45 - NCT06859281RecruitingPhase 1
Safety of Grammidin throat spray in healthy adults
This trial tests the safety and how the body processes a new throat spray called Grammidin. Healthy volunteers will use the spray so researchers can see how it works and if there are any side effects.
Saint PetersburgAges 18–45 - NCT06860152Recruiting
Improving speech understanding in noise with cochlear implants
This study tests how well people with cochlear implants can understand speech in noisy situations, compared to those with normal hearing. It involves a special imaging scan to see how the brain processes sound, which may help improve future implant technology.
Iowa City, IowaAges 18–99 - NCT06867302Recruiting
Study on dexmedetomidine for agitation after nose surgery
This trial tests if a medicine called dexmedetomidine can help prevent agitation after nose surgery. You may be eligible if you are a healthy adult having planned nose surgery.
Al Fayyum, Faiyum GovernorateAges 18–50 - NCT06868433RecruitingPhase 1
TMV vaccine alone or with pembrolizumab for advanced HNSCC
This trial tests a vaccine made from your own tumor to help your immune system fight head and neck cancer that has returned or spread. It is given alone or with an immunotherapy drug (pembrolizumab) to see if it can shrink tumors or slow progression.
Atlanta, GeorgiaAges 18 years+ - NCT06870435Recruiting
Screening for nasopharyngeal cancer with blood tests
This study compares three different blood tests to see which works best for spotting nasopharyngeal cancer early in people at higher risk. If you live in certain areas of China, you may be able to join.
Zhuhai, GuangdongAges 30–69 - NCT06876259Recruiting
AI tool to reduce antibiotics for young children with colds
This trial tests whether an artificial intelligence (AI) tool can help doctors decide when antibiotics are not needed for young children with colds. It aims to reduce unnecessary antibiotic use.
Pittsburgh, PennsylvaniaAges 6 months–2 years - NCT06880367Recruiting
Sound training for tinnitus relief
This trial tests whether a sound-based training program (called Siopi) can reduce tinnitus. It uses brain wave recordings to see how the training changes brain activity.
OrléansAges 18–84 - NCT06881368Recruiting
Understanding Susac syndrome in adults
This study looks at Susac syndrome, a rare condition that affects the brain, ears, and eyes. If you have hearing loss, vision problems, or confusion, researchers want to understand what causes it and how it affects people like you.
ParisAges 18 years+ - NCT06882889Recruiting
Comparing domestic vs imported hearing aids for age-related hearing loss
This trial compares two types of hearing aids (one made in China, one imported) to see which works better for age-related hearing loss. You might benefit if you have moderate to severe hearing loss and are willing to test both devices.
Guangzhou, GuangdongAges 60–85 - NCT06883175Recruiting
New ways to measure how your esophagus works
This study uses special probes to measure the movement and pressure in your esophagus (the tube connecting your mouth to your stomach) to better understand swallowing problems like achalasia, GERD, and other conditions. The goal is to improve how doctors diagnose and treat these issues.
Chicago, IllinoisAges 18–85 - NCT06886347RecruitingPhase 1
New treatment for metastatic nasopharyngeal cancer before chemotherapy
This trial tests a new treatment for people with advanced nasopharyngeal cancer that has spread (stage IVb) and who have not yet had chemotherapy. It aims to see if the experimental treatment is safe and effective as a first option.
Hangzhou, ZhejiangAges 18–75 - NCT06887855Recruiting
Swallowing therapy for recent stroke patients
This trial tests two new exercises for people who have trouble swallowing after a stroke. If you had a stroke within the last six months and haven't tried swallowing therapy before, this may help you regain strength in your throat muscles.
Doha, Baladiyat ad DawhahAges 18–75 - NCT06890260Recruiting
Electroacupuncture plus microneedle for allergic rhinitis
This trial tests a 4-week treatment of electroacupuncture combined with microneedle knife for people with moderate to severe allergic rhinitis. It may help reduce symptoms without relying on standard allergy medications.
Hangzhou, ZhejiangAges 18–75 - NCT06890572Recruiting
Air purifiers for allergy symptoms relief
This study tests if using an air purifier at home can help reduce allergy symptoms like a stuffy or runny nose. It is for people with persistent moderate-to-severe allergic rhinitis caused by indoor allergens like dust mites or pet dander.
SeoulAges 19–60 - NCT06893458Recruiting
Feeding and quality of life in children with a tracheostomy
This study looks at how feeding problems and quality of life affect children who have a tracheostomy (a tube in the windpipe). It aims to understand what difficulties children and families face, so care can be improved.
Solna, Stockholm CountyAges Up to 18 years - NCT06894303Recruiting
Remote programming for cochlear implants in routine follow-up
This study tests if cochlear implants can be adjusted remotely (without visiting the clinic) during regular follow-ups. If you have a compatible implant and sound processor, you may be able to take part from home.
ParisAges 18 years+ - NCT06895824Recruiting
Tracking body sensations for tinnitus relief
This trial tests a new therapy that helps people with tinnitus learn to track body sensations. It may help reduce distress by changing how you relate to the ringing in your ears.
LondonAges 18 years+ - NCT06897501Recruiting
Comparing breathing tubes for voice box protection during esophagectomy
This trial compares two types of breathing tubes used during robot-assisted esophageal cancer surgery. One tube blocks one lung (double-lumen tube) and the other tube uses a smaller blocker (bronchial blocker); researchers want to see which causes fewer voice box nerve injuries after surgery.
SeoulAges 19 years+
Common questions
- How many ear, nose & throat clinical trials are recruiting?
- Clin2 is tracking 1,371 recruiting otolaryngology studies from the U.S. registry right now, out of 2,216 we cover in this area in total.
- What does “Ear, nose & throat” cover here?
- Hearing, balance, and conditions of the ears, nose, sinuses, and throat. We group each study into ear, nose & throat based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a ear, nose & throat trial near me?
- Use the search to filter ear, nose & throat studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.